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Study of threshold and opacity in three-dimensional CT volume rendering of oral and maxillofacial area (구강악안면영역의 3차원 CT 영상 재형성시 역치 및 불투명도에 대한 연구)

  • Choi, Mun-Kyung;Lee, Sam-Sun;Huh, Kyung-Hoe;Yi, Won-Jin;Choi, Soon-Chul
    • Imaging Science in Dentistry
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    • v.39 no.1
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    • pp.13-18
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    • 2009
  • Purpose: This study was designed to determine a proper threshold value and opacity in three-dimensional CT volume rendering of oral and maxillofacial area. Materials and Methods: Three-dimensional CT data obtained from 50 persons who were done orthognatic surgery in department of oral and maxillofacial radiology of Seoul National University retrospectively. 12 volume rendering post-processing protocols of combination of threshold(100HU, 150HU, 221HU, 270HU) and opacity (58%, 80%, 90%) were applied. Five observers independently evaluated image quality using a five-point range scale. The results were analyzed by receiver operating characteristic curves, ANOVA and Kappa value. And three oromaxillofacial surgeons chose the all images that they thought proper clinically in the all of images. Results: Analysis using ROC curves revealed the area under each curve which indicated a diagnostic accuracy. The highest diagnostic accuracy appear with 100HU and 58% opacity. and the lowest diagnostic accuracy appear with 221HU and 58% opacity that are being used protocol in department of oral and maxillofacial radiology of Seoul National University. But, no statistically significant difference was noted between any of the protocols. And the number of proper images clinically that chosen by three oromaxillofacial surgeons is the largest in the cases of protocol 8 (221HU, opacity 80%) and protocol 11 (270HU, opacity 80%) in one after the other. Conclusion: Threshold and opacity in volume rendering can be controled easily and these can be causes of making an diagnostic accuracy. So we need to select proper values of these factors.

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Lytic Action of Egg White Lysozyme Isolated from Ogol Fowl on Staphylococcus aureus Phage Type 29 (Staphylococcus aureus Phage Type 29에 대한 오골계 난백 Lysozyme의 용균성)

  • Oh, Hong Rock;Lee, Jong Soo;Kim, Chan Jo
    • Korean Journal of Agricultural Science
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    • v.14 no.2
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    • pp.286-294
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    • 1987
  • This experiment was carried out to investigate the bacteriolytic action of the egg white lysozyme isolated from Korean native Ogol fowl and to obtain the data for utilization of the enzyme as a food preservative. Staphyococcus aureus phage type 29 and Bacillus subtilis ATCC 6633 among the microorganisms tested were lyzed by the treatment with 0.05% lysozyme, but Staphylococcus aureus phage type 57 in addition to E. coli etc. was found to be a lysozyme- insensitive species. The lysis of S. aureus phage type 29 was maximized when incubated in nutrient broth (pH 7.0) at $37^{\circ}C$ for 24 hours and suspended it to absorbance 0.6 at 540nm in 0.05M sodium acetate but fer (pH 4.5) and then treated it with the 0.05% lysozyme for 30 min. at $30^{\circ}C$. It was found that the effect of 0.05% lysozyme in combination with 1% glycine on the growth inhibition of S. aurecus phage type 29 increased more 50% than that in the absence of glycine, but not effect with other any additeves and metal ions tested.

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Treatment of Ischial Pressure Sores with Both Profunda Femoris Artery Perforator Flaps and Muscle Flaps

  • Kim, Chae Min;Yun, In Sik;Lee, Dong Won;Lew, Dae Hyun;Rah, Dong Kyun;Lee, Won Jai
    • Archives of Plastic Surgery
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    • v.41 no.4
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    • pp.387-393
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    • 2014
  • Background Reconstruction of ischial pressure sore defects is challenging due to extensive bursas and high recurrence rates. In this study, we simultaneously applied a muscle flap that covered the exposed ischium and large bursa with sufficient muscular volume and a profunda femoris artery perforator fasciocutaneous flap for the management of ischial pressure sores. Methods We retrospectively analyzed data from 14 patients (16 ischial sores) whose ischial defects had been reconstructed using both a profunda femoris artery perforator flap and a muscle flap between January 2006 and February 2014. We compared patient characteristics, operative procedure, and clinical course. Results All flaps survived the entire follow-up period. Seven patients (50%) had a history of surgery at the site of the ischial pressure sore. The mean age of the patients included was 52.8 years (range, 18-85 years). The mean follow-up period was 27.9 months (range, 3-57 months). In two patients, a biceps femoris muscle flap was used, while a gracilis muscle flap was used in the remaining patients. In four cases (25%), wound dehiscence occurred, but healed without further complication after resuturing. Additionally, congestion occurred in one case (6%), but resolved with conservative treatment. Among 16 cases, there was only one (6%) recurrence at 34 months. Conclusions The combination of a profunda femoris artery perforator fasciocutaneous flap and muscle flap for the treatment of ischial pressure sores provided pliability, adequate bulkiness and few long-term complications. Therefore, this may be used as an alternative treatment method for ischial pressure sores.

The Effects of Steel-Fiber Reinforcement on High Strength Concrete Replaced with Recycled Coarse Aggregates More Than 60% (순환굵은골재 60% 이상 사용한 고강도 콘크리트에 대한 강섬유 보강 효과)

  • Kim, Yoon-Il
    • Journal of the Korean Recycled Construction Resources Institute
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    • v.4 no.4
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    • pp.404-417
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    • 2016
  • The purpose of this study is to examine the extent to which the deterioration in strength of high strength concrete of 60MPa replaced by a large amount of recycled coarse aggregates (more than 60% to 100% of replacement ratio) could be recovered with steel fiber reinforcement through material compressive strength test and shear failure test on short and middle beams and then to offer useful data for aggregate supply system of a sustainable resource circulation type. This study first examined the results of previous related tests. The results of the material compressive strength tests confirmed that when using a combination of steel fiber reinforcements of volumn ratio 0.75% and high quality recycled coarse aggregates with an water absorption rate within 2.0%, the strength characteristics of high strength concrete of 60MPa level were not only restored to the strength level of concrete made with natural aggregates, but also showed superior ductility. And the shear failure tests on short and middle beams using recycled coarse aggregates more than 60% with shear span to depth ratio (a/d) of 2 and 4 controlled by shear forces mainly confirmed that effects of superior shear strength increase and ductile behavior characteristics were showed by steel fiber reinforcements.

Development of Neural Network Model for Estimation of Undrained Shear Strength of Korean Soft Soil Based on UU Triaxial Test and Piezocone Test Results (비압밀-비배수(UU) 삼축실험과 피에조콘 실험결과를 이용한 국내 연약지반의 비배수전단강도 추정 인공신경망 모델 개발)

  • Kim Young-Sang
    • Journal of the Korean Geotechnical Society
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    • v.21 no.8
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    • pp.73-84
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    • 2005
  • A three layered neural network model was developed using back propagation algorithm to estimate the UU undrained shear strength of Korean soft soil based on the database of actual undrained shear strengths and piezocone measurements compiled from 8 sites over the Korea. The developed model was validated by comparing model predictions with measured values about new piezocone data, which were not previously employed during development of model. Performance of the neural network model was also compared with conventional empirical methods. It was found that the number of neuron in hidden layer is different for the different combination of transfer functions of neural network models. However, all piezocone neural network models are successful in inferring a complex relationship between piezocone measurements and the undrained shear strength of Korean soft soils, which give relatively high coefficients of determination ranging from 0.69 to 0.72. Since neural network model has been generalized by self-learning from database of piezocone measurements and undrained shear strength over the various sites, the developed neural network models give more precise and generally reliable undrained shear strengths than empirical approaches which still need site specific calibration.

Evaluation of Therapeutic Differences of Angiotensin II Receptor Blockers and Calcium Channel Blockers Among Hypertensive Patients Classified by Oriental Traditional Way (한국적 의학 기준에 근거한 고혈압환자의 Angiotensin II Receptor Blockers와 Calcium Channel Blockers의 약물 평가)

  • Lee, Ok Sang;Cheon, Young Ju;Ye, Kyong Nam;Yoon, Hee Young;Kim, Jung Tae;Lee, Yun Jeong;Lim, Sung Cil
    • YAKHAK HOEJI
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    • v.58 no.2
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    • pp.141-149
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    • 2014
  • Background: Oriental lifestyle for treating diseases has been developed and well-accepted for a long time among Koreans. Sasang Constitution theory, originated from Korean traditional medicine, suggests that medication treatment should be differentiated by each patient's body classification (So-yang [SY], So-eum [SE], Tae-yang [TY], and Tae-eum [TE]), in contrary to western medicine's theory that medication should be applied equally by disease indication without such classification. However, the pharmacotherapeutic outcomes of these theories have not been compared to date. In this study, we aimed to compare the two theories by evaluating blood pressure (BP), which is lowered as a therapeutic outcome, among hypertensive patients taking angiotensin II receptor blockers (ARBs) or calcium channel blockers (CCBs), two most commonly used antihypertensive classes in Korea. Methods: From April 2006 to June 2012, we retrospectively collected data on hypertensive patients with Sasang Constitution classification at Kyunghee University Hospital at Gangdong, one of the East-West collaborative medical centers in Korea. We collected information on age, gender, underlying diseases, antihypertensive drugs (ARB, CCB, ARB+CCB), and BP by reviewing the electronic medical records. We excluded patients with missing blood pressure at baseline or follow-up, or those who had a change in their antihypertensive drug class during follow-up. Results: We selected a total of 573 patients (SY: 165, SE: 158, TY: 0, TE: 250). Baseline BPs were on average 139.0/82.0 mmHg for SY, 137.8/78.5 mmHg for SE, and 138.7/79.2 mmHg for TE. In all three groups, CCBs were the most prescribed, followed by combination therapy with ARB+CCB, then ARBs. BP reduction after 1 month of initial medication was significantly different among the drug classes, but not in Sasang constitutional classification (ARB [SY: -12.4/-4.7, SE: -12.3/-2.5, TE: -8.6/-1.8], CCB [SY: -12.3/-5.4, SE: -13.0/-2.3, TE: -10.8/-6.0], ARB+CCB [SY: -15.6/-6.7, SE: -18.4/-8.1, TE: -20.2/-6.7], drug [$P{\leq}0.05$/P>0.05], constitutional type [P>0.05/P>0.05]). Conclusion: We observed significant differences in reduction of blood pressure by classes of drugs (ARB+CCB>CCB>ARB) but not by Sasang constitutional classification. Therefore, current approach of antihypertensive pharmacotherapy assisted by Western medicine is appropriate for treatment of hypertension. However, further larger scale or prospective studies are required in order to confirm these results.

Flexural and Workable Properties of High Performance Hybrid Fiber Reinforced Concrete (고성능 하이브리드 섬유 보강 콘크리트의 휨 및 유동 특성)

  • Park Choon-Keun;Noh Myung-Hyun;Park Tae-Hyo
    • Journal of the Korea Concrete Institute
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    • v.17 no.4 s.88
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    • pp.543-550
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    • 2005
  • In the present work, modulus of rupture (MOR), flexural toughness properties $(I_{30}\;and\;W_{2.0})$ and workability (slump) of high performance hybrid fiber reinforced concrete (HPHFRC) mixed with micro-fiber (carbon fiber) and macro-fiber (steel fiber), and replaced with a fine mineral admixture such as silica fume (SF) are characterized through the analysis of variance (ANOVA). Data of MOR, $I_{30}(or W_{2.0})$ and slump are used as the characteristic values to estimate flexural performance and workable property of HPHFRC. Specially, an experimental design was Planned according to the fractional orthogoanl nay method to reduce experimental number of times. The experimental results show that steel fiber is a considerable significant factor in MOR and I30 $(W_{2.0})$. Based on the significance of experimental factors about each characteristic factors, the following evaluation can be used: Experiment factors which reduce slump most remarkably are carbon fiber, steel fiber, silica fume order.; Those that improve MOR most significantly are silica fume $({\fallingdotseq}\;carbon\;fiber)$, steel fiber order; Those that increase flexural toughness most distinctly are silica fume, carbon fiber, steel fiber order. It is obtained that the combination of steel fiber $1.0\%$, carbon fiber $0.25\%$ and silica fume $5.0\%$ is the experimental condition that improve MOR and flexural toughness excellently with workability ensured within the experiment.

Dependency-based Framework of Combining Multiple Experts for Recognizing Unconstrained Handwritten Numerals (무제약 필기 숫자를 인식하기 위한 다수 인식기를 결합하는 의존관계 기반의 프레임워크)

  • Kang, Hee-Joong;Lee, Seong-Whan
    • Journal of KIISE:Software and Applications
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    • v.27 no.8
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    • pp.855-863
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    • 2000
  • Although Behavior-Knowledge Space (BKS) method, one of well known decision combination methods, does not need any assumptions in combining the multiple experts, it should theoretically build exponential storage spaces for storing and managing jointly observed K decisions from K experts. That is, combining K experts needs a (K+1)st-order probability distribution. However, it is well known that the distribution becomes unmanageable in storing and estimating, even for a small K. In order to overcome such weakness, it has been studied to decompose a probability distribution into a number of component distributions and to approximate the distribution with a product of the component distributions. One of such previous works is to apply a conditional independence assumption to the distribution. Another work is to approximate the distribution with a product of only first-order tree dependencies or second-order distributions as shown in [1]. In this paper, higher order dependency than the first-order is considered in approximating the distribution and a dependency-based framework is proposed to optimally approximate the (K+1)st-order probability distribution with a product set of dth-order dependencies where ($1{\le}d{\le}K$), and to combine multiple experts based on the product set using the Bayesian formalism. This framework was experimented and evaluated with a standardized CENPARMI data base.

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Eastern and Western Combined Medical Treatments on 11 Patients with Dry Eye Syndrome (안구건조증환자 11례의 한·양방 병용치료에 대한 임상보고)

  • Lee, Dong-Jin;HwangBo, Min;Seo, Hyung-Sik;Kim, Soo-Jin;Lee, Jong-Soo
    • The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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    • v.25 no.2
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    • pp.61-67
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    • 2012
  • Objective : The endpoint of this trial is to verify therapeutical availability of conventional western eyedrops combined with acupuncture treatment by means of BUT(tear film break-up time), Schirmer's test, which have been considered to be typical methods for diagnosing dry eye syndrome. Methods : The subjects of this trial included the outpatients who had been diagnosed with dry eye syndrome in Pusan national university hospital and underwent acupuncture treatment from March 2011 to April 2011. They received acupuncture treatment once a week, three times while constantly using Restasis or artificial tears. We collated and analyzed the outcome data of Schirmer's test and BUT conducted at the beginning of this trial and three times more after each acupuncture treatments. Acupoints, such as, Chanjuk(BL2), Eoryo, Sajukgong(TE23), Taeyang, Sabaek(ST2), limited around both eyes were selected based on their clinical effects referring to medical books. Results : 1. From BUT test results, Restasis and acupuncture combined group showed statistically significant difference, however, artificial tears and acupuncture combined group showed difference only between before and after the treatment, which is not statistically significant. 2. From Schirmer's test results, Restasis and acupuncture combined group showed statistically significant difference, however, artificial tears and acupuncture combined group showed difference only between before and after the treatment, which is not statistically significant. 3. The average duration of treatment was statistically 16.3 days for Restasis and acupuncture combined group. Conclusions : Combination of acupuncture and Restasis for dry eye syndrome can shorten the duration of treatment. Therefore, clinical benefit is expected to be worth.

Development of Incident Detection Algorithm Using Naive Bayes Classification (나이브 베이즈 분류기를 이용한 돌발상황 검지 알고리즘 개발)

  • Kang, Sunggwan;Kwon, Bongkyung;Kwon, Cheolwoo;Park, Sangmin;Yun, Ilsoo
    • The Journal of The Korea Institute of Intelligent Transport Systems
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    • v.17 no.6
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    • pp.25-39
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    • 2018
  • The purpose of this study is to develop an efficient incident detection algorithm by applying machine learning, which is being widely used in the transport sector. As a first step, network of the target site was constructed with micro-simulation model. Secondly, data has been collected under various incident scenarios produced with combination of variables that are expected to affect the incident situation. And, detection results from both McMaster algorithm, a well known incident detection algorithm, and the Naive Bayes algorithm, developed in this study, were compared. As a result of comparison, Naive Bayes algorithm showed less negative effect and better detect rate (DR) than the McMaster algorithm. However, as DR increases, so did false alarm rate (FAR). Also, while McMaster algorithm detected in four cycles, Naive Bayes algorithm determine the situation with just one cycle, which increases DR but also seems to have increased FAR. Consequently it has been identified that the Naive Bayes algorithm has a great potential in traffic incident detection.