• Clinical and Experimental Pediatrics
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• 제53권2호
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• pp.190-194
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• 2010

목 적 : 애성 및 음성 변동은 심장병 환자에서 관찰될 수 있는데 이러한 음성 변동 정도를 음향학적 지표의 평가로 분석하여, 소아에서 선천성 심장병 종류에 따른 음성 변동을 음향학적 요소로 분석하고자 하였다. 방 법 : 수술 전 선천성 심장병 환아 94명을 연구 대상으로 하였고 심실 중격 결손, 동맥관 개존, 심방 중격 결손, 폐동맥 협착, 활로 사징이 포함되었으며, 음성 변동을 조사하기 위한 음향 지표 분석은 통증 자극을 통하여 얻어진 음성 자료를 multi-dimensional voice program system을 이용하여 평가하였다. 연구에 사용된 음향 지표로 average fundamental frequency, length of analyzed sample, jitter percent, shimmer, noise to harmonic ratio를 분석하였다. 결 과 : 음향 지표인 average fundamental frequency은 동맥관 개존, 심실 중격 결손, 활로 사징 경우에서 유의한 감소를 나타냈으며, length of analyzed sample은 연구 대상 선천성 심장병 환아에서 대조군에 비해 의미있는 차이를 나타내지 않았다. Jitter percent, shimmer, noise to harmonic ratio는 심실 중격 결손, 동맥관 개존, 심방 중격 결손에서 대조군에 비해 증가되었다. 이러한 음성 변동은 연구 대상 선천성 심장병 중 동맥관 개존에서 음도변이, 강도변이, 음성의 소음 정도가 가장 뚜렷하게 나타났으며, 동맥관 개존, 심실 중격 결손, 심방 중격 결손 순으로 그 음성 변동의 특징을 나타냈다. 결 론 : 수술 전 선천성 심장병 환아에서 음성을 음향학적 지표로 비교 분석한 결과 음향학적 지표들이 심장 질환의 유형별 차이를 보이는데 좌우 단락 심질환군에서 현저한 비정상적 음향학적 지표를 나타냈다.

• Journal of Chest Surgery
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• 제36권4호
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• pp.255-260
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• 2003

최근 활로 4징 교정술의 향상된 성적에도 불구하고, 수술 후 폐동맥 폐쇄부전과 우심실 유출로 확장으로 인한 좌폐동맥의 뒤틀림과 협착의 가능성이 보고되고 있다. 이에 좌폐동맥의 협착이 동반되었거나 협착이 없더라도 우심실 유출로 첩포 확장 시 좌폐동맥이 예각을 이루어 좌폐동맥 뒤틀림의 가능성이 있는 환자에서 첩포를 사용하지 않고 자가 주폐동맥 플랩만을 이용한 새로운 좌폐동맥 혈관성형술의 결과를 보고하고자 한다. 대상 및 방법： 1998년 10월부터 2001년 1월까지 24명의 활로4징 환자에서 완전교정술 시 좌폐동맥 입구를 자가 주폐동맥 플랩을 이용하여 선택적으로 혈관성형술을 시행하였다. 환자의 연령(중앙값)은 10개월(4∼145개월)이었다. 주폐동맥 플랩 좌폐동맥 성형술은 좌폐동맥 입구의 협착이 있었던 19예(79%)와 해부학적 협착은 없었으나 주폐동맥과 좌폐동맥이 예각을 이루어 좌폐동맥 뒤틀림의 위험이 예상되는 5예(21%)에서 시행되었다. 결과: 수술 사망예는 없었다. 24명 중 15명(62%)에서 경판막윤 우심실유출로 확장술을 시행하였으며, 나머지 9명에서 폐동맥 판막윤을 보존하면서 폐동맥 혹은 누두부 확장술을 시행하였다. 24명 중 5명(21%)에서는 어떤 첩포도 사용하지 않고 자가 주폐동맥 플랩만으로 좌폐동맥을 포함한 주폐동맥확장술을 시행하였다. 1 명을 제외한 23명의 추적관찰 기간(중앙값)은 20개월(6∼42개월)이었으며, 만기 사망 및 재수술의 예는 없었다. 2명에서 우폐동맥 근위부 협착으로, 1명에서 좌, 우폐동맥 입구의 협착으로 풍선 혈관성형술이 필요하였다. 결론: 주폐동맥 플랩을 이용한 좌폐동맥 성형술의 보다 장기적인 관찰이 필요하나, 첩포를 사용하지 않아 이와 관련된 문제점들을 피할 수 있고, 자가 주폐동맥플랩의 성장을 기대할 수 있을 것으로 생각된다. 또한 주폐동맥과 좌폐동맥 사이를 둔각으로 유지함으로써 향후 폐동맥 폐쇄부전과 관련된 우심실유출로 확장에 의한 좌폐동맥의 뒤틀림의 가능성을 줄일 수 있을 것으로 생각한다.

• Journal of Chest Surgery
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• 제16권1호
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• pp.18-29
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• 1983

Thirty-two patients with a cyanotic cardiac malformations having more complex intracardiac defects than ones in a tetralogy of Fallot underwent complete intracardiac repairs in a-full-year period from July 1981 to June 1982. Twenty-two patients [68.8%] died within 30 days after surgery: Transposition of the great arteries, seven of 10 patients; Double-outlet right ventricle, four of 6 patients; Tricuspid atresia, four of 6 patients; Single ventricle, all of 4 patients; Pulmonary atresia, two of 3 patients; Double-outlet left ventricle, none of 2 patients; and Truncus arteriosus, one of a single patient. All deaths occurred with a low cardiac output syndrome or a failed off-bypass, and they were almost always accompanied with other grave postoperative complications. The complex intracardiac anatomy itself was one of the risk factors by making a complete intracardiac repair of the defects difficult in a small heart. The reconstruction of the right ventricular outflow carried a difficulty in balancing an adequate relief of the obstruction with an avoidance of making too much pulmonary valvular insufficiency as well. On the other hand, the presence of an elevated pulmonary arterial pressure and a high pulmonary vascular resistance was also the factors affecting the postoperative surviv als. The importance of detailed knowledge of intracardiac anatomy and hemodynamics from the careful preoperative evaluation of the patient was discussed along with the necessity of technical refinement of the correction.

• Journal of Chest Surgery
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• 제28권8호
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• pp.747-753
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• 1995

Patients over 14 years of age who have undergone a surgical correction of a congenital cardiac malformations during period of August 1959 through December 1993 have been reviewed. During this period, there were 6894 cases of congenital cardiac lesions consisting of 4576 acyanotic and 2318 cyanotic cases. Among them, a total of 1389 adults [20.1%with various congenital cardiac malformations, 1126 acyanotic group and 263 cyanotic group were operated on. 677 patients were male and 712 patients were female. There were 444 patients under 20 years of age, 365 patients between 20-24 years, 220 patients between 25-29 years, 138 patients between 30-34 years and 222 patients over 34 years. The most common defects were atrial septal defect which accounted for 500 cases [36.0%and another common malformations were ventricular septal defect [276 cases, 19.9% , patent ductus arteriosus [207 cases, 14.9% , tetralogy of Fallot [185 cases, 13.3%and pulmonary stenosis [44 cases, 3.2%in order of incidence. Overall operative mortality for this series was 2.7% [1.5% of acyanotic group and 7.9% of cyanotic groupcompared with 4.6% of operative mortality of total cases of congenital cardiac malformations [2.9% of acyanotic group and 16.7% of cyanotic group . This reviewed series reveals the incidence of operable congenital heart defects appearing in any adult life and demonstrates that surgical repair can be accomplished with a satisfactory low mortality rate.

• Journal of Chest Surgery
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• 제16권4호
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• pp.431-443
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• 1983

A hundred and fifty-one patients with congenital heart disease less than 24 months old underwent intracardiac repairs from January 1982 to July 1983, which consists 24.2% of all the patients with congenital heart diseases operated during the same period. There were 98 patients[64.9%] with acyanotic congenital heart disease and 53 patients[35.1%] with cyanotic congenital heart disease, and 55 patients[36.4%] were less than 1 year of age. Twenty-two patients died within 30 days after surgery and 3 patients died after postoperative 30th day: Ventricular septal defect, four of 90 patients; Tetralogy of Fallot, five of 23 patients; Transposition of great arteries, nine of 17 patients; Tricuspid atresia, four of 5 patients; Pulmonary atresia, all of 2 patients; Single ventricle, one of single patients. Over all mortality was 16.6% and mortality of acyanotic congenital heart disease, cyanotic congenital heart disease and patients less then 1 year of age was 4.1%, 39.6% and 20.0% respectively. Still the mortality of cyanotic congenital heart disease is high. Careful preoperative evaluation of the detailed intracardiac anatomy and hemodynamics of the patients and proper selection of surgical treatment yield better clinical results.

• Journal of Chest Surgery
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• 제19권2호
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• pp.250-258
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• 1986

From Aug. 1984 to May 1986, 116 cases of cardiovascular surgery including 85 cases of open heart surgery were performed at Korea Veterans Hospital. There were 108 congenital anomalies and 8 acquired valvular heart diseases. Among 108 congenital malformations 92 operations were done for acyanotic group, and 16 operations for cyanotic group. Thirteen cases of open heart surgery for infants or small children under 10kg of body weight were performed, which occupied 15.3 percent of total open heart surgery done in the same period. Common congenital cardiovascular anomalies were ventricular septal defect [40.7%], patent ductus arteriosus [29.6%], tetralogy of Fallot [12.[%], atrial septal defect [11.1%], and pulmonary stenosis [1.9%] in order of frequency. Valve replacement using lonescu-Shiley or Carpentier-Edwards valve was performed for 8 cases of acquired mitral valve disease, and valve replacement using St. Jude valve was done for a case of patent ductus arteriosus with severe mitral insufficiency. There was no mortality in acyanotic congenital malformations and acquired valve lesions, and 5 cases of mortality in cyanotic congenital malformations. Overall mortality was 4.3 percent for total cases and 5.9 percent for 85 cases of open heart surgery.

• Journal of Chest Surgery
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• 제32권11호
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• pp.1042-1045
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• 1999

Background: Recently, open heart surgerys using homograft are progressively increasing in complex cardiac anomalies, and even though the use of homograft tissues harvested from hearts of transplant recipients and brain-death patients are allowed and their use is increasing, the supply of homograft tissue is very limited. Material and Method: The large diameter homografts are difficult to apply directly for RVOT reconstruction of small neonatal and infant hearts due to the size mismatching. Therefore, were surgically down-sized the large diameter tricuspid homograft into bicuspid conduits by means of a longitudinal incision of the oversized homograft, excision of one cusp, and oversewing of the“Bicuspid homograft”wrapped around a Hega dilator of the appropriate size. Result: 3 patients(Male 1, Female 2: tetralogy of Fallot with pulmonary atresia), ranging in age from 5 months to 4 years and ranging in weight from 5.5Kg to 12.95Kg underwent reconstruction of the RVOT with bicuspid conduits obtained by appropriate tailoring from large-diameter homografts. The mean follow-up period was 4.3 months(range, 2 to 6 months). There were no complications related to the homograft tissues. Conclusion: In the short term follow-up, the bicuspid homografts provided good competence and excellent hemodynamics although a long term follow-up is needed to assess the functions of the bicuspid homografts in RVOT. We believe this technique may be a more effective alternative than the use of synthetic conduits when the use of an appropriate-sized homograft is not possible.

• Journal of Chest Surgery
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• 제11권2호
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• pp.213-226
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• 1978

One hundred cases of open heart surgery were done at this Department in 1977. There were 65 congenital anomaly and 35 acquired diseases. Out of 65 cases of congenital malformation 35 acyanotic and 30 cyanotic cases were found. Fifteen cases of ventricular septal defect and 29 tetralogy of Fallot were noted eight patients expired out of 65 congenital anomaly [12.3%] , 4 out of 35 acyanotic [11. 4%] and 4 among 30 cyanotic anomaly[13.3%]. Among 35 cases of acquired heart disease 3 atrial myxoma [2 left and one right] and 32 valvular lesions were noted. In two cases open mitral commissurotomy, and in 30 valve replacement were done. Twenty-two single valve and 8 double valve replacement were done. Seven patients expired out of 30 patients [23.3%]. Among 22 single valve replacement cases 2 and among 8 double valve 5 died. ~ In eighteen mitral valve replacement cases 2 deaths occurred. One mitral insufficiency patient who expired suffered from severe pulmonary` hypertension [PA=120/67mmHg], tricuspid insufficiency and a large ventricular septal defect. The patient underwent mitral valve replacement, tricuspid annuloplasty and patch closure of ventricular septal defect. Over all mortality rate for 100 open heart surgery cases was 15%. Since 1977 open heart surgery cases were done routinely in this institution and cases are increasing rapidly. With present rapid improvement of economical status and introduction of medical insurance system, open heart surgery will be firmly established in Korea in the very near future.

• Clinical and Experimental Pediatrics
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• 제56권3호
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• pp.101-106
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• 2013

Despite developments in surgical techniques and other interventions, right ventricular (RV) failure remains an important clinical problem in several congenital heart diseases (CHD). RV function is one of the most important predictors of mortality and morbidity in patients with CHD. RV failure is a progressive disorder that begins with myocardial injury or stress, neurohormonal activation, cytokine activation, altered gene expression, and ventricular remodeling. Pressure-overload RV failure caused by RV outflow tract obstruction after total correction of tetralogy of Fallot, pulmonary stenosis, atrial switch operation for transposition of the great arteries, congenitally corrected transposition of the great arteries, and systemic RV failure after the Fontan operation. Volume-overload RV failure may be caused by atrial septal defect, pulmonary regurgitation, or tricuspid regurgitation. Although the measurement of RV function is difficult because of many reasons, the right ventricle can be evaluated using both imaging and functional modalities. In clinical practice, echocardiography is the primary mode for the evaluation of RV structure and function. Cardiac magnetic resonance imaging is increasingly used for evaluating RV structure and function. A comprehensive evaluation of RV function may lead to early and optimal management of RV failure in patients with CHD.

• Journal of Chest Surgery
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• 제21권4호
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• pp.641-648
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• 1988

Between April 9, 1986 and September 2, 1987, 134 patients underwent open heart surgery with hypothermic cardiopulmonary bypass and cold blood cardioplegia. There were 65 patients[48.5%] of acyanotic congenital cardiac anomalies, 19 patients[14.2%] of cyanotic congenital cardiac anomalies, and 50 patients[37.3%] of acquired heart diseases, which included 49 valvular diseases and 1 myxoma. In 84 congenital cardiac anomalies, 44 patients were male and 40 patients were female ranged in age from 2 years to 57 years. In 50 acquired heart diseases, 18 patients were male and 32 patients were female ranged in age from 10 years to 65 years. The common congenital defects operated were VSD in acyanotic cardiac patients, and Tetralogy of Fallot in cyanotic cardiac patients. Among 50 acquired heart diseases, 49 patient underwent operation for cardiac valvular lesions. 33 patients had mitral valve replacement and 7 patients had aortic valve replacement. 1 patient underwent aortic valvuloplasty and 8 patients had double valve replacement. The operative mortality rate was 3.1%[2 out of 65 patients] in acyanotic cardiac patients, 5.3%[1 out of 17 patients] in cyanotic cardiac patients, and 12.0%[6 out of 50 patients] in acquired cardiac patients, with overall mortality rate of 6.7%[9 out of 134 patients].