• Proceedings of the Korean Society of Plant Biotechnology Conference
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• 2003.10a
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• pp.62-62
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• 2003

• Proceedings of the Korean Society of Developmental Biology Conference
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• 2005.10a
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• pp.147-148
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• 2005

• Proceedings of the Korean Society of Embryo Transfer Conference
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• 2005.10a
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• pp.147-148
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• 2005

• Proceedings of the Zoological Society Korea Conference
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• 2001.10a
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• pp.240.1-240
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• 2001

No Abstract, See Full Text

• 한국생물공학회:학술대회논문집
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• 2005.10a
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• pp.911-911
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• 2005

• Proceedings of the Korean Society of Plant Pathology Conference
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• 2005.10a
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• pp.70-72
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• 2005

• Proceedings of the PSK Conference
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• 2000.04a
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• pp.150.1-150.1
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• 2000

• Proceedings of the Korean Society of Crop Science Conference
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• 2020.06a
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• pp.170-170
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• 2020

• Journal of Life Science
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• v.14 no.4
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• pp.716-725
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• 2004

Sox protein family, a transcription factor, has been found in whole animal kingdom, and contains a sequence-specific DNA binding domain called high mobility group domain (HMG). The Sox protein family based on the amino acid sequence of HMG domain was classified into 10 groups. Each group of Sox family shows significant conservation from nematode to human. The HMG domain affect to various developmental cell differentiation through binding to enhancer and regulating other transcription factors. Recently, many molecular biologists focus their research on the illustration of Sox-related disease, evolution and phylogeny. Especially, stem cell research with Sox gene family is indispensable field for understanding of their biological functions. The understanding of Sox genes may contribute to understand their role in human genetic disease and whole animal evolution.

• The Korean Journal of Food And Nutrition
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• v.24 no.4
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• pp.501-508
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• 2011

Previous studies suggest that polyunsaturated fatty acids with long carbon chains such as eicosapentaenoic acid(EPA) and docosahexaenoic acid(DHA) have several health benefits. However metabolic consequences of these fatty acids themselves and their regulation of transcriptional activity involving glucose utilization are not well established. Thus, the purpose of this study was to investigate how EPA influx affects cellular lipid accumulation and gene expressions involving $de$ $novo$ lipogenesis in hepatocyte cultures. Compared to oleic acid treatment, EPA treatment showed remarkably decreased cellular TG conversion and accumulation, along with phospholipids at a lower extent. As expected, EPA increased mRNA expression involving fatty acid influx and lipid droplet formation, but did not affect mRNA expression involving glucose utilization. EPA increased transcriptional activity of PPAR-${\alpha}$ and glucose responsive transcription factor when transcription factor binding protein was activated. Taken together, these data suggest that EPA decreases lipid accumulation through increases of the ${\beta}$-oxidation pathway without interruption of glucose utilization.