• 제목/요약/키워드: the model of the suffering

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A novel excisional wound pain model for evaluation of analgesics in rats

  • Parra, Sergio;Thanawala, Vaidehi J.;Rege, Ajay;Giles, Heather
    • The Korean Journal of Pain
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    • 제34권2호
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    • pp.165-175
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    • 2021
  • Background: Management of pain from open wounds is a growing unmet healthcare need. However, the models available to study pain from wounds or to develop analgesics for the patients suffering from them have primarily relied on incisional models. Here, we present the first characterized and validated model of open wound pain. Methods: Unilateral full-skin excisional punch biopsy wounds on rat hind paws were evaluated for evoked pain using withdrawal responses to mechanical and thermal stimulation, and spontaneous pain was measured using hind paw weight distribution and guarding behavior. Evaluations were done before wounding (baseline) and 2-96 hours post-wounding. The model was validated by testing the effects of buprenorphine and carprofen. Results: Pain responses to all tests increased within 2 hours post-wounding and were sustained for at least 4 days. Buprenorphine caused a reversal of all four pain responses at 1 and 4 hours post-treatment compared to 0.9% saline (P < 0.001). Carprofen decreased the pain response to thermal stimulation at 1 (P ≤ 0.049) and 4 hours (P < 0.011) post-treatment compared to 0.9% saline, but not to mechanical stimulation. Conclusions: This is the first well-characterized and validated model of pain from open wounds and will allow study of the pathophysiology of pain in open wounds and the development of wound-specific analgesics.

Soil Loss Vulnerability Assessment in the Mekong River Basin

  • Thuy, Hoang Thu;Lee, Giha
    • 한국지반환경공학회 논문집
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    • 제18권1호
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    • pp.37-47
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    • 2017
  • The Mekong River plays an extremely important role in Southeast Asia. Flowing through six countries, including China, Myanmar, Thailand, Laos PDR, Cambodia, and Vietnam, it is a site of great biological and ecological diversity and the habitat of numerous species of fish. It also supports a very large population that lives along the river basin. Therefore, much attention has been focused on the giant Mekong River Basin, particularly, its soil erosion and sedimentation problems. In fact, many methods have been used to calculate and simulate these problems. However, in the case of the Mekong River Basin, the available data is limited because of the extreme size of the area (about $795,000km^2$) and lack of equipment systems in the countries through which the Mekong River flows. In this study, we applied the Universal Soil Loss Equation (USLE) model in a GIS (Geographic Information System) framework to calculate the amount of soil erosion and sediment load during the selected period, from 1951 to 2007. The result points out dangerous areas, such as the Upper Mekong River Basin and 3S Basin (containing the Sekong, Sesan, and Srepok Rivers) that are suffering the serious consequences of soil erosion problems. Moreover, the present model is also useful for supporting river basin management in the implementation of sustainable management practices in the Mekong River Basin and other basins.

고속철도 축소모형의 환경소음 예측을 위한 소음원 연구 (A Study of Sound Source to predict Environment Noise in High Speed Train : Scaled model)

  • 김태민;한재현;김정태
    • 한국철도학회:학술대회논문집
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    • 한국철도학회 2011년도 춘계학술대회 논문집
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    • pp.1342-1351
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    • 2011
  • Nowadays rolling stock has become a fast and convenient transportation and increased in its demands. But the improvement of speed has result in increase of aerodynamic noise and therefore residential districts near by the railroad are now constantly suffering from the racket. Thus the study regarding rolling stock's environmental noise measurement and appraisal has become important. The case of environmental noise, there are no changes of tone so prediction can be made by reducing areas around the railway. This is part of the study which estimates the noise around the railway using scaled model, and the source of the noise has been researched on. The scaled model of rolling stock will have to be able to make high frequency and it needs to be spread out in a short amount of time. When popping a balloon or firing a gun fits its condition and this study analyzed the characteristics of these two different noises. Measurement was held on a wide vacant lot and the reflection effect of the ground is additionally examined. It is judged to be used in the future when predicting the environmental noise of railway vehicles.

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Assessment of Sediment Yield according to Observed Dataset

  • Lee, Sangeun;Kang, Sanghyeok
    • 한국환경과학회지
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    • 제25권10호
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    • pp.1433-1444
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    • 2016
  • South Korea is a maritime nation, surrounded by water on three sides; hence, it is important to preserve in a sustainable manner. Most areas, especially those bordering the East Sea, have been suffering from severe coastal erosion. Information on the sediment yield of a river basin is an important requirement for water resources development and management. In Korea, data on suspended sediment yield are limited owing to a lack of logistic support for systematic sediment sampling activities. This paper presents an integrated approach to estimate the sediment yield for ungauged coastal basins by using a soil erosion model and a sediment delivery rate model in a geographic information system (GIS)-based platform. For applying the sediment yield model, a basin specific parameter was validated on the basis of field data, that, ranging from 0.6 to 1.2 for the 19 gauging stations. The calculated specific sediment yield ranged from 17 to $181t/km^2.yr$ in the various basin sizes of Korea. We obtained reasonable sediment yield values when comparing the measured data trends around the world with those in Korean basins.

자조모임을 통한 자살유가족의 '고통 이겨냄' 과정: SPACE 모델 (Experience of 'overcoming the pain of family loss of suicide' through suicide bereavement support group: SPACE experiential model of family survivors)

  • 서청희;박지영;백민정;김미숙
    • 한국가족관계학회지
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    • 제22권3호
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    • pp.73-101
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    • 2017
  • Objectives: This study is to understand the experiences of overcoming pain of loss of family survivors in Suicide Bereavement Support Group(SBSG). Method: Experiential data was collected by in-depth interview(FGI, individual) to 10 family survivors(over 19) who having an experience participating in SBSG over 5months and analyzed using qualitative methodology. Results: We drew the result that 'SPACE model' which structuralize by 5 stages of suicide survivors' experience of SBSG of time path. SPACE model configured as follow: Stage1, Space in vacuum, the time to feel a sense of overwhelming feeling like pain, fear, alienation after loss of suicide, Stage2, Probing, when to find informations and resources to help survivors themselves, Stage3, Acclimation, having experiences empathy and healing as in SBSG, Stage4, Composure, accepting SBSG meaning as a part of their lives, loss of my family by suicide, and the beginning of bereavement, Stage5, Endurance, overcoming suffering through SBSG and try to help other survivors. Conclusions: SBSG is the opportunity for family survivors to overcome the pains from loss of suicide, shock, anger, grief, etc., and to empower them to help other suicide survivors.

신경망을 이용한 HSLA 강의 고온 유동응력 예측 및 통계방법과의 비교 (A Comparative Study of Material Flow Stress Modeling by Artificial Neural Networks and Statistical Methods)

  • 천명식;이준정
    • 대한기계학회논문집A
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    • 제21권5호
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    • pp.828-834
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    • 1997
  • The knowledge of material stress-strain behavior is an essential requirement for design and analysis of deformation processes. Empirical stress-strain relationship and constitutive equations describing material behavior during deformation are being widely used, despite suffering some drawbacks in terms of ease of development, accuracy and speed. In the present study, back-propagation neural networks are used to model and predict the flow stresses of a HSLA steel under conditions of constant strain, strain rate and temperature. The performance of the network model is comparedto those of statistical models on rate equations. Well-trained network model provides fast and accurate results, making it superior to statistical models.

발산거리 기반의 신경망에 의한 가우시안 확률 밀도 함수의 군집화 (Guassian pdfs Clustering Using a Divergence Measure-based Neural Network)

  • 박동철;권오현
    • 한국통신학회논문지
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    • 제29권5C호
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    • pp.627-631
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    • 2004
  • 음성인식 모델상의 GPDFs(Gaussian Probability Density Functions)을 효율적으로 군집화 할 수 있는 알고리즘이 제안되었다. 제안된 알고리즘은 데이터 사이의 거리 척도로 발산 거리를 사용하는 새로운 형태의 CNN(Centroid Neural Network)으로, 제한된 자원을 가지는 H/W환경의 음성인식에서 메모리 사용량을 축소하는 응용에 대한 실험 결과, 음성인식 모델인 CDHMM(Continuous Density Hidden Markov Model)에서 기존의 Dk-means(Divergence-based k-means)알고리즘을 이용한 방법과 비교하여 인식 성능의 유지와 함께 약 31.3%의 GPDFs를 더 축소할 수 있었고, 군집화 알고리즘을 적용하지 자은 전체 GPDFs를 사용한 경우와 비교해서 인식 성능의 유지와 함께 약 61.8%의 GPDFs를 압축할 수 있었으며, SNR 10㏈ 잡음 데이터에 대한 성능평가에서도 인식 성능이 유지될 수 있었다.

피부건조증 환자에 대한 아로마오일 사용시 스킨 pH.소양증 변화 (The Effects of Aromatherapy on Skin pH and Pruritis in Patients with Xerosis Cutis)

  • 김은정;유왕근
    • 대한예방한의학회지
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    • 제8권2호
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    • pp.55-63
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    • 2004
  • Objectives : This study was designed to identify the possibility of aroma oils as the complementary medical goods specially for the effects of aromatheraphy on xerosis cutis. Materials and Methods : The participants were 23 adult patients and all participants of this study use aroma oils which is known to effect on xerosis cutis. The subjects consist of voluntary patients with xerosis cutis in Seong-So Hospital in Andong Kyoungbuk, Korea. From April 1st to April 30th, 2004 for 4 weeks, the subjects massaged aroma oils on itching parts or the whole body. Aroma oils were Lavender, Losemary, Jasmine and blended drop by drop per 10ml jojoba oil which used a carrier oil. Skin pH was measured with a skin pH meter(Model : HI98110, Se-Chang instruments, made in Portuga. After 4weeks using aroma oils, the participants answered questions about the feeling of satisfaction with aroma oils. Results : Changes in the physiological indices. The mean deviation of skin pH was $5.58{\pm}0.47$ points before using aroma oils and $5.53{\pm}0.45$ points after 2 weeks, no statistical significance was found(p=0.221). MD was $5.36{\pm}0.41$ points after 4 weeks using aroma oils, which was statistically significant decrease of 0.22 points(p=0.001) Changes on the Pruritus Score Scale. A modified scale of the Pruritus Score Scale(Duo, 1987) was used to measure the severity, location, frequency, and the inconveniences of daily life due to prurius. The maximum scale of severity was 4 points, the full marks of location was 2 points, the full marks of frequency was 3 points, the full marks of inconveniences of daily life due to pruritus was 3 points. The scores ranged from 0 to 12, with 12 indicating the most severe pruritus. There was no statistical difference in severity and frequency score at 4 weeks later(severity p=0.097, frequency p=0.633). A statistically significant difference was found in the score of location and the inconveniences of daily life due to pruritus(each p=0.003). Conclusion : Generally speaking, the patient suffering from renal itch is the higher than normal in skin pH levels. that means to show alkaline condition of skin surface. In some case in this study, skin pH levels was rather lower than normal levels when measured actually patients suffering from renal itch by skin pH meter. But in this study post-test skin pH levels decreased, showing the contribution of aromathrapy to acidic condition of skin surface in suffering from renal itch. It seems to be some help to cure a pruritus and also have no ill effects on aroma oils.

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Model Development of Illness Perception and Consequences in Breast Cancer Patients

  • Hoseini, L;Kashani, F Lotfi;Akbari, S;Akbari, ME;Mehr, S Sarafraz
    • Asian Pacific Journal of Cancer Prevention
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    • 제17권sup3호
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    • pp.185-190
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    • 2016
  • Breast cancer is the first or second malignancy among women worldwide. Illness perception (IP) and quality of life (QoL) are major issues considering breast cancer management. An attempt was here made to inspect the predictive variables influencing IP and their impact on QoL in cancer patients. The key predictors adapted from previous studies including life satisfaction, perceived social support, self-esteem, hope, optimism, and spiritual well being were taken into account. Our sample included 200 female volunteers suffering from breast cancer applying exclusion criteria. The data were collected using various questionnaires and statistically analyzed by means of path analysis and structural equation modeling. The results revealed that of the six predictors, spiritual well being and social support had direct effects on QoL and IP. The only path with significant indirect correlation with IP was social support. Spiritual well being had the second significant direct effect on IP. Self-esteem occupied the third rank in direct effects on both QoL and IP. In conclusion, here in Iran and most likely in other strongly religious communities, spiritual intervention is an effective strategy to raise QoL. Also social support helps women suffering from breast cancer to experience better conception and coping strategies.

구타, 성폭력, 이혼을 중심으로 본 여성건강 문제에 관한 고찰 (The Study on Woman's Health Problem in the View of Battering, Sexual Violence and Divorce)

  • 최의순;고명숙;이규은;길숙영
    • 여성건강간호학회지
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    • 제2권1호
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    • pp.106-124
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    • 1996
  • This paper reviews battering, sexual violence and divorce experienced among women. There three problems have negative influence on health status in women and are further developed to social problems such as family dissolution. The victims of the problems may manifest physical injury, emotional difficulties and social withdrawl, while their children may show problems caused by lack of parental caring and by resembling abusive behaviors of their parents. Hence, nurses need to pay attention to batting, sexual violence, and divorce and to develop relevant nursing interventions for them. Some strategies of dealing with those problems are presented in the following. First, we have to eliminate sexism prevailing in out society. Our society is assigning inequal and asymmetrical gender role. Mass media should inspire equality between genders and show a healthy model of family and community. Second, social system and laws should be changed through collective efforts. Those living conditions of women cannot be changed by the effort of women themselves only. We all need to work for establishing and changing the law, so that those women in suffering can obtain immediate and adequate protection. Third, social support system of consulting and referring women's problems should be established. Such support system as hot line, shelter and counseling clinics would help women in crisis. Fourth, job training and arrangement should be available to women who are divorced. Fifth, there should be self-help group for those women in suffering. Self-help group would help those women in sharing their problems and feelings and in establishing coping strategies. Nurses, as the largest group among health professionals, are sensitive and respond to health needs of clients and have an effect on managing women's health. However, we nurses have not been ready for dealing with problems of women, although most of us are women. we not need to change our perspective of women's health problems from a traditional medical perspective to feministic one. Accordingly, nurses need to develop realistic way of caring those women in suffering and to assist them in making decisions for their lives by themselves.

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