• Journal of Periodontal and Implant Science
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• 제49권5호
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• pp.299-309
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• 2019

Purpose: To analyze the ridge profile of the anterior maxilla using cone-beam computed tomography and to assess the clinical significance of the ridge profile by performing virtual implant placement. Methods: Thirty-two cone-beam computed tomography scans of anterior maxillae were included. For each tooth, a vertical line was made along the longitudinal axis, and 3 horizontal lines at 1-, 3-, and 5-mm levels below the labial bone crest were drawn perpendicularly to the vertical reference. At these levels, the thickness of the alveolar ridge (RT), and the labial (LT) and palatal bone plate (PT) were measured. Then, virtual implant placement using standard and tapered implants was performed. A generalized linear mixed model was used for statistical analysis. Results: The teeth were located labially based on the proportion of LT and PT with respect to RT. At the 1-mm level, the value of LT was between $1.0{\pm}0.4mm$ for central incisors and $1.3{\pm}0.6mm$ for canines. A large number of teeth had area(s) with less than 1-mm-thick labial bone between the 1- and 5-mm levels below the crest. The mean PT was generally thicker than the LT in all tooth types. The greatest mean value of labial concavity was observed for canines, compared to other tooth types. Men had a greater RT than did women, but had a comparable LT. Less apical fenestration was observed when tapered implants were used. Conclusions: Most teeth in the anterior maxilla had a thin labial bone plate, with no significant difference between sexes. Tapered implants may be advantageous for the anterior maxilla.

• 한국근적외분광분석학회:학술대회논문집
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• 한국근적외분광분석학회 2001년도 NIR-2001
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• pp.1615-1615
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• 2001

During the past ten years, Near Infrared Spectroscopy has been successfully applied to the analysis of a great variety of agriculture products. Previous works (Morra et al., 1991; Salgo et al., 1998) have shown the potential of this technology for soil analysis, estimating different parameters just with one single scan. The main advantages of NIR applications in soils are the speed of response, allowing the increase of the number of samples analysed to define a particular soil, and the instantaneous elaboration of recommendations for fertilization and soil amendment. Another advantage is to avoid the use of chemical reagents at all, being an environmentally safe technique. In this paper, we have studied a set of 129 soil samples selected from representative glasshouse soils from Southern Spain. The samples were dried, milled, and sieved to pass a 2 mm sieve and then analysed for organic carbon, total nitrogen, inorganic nitrogen (nitrate ammonium), hygroscopic humidity, pH and electrical conductivity in the 1:1 extract. NIR spectra of all samples were obtained in reflectance mode using a Foss NIR Systems 6500 spectrophotometer equipped with a spinning module. Calibration equations were developed for seven analytical parameters (ph, Total nitrogen, organic nitrogen, organic carbon, C/N ratio and Electric Conductivity). Preliminary results show good correlation coefficients and standard errors of cross validation in equations obtained for Organic Carbon, Organic Nitrogen, Total Nitrogen and C/N ratio. Calibrations for nitrates and nitrites, ammonia and electric conductivity were not acceptable. Calibration obtained for pH had an acceptable SECV, but the determination coefficient was found very poor probably due to the reduced range in reference values. Since the estimation of Organic Carbon and C/N ratio are acceptable NIIRS could be used as a fast method to assess the necessity of organic amendments in soils from Mediterranean regions where the low level of organic matter in soils constitutes an important agronomic problem. Furthermore, the possibility of a single and fast estimation of Total Nitrogen (tedious determination by modifications of the Kjeldahl procedure) could provide and interesting data to use in the estimation of nitrogen fertilizer rates by means of nitrogen balances.

• 한국산업보건학회지
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• 제4권2호
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• pp.208-223
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• 1994

The purpose of this study was to evaluate the efficiency of diffusive(or passive) sampler in measuring airbone organic solvents. Diffusive samplers are generally simple in construction and do not require power for operation. The efficiency of the diffusive samplers has not sufficiently been investigated in Korea. Three types of samplers were studied in this study. The sampling and analytical results by passive samplers were compared with results by charcoal tube method recommended by NIOSH(National Institute for Occupational Safty and Health). The following characteristics are identified and studied as critical to the performance passive monitors; recovery, reverse diffusion, storage stability, accuracy and precision, face velocity and humidity, n-Hexane, TCE(trichloroethylene) and toluene were used as test vapors. A dynamic vapor exposure system consisting of organic vapor generator and sampling chamber for evaluating diffusive samplers are made. The results of the study are summarized as follows. 1. NIOSH recommands that the overall accuracy of a sampling method in the range of 0.5 to 2.0 times the occupational health standard should be ${\pm}25$ percent for 95 percent confidence level. Among three types of diffusive samplers, sampler A has permeation membrane and samplers Band C have diffusive areas, samplers A and B met the criterion that overall accuracy for 95% confidence level of the samplers were within ${\pm}25$ percent of the reference value. Sampler C had overall accuracy ${\pm}9.6%$ and ${\pm}11.8%$ in hexane and TCE, respectively. The concentration of toluene was overestimated in sampler C with overall accuracy of ${\pm}43.9%$. 2. The desorption efficiencies of diffusive samplers were 96-107%. 3. There was no significant sampe loss during four weeks of storage both with and without refrigeration. 4. There was no significant reverse diffusion, when the samplers were exposure to clean air for 2 hours after sampling for 2 hours at the level of 2 TLY. 5. In case of 8 hours sampling, relative differences(RD) of concentrations between charcoal tube method and diffusive method were 15-39%, 13-46%, and 4-35% for sampler A, B and C, respectively. The performance was poor in 8 hours sampling for multiple substance monitors. 6. At high velocity(100 cm/sec), samplers B and C overestimated the concentrations of organic vapors, and sampler A with permeation membrance gave better results. 7. At 80% relative humidity, samplers showed no siginificant effect. Low humidity also did not affect the diffusive samplers.

• 방송공학회논문지
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• 제13권4호
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• pp.452-462
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• 2008

본 논문에서는 디지털 라디오와 지상파 Digital Multimedia Broadcasting (DMB)에서 사용되는 MUSICAM 이라 불리는 MPEG-1/2 Layer-II 와 MPEG-4 ER-BSAC 디코더를 330 MHz 클럭수를 가지고 동작하는 고정 소수점 digital signal processor (DSP) TMS320C64x+ 상에 실시간 구현한다. 오디오 디코더의 실시간 구현하기 위해, 다음과 같은 여러 단계의 최적화를 수행한다. 첫 째, 메모리 공유, 데이터 타입 재설정 및 루프의 unrolling 과정을 통해, C 코드 레벨에서 최적화를 수행한다. 다음으로, 비트스트림 분석의 재구성, 합성 필터의 변경 및 합성 필터의 윈도우 계수의 재배열을 통해 알고리즘 레벨에서 최적화를 수행한다. 또한, MPEG-1/2 Layer-II 디코더의 합성필터 모듈을 linear assembly program 레벨로 치환한다. Linear assembly program 레벨로 치환하는 이유는 MPEG-1/2 Layer-II 디코더에서 합성 필터 모듈이 가장 많은 계산량을 차지하기 때문이다. 구현된 오디오 디코더의 성능 평가를 위해, 복호화 처리시간의 비율을 측정하고, 최적화된 MPEG 디코더와 레퍼런스 MPEG 디코더로 처리된 오디오 신호 사이의 root mean square (RMS)를 계산한다. 최적화 실시간 구현 결과, MPEG-1/2 Layer-II 와 MPEG-4 ER-BSAC 디코더는 TMS320C64x+가 동작하는 최대 클럭 수의 3%와 11%의 사용으로 각각 동작하며, 오디오 디코더의 품질은 MPEG standard에 정의된 -77.01 dB의 조건을 모두 만족함을 확인할 수 있었다.

• Korean Journal of Radiology
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• 제24권3호
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• pp.235-246
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• 2023

Objective: It is difficult to predict the treatment response of tissue after stereotactic radiosurgery (SRS) because radiation necrosis (RN) and tumor recurrence can coexist. Our study aimed to predict tumor recurrence, including the recurrence site, after SRS of brain metastasis by performing a longitudinal tumor habitat analysis. Materials and Methods: Two consecutive multiparametric MRI examinations were performed for 83 adults (mean age, 59.0 years; range, 27-82 years; 44 male and 39 female) with 103 SRS-treated brain metastases. Tumor habitats based on contrast-enhanced T1- and T2-weighted images (structural habitats) and those based on the apparent diffusion coefficient (ADC) and cerebral blood volume (CBV) images (physiological habitats) were defined using k-means voxel-wise clustering. The reference standard was based on the pathology or Response Assessment in Neuro-Oncologycriteria for brain metastases (RANO-BM). The association between parameters of single-time or longitudinal tumor habitat and the time to recurrence and the site of recurrence were evaluated using the Cox proportional hazards regression analysis and Dice similarity coefficient, respectively. Results: The mean interval between the two MRI examinations was 99 days. The longitudinal analysis showed that an increase in the hypovascular cellular habitat (low ADC and low CBV) was associated with the risk of recurrence (hazard ratio [HR], 2.68; 95% confidence interval [CI], 1.46-4.91; P = 0.001). During the single-time analysis, a solid low-enhancing habitat (low T2 and low contrast-enhanced T1 signal) was associated with the risk of recurrence (HR, 1.54; 95% CI, 1.01-2.35; P = 0.045). A hypovascular cellular habitat was indicative of the future recurrence site (Dice similarity coefficient = 0.423). Conclusion: After SRS of brain metastases, an increased hypovascular cellular habitat observed using a longitudinal MRI analysis was associated with the risk of recurrence (i.e., treatment resistance) and was indicative of recurrence site. A tumor habitat analysis may help guide future treatments for patients with brain metastases.

• 한국건축시공학회지
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• 제18권2호
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• pp.125-132
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• 2018

본 연구에서는 UHPC의 인장성능을 파악하기 위해 직접 인장시험을 계획하였으며, 직접인장시험의 문제점으로 나타나는 균열 부위의 불규칙성을 시험체 중앙부 노치 도입을 통해 보완하였다. 또한 직접인장 시험 값의 편차 발생을 줄이기 위해 배치별로 구분한 다량의 시험체를 제작하여 신뢰성 높은 직접인장강도 값에 대한 참고자료로서 제시하는 것을 목적으로 하였다. 또한 현장 적용에 가장 적합한 강섬유 혼입률 1.5%에 대한 설계기준강도 120MPa의 배합을 양생조건을 두어 시험체의 역학적 특성 및 신뢰구간을 검토하였다. 결과적으로 압축강도 및 직접인장강도의 배치별 평균에 대한 편차는 큰 차이를 나타나지 않았으며, 직접인장 시험시 균열 위치는 모두 20mm 이내에서 발생하였다. 직접인장강도의 95% 신뢰구간에서는 평균 및 표준편차에서 범위가 상당히 작으며, 양생조건별 큰 차이가 발생하지 않았다. 결과를 통해 안전성 높은 직접인장시험이 이루어 졌으며, 배치별 시험체 제작 및 시험진행에 따른 신뢰성 높은 결과가 도출되었다고 판단된다.

• Korean Journal of Radiology
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• 제23권9호
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• pp.866-877
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• 2022

Objective: The optimal imaging approach for evaluating pathological nipple discharge remains unclear. We investigated the value of adding ductography to ultrasound (US) for evaluating pathologic nipple discharge in patients with negative mammography findings. Materials and Methods: From July 2003 to December 2018, 101 women (mean age, 46.3 ± 12.2 years; range, 23-75 years) with pathologic nipple discharge were evaluated using pre-ductography (initial) US, ductography, and post-ductography US. The imaging findings were reviewed retrospectively. The standard reference was surgery (70 patients) or > 2 years of follow-up with US (31 patients). The diagnostic performances of initial US, ductography, and post-ductography US for detecting malignancy were compared using the McNemar's test or a generalized estimating equation. Results: In total, 47 papillomas, 30 other benign lesions, seven high-risk lesions, and 17 malignant lesions were identified as underlying causes of pathologic nipple discharge. Only eight of the 17 malignancies were detected on the initial US, while the remaining nine malignancies were detected by ductography. Among the nine malignancies detected by ductography, eight were detected on post-ductography US and could be localized for US-guided intervention. The sensitivities of ductography (94.1% [16/17]) and post-ductography US (94.1% [16/17]) were significantly higher than those of initial US (47.1% [8/17]; p = 0.027 and 0.013, respectively). The negative predictive value of post-ductography US (96.9% [31/32]) was significantly higher than that of the initial US (83.3% [45/54]; p = 0.006). Specificity was significantly higher for initial US than for ductography and post-ductography US (p = 0.001 for all). Conclusion: The combined use of ductography and US has a high sensitivity for detecting malignancy in patients with pathologic nipple discharge and negative mammography. Ductography findings enable lesion localization on second-look post-ductography US, thus facilitating the selection of optimal treatment plans.

• 대한약침학회지
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• 제26권1호
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• pp.27-37
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• 2023

Objectives: Moroccan Arbutus unedo is an essential medicinal plant; however, little is known about the biological properties of its leaves mentioned in Moroccan traditional medicine. Methods: Various standard experiments were performed to evaluate the phytochemical, antidiabetic, antioxidant, antibacterial, and acute and sub-chronic toxicity characteristics of A. unedo leaves. Results: Phytochemical screening led to the identification of several phytochemical classes, including tannins, flavonoids, terpenoids, and anthraquinones, with high concentrations of polyphenols (31.83 ± 0.29 mg GAEs/g extract) and flavonoids (16.66 ± 1.47 mg REs/g extract). Further, the mineral analysis revealed high levels of calcium and potassium. A. unedo extract demonstrated significant antioxidant and anti-diabetic activities by inhibiting α-amylase (1.350 ± 0.32 g/mL) and α-glucosidase (0.099 ± 1.21 g/mL) compared to the reference drug Acarbose. Also, the methanolic extract of the plant exhibited significantly higher antibacterial activity than the aqueous extract. Precisely, three of the four examined bacterial strains exhibited substantial susceptibility to the methanolic extract . Minimum bactericidal concentration (MBC)/minimum inhibitory concentration (MIC) values indicated that A. unedo harbor abundant bactericidal compounds. For toxicological studies, mice were administered with A. unedo aqueous extract at single doses of 2,000 and 5,000 mg/kg. They did not exhibit significant abnormal behavior, toxic symptoms, or death during the 14-day acute toxicity test and the 90-day sub-chronic toxicity test periods. The general behavior, body weight, and hematological and biochemical status of the rats were assessed, revealing no toxicological symptoms or clinically significant changes in biological markers observed in the mice models, except hypoglycemia, after 90 days of daily dose administration. Conclusion: The study highlighted several biological advantages of A. unedo leaves without toxic effects in short-term application. Our findings suggest that conducting more comprehensive and extensive in vivo investigations is of utmost importance to identify molecules that can be formulated into pharmaceuticals in the future.

• Journal of Nutrition and Health
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• 제44권6호
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• pp.577-591
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• 2011

A food exchange system for diabetes is a useful tool for meal planning and nutritional education. The first edition of the Korean food exchange lists was developed in 1988 and the second edition was revised in 1995. With recent changes in the food marketplace and eating patterns of Koreans, the third edition of food exchange lists was revised in 2010 by the Korean Diabetes Association, the Korean Nutrition Society, the Korean Society of Community Nutrition, the Korean Dietetic Association and the Korean Association of Diabetes Dietetic Educators through a joint research effort. The third edition is based on nutritional recommendations for people with diabetes and focuses on adding foods to implement personalized nutrition therapy considering individual preferences in diverse dietary environment. Foods were selected based on scientific evidence including the 2007 Korea National Health and Nutrition Examination Survey data analysis and survey responses from 53 diabetes dietetic educators. While a few foods were deleted, a number of foods were added, with 313 food items in food group lists and 339 food items in the appendix. Consistent with previous editions, the third edition of the food exchange lists included six food categories (grains, meat, vegetables, fats and oils, milk, and fruits). The milk group was subdivided into whole milk group and low fat milk. The standard nutrient content in one exchange from each food group was almost the same as the previous edition. Korea Food & Drug Administration's FANTASY (Food And Nutrient daTA SYstem) database was used to obtain nutrient values for each individual food and to determine the serving size most appropriate for matching reference nutrients values by each food group. The revised food exchange lists were subjected to a public hearing by experts. The third edition of the food exchange lists will be a helpful tool for educating people with diabetes to select the kinds and amounts of foods for glycemic control, which will eventually lead to preventing complications while maintaining the pleasure of eating.

• 대한환경공학회지
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• 제32권8호
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• pp.739-746
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• 2010

본 연구의 목적은 1) 시료채취공간에서 ${\pm}10%$ 이내의 공기 유속을 가지는 챔버시스템을 제작하여, 2) 먼지(PM, particulate matter)측정을 위하여 사용되는 PM10과 PM2.5 시료채취기의 이론적 특성을 연구하고, 3) 실험을 통하여 본 연구에 사용된 먼지 시료채취기의 수행 특성을 평가하는데 있다. 챔버 내에서의 먼지 시료채취기의 수행능력을 측정하기 위하여 $20\;{\mu}m$의 공기역학중위입경과 2.0의 기하표준편차 특성을 가지는 옥수수전분을 분포하였다. 챔버 실험에 사용된 시료채취기는 미국 연방규정을 만족하는 각 1개의 APM PM10 및 APM PM2.5 시료채취기와 특수 제작된 3개의 소용량 시료채취기(2개 PM10과 1개의 PM2.5)를 사용하여 평균 공기 유속이 0.67 m/s와 2.15 m/s인 두 조건에서 각 1시간씩 3회 반복하여 총 6회의 실험을 실시하였다. 실험 결과, APM PM시료채취기를 기준 시료채취기로 사용하여 소용량 PM10과 PM2.5 시료채취기는 각 각 0.25와 0.39의 보정계수가 필요하며 이원 분산 분석을 통하여 두 개의 소용량 PM10 시료채취기의 평균 농도값 사이에는 유의적 차이가 있었다. 분리한계직경과 기울기(PM10: $10{\pm}0.5\;{\mu}m$와 $1.5{\pm}0.1$, PM2.5: $2.5{\pm}0.2\;{\mu}m$와 $1.3{\pm}0.03$)를 가지는 PM10과 PM2.5 시료채취기는 이론적으로 본 연구에 사용된 옥수수전분의 입자특성을 고려하여 86~114%와 64~152%의 먼지농도 범위를 채취하게 된다. 또한, 공기 중에 분포하는 입자의 공기역학중위입경이 해당 시료채취기의 분리한계직경보다 작을 때 시료채취기의 측정 질량농도는 이상적인 질량농도보다 크며, 반대의 경우 시료채취기는 작은 질량농도를 측정한다. 챔버 실험 결과, PM10과 PM2.5의 시료채취기는 각각 37~158%와 55~149% 범위를 가지며 이론적 계산농도보다 큰 범위의 질량 농도를 측정하였고 챔버 내 공기 유속이 2.15 m/s의 조건에서는 0.67 m/s와 비교하여 상대적으로 작은 먼지농도 범위를 가지며 이론적 계산농도와 유사한 먼지농도 범위가 측정되었다.