• 제목/요약/키워드: the fusion of science

검색결과 2,336건 처리시간 0.031초

Abnormal Behavior in Color Tracking in the Fringe-Field Switching (FFS) Liquid Crystal Display

  • Jung, Jun-Ho;Ha, Kyung-Su;Chae, Mi-Na;Cho, In-Young;Kim, Woo-Il;Kim, Dae-Hyun;Kim, Sung-Min;Lee, Seung-Hee
    • 한국정보디스플레이학회:학술대회논문집
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    • 한국정보디스플레이학회 2009년도 9th International Meeting on Information Display
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    • pp.616-619
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    • 2009
  • Color tracking behavior of in the fringe-field switching (FFS) mode using a liquid crystal with positive dielectric anisotropy has been studied. In the in-plane switching and vertical alignment devices, color chromaticity at normal direction changes from bluish to yellowish white linearly with increasing grey levels from dark to white state. Interestingly, abnormal behavior in color tracking is observed in FFS devices using a liquid crystal with positive dielectric anisotropy, that is, it changes from bluish to yellowish up to a certain middle grey level but turns over to bluish white with further increasing from a grey level to a fully white state. In this paper, we analyze this abnormal effect from the calculated and experimental results.

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Novel function of stabilin-2 in myoblast fusion: the recognition of extracellular phosphatidylserine as a "fuse-me" signal

  • Kim, Go-Woon;Park, Seung-Yoon;Kim, In-San
    • BMB Reports
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    • 제49권6호
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    • pp.303-304
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    • 2016
  • Myoblast fusion is important for skeletal muscle formation. Even though the knowledge of myoblast fusion mechanism has accumulated over the years, the initial signal of fusion is yet to be elucidated. Our study reveals the novel function of a phosphatidylserine (PS) receptor, stabilin-2 (Stab2), in the modulation of myoblast fusion, through the recognition of PS exposed on myoblasts. During differentiation of myoblasts, Stab2 expression is higher than other PS receptors and is controlled by calcineurin/NFAT signaling on myoblasts. The forced expression of Stab2 results in an increase in myoblast fusion; genetic ablation of Stab2 in mice causes a reduction in muscle size, as a result of impaired myoblast fusion. After muscle injury, muscle regeneration is impaired in Stab2-deficient mice, resulting in small myofibers with fewer nuclei, which is due to reduction of fusion rather than defection of myoblast differentiation. The fusion-promoting role of Stab2 is dependent on its PS-binding motif, and the blocking of PS-Stab2 binding impairs cell-cell fusion on myoblasts. Given our previous finding that Stab2 recognizes PS exposed on apoptotic cells for sensing as an "eat-me" signal, we propose that PS-Stab2 binding is required for sensing of a "fuse-me" signal as the initial signal of myoblast fusion.

The Mechanism of Membrane Fusion During the Infection of HIV

  • Yu Yeon Gyu
    • 한국미생물학회:학술대회논문집
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    • 한국미생물학회 2001년도 추계학술대회
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    • pp.97-101
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    • 2001
  • The fusion between viral envelope and target cell membrane is a central step of viral infection, and the fusion proteins located at viral envelope mediate such process. Gp41 of HIV is one of the fusion proteins whose structure and mechanism of membrane fusion had been extensively studied. Functionally important motives of gp41 are the N-terminus fusion peptide, the coiled-coil and the membrane proximal C-peptide regions. The role of these regions during the fusion process had been thoroughly examined. Specially, insertion of the fusion peptide into membrane and conformational change of the coiled-coil and C-peptide regions are assumed to be critical for the fusion mechanism. In addition, the coiled-coil region has been shown to interact with membrane, and the C-peptide region regulates the interaction in a dose dependent manner. Furthermore, fusion defective mutations of the coiled-coil region dramatically changed its binding affinity to membrane. These results suggested that the membrane binding property of the coiled-coil region is important for the fusion activity of gp41, and such property could be modulated by the interaction with the C-peptide region.

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JDL 자료융합 모델의 분산 자료융합 능력 개선 (Improving the Distributed Data Fusion Ability of the JDL Data Fusion Model)

  • 박규동;변영태
    • 한국군사과학기술학회지
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    • 제15권2호
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    • pp.147-154
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    • 2012
  • In this paper, we revise the JDL data fusion model to have an ability of distributed data fusion(DDF). Data fusion is a function that produces valuable information using data from multiple sources. After the network centric warfare concept was introduced, the data fusion was required to be expanded to DDF. We identify the data transfer and control between nodes is the core function of DDF. The previous data fusion models can not be used for DDF because they don't include that function. Therefore, we revise the previous JDL data fusion model by adding the core function of DDF and propose this new model as a model for DDF. We show that our model is adequate and useful for DDF by using several examples.

A Novel Multifocus Image Fusion Algorithm Based on Nonsubsampled Contourlet Transform

  • Liu, Cuiyin;Cheng, Peng;Chen, Shu-Qing;Wang, Cuiwei;Xiang, Fenghong
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • 제7권3호
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    • pp.539-557
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    • 2013
  • A novel multifocus image fusion algorithm based on NSCT is proposed in this paper. In order to not only attain the image focusing properties and more visual information in the fused image, but also sensitive to the human visual perception, a local multidirection variance (LEOV) fusion rule is proposed for lowpass subband coefficient. In order to introduce more visual saliency, a modified local contrast is defined. In addition, according to the feature of distribution of highpass subband coefficients, a direction vector is proposed to constrain the modified local contrast and construct the new fusion rule for highpass subband coefficients selection The NSCT is a flexible multiscale, multidirection, and shift-invariant tool for image decomposition, which can be implemented via the atrous algorithm. The proposed fusion algorithm based on NSCT not only can prevent artifacts and erroneous from introducing into the fused image, but also can eliminate 'block effect' and 'frequency aliasing' phenomenon. Experimental results show that the proposed method achieved better fusion results than wavelet-based and CT-based fusion method in contrast and clarity.

KSTAR장치의 TF MPS 냉각수시스템 시운전 결과 (The Test Result of Cooling Water System for KSTAR TF MPS)

  • 김영진;김상태;임동석;정남용;김동진;최재훈;이동근;김양수;박주식;이용운
    • 대한설비공학회:학술대회논문집
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    • 대한설비공학회 2008년도 동계학술발표대회 논문집
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    • pp.413-418
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    • 2008
  • The toroidal field magnet power supply (TF MPS) for the KSTAR was constructed in August, 2007 and started the operation for the commissioning in March, 2008. The main role of the TF MPS is to supply the electric power to the TF magnet of the KSTAR. The water cooling components of the TF MPS are 16 stacks, busbar of 70 meters. For the cooling of the TF MPS, the D I water cooling system was designed and installed. The water cooling system consists of several pumps, heat exchangers, D I water polishing system and so on. The water cooling system for the TF MPS was tested under the 15 kA current charging condition. In this paper be discussed about the system performance and other parameters.

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Topomer-CoMFA Study of Tricyclic Azepine Derivatives-EGFR Inhibitors

  • Chung, Jae-Yoon;Pasha, F.A.;Chung, Hwan-Won;Yang, Beom-Seok;Lee, Cheol-Ju;Oh, Jung-Soo;Moon, Myoung-Woon;Cho, Seung-Joo;Cho, Art E.
    • Molecular & Cellular Toxicology
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    • 제4권1호
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    • pp.78-84
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    • 2008
  • EGFR has been intensively investigated as a target to block the signal transduction pathway which stimulates cancer growth and metastasis. Studies about structure-activity relationship for tricyclic azepine derivatives were performed with topomer-CoMFA. The derived topomer-CoMFA model with steric and electrostatic field parameters based on fragment units gave reasonable statistics ($q^2$=0.561, $r^2$=0.679). The model explains why a halogen atom at the meta position of aniline is important to increases inhibitory activity. This comes from an electrostatically negative groups are favored near this region. The model also shows that there are sterically favored regions around methoxy group extended from oxazepine derivatives. The findings about steric and electrostatic effects can be utilized for designing new inhibitors.