• Journal of Nutrition and Health
• /
• 제54권5호
• /
• pp.435-447
• /
• 2021

Purpose: Body adiposity is negatively correlated with hepatic iron status, and Korean pine nut oil (PNO) has been reported to reduce adiposity. Therefore, we aimed to study the effects of PNO on adiposity, hepatic mineral status, and the expression of genes and proteins involved in iron absorption. Methods: Five-week-old male C57BL/6 mice were fed a control diet containing 10% kcal from PNO (PC) or soybean oil (SBO; SC), or a high-fat diet (HFD) containing 35% kcal from lard and 10% kcal from PNO (PHFD) or SBO (SHFD). Hepatic iron, copper, and zinc content; and expression of genes and proteins related to iron absorption were measured. Results: HFD-fed mice had a higher white fat mass (2-fold; p < 0.001), lower hepatic iron content (25% lower; p < 0.001), and lower hepatic Hamp (p = 0.028) and duodenal Dcytb mRNA levels (p = 0.037) compared to the control diet-fed mice. Hepatic iron status was negatively correlated with body weight (r = -0.607, p < 0.001) and white fat mass (r = -0.745, p < 0.001). Although the PHFD group gained less body weight (18% less; p < 0.05) and white fat mass (18% less; p < 0.05) than the SHFD group, the hepatic iron status impaired by the HFD feeding did not improve. The expression of hepatic and duodenal ferroportin protein was not affected by the fat amount or the oil type. PNO-fed mice had significantly lower Slc11a2 (p = 0.022) and Slc40a1 expression (p = 0.027) compared to SBO-fed mice. However, the PC group had a higher Heph expression than the SC group (p < 0.05). The hepatic copper and zinc content did not differ between the four diet groups, but hepatic copper content adjusted by body weight was significantly lower in the HFD-fed mice compared to the control diet-fed mice. Conclusion: HFD-induced obesity decreased hepatic iron storage by affecting the regulation of genes related to iron absorption; however, the 18% less white fat mass in the PHFD group was not enough to improve the iron status compared to the SHFD group. The hepatic copper and zinc status was not altered by the fat amount or the oil type.

• 한국식품영양학회지
• /
• 제26권4호
• /
• pp.895-908
• /
• 2013

The purpose of this study is to examine female baby boomers' dietary habits and their attitudes together with their needs for future perspectives of dietary life. Our aim is to use these findings as a basic data when forecasting for food-related industries or policy making. A survey is being carried out for a total of 358 female baby boomers and analyzed by SPSS 12.0. The following is a summary of this study. The average age is 52.6 years old, most of them graduated from highschool (63.1%) and had a nuclear type of family (76.1%). Only 39.0% is composed of housewives, others had either full-time or part-time jobs. Self-assessment of stress is not so high and only 8.1% are dissatisfied with their lives. 38.2% are either overweight or obese in terms of BMI, and most of them are non-smokers (97.2%) or non-drinkers (63.0%). Their mean dietary habit scores are $70.6{\pm}11.8$, and the scores show significant relations with their education levels (p<0.01), monthly income (p<0.01), life satisfaction rates (p<0.001), stress levels (p<0.001), smoking habits (p<0.05), drinking habits (p<0.05), regular exercises (p<0.001) and regular health check-ups (p<0.05). The rate of skipping breakfast, lunch and dinner are 18.2%, 1.1%, 5.2% respectively. The main reason for skipping breakfast is the 'lack of time'. With regards to the frequency of grocery shopping, almost half of the subjects (55.7%) said '1~2 times per week' and bought mainly raw food sources such as vegetables, fruits, and meats. The majority of the subjects (91.3%) report that they cooked meals at homes, and took about 1 hour of time. The subjects also point out that cooking was a bothering task, and only 46.4% would prepare meals at home, while others would rather eat out or eat convenience foods. The main reasons for not wanting meal services in the elderly welfare facility are because they didn't want to live such places (48.4%) and the meals are tasteless (31.3%). As for delivery meal services, 60.1% are aware of it, and 39.9% would consider using it in the future. Factors to be considered when using the delivery meal service are sanitation (43.7%), nutrition (28.7%), taste (18.4%), price (6.3%), and brand name (2.9%). This study is expected to be used as useful information when developing food-related strategies for baby boomers in the future.

• Tuberculosis and Respiratory Diseases
• /
• 제71권2호
• /
• pp.114-119
• /
• 2011

Background: There is very limited data present on smoking cessation rates in outpatient departments of pulmonology. In this study, we aimed to investigate the effectiveness of a brief smoking cessation intervention program in an outpatient department of pulmonology and identify predictors of smoking cessation failure. Methods: After a brief recommendation of smoking cessation from pulmonologists, smokers willing to quit smoking were given individual counseling and supplement drugs. Fifty smokers were included in this study and baseline characteristics, smoking history and success rate were reviewed at 3 months. Results: The mean age of the patients was $58.3{\pm}14.6$ years and the total group of patients included 3 women. The rate of smoking cessation success was 74% at 3 months, and there were no differences in age, spirometric indexes and associated diseases between the smoking cessation success and failure group. The rate of supplement drug usage was not different in both groups either. However, body weight, mean number of cigarette usage per day and nicotine dependence scores in the failure group were significantly higher than in the success group. In multivariate analysis, body weight and mean number of cigarette usage per day were significant. Two smokers with a depressive disorder failed the smoking cessation. Conclusion: A smoking cessation intervention program in the outpatient department of pulmonology showed a favorable success rate. More intensive interventions are needed to unfavorable groups which include the obese and heavy smokers.

• 동아시아식생활학회지
• /
• 제17권1호
• /
• pp.27-42
• /
• 2007

The purpose of this study is to investigate the importance of well-being related to lifestyle choices such as food habits, food choices, life pattern, etc. The survey was conducted among college students using a questionnaire and a 5-point Likert score in Seoul City and Kyunggido Province during September 2005. The responses of 968 college students were analyzed by the SPSS program. The results were as follows. Most of the subjects were female(76.2%), and lived with their parents (85.6%). The average score of 'food habits', 'choosing food materials', 'purchasing' and 'life pattern' were $2.71{\pm}1.22,\;2.86{\pm}1.28,\;2.41{\pm}1.21,\;and\;2.97{\pm}1.31$ respectively in males and $3.01{\pm}1.20,\;3.00{\pm}1.32,\;2.55{\pm}1.20,and\;2.68{\pm}1.40$ in females, respectively. In regard to 'food habits', the scores were significantly affected by gender(p<0.001), smoking(p<0.05), alcohol consumption(p<0.05), exercise(p<0.001), weight satisfaction(p<0.001), method of weight control(p<0.001), use of nutritional supplement(p<0.05), attempts at weight control(p<0.001), regularity of breakfast(p<0.001), level of interest in well-being(p<0.001), and whether the individual tried a well-being item(p<0.001). In regarding to 'choosing food materials' the scores were significantly affected by gender(p<0.001), smoking(p<0.05), exercise(p<0.001), weight satisfaction(p<0.05), method of weight control(p<0.05), use of nutritional supplement(p<0.05), attempts at weight control(p<0.001), regularity of breakfast(p<0.001), level of interest in well-being(p<0.001) ), and whether the individual tried a well-being item(p<0.001). Out of the factors affecting 'purchasing', the association with BMI was remarkable. Students who were overweight, obese or underweight showed higher average scores than students of normal weight. The primary concerns and trial of well-being of college students were food and exercise. Therefore, the purchase of well-being goods is related to their weight control in college students. In regard to 'life pattern' the scores were significantly affected by exercise(p<0.01), use of computer(p<0.001), BMI(p<0.001), weight control(p<0.001), use of nutritional supplement(p<0.05), regularity of breakfast(p<0.001), level of interest in wellbeing(p<0.001), whether the individual tried a well-being item(p<0.001), and having taken lecture on well-being(p<0.05). Therefore nutrition education is needed for healthy eating habits of college students and it is necessary to develop a series of lectures to teach them about diet and exercise programs.

• 대한임상검사과학회지
• /
• 제51권3호
• /
• pp.277-285
• /
• 2019

비만과 혈관 경직도간에 역상관 관계가 보고되고 있으나, 고령자나 노인에서는 일관된 결과를 보이고 있지 않다. 이 연구에서는 건강한 노인을 대상으로 CAVI로 측정한 동맥 경직도와 BMI간의 연관성을 조사하였다. 이 연구는 2018년 7월부터 2019년 6월까지 경기지역 종합병원에서 건강검진을 시행한 65세 이상 건강한 노인을 629명을 대상으로 하였다. 대사증후군 진단은 US National Cholesterol Education Program(NCEP)의 Adult Treatment Panel (ATP) III의 기준에 따랐으며, NCEP-ATP III의 기준 중 허리둘레 및 비만기준은 WHO의 기준에 따랐다. 모든 연구 대상자는 생화학적 혈액검사 및 CAVI를 측정하였다. 남녀 모두에서 CAVI치는 정상체중군보다 비만군에서 낮았으며, 성별(P=0.047), 연령(P<0.001), BMI (P<0.001), 허리둘레(P=0.009)는 CAVI에 영향을 미치는 요인이었다. 또한 성별, 높은 혈압, 고혈당은 CAVI치의 독립적인 정적 예측인자이지만, 비만은 부적 예측인자로 나타나 CAVI와 BMI는 역상관 관계를 보였다. 결론적으로, 이 연구는 노인을 대상으로 CAVI와 BMI간에 역상관 관계를 나타내며, BMI로 측정한 비만은 CAVI의 부적 예측인자였다.

• Journal of Preventive Medicine and Public Health
• /
• 제38권1호
• /
• pp.101-106
• /
• 2005

Objectives : We conducted this study to examine the association between serum GGT levels within the normal range and the risk factors of cardiovascular diseases Methods : We examined the cross-sectional association between serum GGT and the systolic and diastolic blood pressure, fasting blood glucose, total cholesterol, triglyceride, high density lipoprotein cholesterol (HDLcholesterol), and uric acid among 975 subjects that participated in the health examination of a university hospital located in Daegu city. All the patients' GGT levels were within the normal range. Results : After adjustment were made for age, body mass index (BMI), smoking status, drinking frequency, exercise frequency and coffee intake, the serum GGT level was positively associated with fasting blood glucose (p<0.01), total cholesterol (p<0.01), and triglyceride (p<0.01) in men, and it was positively associated with fasting blood glucose (p<0.01), total cholesterol (p<0.05), triglyceride (p<0.01), and uric acid (p<0.01) in women. The associations were not significantly different depending on the status of alcohol drinking or obesity, except for the associations of serum GGT with diastolic blood pressure (P for interaction=0.04) and uric acid (P for interaction=0.04) between the lean and obese subjects. Conclusions : Serum GGT levels within the normal range were positively associated with fasting blood glucose, triglyceride and uric acid in most subgroups irrespective of the drinking or obesity status. These results suggest that GGT has important clinical implications as being more than just a marker of alcohol consumption and hepatobiliary disease.

• Nutrition Research and Practice
• /
• 제6권1호
• /
• pp.68-77
• /
• 2012

Flavan-3-ols are a subclass of flavonoids found in a variety of foods including teas. The effects of flavan-3-ols on the risk of metabolic syndrome (MetS) have been investigated, generally focusing on tea catechins or individual flavan-3-ol rich foods, but there is little information on dietary flavan-3-ols intake and risk of MetS in population-based studies. In this cross-sectional study, we examined the association between dietary flavan-3-ols intake and the risk of MetS in Korean adults. Subjects comprised 1,827 men and 2,918 women aged 20-69 years whose data was included in the 2008 Korean National Health and Nutrition Examination Survey. This survey was conducted between January 2008 and December 2008. Total flavan-3-ols intakes were calculated from 24-hour dietary recalls using a flavonoids database. Thirty percent of the male subjects and 24% of the female subjects were reported as having MetS. In the female subjects, flavan3-ols intake was inversely associated with the risk of MetS after adjusting for potential confounders (5th vs. 1st quintile, OR=0.64, 95% CI=0.45-0.91, P for trend=0.384). The main food source of flavan-3-ols was green tea followed by apples and grapes. Among MetS components, flavan-3-ols intake was inversely associated with the risk of high blood pressure after adjusting for potential confounders (5th vs. 1st quintile, OR=0.64, 95% CI=0.45-0.90, P for trend=0.005). No significant association between flavan-3-ols intake and risk of MetS was found in the male subjects. After stratified analysis by obesity (BMI ${\geq}$ 25 or BMI < 25), however, flavan3-ols intake was inversely related to the risk of hypertension in non-obese men. These results suggest that dietary flavan-3-ols intake may have beneficial effects on MetS risk by reducing the risk of hypertension. The effects of flavan-3-ols intake dependent on obesity need further investigation.

• 치위생과학회지
• /
• 제15권3호
• /
• pp.333-339
• /
• 2015

본 연구는 성인의 치아우식증에 영향을 미치는 관련요인을 알아보고자 제6기 1차년도(2013년) 국민건강영양조사중 건강설문 검진조사, 영양조사를 완료한 10,113명 중 만 19세 이상의 성인과 영구치우식 유병자 여부 카테코리에 대한 정보가 갖춰진 4,843명을 최종 분석대상자로 복합표본분석을 실시하였으며, 연구결과는 다음과 같다. 사회 경제적 특성에 따른 치아우식증 유병률은 성별에서 남자가 여자보다 높았으며(p<0.001), 연령별로는 30대, 20대, 40대, 60대 이상, 50대 순으로 나타났다(p<0.05). 교육수준에 따라서는 고졸, 중졸, 대졸 이상 순으로 나타났고(p<0.05), 월 소득수준은 '하'인 경우 가장 높게 나타났다(p<0.001). 건강관련 생활양식에 따른 치아우식증 유병률은 흡연자가 비흡연자보다 높게 나타났으며(p<0.001), 비만의 경우 정상보다 다소 높았으며(p<0.05), 구강검진을 받지 않은 경우가 받는 경우보다 높았다(p<0.001). 일일 칫솔질 횟수가 증가할수록(p<0.05), 치실, 치간칫솔을 사용하는 경우 치아우식증 유병률이 감소하는 것으로 유의하게 나타났다. 치아우식증 여부를 종속변수로 로지스틱 회귀분석을 실시한 결과 치아우식증에 영향을 미치는 변수로는 성별, 연령, 소득수준, 흡연, 구강검진, 치실사용 등으로 나타났다. 이상의 결과를 종합해 보면 한국 성인의 사회 경제적 요인 및 생활양식은 치아우식증에 영향을 미치는 것으로 확인되었으며, 성인의 치아우식증 예방 및 구강건강을 향상시키기 위해서는 건강한 생활습관을 실천할 수 있는 구강건강교육 및 실천 프로그램의 개발이 필요하다고 생각되었다.

• 한국산학기술학회논문지
• /
• 제19권12호
• /
• pp.584-591
• /
• 2018

본 연구는 우리나라 100세 이상 고령자의 인지기능장애 수준을 알아보고 그의 관련요인을 규명해 보고자 시도하였다. 연구대상은 2016년부터 2017년까지의 기간 동안에 국민건강보험공단에서 시행하는 건강검진 및 장기요양 인정조사를 받은 주민등록상의 100세 이상 고령자 268명(남성 132명, 여성 136명)으로 하였다. 연구결과, 조사대상 100세 이상 고령자의 인지기능장애수준은 남성보다 여성에서(p=0.000), 혼자 산다는 군보다 배우자나 자녀와 함께 산다는 군에서(p=0.019), 가정의 경제 상태가 낮을수록(p=0.001), 비만도가 낮을수록(p=0.000), 비흡연군보다 흡연군에서(p=0.000), 비음주군보다 음주군에서(p=0.013), 규칙적인 운동을 한다는 군보다 하지 않는다는 군에서(p=0.020)에서 유의하게 낮았다. 조사대상 100세 이상 고령자의 확정적 인지기능장애가 나타날 위험비는 남성보다 여성(ORs=9.85, 95% CI=2.88~33.59)에서 유의하게 증가하였고, 저체중군보다 비만군(ORs=0.25, 95% CI=0.07~0.86)에서, 흡연군보다 비흡연군(ORs=0.30, 95% CI=0.10~0.83)에서 유의하게 감소하였다. 조사대상 100세 이상 고령자의 인지기능장애에 영향을 미치는 요인으로는 성, 거주상태, 경제상태, BMI, 흡연상태가 유의한 변수로 선정되었다. 이상과 같은 연구결과를 보면, 조사대상 100세 이상 고령자의 인지기능장애 수준은 여러 인구사회학적 및 건강관련행위특성 변수에 따라 유의한 차이를 보이고 있었다. 특히 흡연, 음주 및 규칙적인 운동 등과 같은 건강관련행위특성이 좋지 않은 군에서 인지기능 수준이 저하됨을 시사하고 있다.

• 농촌의학ㆍ지역보건
• /
• 제25권1호
• /
• pp.29-49
• /
• 2000

충남 천안시의 30세 이상 인구에서 표본추출된 7,030명 중 조사된 5,372명에 대하여 고혈압의 유병률을 파악하고, 이들 중 의료기관에서 고혈압으로 진단을 받은 후의 치료순응과 행태의 차이를 파악하기 위하여 1998년 10월 16일부터 12월 19일까지 조사한 결과는 다음과 같다. 1. JNC VI의 고혈압 1도 기준에 의한 고혈압 유병률은 남자 49.8%, 여자 38.8%로 남자가 높았으며, 연령별 고혈압 유병률은 남녀 모두 50대까지는 연령이 증가함에 따라 증가하다가 그 이후는 완만하게 증가하는 양상을 보였다. 2. 교육수준별 고혈압 유병률은 남자의 경우 학력에 따라 차이가 크지 않았으나, 여자의 경우 초등학교 이하 49.8%, 중졸 37.6%, 고졸 24.9%, 대졸 19.6%로 학력이 높아질수록 낮아지는 경향을 보였다. 가구당 월평균수입별 고혈압 유병률은 수입에 관계없이 일정하였으며, 직업별 고혈압 유병률은 무직에서 전문·관리직에 비하여 상대적으로 높았다. 비만도별 고혈압 유병률은 남녀 모두 과체중에서 세장형, 정상체중 군에 비하여 높았다(p<0.01). 3. 고혈압 가족력이 있는 군의 고혈압 유병률은 58.5%로 가족력이 없는 군의 46.7% 보다 높았으나(p<0.01), 여자는 가족력이 있는 군이 38.5%, 없는 군이 38.9%로 비슷하였다. 콜레스테롤 수치별 고혈압 유병률은 콜레스테롤의 수치가 240 mg/dl 이상에서 남자 64.0%, 여자 52.4%로 240 mg/dl 미만의 남자 48.9%, 여자 37.6%보다 높았다(p<0.01). 혈당의 고혈압 유병률은 남녀 모두 혈당치가 증가할수록 높아졌고, 200 mg/dl 이상부터는 크게 높아졌다. 4. 의료기관에서 고혈압으로 진단받은 사람 중 치료순응군은 61.1%, 치료비순응군은 38.9%이었으며, 현재의 혈압분포는 고혈압이 치료순응군에서 79.8%, 치료비순응군 81.1%로 두 군이 비슷하였다. 5. 연령별 치료순응도는 남녀 모두 치료순응군이 치료비순응군에 비하여 연령이 많았고, 학력은 치료비순응군에서 높았다(p<0.01). 직업별 치료순응도는 남자의 경우 치료순응군은 무직에서 높았으나, 치료비순응군은 단순 노무, 사무 기술직에서 높았으며(p<0.01), 여자는 직업에 따라 치료순응도의 차이가 없었다. 6. 가구당 월수입별 치료순응도는 남자의 경우 치료비순응군이 치료순응군에 비하여 수입이 높았으며(p<0.01), 여자는 차이가 없었고, 가족력별 치료순응도는 남녀 모두 차이가 없었다. 7. 치료순응과 관련된 행태 중 운동의 규칙성은 남자의 경우 치료순응군이 83.7%, 치료비순응군이 62.2%로 치료순응군에서 높았으나(p<0.05), 여자는 차이가 없었다. 주관적 건강 상태가 나쁘다고 생각하는 경우가 남녀 모두 치료순응군에서 높았으며(p<0.01), 흡연을 하는 사람과 흡연랑은 남자의 경우 치료비순응군에서 높았으며(p<0.01), 여자는 두 군간에 차이가 없었다. 8. 음주를 하는 사람은 남녀 모두 치료비순응군에서 높았으며(p<0.05), 음주횟수는 두 군간에 차이가 없었으며, 체질량지수, 체중측정의 규칙성, 체중조절방법, 운동여부, 육류섭취와 식염섭취, 혈중 콜레스테롤과 혈당은 치료순응도과 관계가 없었다. 9. 치료를 위한 비약물요법 실천은 남자의 경우 치료순응군이 13.2%, 치료비수응군이 2.5%로 치료순응군이 높았으며(p<0.01), 여자도 치료순응군 10.6%, 치료비순응군 0.8%로 치료순응군에서 높았다. 결론적으로 고혈압 유병률이 매우 높아 순환기계질환에 미칠 영향이 매우 클 것이며, 치료순응도에 따른 치료효과를 높이고, 건강증진을 위하여 건강행태변화를 유도하여야 할 것이다. 그러므로 이를 위한 보건교육과 홍보 등의 확대와 지속적인 관리대책을 세우는 것이 필요하다고 본다.