• Applied Biological Chemistry
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• 제16권3호
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• pp.112-117
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• 1973

The very low density apolipoproteins were separated by a newly developed method of isoelectric focusing in a narrow pH gradient. Four polypeptides were isolated that differed from the major proteins of the high density or low density lipoproteins. Three of these proteins had indistinguishable amino acid compositions, but different isoelectric points, COOH-terminal alanine, no isoleucine, cysteine or cystine. Two of these polypeptides had $NH_2-terminal$ serine. The polymorphism of apolipoprotein-Ala, so designated from the COOH-terminal residue, was related to sialic acid content; one form contained 2 moles of sialic acid per mole of protein, the second, 1 mole of protein, and the third, no sialic acid. The fourth polypeptide had an amino acid composition different from the first three polypeptides and from other polypetides obtained from very low density lipoprotein. This polypeptide had $NH_2-terminal$ threonine, COOH-terminal resistant to carboxypeptidase A, no histidine, cysteine, cystine or sialic acid. These four polypeptides constituted approx. 40% of the total protein in very low density lipoprotein.

• Geomechanics and Engineering
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• 제23권5호
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• pp.493-502
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• 2020

The prediction of soil response under repetitive mechanical loadings remains challenging in geotechnical engineering applications. Modeling the cyclic soil response requires a robust model validation with an experimental dataset. This study proposes a unique method adopting linearity of model constant with the number of cycles. The model allows the prediction of the terminal density of sediments when subjected to repetitive changes in pore-fluid pressure based on the two-surface plasticity. Model simulations are analyzed in combination with an experimental dataset of sandy sediments when subjected to repetitive changes in pore fluid pressure under constant deviatoric stress conditions. The results show that the modified plastic moduli in the two-surface plasticity model appear to be critical for determining the terminal density. The methodology introduced in this study is expected to contribute to the prediction of the terminal density and the evolution of shear strain at given repetitive loading conditions.

• Journal of Biosystems Engineering
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• 제23권6호
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• pp.583-590
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• 1998

This study was performed to determine the kinetic friction coefficient bulk density, dynamic and static angle of repose, and terminal velocity of the chopped rice straw in the moisture range of 8~23%, which could be used for better design and operation of the processing machinery and handling facilities. Friction coefficient was determined from the horizontal traction force measured by pulling the container holding the mass of rice straw on the various plate materials. Bulk density was measured with an apparatus consisting of a filling funnel and a receiving vessel. Dynamic angle of repose was calculated from the photos of bulk samples piled by gravity flow on a circular platform. Static angle of repose was determined by measuring the side angle of the bulk material which was left in the cylindrical container after natural discharge of the bulk sample through a circular hole in the bottom plate. Kinetic friction coefficients of rice straw on the PVC, mild steel, stainless steel, and galvanized steel were in the range of 0.303~0.434, 0.222~0.439, 0.204~0.448, and 0.206~0.407, respectively. and indicated linear increase with moisture content. The effects of moisture change on the friction coefficients were in the order of PVC, mild steel, galvanized steel, and stainless steel. Bulk density, dynamic and static angle of repose, and terminal velocity were in the range of 56.8~60.3 kg/m$^3$, 41.4~45.9$^{\circ}$, 94.4~100.8$^{\circ}$, and 1.07~4.48 m/s, respectively, and were increased linearly with the moisture content.

• 대한인간공학회:학술대회논문집
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• 대한인간공학회 1995년도 추계학술대회논문집
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• pp.62-74
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• 1995

This study surveys four characteristics (overall density, local density, grouping, complexity) to effect user's performance on the on-line terminal displays of commercial banks, and makes the new screen by the screen design procedure. The new screen includes to increase the number of groups and to arrange the items on the screen. And then, this study carrys out experiments to compare performance(operating time and error number ) by each screen. The result is described that the operating time decreases about 20% at the new OUT-screen than the existing OUT-screens; about 25% at the new IN-screen.

• Journal of Biosystems Engineering
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• 제30권4호
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• pp.229-234
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• 2005

Kinetic friction coefficient, bulk density, dynamic and static angle of repose, and terminal velocity of rice husk at the moisture range 7 to $23\%$ w.b. were determined. It could lead to better design and operation of the processing machinery and handling facilities. Friction coefficient was determined from the horizontal traction force measured by pulling the container holding a mass of rice husk on various plate materials. Dynamic angle of repose was calculated from the photos of bulk samples piled by gravity flow on a circular platform. Static angle of repose was determined by measuring the side angle of the bulk material which was left in a cylindrical container after natural discharge of the bulk sample through a circular hole in the bottom plate. Kinetic friction coefficients of rice husk were in the range of $0.254\~0.410,\;0.205\~0.520,\;0.229\~0.400,\;and 0.133\~0.420$ on PVC, mild steel, galvanized steel, and stainless steel, respectively. Bulk density, dynamic and static angle of repose, and terminal velocity were in the range of $91.7\~98.3$ $kg/m^3$, $40.2\~47.6^{\circ},\;52.8\~83.7^{\circ},$ and $1.36\~1.73$ m/s, respectively. These physical properties of rice husk increased linearly as the moisture content increased.

• 한국정보디스플레이학회:학술대회논문집
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• 한국정보디스플레이학회 2005년도 International Meeting on Information Displayvol.I
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• pp.464-467
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• 2005

In this paper, we present techniques to manufacture color electronic ink for multi-color electrophoretic display implementation. The charged color pigments have been prepared to have superior affinity for dielectric fluid. White $TiO_2$ nanoparticles were modified with poly(methyl methacrylate) copolymer for a microencapsulated electrophoretic display system, in order to reduce the density mismatch between nanoparticles and dielectric medium. These color balls and white pigment particle suspensions were microencapsulated through the typical microencapsulation technique. We fabricate the microcapsules to the single layer on flexible ITO substrate to test the multi-color electrophoretic display application.

• 대한전자공학회논문지
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• 제25권5호
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• pp.572-579
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• 1988

In this paper, a system of automatic placement and routing for gate array layout design is proposed. In the placement stage, the circuit is partitioned and using the concept of min-cut slicing, and each partitioned module is placed, so that the routing density over the entire chip be uniformized and the total wiring length be minimized. In the global routing stage, the concept of the probabilistic routing density is introduced to unify the wiring congestions in each channel. In the detailed routing stage, the multi-terminal nets are partitioned into the two-terminal nets. The ordered channel graph is proposed which implies the vertical and the horizontal constranint graphs simultaneously. And using the ordered channel graph, the proposed routing algorithm assigns the signal nets to the tracks. Also the proposed placement and routing algorithms are implimented on IBM/PC-AT to construct PC-level gate array layout system.

• Biomolecules & Therapeutics
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• 제29권5호
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• pp.527-535
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• 2021

Sclerostin (SOST), a regulator of bone formation in osteocytes, inhibits the canonical Wnt signaling by interacting with low-density lipoprotein receptor-related protein 5/6 (LRP5/6) to prevent Wnt binding. Loss-of-function mutations of the SOST gene caused massive bone outgrowth and SOST-null mouse exhibited a high bone density phenotype. Therefore, SOST has been suggested as a promising therapeutic target for osteoporosis. A few previous studies with X-ray crystallography identified the binding interfaces between LRP6 and SOST, but there are limitations in these studies as they used truncated SOST protein or SOST peptide. Here, we analyzed the conformational dynamics of SOST-LRP6 E1E2 complex using hydrogen/deuterium exchange mass spectrometry (HDX-MS). We examined the effect of the C-terminal tail of SOST on LRP6 conformation upon complex formation. HDX-MS analysis suggested a new potential binding interface for the C-terminal region of SOST that was missing from the previous crystal structure of the SOST-LRP6 E1E2 complex.

• 방사성폐기물학회지
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• 제3권2호
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• pp.77-84
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• 2005

실증용 UO$_{2}$ pellet 산화로의 실증을 위한 제한된 핫셀 공간 안에서 사용후 핵 연료를 취급하는 산화로는 소형화 하여야 하고, 사용후 핵 연료 분말은 UO$_{2}$ pellet 산화로 장치로부터 비산되지 않아야 한다. 본 연구에서는 분말의 최종속도를 구하기 위하여 Stokes식과 밀도비식을 제안하였다. U$_{3}$O$_{8}$ 의 최종속도 SiO$_{2}$ 의 최종속도를 사용하여 예측하였고, 비산방지를 할 수 있는 최적유량을 결정하였다. SiO$_{2}$ 의 이론 최종속도 식을 검증하고, U$_{3}$O$_{8}$ 과 관계식을 예측하기 위하여 아크릴 장치를 만들었다. 목업시설 에 설치 된 산화로에서 제안된 이론최종속도식 인 Stokes식 의 20 L/min과 밀도비식의 14.5 L/min을 적용하여 U$_{3}$O$_{8}$ 분말의 필터감지에 의해 검증하였다. 그 결과 밀도비식에 의한 14.5 L/min은 U$_{3}$O$_{8}$ 이전혀 검출되지 않았고, Stokes식의 20 L/min에서는 평균 7$\mu$m 의 입도분말이 검출되었다. 따라서 UO$_{2}$ pellet 산화로에서 U$_{3}$O$_{8}$이 비산되지 않는 최적유량은 14.5L/min임을 알 수 있었고, 제안된 밀도비식이 바람직함을 알 수 있었다.

• 한국항해항만학회:학술대회논문집
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• 한국항해항만학회 2023년도 춘계학술대회
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• pp.252-253
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• 2023

Container terminal automation might offer many potential benefits, such as increased productivity, reduced cost, and improved safety. Autonomous trucks can lead to more efficient container transport. A robust lane detection method is proposed using score-based generative modeling through stochastic differential equations for image-to-image translation. Image processing techniques are combined with Density-Based Spatial Clustering of Applications with Noise (DBSCAN) and Genetic Algorithm (GA) to ensure lane positioning robustness. The proposed method is validated by a dataset collected from the port terminals under different environmental conditions and tested the robustness of the lane detection method with stochastic noise.