• Clinical and Experimental Reproductive Medicine
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• 제44권4호
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• pp.232-238
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• 2017

Objective: To determine whether reducing the cetrorelix dose in the antagonist protocol to 0.125 mg had any deleterious effects on follicular development, the number and quality of retrieved oocytes, or the number of embryos, and to characterize its effects on the affordability of assisted reproductive technology. Methods: This randomized controlled study was conducted at the Fertility Unit of Tanta Educational Hospital of Tanta University, the Egyptian Consultants' Fertility Center, and the Qurrat Aien Fertility Center, from January 1 to June 30, 2017. Patients' demographic data, stimulation protocol, costs, pregnancy rate, and complications were recorded. Patients were randomly allocated into two groups: group I (n = 61) received 0.125 mg of cetrorelix (the study group), and group II (n = 62) received 0.25 mg of cetrorelix (the control group). Results: The demographic data were comparable regarding age, parity, duration of infertility, and body mass index. The dose of recombinant follicle-stimulating hormone units required was $2,350.43{\pm}150.76$ IU in group I and $2,366.25{\pm}140.34$ IU in group II, which was not a significant difference (p= 0.548). The duration of stimulation, number of retrieved oocytes, and number of developed embryos were not significantly different between the groups. The clinical and ongoing pregnancy rates likewise did not significantly differ. The cost of intracytoplasmic sperm injection per cycle was significantly lower in group I than in group II (US $ $494.66{\pm}4.079$ vs. US $ $649.677{\pm}43.637$). Conclusion: Reduction of the cetrorelix dose in the antagonist protocol was not associated with any significant difference either in the number of oocytes retrieved or in the pregnancy rate. Moreover, it was more economically feasible for patients in a low-resource country.

• 한국인구학
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• 제29권1호
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• pp.241-268
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• 2006

본 연구는 출산율이 세계 최저수준으로 낮아진 한국사회의 적정인구를 사회복지적 관점에서 논의한다. 이는 인구규모의 급격한 감소와 인구구조외 불균형이 예측되어 결과적으로 국가발전에 부정적인 영향을 줄 것으로 전망되기 때문이다. 사회복지적 측면에서의 적정인구는 1인당 복지수준 또는 사회전체의 복지수준, 곧 사회적 후생(social welfare)의 크기 또는 복지성장률이 극대화되는 지점이다. 적정 인구구조는 전체인구대비 노인인구 약 $15{\sim}17%$, 생산인구 약 $64{\sim}69%$, 그리고 고령화지수 약 $72{\sim}104$ 수준이다. 또한 현재의 인구규모 및 인구구조를 감안한 한국의 적정 인구규모는 약 $4,850{\sim}4,950$만 명인 것으로 나타났다. 따라서 저출산의 원인제거로 출산율을 회복하여야 함과 동시에 외국인력을 유입할 수 있는 준비를 갖추어야 할 것이다. 아울러 아동들이 좋은 환경에서 성장할 수 있도록 노력하고 여성과 노인이 노동시장에 참여할 수 있는 조건을 제공하여야 할 필요가 있다.

• Clinical and Experimental Reproductive Medicine
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• 제43권1호
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• pp.26-30
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• 2016

Objective: We aimed to investigate the prevalence of erectile dysfunction (ED) and the usage of phosphodiesterase type 5 (PDE5) inhibitors for ED treatment in infertile couples. Methods: A total of 260 male partners in couples reporting infertility lasting at least 1 year were included in this study. In addition to an evaluation of infertility, all participants completed the International Index of Erectile Function (IIEF)-5 questionnaire to evaluate their sexual function. The participants were asked about their use of PDE5 inhibitors while trying to conceive during their partner's ovulatory period and about their concerns regarding the risks of PDE5 inhibitor use to any eventual pregnancy and/or the fetus. Results: Based on the IIEF-5 questionnaire, 41.5% of the participants (108/260) were classified as having mild ED (an IIEF-5 score of 17-21), while 10.4% of the participants (27/260) had greater than mild ED (an IIEF-5 score of 16 or less). The majority (74.2%, 193/260) of male partners of infertile couples had a negative perception of the safety of using a PDE5 inhibitor while trying to conceive. Only 11.1% of men (15/135) with ED in infertile couples had used a PDE5 inhibitor when attempting conception. Conclusion: ED was found to be common in the male partners of infertile couples, but the use of PDE5 inhibitors among these men was found to be very low. The majority of male partners were concerned about the risks of using PDE5 inhibitors when attempting to conceive. Appropriate counseling about this topic and treatment when necessary would likely be beneficial to infertile couples in which the male partner has ED.

• 한국인구학
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• 제21권1호
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• pp.184-228
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• 1998

한국에서는 가부장제도를 기초로 한 가족제도의 영향으로 심한 남아선호현상이 계속되고 있으며 또한 출산력은 최근 20여 년 간 급격히 저하되고 있다. 연구사례에 의하면, 한국은 남아선호경향이 세계 여러 나라 중 그 정도가 가장 심한 편이며, 출산력 저하속도 또한 어느 국가보다 빠르게 성취되었음을 보여준다. 이 논문에서는 잔존하고 있는 남아선호태도가 출산력 저하과정에서 출산행태를 통한 가족형성 과정과 영아 및 유아사망력에 어떤 영향을 끼치고 있는지 살펴본다. 한국을 비롯한 남아선호현상이 심한 나라에서는 출산행태가 남아선호 현상을 크게 반영하며 여아의 영아 및 유아 사망력이 남아보다 높다는 것은 이미 여러 연구 결과가 입증해주고 있다. 이 논문에서 중점적으로 살펴보고자 하는 점은 남아선호, 출산행태, 영아 및 유아 사망력 세 분야가 급격한 출산력저하 과정에서 어떤 상호 관계를 가지는지 살펴보는 것이다. 먼저, 동아시아와 남아시아의 남아선호 현상이 심한 나라의 기존 연구결과에 의해 남아선호 현상이 출산행태에 미치는 영향이 출산력 정도에 따라 어떻게 변하는가를 보고, 이어서 한국 조사자료(1991년 전국 출산력 및 가족보건실태조사)를 분석하여 출산력저하 과정에서의 남아선호 현상이 출산행태에 미치는 영향을 심층분석한다. 또 출산행태 자체가 영아 및 유아 사망력에 큰 영향을 준다는 점을 고려하여 남아선호 현상과 출산행태의 상호관계가 남, 여아의 사망력 차이를 간접적으로 설명한다는 가정하에 그 차이정도를 검토한다. 동아시아와 남아시아의 출산행태에 의하면, 현존자녀 중 아들이 없는 경우는 아들이 있는 경우보다 추가자녀를 가질 확률이 훨씬 높으며, 그 확률의 비교차(relative risk)는 출산력 수준이 낮을수록 더 큰 경향이다. 다시 말하면, 출산력저하는 남아선호 현상과 출산행태의 상호관계를 더욱 악화시키는 결과는 보여준다. 합계출산률이 3.3이던 1974년 이전에는 아들이 없는 사람에 비해 아들이 있는 사람은 40% 적게 셋째 아이를 가졌으며, 합계출산률이 1.8이던 1980-84년에는 아들이 없는 사람에 비해 있는 사람이 83% 적게 셋째아이를 가졌음이 추정되었다. 둘째-넷째 아이 중 "아들을 보기 위해서 원하는 아이보다 더 낳은 아이"는 1975년 이전에는 4% 정도였으나 1980-84년에는 13%나 되는 것으로 추정되었다. 남아선호 현상은 영아 및 유아 사망력에도 영향을 주고 있다. 한국의 영아사망력(0세)은 남자가 여자보다 조금 높지만, 유아 사망력(1-4세)은 여자가 남자보다 높은 것으로 추정되어 있다. 출산행태, 특히 출산간격은 영아 및 유아 사망력에 큰 영향을 준다는 점은 잘 알려진 사실이다. 한국에서도 자신의 출생 후 24개월 이내에 동생이 태어난 아이는 그렇지 아니한 아이에 비하여 5세 이하 사망력이 2.7배 이상 높게 추정된다. 또한 1971-85년 출생한 아이 중 남아선호와 출산행태간 관계의 결과로 여자아이는 24.1%가 24개월 이내에 동생이 태어난 데 비하여, 남자아이는 18.0%가 24개월 이내에 동생이 태어난 것으로 나타났다. 이러한 차이는 여자아이의 5세 이하 사망률이 남자아이보다 6% 높은 결과를 야기한다. 일반적으로 낮아진 영아 및 유아 사망력에도 불구하고 한국의 여자아이들이 남자보다 유아사망력을 경험하며 그 요인의 하나가 남아선호에서 비롯된 출산행태 때문이라는 것은 주목할 만한 점이다.목할 만한 점이다.

• 한국수정란이식학회지
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• 제28권2호
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• pp.87-93
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• 2013

The efficiency of artificial insemination (AI) for horses remains unsatisfactory. It is mainly because each process of AI causes a detrimental effect on semen quality. To sustain quality of semen properly, several factors including libido of stallions and sperm damage during sperm processing and preservation should be considered. Stallions with decent libido produce a high ratio of sperm to seminal plasma in their ejaculates, which is the ideal semen composition for maintaining sperm quality. Thus, to maximize the fertility rate upon AI, stallions should be appropriately managed to enhance their libido. Seminal plasma should have a positive effect on horse fertility in the case of natural breeding, whereas the effects of seminal plasma on both sperm viability and quality in the context of AI remain controversial. Centrifugation of semen is performed during semen processing to remove seminal plasma and to isolate fine quality sperm from semen. However, the centrifugation process can also result in sperm loss and damage. To solve this problem, several different centrifugation techniques such as Cushion Fluid along with dual and single Androcoll-E$^{TM}$ were developed to minimize loss of sperm and to damage at the bottom of the pellet. Most recently, a new technique without centrifugation was developed with the purpose of separating sperm from semen. AI techniques have been advanced to deliver sperm to optimal region of female reproductive tract at perfect timing. Recombinant equine luteinizing hormone (reLH) and low dose insemination techniques have been developed to maximize both fertility rate and the efficiency of AI. Horse breeders should consider that the entire AI procedure should be optimized for each stallion due to variation in individual horses for a uniformed AI protocol.

• 한국잠사곤충학회지
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• 제44권1호
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• pp.9-12
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• 2002

한반도에 자생하는 돌뽕나무(Morus tiliaefolia)의 임성과 재배학적 특성은 다음과 같다. 1. 종자형성률은 46∼80%이며 종자의 발아율은 19∼28%에 불과하다 2. 개화최성기(1994년)는 4월 28일∼5월 3일로서 산뽕나무보다는 늦고 개량뽕보다 빠르다 3. 춘기 동아의 탈포기는 4월 21일∼24일로서 산뽕나무와 개량뽕보다 늦다. 4. 잎은 대형으로 엽형지수 1.05의 폭광성을 나타내며 잎두께는 산뽕나무보다 두껍다. 5.성숙엽의 화학성분은 가용성 무질소물과 조회분이 많고 조단백질, 조지방, 조섬유가 적다. 6. 낮추베기때의 자세는 대부분 전개성이며 가지는 조장형이고 절간장이 길다 7. 추위견딜성과 뽕나무 동고병에 약하다.

• Asian-Australasian Journal of Animal Sciences
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• 제28권5호
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• pp.605-611
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• 2015

A synthetic strain of ducks (Anas platyrhynchos) was developed by introducing genes for long duration of fertility to be used as mother of mule ducklings and a seven-generation selection experiment was conducted to increase the number of fertile eggs after a single artificial insemination (AI) with pooled Muscovy semen. Reciprocal crossbreeding between Brown Tsaiya LRI-2 (with long duration of fertility) and Pekin L-201 (with white plumage mule ducklings) ducks produced the G0. Then G1 were intercrossed to produce G2 and so on for the following generations. Each female duck was inseminated 3 times, at 26, 29, and 32 weeks of age. The eggs were collected for 14 days from day 2 after AI. Individual data regarding the number of incubated eggs (Ie), the number of fertile eggs at candling at day 7 of incubation (F), the total number of dead embryos (M), the maximum duration of fertility (Dm) and the number of hatched mule ducklings (H) with plumage colour were recorded. The selection criterion was the breeding values of the best linear unbiased prediction animal model for F. The results show high percentage of exhibited heterosis in G2 for traits to improve (19.1% for F and 12.9% for H); F with a value of 5.92 (vs 3.74 in the Pekin L-201) was improved in the G2. Heritabilities were found to be low for Ie ($h^2=0.07{\pm}0.03$) and M ($h^2=0.07{\pm}0.01$), moderately low for Dm ($h^2=0.13{\pm}0.02$), of medium values for H ($h^2=0.20{\pm}0.03$) and F ($h^2=0.23{\pm}0.03$). High and favourable genetic correlations existed between F and Dm ($r_g=0.93$), between F and H ($r_g=0.97$) and between Dm and H ($r_g=0.90$). The selection experiment showed a positive trend for phenotypic values of F (6.38 fertile eggs in G10 of synthetic strain vs 5.59 eggs in G4, and 3.74 eggs in Pekin L-201), with correlated response for increasing H (5.73 ducklings in G10 vs 4.86 in G4, and 3.09 ducklings in Pekin L-201) and maximum duration of the fertile period without increasing the embryo mortality rate. The average predicted genetic response for F was 40% of genetic standard deviation per generation of selection. The mule ducklings' feather colour also was improved. It was concluded that this study provided results for a better understanding of the genetics of the duration of fertility traits in the common female duck bred for mule and that the selection of a synthetic strain was effective method of improvement.

• 한국지역사회생활과학회지
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• 제17권1호
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• pp.23-37
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• 2006

As the fertility rate of Korea has recently decreased to the lowest level in the world, the recognition of the needs for social support for the child-care has been increased. This resulted in the announcement of National Policy of Child-Rearing Support in 2004. This study attempted to propose the activation of the family child-care for the preparation of the introduction of the National Policy of Child-Rearing Support. Using literature review and interview, the following research questions were addressed. Firstly, the actual situation of the family child-care was compared with that of the other types of child-care. Secondly, the policies of child-rearing support and the family child-care systems in other countries such as United Kingdom, Sweden and Japan were introduced. Finally, activations of the family child-care were discussed in terms of the introduction of the National Policy of Child-Rearing Support. The results of this study implies that the family child-care in Korea is different from that of other countries as well as other types of child-care in Korea. Also, it suggests that key factors of the activation of the family child-care in Korea are to identify as the small, informal and family-like child-care, to differentiate as the infant-care and non-standard time child-care from other types of child-care, and to increase the level of professionalization. In conclusion, family child-care should become an alternative for the low fertility problem.

• 동남아시아연구
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• 제20권3호
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• pp.147-182
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• 2010

The purpose of this study is to examine the population changes in the nine Southeast Asian countries, including Cambodia, Lao People's Democratic Republic, Philippine, Indonesia, Malaysia, Myanmar, Singapore, Vietnam, and Thailand. According to the demographic transition theory which described the transition from high birth and death rates to low birth and death rates, the demographic changes in less developed countries, including the Southeast Asian countries, follow the general pattern of the population changes that the Western countries had experienced. However, this theory does not consider the fact that the demographic behaviors such as fertility and mortality tend to be ethnocentric (or particular). Therefore, I examine in this paper both the generality and particularity of the population changes in the Southeast Asia . The analytic results are consistent with my assumptions. Every country in the Southeast Asia will soon reach the third phrase of the demographic transition and meet population ageing process. However, the timings arriving at the third phrase can differ. Singapore which is the most developed country had firstly passed through the demographic transition and the highest level of population ageing. Cambodia and Lao People's Democratic Republic, the least developed countries, will lastly arrive at the third phrase and the ageing society. In addition, among the three countries which had experienced war or civil war, only Cambodia had experienced babyboom.

• Human Ecology Research
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• 제57권3호
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• pp.353-367
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• 2019

This study investigates the influence of family-friendly workplace policies and organizational culture on the willingness of married female managers to have a child. The analysis includes 353 married female managers from the $6^{th}$ survey of the 2016 Korean Women Manager Panel. Factors that are found to influence the respondents include age, education, number of children, job position, promotional goals, accessibility to family leave, accessibility to shorter work hours during the child-rearing period, and organizational culture. Female managers who can easily use family leave or who have shorter work hours during the child-rearing period show a higher willingness to have a child. By contrast, those whose work places employ a fair and horizontal organizational culture are less willing to have a child. The introduction of family-friendly policies are not found to be statistically significant determinants of female managers' willingness to have a child. We find that influencing family-friendly policies between the first and second childbirth differ. The accessibility of family-friendly policies that affect the willingness of female managers to have a child when they have no child include parental leave, employer-supported childcare, and childcare subsidies. For improving their willingness to have a second child, accessibility to both family leave and shorter work hours during the child-rearing period are effective. In conclusion, the government should strongly consider micro-personal factors, such as family-friendly workplace practices and organizational culture, when executing policies to reverse the current trend of low fertility.