• Title/Summary/Keyword: thiadiazolines

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Synthesis of C-(2-Furyl)-N-(4-nitrophenyl)methanohydrazonyl Bromide. Reactions with Nucleophiles and Active Methylene Compounds

  • Hassaneen, Hamdi M.;Shawali, Ahmad S.;Elwan, Nehal M.;Ibrahim, Al Hossien A.
    • Archives of Pharmacal Research
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    • v.14 no.3
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    • pp.266-270
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    • 1991

  • Synthesis of C-(2-furyl)-N-(4-nitrophenyl)methanohydrazonyl bromide 2 is described. Treatment of 2 with uncleophiles affords the corresponding substitution products 3-7. Also, compound 2 reacts with selenocyanate anion and thiocyanate anion and give the corresponding selenadiazoline and thiadiazoline 8 and 9, respectively. Moreover, reaction of 2 with enolates of various active methylene compounds afforded the pyrazole derivatives 17-20.

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