• Title/Summary/Keyword: time factor

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Effects of Curculiginis Rhizoma on anti-thrombotic activity (선모(仙茅) 열수(熱水) 추출물(抽出物)의 항혈전(抗血栓) 효능 연구)

  • Roh, Seong-Soo
    • The Korea Journal of Herbology
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    • v.26 no.4
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    • pp.125-132
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    • 2011
  • Objectives : An aim of study is to investigate effects of curculiginis rhizoma in vitro (factor Xa (FXa) inhibitor assay, prothrombinase assay, prothrombin time (PT) assay, activated partial thromboplastin time (aPTT) assay) and in vivo experiment (blood clotting time, thromboxane B2 content assay in serum and weight of thrombus by AV-shunt rat model). Methods : We gained a human serum and used serum in vitro study such as factor X activity (FXa) inhibition, prothrombinase inhibition, prothrombin time (PT) and activated partial thromboplastin time. Fifteen SD rats were divided into three groups (intact control group and two experimental group treated with extract of Curculiginis Rhizoma(ECR)). Rats were orally administrated DW (intact control group), 600 mg/kg concertration of ECR and 200 mg/kg concertration of ECR. After one hour, we anesthetized rats and made arteriovenous (AV) shunt rat models to study weights of thrombus, took a hole blood to study content of thromboxane B2 and blood clotting time. Results : In vitro, ECR increased a inhibitory activity of FXa, prothrombinase and aPTT compared than intact control group. Especially ECR made significant increase of FXa and prothrombinase inhibitory activity (p<0.05, p<0.01). And PT were increased in ECR control group compared with intact control group. In vivo, a blood clotting time of experiment group treated with ECR 600 mg/kg were significantly increased compared with that of intact control group (p<0.05) and content of thromboxane B2 was significantly decreased in group treated with ECR 600 mg/kg in seum. The weight of thrombus were significantly reduced in group treated with ECR 600 mg/kg compared with intact control group (p<0.05). But in vivo experiment study, those of group treated with ECR 200 mg/kg were reduced compared with those of intact control group without statistical significance. Conclusions : ECR has a antithromboic activity in internal course with inhibitory activity of FXa and prothrombinase in vitro, it required to research more study for effective compounds.

Coupling loss factor evaluation using loss factor based on the SEA (SEA에 기초를 둔 손실계수를 이용한 결합계수의 평가)

  • 안병하;황선웅;김영종
    • Proceedings of the Korean Society of Precision Engineering Conference
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    • 1997.10a
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    • pp.568-571
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    • 1997
  • The overall aim of this paper is to determine coupling loss factor using loss factor and structural loss factor. For this purpose, two kinds of loss factor were adopted. One is loss factor of each sub structure, another is structural loss factor based on the complex welded or assembled structure. Using these two parameters, it is possible to derive the coupling loss factor which represent characteristic condition of SEA theory. Coupling loss factor of conjunction in complex structure was expressed as power balance equation. The derived equation for a coupling loss factor has been simplified on the assumption of one directional power flow between two sub structures. Using these conditions, it is possible to find the coupling loss factor equation. The comparison between theory of power transmission on conjunction and above equation, show a good agreement in simple beam structure. To check the effectiveness of above equation, it was adopted rotary compressor. Rotary compressor has three main conjunctions between shell and internal vibration part. This equation was applied to find out the optimum welding point with respect to reduce the noise propagation. It shows the effective tool to evaluate the coupling loss factor in complex structure.

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Evaluation of multi-lane transverse reduction factor under random vehicle load

  • Yang, Xiaoyan;Gong, Jinxin;Xu, Bohan;Zhu, Jichao
    • Computers and Concrete
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    • v.19 no.6
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    • pp.725-736
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    • 2017
  • This paper presents the two-, three-, and four-lane transverse reduction factor based on FEA method, probability theory, and the recently actual traffic flow data. A total of 72 composite girder bridges with various spans, number of lanes, loading mode, and bridge type are analyzed with time-varying static load FEA method by ANSYS, and the probability models of vehicle load effects at arbitrary-time point are developed. Based on these probability models, in accordance to the principle of the same exceeding probability, the multi-lane transverse reduction factor of these composite girder bridges and the relationship between the multi-lane transverse reduction factor and the span of bridge are determined. Finally, the multi-lane transverse reduction factor obtained is compared with those from AASHTO LRFD, BS5400, JTG D60 or Eurocode. The results show that the vehicle load effect at arbitrary-time point follows lognormal distribution. The two-, three-, and four-lane transverse reduction factors calculated by using FEA method and probability respectively range between 0.781 and 1.027, 0.616 and 0.795, 0.468 and 0.645. Furthermore, a correlation between the FEA and AASHTO LRFD, BS5400, JTG D60 or Eurocode transverse reduction factors is made for composite girder bridges. For the two-, three-, and four-lane bridge cases, the Eurocode code underestimated the FEA transverse reduction factors by 27%, 25% and 13%, respectively. This underestimation is more pronounced in short-span bridges. The AASHTO LRFD, BS5400 and JTG D60 codes overestimated the FEA transverse reduction factors. The FEA results highlight the importance of considering span length in determining the multi-lane transverse reduction factors when designing two-lane or more composite girder bridges. This paper will assist bridge engineers in quantifying the adjustment factors used in analyzing and designing multi-lane composite girder bridges.

A Study on Types of Behavior and Satisfaction Level on the Information on Internet Fashion Web Sites (패션웹사이트 이용실태와 정보만족도에 관한 연구)

  • 신수연;김희수
    • Journal of the Korean Society of Clothing and Textiles
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    • v.25 no.8
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    • pp.1500-1511
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    • 2001
  • The purpose of this study were (1) to analyze the current fashion web-sites on the internet, which were increasing rapidly in number, (2) to find out the users purchase experiences of fashion products at internet shopping malls and satisfaction level on the information provided by the fashion sites. The questionnaire was administered to 332 women & men and data were analyzed by frequency, mean, standard deviation, factor analysis, reliability analysis, ANOVA and t-test. The results of this study were as follows. The factors on the satisfaction of information fashion web-sites categorized as 5 areas: Economy$.$Convenience, Aesthetics $.$Recreation, Variety $.$Interests, Up-to dateness $.$Specialization, and Reliability$.$ Precision. On the factor of Economy$.$Convenience, the users who had more frequent access and who were in their 20’s expressed the higher level satisfaction. On the factor of Aesthetics$.$Recreation, the users who had longer periods of time of use, who had lower level of internet shopping mall involvement, and students appeared to be more satisfied. On the factor of Variety$.$Interests, the users marking higher level of satisfaction were those who had higher frequency of uses, who had shorter period of time of use, who had lower level of internet shopping mall involvement and were students. On the factor of Up-to-dateness$.$Specialization, higher level of satisfaction was shown among the users who had shorter period of time of use, who had higher frequency of uses, who were in their 20’s and who were students. There was no significant differences according to Reliability & Precision factor.

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Relation between Multiple Markers of Work-Related Fatigue

  • Volker, Ina;Kirchner, Christine;Bock, Otmar L.
    • Safety and Health at Work
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    • v.7 no.2
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    • pp.124-129
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    • 2016
  • Background: Work-related fatigue has a strong impact on performance and safety but so far, no agreed upon method exists to detect and quantify it. It has been suggested that work-related fatigue cannot be quantified with just one test alone, possibly because fatigue is not a uniform construct. The purpose of this study is therefore to measure work-related fatigue with multiple tests and then to determine the underlying factorial structure. Methods: Twenty-eight employees (mean: 36.11; standard deviation 13.17) participated in five common fatigue tests, namely, posturography, heart rate variability, distributed attention, simple reaction time, and subjective fatigue before and after work. To evaluate changes from morning to afternoon, t tests were conducted. For further data analysis, the differences between afternoon and morning scores for each outcome measure and participant (${\Delta}$ scores) were submitted to factor analysis with varimax rotation and each factor with the highest-loading outcome measure was selected. The ${\Delta}$ scores from tests with single and multiple outcome measures were submitted for a further factor analysis with varimax rotation. Results: The statistical analysis of the multiple tests determine a factorial structure with three factors: The first factor is best represented by center of pressure (COP) path length, COP confidence area, and simple reaction time. The second factor is associated with root mean square of successive difference and useful field of view (UFOV). The third factor is represented by the single ${\Delta}$ score of subjective fatigue. Conclusion: Work-related fatigue is a multidimensional phenomenon that should be assessed by multiple tests. Based on data structure and practicability, we recommend carrying out further studies to assess work-related fatigue with manual reaction time and UFOV Subtest 2.

Discrete-Time Sliding Mode Controller Design for Scanner system (Scanner System을 위한 Discrete-Time Sliding Mode Controller 설계)

  • 이충우;정정주
    • 제어로봇시스템학회:학술대회논문집
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    • 2000.10a
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    • pp.172-172
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    • 2000
  • In this paper, we propose a new discrete-time sliding mode controller for reference tracking. Stability of tracking error is analyzed. Design method of sliding surface for tracking control is proposed. Simulation and experimental results are included to show the effectiveness of the proposed method.

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Investigation into the Worst Stress Condition for an Accelerated Life Test of a Compressor in Refrigerators - Acceleration Factor and the Reducible Test Time under High Temperature - (냉장고용 압축기의 가속수명시험을 위한 가혹조건 탐색 - 고온 가혹조건에서의 가속계수와 단축 시험기간 -)

  • Jung, Y.M.;Joo, W.J.;Jeong, S.K.
    • Journal of Power System Engineering
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    • v.16 no.3
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    • pp.44-50
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    • 2012
  • The reliability qualification test is essential in order to ensure the life time of the product under the normal operation conditions when a new product is developed. The reliability qualification test period has an important impact on the development time of new product. Therefore, some researches to reduce the test time of reliability qualification test have been actively studied. Generally, accelerated life test is well known as one method that can save the test time of the reliability qualification test. This test is conducted under the higher stress condition than normal condition. So we need to investigate what factor affects to the higher stress condition. This paper shows the relationship between the acceleration factor and reliability qualification test period. Especially, we focused on the method to obtain effective acceleration factors under the high temperature condition. Through some experiments for a refrigerator's compressor, we were able to confirm how to increase acceleration factors and how to reduce the reliability qualification test period with minimum samples.

Understanding of F2 Metrics Used to Evaluate Similarity of Dissolution Profiles (유사인자를 사용하여 용출양상 유사성을 비교하는 방법에 대한 고찰)

  • Cho, Mi-Hyun;Kim, Jeong-Ho;Lee, Hyeon-Tae;Sah, Hong-Kee
    • Journal of Pharmaceutical Investigation
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    • v.33 no.3
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    • pp.245-253
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    • 2003
  • Dissolution profile comparsions can be done by virtue of the similarity factor $(f_2)$. It is a logarithmic reciprocal square root transformation of the sum of squared error of % dissolution differences between two profiles at several time points. It gives information on the degree of similarity between the two profiles: An $f_2$ value between 50 and 100 suggests the similarity/equivalence of the two dissolution curves being compared. The objective of this report was to provide a careful examination on the $f_2$ metrics in detail. It was shown that $f_2$ values exceeded 50, when relative differences in % dissolved between two products were less than 15% at all time points. The similarity factor value was also found to be greater than 50, in cases when absolute % dissolution differences were below 10% at all time points. Interestingly, the $f_2$ value was changed by the number of the time points selected for calculation. In particular, $f_2$ tended to have higher values, when the $f_2$ metrics used a large number of time points in which % dissolved reached plateau. Finally, since the similarity factor was a sample statistics, it was impossible to infer type I/II errors and sampling error. Despite certain limitations inherited in the $f_2$ metrics, it was easy and convenient to evaluate how similar the two dissolution profiles were.

Study of Dynamics of Allyl Chloride-2-Butanone Binary System Using Time Domain Reflectometry

  • Sudake, Y.S.;Kamble, S.P.;Patil, S.S.;Khirade, P.W.;Mehrotra, S.C.
    • Journal of the Korean Chemical Society
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    • v.56 no.1
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    • pp.20-27
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    • 2012
  • Complex permittivity spectra of Allyl Chloride (AC), 2-Butanone (2-BU) and their binary mixtures over the entire range of concentration were obtained using the Time Domain Reflectometry (TDR) technique in microwave frequency range at various temperatures. Static dielectric constant and relaxation time are obtained from complex permittivity spectra. Density ($\rho$) and refractive index ($n_D$) are also measured. These parameters are used to determine excess dielectric constant, excess inverse relaxation time, excess molar volume, excess molar refraction, polarity, Bruggeman factor and thermodynamic parameters viz. enthalpy of activation and entropy of activation. The values of static dielectric constant and relaxation time increases while density and refractive index decreases with the percentage of 2-Butanone in Allyl Chloride increases. Excess parameters were fitted to a Redlich-Kister equation.

Control of Humanoid Robots Using Time-Delay-Estimation and Fuzzy Logic Systems

  • Ahn, Doo Sung
    • Journal of Drive and Control
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    • v.17 no.1
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    • pp.44-50
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    • 2020
  • For the requirement of accurate tracking control and the safety of physical human-robot interaction, torque control is basically desirable for humanoid robots. Because of the complexity of humanoid robot dynamics, the TDC (time-delay control) is practical because it does not require a dynamic model. However, there occurs a considerable error due to discontinuous non-linearities. To solve this problem, the TDC-FLC (fuzzy logic compensator) is applied to humanoid robots. The applied controller contains three factors: a TDE (time-delay estimation) factor, a desired error dynamic factor, and FLC to suppress the TDE error. The TDC-FLC is easy to execute because it does not require complicated humanoid dynamic calculations and the heuristic fuzzy control rules are intuitive. TDC-FLC is implemented on the whole body of a humanoid, not on biped legs even though it is performed by a virtual humanoid robot. The simulation results show the validity of the TDC-FLC for humanoid robots.