• 대한치과보철학회지
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• 제43권6호
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• pp.745-750
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• 2005

Statement of problem. Resonance frequency analysis has been increasingly served as a non-invasive and objective method for clinical monitoring of implant stability. Many clinical studies must be required for standardized data using RFA. Purpose. This study was performed to evaluate RFA value changes in two anodized implant groups. Material and method. Among a total of 24 implants, twelve screw shaped implants as a test group (H2-R8.5) were manufactured, which had a pitch-height of 0.4 mm, an outer diameter of 4.3 mm, a length of 8.5 mm, and external hexa-headed, were turned from 5 mm rods of commercially pure titanium (ASTM Grade IV, Warantec Co., Seoul, Korea), and another twelve implants as a control group were $Br{\aa}nemark$ Ti-Unite MK4 (diameter 4.0 mm, length 8.5 mm). Each group was installed in tibia of rabbit. Two implants were placed in each tibia (four implants per rabbit). Test two implants were inserted in right side and control two in left side. ISQ values were measured using $Osstell^{TM}$ (Integration Diagnostics Ltd. Sweden) during fixture installation, and 12 weeks later and evaluated the RFA changes. Results. Mean and SD of baseline ISQ values of test group were $75.0{\pm}3.4$ and $68.7{\pm}8.1$ for control group. Mean and SO of ISQ values 12 weeks after implant insertion were $73.2{\pm}4.7$ for test group and $72.6{\pm}3.9$ for control group. There were no statistically significant differences between groups in ISQ values after 3 months (P>0.05). From the data, RFA gains after 3 months were calculated, and there was statistically significant difference between groups (P<0.05). Conclusion. Although there were RFA changes between groups, implant stability after experimental period shows alike tendency and good bone responses.

• Asian-Australasian Journal of Animal Sciences
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• 제14권2호
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• pp.250-257
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• 2001

An experiment was conducted to determine the effects of phytase supplementation to the diets containing different levels of non-phytate phosphorus (NPP). A $3{\times}2$ factorial arrangement of treatments was employed. There were three dietary NPP levels of control (C) (0.45% for starter diet and 0.35% for grower diet), C-0.1% NPP (0.35% for starter diet and 0.25% for grower diet), and C-0.2% NPP (0.25% for starter diet and 0.15% for grower diet) and two phytase levels (0 and 500 U/kg). Reduced dietary NPP decreased feed intake and weight gain and increased mortality whereas dietary phytase increased feed intake and weight gain and decreased mortality. Supplemental phytase improved availabilities of dry matter, crude fat, ash, P, Zn, Mg, and Cu whereas dietary NPP level did not affect availabilities of nutrients except decreased Zn availability and increased Cu availability in reduced NPP diets. Nutrient retention of N, ash, Ca, P, Mg, and Zn were linearly decreased as dietary NPP levels reduced but dietary phytase increased their retention. Reduced dietary NPP increased ash excretion but decreased P and Cu excretion while dietary phytase decreased N excretion. Weight, length, girth and contents of ash, Ca, P and Mg of tibia linearly decreased as dietary NPP levels reduced. Dietary phytase increased length and ash content of tibia. It is concluded that dietary phytase can reduce P excretion and alleviate adverse affects caused by feeding low dietary NPP. Effects of phytase were greater in the lower NPP diets.

• 한국가금학회지
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• 제18권3호
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• pp.197-208
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• 1991

본 연구는 한국재래오골계의 효율적 선발 및 육종계획을 위한 경제형질과 기타 개량 대상형질간의 유전상관 및 표현형 상관을 추정하고자 1987년 6월 18일부터 1989년 4월 6일까지 사육되어 온 재래오골계에 관한 제형질에 대한 자료를 분석하여 얻어진 결과를 요약하면 다음과 같다. 1. 경제형질과 체형간의 유전상관은 체중과 정강이 길이, 흉폭, 흉위 및 경골장간에 각각 0.210∼0.788, 0.321∼0.826, 0.610∼0.995 및 0.096∼0.503으로 정의 계수이었고, 초산일영과 정강이 길이, 흉폭, 후위 및 경골장간에 각각 0.555∼0.626, 0.149∼0.270, 0.370∼0.445 및 0.014∼0.124이었으며, 산란수와 정강이 길이, 흉폭, 후위 및 경골장간에 각각 -0.460∼-0.167, 0.162∼0.320, 0.076∼0.336 및 0.203∼0.312이었고, 난중과 정강이 길이, 흉폭, 흉위 및 경골장간에는 각각 0.132∼0.498, -0.236-0.410, 0.148∼0.755 및 -0.019∼0.593이었다. 2. 경제형질과 난구성분간의 유전상관은 체중과 난백중, 난황중 및 난각중간에 각각 0.083∼0.591, 0.110∼0.541 및 0.336∼0.7823. 정의 계수이었고, 초산일령과 난백중, 난황중 및 난각중간에는 각각 0.467∼0.692, 0.265∼0.631및 0.420∼0.519이었으며, 산란수와 난백중, 난황중 및 난각중간에는 각각 -0.578∼-0.240, -0.255∼-0.060 및 -0.477∼-0.313으로 낮은 부의 계수이었으며, 난중과 난백중, 난황중 및 난각중간에 각각 0.825∼0.939, 0.382∼0.564 및 0.374∼0.937로 높은 정의 추정치이었다. 3. 경제형질과 난질간의 유전상관은 체중과 난형지수, 난각두께, 난백고 및 Haugh units간에 각각 0.215∼0.367, 0.248∼0.650, 0.161∼0.624 및 0.157∼0.499이었고, 산란수와 난형지수, 난각두께, 난백고 및 Haugh units간에는 각각 -0.384∼-0.207, -0.557∼-0.306, -0.555∼-0.198 및 -0.582∼0.074로 부의 계수이었으며, 난중과 난형지수, 난각중, 난백고 및 Haugh units간에는 각각 0.276∼0.697, 0.290∼0.627, 0.238∼0.538 및 -0.207∼0.020이었다. 4. 난구성분과 난질간의 유전상관에서 난백중과 난형지수, 난각두께, 난백고 및 Haugh units간에는 각각 0.100∼0.584, -0.380∼-0.002, 0.239∼0.887 및 -0.195∼0.279이었고, 난황중과 난형지수, 난각두께, 난백고 및 Haugh units간에는 각각 -0.204∼0.160, -0.294∼0.133, -0.049∼0.133 및 -0.196∼-0.136이었고, 난각중과 난형지수, 난곡두께, 난백고 및 Haugh units간에는 각각 0.127∼0.503, 0.127∼0.476, 0.140∼0.273 및 -0.172∼0.223으로서 난각중 과 Haugh units를 제외하고는 정의 상관계수이었다.

• Journal of Trauma and Injury
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• 제26권3호
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• pp.163-169
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• 2013

Purpose: This study was conducted to confirm the anatomic conformity of the new periarticular locking plates designed by Zimmer on Korean adult bones and to identify the structures at risk during the application of these implants. Methods: The study was performed on the humerus, radius, and tibia of 10 adult cadavers(6 males and 4 females) procured from the cadaveric lab of our hospital. Anteroposterior (AP) and lateral X-rays were taken to confirm that the cadavers were free of any unusual lesions or anatomic variations. We used the 3.5-mm proximal humerus plate, 2.7-mm distal radius plate, 3.5- and 5.0-mm proximal tibia plates, and 3.5-mm distal tibia plate developed by Zimmer, Inc. (Zimmer periarticular locking plate). The longest plate from each group was used to confirm anatomical conformity. Standard approaches were used for each area, and soft tissue was retracted in order to pass the plate beneath the muscle. The position of the plate was confirmed using standard AP and lateral view X-rays. After this procedure had been completed, the region was dissected along the length of the implant to determine the conformity of the implant to bone and the penetrations of screws into the articular surface or violations of any vital structures, such as nerves, blood vessels, or tendons. Results: Excellent anatomical conformity was observed with Zimmer periarticular locking plates for Korean adults. The tibial nerve and the posterior tibial artery were found to be structures at risk when applying a distal tibial plate. Conclusion: Additional posterolateral fixation is recommended when dealing with cases of tibial plateau fracture when the fracture line extends to the posterolateral cortex. We recommend taking proper views using 10~15 degrees of internal rotation to ensure correct screw length and, thus, avoid penetration of vital structures and tendons.

• 대한치과교정학회지
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• 제36권5호
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• pp.324-330
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• 2006

Sandblasted large grit, acid etched(SLA)표면처리 된 교정용 미니 임플랜트와 평활면을 가진 교정용 미니 임플랜트 사이에 제거회전력과 조직학적 소견을 통해 표면처리된 교정용 임플랜트의 임상적 가능성에 대하여 알아보고자 하였다. 실험재료로는 길이가 9.5 mm, 외경이 1.8 mm인 custom made, screw shaped, titanium implants가 사용되었다. 미니 임플랜트는 두개의 군으로 분류되었는데 SLA군은 20개의 SLA 표면처리된 미니 임플랜트이었고, 평활면군은 크기와 형태가 같지만 SLA처리공정이 생략되어 제작된 20개의 미니 임플랜트로 구성되었다. 이들은 10마리 가토의 경골에 식립되었다. 각각의 가토의 우측 경골에는 SLA군의 미니 임플랜트 2개가 식립되었고, 좌측 경골에는 평활면군의 미니 임플랜트 2개가 식립되었다. 각 군에는 식립 직후 Ni-Ti coil spring에 의해 약 150 g의 지속적인 견인력이 주어졌다. 식립 6주 후에 10마리의 가토를 희생하였고, 안정된 상태에서 Ni-Ti coil spring을 제거하였으며 digital torque gauge를 이용하여 제거 회전력을 측정하였다. 식립 6주 후에 SLA군의 경우 (8.29 Ncm) 평활면군 (3.34 Ncm)에 비해 더 높은 평균 제거회전력을 나타내었고 조직학적 소견에서도 screw 하방에서의 신생골 형성이 관찰되었다. SLA 표면처리된 미니 임플랜트는 평활면 미니 임플랜트에 비해 좀 더 강한 교정력에 저항할 수 있을 것으로 예상되었다.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제36권5호
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• pp.392-401
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• 2010

Introduction: Diabetes mellitus, as a major health problem for the elderly has been shown to alter the properties of the bone and impair bone healing around a titanium implant in both humans and animals. The aim of this study was to examine the effect of adipose-derived stem cells on the healing process around a titanium implant in streptozotocin-induced diabetic rats. Materials and Methods: Thirteen rats were divided into two groups: adipose-derived stem cells injected group and a control group. A titanium screw implant (diameter: 2.0 mm, length: 3.5 mm) was placed into both tibia of 13 rats: 13 right tibia as the control group and 13 left tibia as the experimental group. The rats were sacrificed at different intervals (1, 2, and 4 weeks) after implantation for histopathology observations and immunohistochemistric analysis. Results: The histopathological findings revealed earlier new formed bone in the experimental group than the control group. In particular, at 1 week after implantation, the experimental group showed more newly formed bone and collagen around the implant than the control group. In immunohistochemistric analysis, osteoprotegerin (OPG) expression in the experimental group increased early compared to that of the control group until 2 weeks after implantation. However, after 2 weeks, OPG expression in the experimental group was similar to OPG expression in the control group. The receptor activator of nuclear factor ${\kappa}B$ ligand (RANKL) expression in the experimental group increased early compared to that of the control group, and then decreased at 2 weeks. After 2 weeks, the level of RANKL expression was similar in both groups. Conclusion: These results suggest that adipose-derived stem cells in implantation can promote bone healing around titanium, particularly in diabetes mellitus induced animals.

• 한국식품영양학회지
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• 제34권6호
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• pp.568-575
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• 2021

The purpose of this study was to investigate the effects of extract mixture of C. wilfordii and P. umbrosa (IPLUS-CWPU) on bone growth in 4-week old young male SD rats. To confirm the effect of IPLUS-CWPU, we measured the length of bone growth plate, the ratio of proliferative zone to the length of growth plate and the expression level of insulin-like growth factor, IGF-1. The IPLUS-CWPU treatment shows a significant increase of tibial and femoral growth plate and the ratio of proliferative zone in growth plate. Especially, the length increased by 13.9% and 25.3% in the tibia and femur, respectively, in the high-dose group compared to the normal group. Moreover, the expression of IGF-1 gene in liver was upregulated in IPLUS-CWPU treated groups. These results indicated that IPLUS-CWPU administration could increase the proliferative zone of bone growth plate in early developmental stage by upregulation of IGF-1 gene.

• 대한족부족관절학회지
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• 제11권1호
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• pp.18-22
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• 2007

Purpose: To provide basic data on anatomy of the ankle joint in adults using magnetic resonance imaging as well as to compare measurements with available data of corresponding dimension in the different sizes of the total ankle replacements design ($HINTEGRA^{(R)}$). Materials and Methods: Magnetic resonance (MR) sagittal and coronal images from one hundred-forty nine were studied. Post traumatic, arthritic, or grossly deformed ankles at any reason were excluded. Lengths, widths of the main parts of this articulation and also the radius of curvature of talar dome were measured in the MR images. Statistical analysis was performed on these measurements. Results: On MR coronal image data, average tibial width was $30.0{\pm}4.1\;mm$ and talar width was $27.0{\pm}3.4\;mm$. On sagittal image date, average anteroposterior length of the distal tibia was $39.0{\pm}4.2\;mm$, average anteroposterior length of the talus was $31.3{\pm}2.8\;mm$, and average sagittal radius of curvature of talar dome was $20.1{\pm}2.9\;mm$. All measurements in male were significantly larger than in female (p<0.01), but a significant difference according to age was not found. Conclusion: Ankle morphometric data define a basis of size, particularly useful in the design of ankle prostheses.

• 한국전문물리치료학회지
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• 제6권1호
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• pp.1-14
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• 1999

The quadriceps angle (Q angle) has been used to reflect the quadriceps muscle's force on the patella in the frontal plane. Previous investigations of the Q angle and it's relationship to knee disorders have yield equivocal results. The purpose of this study was to analyze the factors related to the Q angle and it's relation to other variables such as leg length, body weight, CTA (calcaneus to tibia angle), TOA (toe out angle), and pelvic width in normal subjects. The participants were 60 students (30 men and 30 women) who had no orthopedic and neurological impairments, aged from 20 to 29 years of age, with an average age of 22.1 years. Prior to participation, each subject was informed of the procedures of the experiment from a researcher and assistant researchers. The equipment used in this study were modified standard goniometer, ruler, marking pen, and Martin apparatus for pelvic width. In order to determine the statistical significance of the experiment, regression analysis, independent t-test, and Pearson correlation were used at the 0.05 level. The results were as follows: 1) It was found that the Q angle of women is greater than that of men's from both knees. 2) There was no significant difference between right and left quadriceps angle. 3) The Q angle decreased as the body weight (leg length) shifted from low to high. 4) It seems that factors related to the Q angle were body weight, CTA, and pelvic width, but there was no significant difference at the 0.05 level.

• Archives of Reconstructive Microsurgery
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• 제15권1호
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• pp.26-32
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• 2006

Purpose: The purpose of this study was to evaluate the effectiveness of limb reconstruction and functional recovery using vascularized fibular graft in the treatment of extensive bone defect of long bone caused by various diseases. Materials and Methods: From september 1995 to March 2005, 21 patients with segmental bone defects were managed with vascularized fibular graft: 13 males and 8 females, aged 39 years on average (range, $8{\sim}65\;years$). The reconstructed site was the humerus in 9 patients, the femur in 5, the tibia in 4 and the forearm bone in 3. The length of bone defect ranged from $8{\sim}17\;cm$. Results: Twenty grafts were successful. The mean period to obtain radiographic bone union was 5.7 months on average. Conclusion: Fibular grafts allow the use of a segment of diaphyseal bone and of sufficient length to reconstruct most skeletal defects of the long bone. The vascularized fibular graft is indicated in patients with intractable nonunions where conventional bone grafting has failed or large bone defects.