• Journal of Korean Biological Nursing Science
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• 제11권1호
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• pp.77-84
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• 2009

Purpose: This study was performed to investigate outbreak, treatment, and lifestyle in children with atopic dermatitis (AD) for developing a health promotion education program. Method: Data were collected from 2,920 children with AD in preschool and elementary schools in K city. Result: The majority of children (43.75%) were onset in less than 1 yr after the birth. The locations of skin lesion were face, extension of extremities, and flextion of extremities, neck and trunk. The types of treatment were complement therapies, and medical treatment such as pediatrics and dermatology. Their parents chose a type of treatment for their children. Of complement therapies, the most common type was aroma oil. Herbal medicine was the most eating type among complement therapies. In lifestyle, the preferred bathing method was shower. In applying moisturizer, the most common time was within 3 min after bath. The highest frequency of taking instant/processed diet was 1-2 times per week and the most preferred type was pork. Conclusion: A Health promotion educational program with AD in preschool and elementary school children should included a specificity of disease, the recent treatment guideline, life therapy and evidenced complement therapy by child and family unit for the promotion of their health.

• 가정∙방문간호학회지
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• 제9권2호
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• pp.90-102
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• 2002

Purpose: Home health nurses could affect patients' choice of alternative therapy. This study was carried out to investigate home health nurses' attitudes and cognition toward alternative therapy. Method: The subjects were 92 nurses who preparing the home health nurses at 2 university in Seoul and Suwon. Using the questionnaire. we measured the subjects' attitudes and cognition toward alternative therapy. Result: The mean score of attitudes about application was 3.14. and the score of attitudes about therapeutic effect was 2.57. The score of attitudes about therapeutic effect were significantly positive correlation to the score of cognition about alternative therapy. The attitudes about therapeutic effect were different significantly according to number of working years. But they commonly wanted to apply the soojichim. aroma-therapy. massage. danjon breathing. music therapy. plant therapy. and foot reflexology to their home health care subjects. Conclusion: Alternative therapies became a popular source of health care in Korea. This study showed pre-home health nurses had positive attitudes toward alternative therapies and they had wide variations of knowledge in how to use each therapy. But they acknowledge the value of alternative therapies as useful nursing interventions. so we all nurses should pay attention to develope the nursing intervention using alternative therapy.

• 대한한방내과학회지
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• 제32권3호
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• pp.361-370
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• 2011

Objectives : The aim of this study was to collect and analyze studies of moxibustion therapies of stroke, also suggesting the method of study about moxibustion therapies. Methods : In this study, electronic searches were performed with searching sites. Search words such as: "중풍", "뇌졸중", "stroke", "CVA", "뜸", "구", "moxibustion", and "moxa" were used as a single keyword or in combinations. Results : Through searching, 23 studies were included. In the study domain, 20 treatment theses were found (87%), in the study category, 20 clinical trials were found (87%), and in the thesis form, 10 RCT were found (43%). Acupuncture points such as CV4 were most frequently used. In the periods of study, 5 theses took 4 weeks to complete. In the assessment of disease, 7 theses were about urinary disorder which was the most in numbers. 17 out of 20 clinical theses showed significant results. Conclusions : The study of moxibustion therapies for stroke needs to standardize moxibustion therapies, and present many high quality and various thesis designs.

• 대한한의학회지
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• 제41권3호
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• pp.9-21
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• 2020

Objectives: This study is to understand and develop Acupuncture treatment in Korean Medicine(韓醫學). Methods : Firstly, the definitions of Acupuncture Prescription(鍼 處方) and Methods of Acupuncture Therapies(鍼法) were clarified. Secondly, the results from the researches of previously existing Acupuncture Prescriptions(鍼 處方) were analyzed. Results ＆ Conclusions : Acupuncture Prescription(鍼 處方) represents the results achieved from combining Acupuncture Points(腧穴) according to the symptoms of diseases. Methods of Acupuncture Therapies(鍼法) denote methodologies for proposing Acupuncture Prescriptions(鍼 處方) which were accomplished by combining Acupuncture Points(腧穴) based on a specific theory. The existing methods of combining Acupuncture Points(腧穴) derived from the analysis of Acupuncture Prescription (鍼 處方) have a meaning in suggesting a direction for acupuncture treatments. However, deficiencies still exist to restore the absence of universality and objectivity in acupuncture treatment. Researches on Methods of Acupuncture Therapies(鍼法) based on the principle are required accordingly. The concept of hierarchy exists in Acupuncture Prescription(鍼 處方) and it ranks Acupuncture Points(腧穴) as primary and secondary according to the indications of the Acupuncture Points(腧穴). Since there is the time difference in needling process, the concept of hierarchy is fulfilled through the needling procedure.

• Clinical and Experimental Reproductive Medicine
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• 제40권1호
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• pp.38-41
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• 2013

Liver damage induced by ovarian stimulation has been demonstrated in some cases reported in the literature. However, there has never been a fruitful debate on this topic. The present manuscript tried to fill this gap. We reported a case of a 35-year-old nulliparous woman admitted to our obstetric emergency room for severe pre-eclampsia. She had been subjected to four cycles of controlled ovarian stimulation for intrauterine insemination. At 32 weeks of gestation, she developed severe pre-eclampsia, which led to HELLP syndrome complicated by fatal liver failure. The etiological link between ovarian stimulation and HELLP syndrome is intriguing. Further investigations are needed to understand whether repeated ovarian stimulation may represent a risk factor in pre-eclamptic patients.

• Asian Pacific Journal of Cancer Prevention
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• 제17권2호
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• pp.473-478
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• 2016

Hepatocellular cancer is a very common cause of cancer related deaths worldwide. Only 30-40% of patients present with early-stage disease open to curative treatments, such as resection or transplantation, while others can only undergo local therapies or palliative care. Various trans-arterial approaches have been used for treatment of hepatocellular carcinoma in patients who need a down-staging to liver transplantation, and who are not candidates for transplantation or radiofrequency ablation. Transarterial chemoembolization (TACE), transarterial embolization (TAE), drug-eluting beads, and radioembolization have been used for locoregional control, and have been shown to prolong the overall survival when compared with supportive care. In this review, we discuss patient selection, pre- and post-procedure imaging, techniques, safety, and clinical outcomes related to these therapies. Newer advances with future directions in various fields related to trans-arterial therapies are also discussed.

• 셀메드
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• 제5권2호
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• pp.13.1-13.5
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• 2015

Many patients with psoriasis look for treatment options other than conventional treatment to control their disease with less side effects. We evaluated the prevalence and characteristics of herbal therapy usage among patients with psoriasis in Turkey. A self-prepared questionnaire about herbal therapies was applied to the psoriatic patients attended our dermatology clinic between October 2013 and December 2013. A total of 100 patients (55 male, 45 female; 7 - 80 years of age) were included in this study. Fortynine percent of patients used at least one form of herbal therapies. Juniperus oxycedrus and Aloe vera were found to be the most frequently used plants. 36.7% of the patients get benefit from herbal therapy. Only 12.2% of patients had informed their clinicians during or after herbal therapy usage. 22.4% of the patient had continued conventional treatment during herbal therapies. Side effects related with herbal therapy were developed in 26.5% of the patients. The risk of side effects was found to be 5.23 times more in patients using phytotherapies systemically compared with ones using topically. Our results show that herbal therapy usage is common among patients with psoriasis in Turkey. Since herbal therapies have the potential of interacting with the medical treatment modalities and causing life threatening allergic reactions, clinicians should be aware of plants used in psoriasis and possible adverse reactions related with them and also should not forget asking about herbal therapy history.

• 기본간호학회지
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• 제9권3호
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• pp.399-411
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• 2002

Purpose: This study was done to investigate the application of complementary and alternative therapies (CAT) in patients with chronic liver disease. and to analyze the Influence of health locus of control (HLOC) on CAT. Method: Questionnaires on CAT and a multidimensional health locus of control (MHLOC) scale developed by Wallston and Wallston were completed by 141 patients. Result: Analysis showed that 44.7% of the patients had experience with CAT and 49.2% of the patients reported being willing to use CAT. Reliability scores for the scale were HLOC-I 0.7376, HLOC-P 0.6383, HLOC-C 0.7351. The mean scores for the HLOC were HLOC-I 24.86, HLOC-P 22.86, HLOC-C 16.00. There were no significant differences in mean scores for HLOC between the patients who had used CAT and those who had not. Eight response Patterns for HLOC were identified. Among them, 'yea sayer' was the largest group (27.0%). A significant difference was found in the 'yea sayer' pattern between the group who had used CAT and the group who had not. Conclusion: CAT relates to various cognitive factors such as HLOC. Further study is needed to examine the influence of HLOC on CAT and its response patterns.

• 대한소화기학회지
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• 제72권5호
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• pp.237-244
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• 2018

While the prevalence of Helicobacter pylori (H. pylori) infection is decreasing in Korea, the incidence of gastric cancer remains high, emphasizing the importance of H. pylori eradication. A new treatment strategy is needed as the eradication rate with standard triple therapy, which is currently the standard first-line regimen for H. pylori infection, has decreased below the optimum level. The major cause of eradication failure is increased antibiotic resistance. Sequential, concurrent, and hybrid therapies that include clarithromycin produce higher eradication rates than conventional standard triple therapy. However, the effectiveness of these treatments is limited in regions where the resistance rate to various antibiotics is high. Bismuth quadruple therapy is another alternative therapy, but again the eradication rate is not sufficiently high. Tailored therapy based on individual characteristics, including antibiotic susceptibility, may be ideal, but there are several limitations for clinical application and further research is needed. New potassium-competitive acid blocker-based therapies could emerge as effective alternatives in the near future. A consensus is needed to establish a strategy for applying new eradication therapies in Korea.

• Biomolecules & Therapeutics
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• 제31권1호
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• pp.1-15
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• 2023

Autophagy is a process of eliminating damaged or unnecessary proteins and organelles, thereby maintaining intracellular homeostasis. Deregulation of autophagy is associated with several diseases including cancer. Contradictory dual roles of autophagy have been well established in cancer. Cytoprotective mechanism of autophagy has been extensively investigated for overcoming resistance to cancer therapies including radiotherapy, targeted therapy, immunotherapy, and chemotherapy. Selective autophagy inhibitors that directly target autophagic process have been developed for cancer treatment. Efficacies of autophagy inhibitors have been tested in various pre-clinical cancer animal models. Combination therapies of autophagy inhibitors with chemotherapeutics are being evaluated in clinal trials. In this review, we will focus on genetical and pharmacological perturbations of autophagy-related proteins in different steps of autophagic process and their therapeutic benefits. We will also summarize combination therapies of autophagy inhibitors with chemotherapies and their outcomes in pre-clinical and clinical studies. Understanding of current knowledge of development, progress, and application of cytoprotective autophagy inhibitors in combination therapies will open new possibilities for overcoming drug resistance and improving clinical outcomes.