Objectives: This study was undertaken to investigate the effects of Yijin-tang and GamiYijin-tang on the gastrointestinal functions of rats Methods: Sprague-Dawley rats were used as experimental animals, and were administered Yijin-tang (Sample I group, 47.5 mg/ml) and GamiYijin-tang(Sample II group, 38.37 mg/ml, Sample ill group, 85.3 mg/ml) water extract once a day. Changes of gastric juice volume and intestinal mobility index were measured. The effects on colitis induced by dextran sulfate sodium in the rats were also observed. Results: 1. Gastric juice volume was decreased significantly in the sample I group (P<0.05) compared to the control group; there was not significant effect in the sample II and sample III groups. 2. The moving distance of carbon bolus was increased significantly in the sample n (p<0.05) and sample II (p<0.05) groups compared to the control group; there was not significant effect in the sample I group. 3. The intestinal mobility index was increased significantly only in the sample II group (P<0.05) compared to the control group. 4. The feces consistency was increased significantly on the 3rd and 5th day of the sample I group (P<0.05), on 3rd, 4th, and 5th day of the sample II (p<0.05) and the sample III (p<0.05) groups compared to the control group. 5. The feces property index was increased significantly only on the 5th day of the sample III group (p<0.05) compared to the control group. 6. The number of WBC and RBC, levels of hemoglobin and hematocrit were not changed in all sample groups compared to the control group. 7. The number of the type B Goblet cells were increased significantly in the sample II (p<0.05) and the sample III (P<0.05) groups, but the number of the type C Goblet cells were decreased significantly only in the sample ill group (P<0.05) compared to the control group. Conclusions: According to the above results, GamiYijin-tang compared to the Yijin-tang were decreased hight significantly in gastrointestinal mucose and histological antidiarrheal function with protection of the goblet cell more excellently were observed.
This study was conducted to investigate the quality characteristics of mungbean starch gels containing various hydrocolloids (carrageenan, locust bean gum and xanthan gum) during room temperature storage ($25^{\circ}C$ for 24, 48 and 72 hours). Carrageenan and xanthan gum reduced the pasting viscosity of mungbean starch, whereas the locust bean gum increased the viscosity. The melting characteristics, as assessed by DSC, showed that carrageenan and xanthan gum delayed gelatinization of mungbean starch and the locust bean gum had no effect on this property. The lightness (L) of the gels with the locust bean gum was similar to that without the additive during storage, whereas that with carrageenan and xanthan gum was higher than that without the additive. Hardness, chewiness and gumminess of the gels with the locust bean gum was higher than that without the additive during storage, whereas that with carrageenan and xanthan gum was lower than that without the additive. The rupture stress, rupture strain and rupture energy of the gels with carrageenan and xanthan gum was lower than that without the additive during storage, whereas that with the locust bean gum was similar to that without the additive. In the sensory evaluation, springiness and cohesiveness of the gels with carrageenan and xanthan gum were lower than those without the additive, whereas springiness, brittleness and hardness of the gels with the locust bean gum were higher than those without the additive. In addition, the overall acceptability of the gels with the locust bean gum improved. The above results showed that carrageenan and xanthan gum lowered the quality characteristics of the mungbean starch gel and the locust bean gum improved them. Thus, the addition of 0.5% locust bean gum is an appropriate method for improving the quality characteristics of mungbean starch gel.
The appearances and geometry structures of knitted fabrics have important effects on their functions as textile fabrics. Structural design of the woven fabric, prior to the manufacturing processes in the weaving mill, often leads to a similar predictable appearance in the final outcome with the corresponding weave design. The increase of the employment of elastic textile yarns in knitting fabrics for comfort stretch or outdoor sports wear knit products has, however, resulted in difficulties in predicting the final appearance of the knit structure design. Due to the stretchability and exceptional recovery behavior of the elastic yarns such as polyurethane elastomeric yarns, the appearance of the final product often differs from the initial knit design. At textile CAD program for preparing tricot knit designs has been employed in this study to predict the two dimensional appearance of the design. The similarities between the designs and corresponding knit products seem to be acceptable for the two-dimensional textile CAD program in this study. However, when elastomeric yarns are partially employed in the polyester filament tricot product, a considerable amount of departure from the design is apparent due to the constriction and/or deformation of property differences in the elastomeric yarns and polyester filament yarns. Therefore, another purpose of this study is to measure the departure of the final tricot product from the initial tricot design, especially in the case employing elastomeric yarns in the knit structure together with regular polyester filament yarns. For measuring the three-dimensional departure, a 3D scanning system has been used for the mesh reconstruction of the fabric specimen. Hopefully, the result from this study will be used as a guide to modify and improve the current textile CAD program proposed for the two-dimensional simulation of the tricot.
From 1988 to 1989, 8 strains of canine parvovirus-2 (CPV-2) were isolated from the fecal specimens from the dogs that were clinically diagnosed as canine parvoviral enteritis in the veterinary hospitals located in the regions of Taejon and Chungbuk province. Studios on biological and physicochemical properties for the isolates were carried out. The results obtained by experiments are summarized as follows. 1. Among 62 fecal samples collected from the dogs with enteric diseases, 24 (38.7%) showed the haemagglutinating activity against porcine erythrocyte, ranging from 16 to 16, 384 of HA titers. 2. When 8 fecal specimens with high HA titer over 1, 000 were inocultated into CRFX cells, intranuclear inclusion bodies were obseverd in all of eight specimens, of w)lick three specimens showed cytoplasmic inclusions concurrently with the intranuclear inclusion bodies. 3. In study on species-specificity of haemagglutinating activity of the isolates, TJ-89-1 and TJ-89-2, it was found that the isolates revealed the highest haemagglutinating activity with porcine erythrocytes, showing the relatively lower haemagglutination titers with the erythrocytes from cat and rabbit. None of erythrocytes from other animals reacted with the isolates. 4. By the cross-haemagglutination inhibition test of the Isolates with reference viruses and sera, the Isolates were evidently identified as the strains of canine parvovirus-2. 5. In Physicochemical property test, it was evident that the isolates were stable in, lipid solvent, pH and heat treatment at $56^{\circ}C$ for 30 min. and contain DNA genome. 6. When seven puppies were inoculated intraorally with the isolate at HA titer of 8, 192, all of the puppies showed the symptoms of anorexia, vomiting, diarrhea and died at the 5th to 10th days post inoculation(pi). The fecal samples from all of the puppies revealed significantly high HA titers afterward the 5th days pi. Body temperature and the number of total leucocytes were slightly increased at the early stage of infection. but extremely decreased at the stage of collapse. HI titers of the sera started to increase at the 2nd to 3rd days pi reaching 512 to 1, 024 at the 4th to 5th day pi.
Proceedings of the Korean Society of Crop Science Conference
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2017.06a
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pp.137-137
/
2017
Rice has important role as a primary food resource in especially the Asia, Korea, China, India, Indonesia and Japan. After development and increasingly using artificial chemical fertilizer, rice is getting high quality and quantity to satisfy ever-increasing people. On the other hand, the earth environment is more polluted each day. Nowadays consumers are looking for the organic crops or foods that were grown with eco-friendly method and in pure farmland. With the immergence of this trend, it is time to development environmentally-friendly agriculture. One of the methods is growing green manure crops in winter or spring on the fields. For this reasons, growing rye and Italian ryegrass are useful to use green manure to enhance rice production without chemical fertilizers and make the property of the soil eco-friendly. To know how improve the quality and quantity of rice with green manures, rye and Italian ryegrass, first the characteristics of green manure corps were measured. Dry matter yields of the rye and Italian ryegrass were 2.21 and $1.81t\;Ha^{-1}$. And the percentages of the dry matter were 28 and 32%. And, analyzed mineral components in rye and Italian ryegrass were nitrogen, organic matter, $P_2O_5$, CaO, $C_2O$ and MgO. Specially, the percentages of the organic matter and the CaO between rye and Italian ryegrass have difference appreciably. the height of the rice on the Italian ryegrass-fertilized field was the highest among the variant fields. The height of the rice on the non-fertilized field was the lowest. Yield of the Italian ryegrass-, rye- and non-fertilized rice are 805.2, 639.9 and $415.3kg\;10a^{-1}$. At the result, Italian ryegrass is the most effective green manure among the 3 treated-fertilized.
Lee, Chang Il;Kim, Eun Kyum;Park, Jong Sik;Lee, Yong-Joo
Geomechanics and Engineering
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v.15
no.5
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pp.1061-1070
/
2018
The main purpose of retaining wall methods for deep excavation is to keep the construction site safe from the earth pressure acting on the backfill during the construction period. Currently used retaining wall methods include the common strut method, anchor method, slurry wall method, and raker method. However, these methods have drawbacks such as reduced workspace and intrusion into private property, and thus, efforts are being made to improve them. The most advanced retaining wall method is the prestressed wale system, so far, in which a load corresponding to the earth pressure is applied to the wale by using the tension of a prestressed (PS) strand wire. This system affords advantages such as providing sufficient workspace by lengthening the strut interval and minimizing intrusion into private properties adjacent to the site. However, this system cannot control the tension of the PS strand wire, and thus, it cannot actively cope with changes in the earth pressure due to excavation. This study conducts a preliminary numerical analysis of the field applicability of the controllable prestressed wale system (CPWS) which can adjust the tension of the PS strand wire. For the analysis, back analysis was conducted through two-dimensional (2D) and three-dimensional (3D) numerical analyses based on the field measurement data of the typical strut method, and then, the field applicability of CPWS was examined by comparing the lateral deflection of the wall and adjacent ground surface settlements under the same conditions. In addition, the displacement and settlement of the wall were predicted through numerical analysis while the prestress force of CPWS was varied, and the structural stability was analysed through load tests on model specimens.
The woven fabric composed of nylon 6 filaments was treated with aqueous solutions (20, 30, 40, 50, 60%) of formic acid at 3$0^{\circ}C$ for 10 minutes under unrestrained condition, and the shrinkage behavior and some kinds of properties were examined. The shrinkages of the constituent yarns and fabric were increased with formic acid concentration, but they were lower than that of the original filaments because of fabric-structural factors. And the shrinkage of the warp was lower than that of the weft because of the residual stress from weaving process. By the restraint forces such as fabric-structural factors and residual stress, the constituent filaments were damaged partially at 60% of formic acid concentration and the degree of damage on the warp was greater than on the weft. And though the fabric count were increased overall, the spacing between the warps was decreased prior to the weft and eliminated nearly at 60% of formic acid concentration. The thickness, tensile strength, elongation, and handle value of fabric were increased overall with formic acid concentration excepting that the tensile strength for both the warp and weft directions and the elongation for the warp direction were decreased instead by the damage of yarns. But the crease recovery was decreased except the case of the weft direction at 60% of formic acid concentration.
Translationally controlled tumor protein (TCTP), also known as histamine releasing factor (HRF), is found abundantly in different eukaryotic cell types. The sequence homology of TCTP between different species is very high, belonging to the MSS4/DSS4 superfamily of proteins. TCTP is involved in both cell growth and human late allergy reaction, as well as having a calcium binding property; however, its primary biological functions remain to be clearly elucidated. In regard to many possible functions, the TCTP of Plasmodium falciparum (Pf) is known to bind with an antimalarial agent, artemisinin, which is activated by heme. It is assumed that the endoperoxide-bridge of artemisinin is opened up by heme to form a free radical, which then eventually alkylates, probably to the Cys14 of PfTCTP. Study of the docking of artemisinin with heme, and subsequently with PfTCTP, was carried out to verify the above hypothesis on the basis of structural interactions. The three dimensional (3D) structure of PfTCTP was built by homology modeling, using the NMR structure of the TCTP of Schizosaccharomyces pombe as a template. The quality of the model was examined based on its secondary structure and biological function, as well as with the use of structure evaluating programs. The interactions between artemisinin, heme and PfTCTP were then studied using the docking program, FlexiDock. The center of the peroxide bond of artemisinin and the Fe of heme were docked within a short distance of $2.6{\AA}$, implying the strong possibility of an interaction between the two molecules, as proposed. When the activated form of artemisinin was docked on the PfTCTP, the C4-radical of the drug faced towards the sulfur of Cys14 within a distance of $2.48{\AA}$, again suggesting the possibility of alkylation having occurred. These results confirm the proposed mechanism of the antimalarial effect of artemisinin, which will provide a reliable method for establishing the mechanism of its biological activity using a molecular modeling study.
Journal of the Korean Institute of Electrical and Electronic Material Engineers
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v.27
no.2
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pp.85-90
/
2014
Ag paste has been used in the front electrode of the Si-solar cell. It is composed by Ag powder, glass frit, binder, solvent and dispersant. The role of the binder and the solvent is to make a flow and a printing property. However, it was not enough to report the printing properties with the variation of binder in the controled viscosity. In this study, we selected 3 kinds of typical binder which were used as binder for the paste in the industry, such as Ethyl cellulose, Hydroxypropyl cellulose and Acrylic. Ag pastes using these were prepared, controled viscosity and printed on the SiNx coated Si wafer. In the 'A paste' used Acrylic binder, printed hight was highest and 'H paste' used Hydroxypropyl cellulose binder was lowest. Because 'H paste' was high viscosity due to the molecular weight, the solvent was added in the paste to control the viscosity. Therefore, the content of solid was lower in 'H paste'. The relative pattern width which is related to the spreading of paste was the best in the case of 'H paste' and 'EH paste' at $30^{\circ}C$. It is thought that the optimization of the relative pattern width is possible for a paste by the controling shear thinning phenomenon. In the case of 'A paste', though printing hight was best, the pattern width was dependant on the temperature.
Kim, Jinuk;Bak, Jeonggyu;Kang, Young-Seok;Cho, Jinsoo
The KSFM Journal of Fluid Machinery
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v.18
no.2
/
pp.60-66
/
2015
Conjugate heat transfer analysis was performed to investigate the flow and cooling performance of the high pressure turbine nozzle of gas turbine engine. The CHT code was verified by comparison between CFD results and experimental results of C3X vane. The combination of k-${\omega}$ based SST turbulence model and transition model was used to solve the flow and thermal field of the fluid zone and the material property of CMSX-4 was applied to the solid zone. The turbine nozzle has two internal cooling channels and each channel has a complex cooling configurations, such as the film cooling, jet impingement, pedestal and rib turbulator. The parabolic temperature profile was given to the inlet condition of the nozzle to simulate the combustor exit condition. The flow characteristics were analyzed by comparing with uncooled nozzle vane. The Mach number around the vane increased due to the increase of coolant mass flow flowed in the main flow passage. The maximum cooling effectiveness (91 %) at the vane surface is located in the middle of pressure side which is effected by the film cooling and the rib turbulrator. The region of the minimum cooling effectiveness (44.8 %) was positioned at the leading edge. And the results show that the TBC layer increases the average cooling effectiveness up to 18 %.
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