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A study on the development of hydrocortisone certified reference material in cosmetic cream using isotope dilution-mass spectrometry (동위원소희석-질량분석법을 이용한 화장품 크림 중 히드로코르티손 인증표준물질 개발 연구)

  • Chae-Hong Lee;Ji-Sun Huh;Eun-Ji Jeong;Hyun-Ah Kim;Min-Young Eom
    • Analytical Science and Technology
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    • v.37 no.3
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    • pp.166-173
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    • 2024
  • Steroids have a temporary skin improvement and whitening effect by controlling vasodilation, but they also cause side effects when used for a long time. Therefore, steroids were designated and managed as raw materials that cannot be used in cosmetics in Korea. However, steroids are continuously being detected in cosmetics, causing social issues. In this study, we developed a certified reference material (CRM) for the determination of steroids such as hydrocortisone in cosmetics. A cream-type cosmetic CRM was manufactured and subsequently certified following the guidelines outlined in ISO Guide 35. Homogeneity, short-term stability, and long-term stability were evaluated using isotope dilution mass spectrometry (ID-MS). The certified values were determined by using NIST's primary reference material to ensure traceability. From now on, we intend to supply the certified reference material as a cosmetic CRM to national and international companies, as well as research institutes after certification as certified reference material from KOLAS and registering on COMAR.

Routing in Vehicular Ad Hoc Networks: Issues and Protocols

  • Shrestha, Raj K.;Moh, Sang-Man;Chung, Il-Yong
    • Korea Multimedia Society
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    • v.12 no.4
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    • pp.28-40
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    • 2008
  • Vehicular ad hoc networks (VANETs) are a practical application class of wireless ad hoc networks, which consist of moving vehicles equipped with radio communication capabilities that collaborate to form a temporary network. This paper addresses issues and protocols of multihop routing in such emerging networks in the context of safety and infotainment applications. Due to the highly dynamic mobility of vehicles, frequent link breakage and short connection time are inevitable and, thus, the routing is a challenging task and interest for many researchers and industrial community. The frequent and dynamic change of topology makes the topology-based routing unreliable but the position-based routing more effective. The position-based routing consists of the location service which maps a node id to a geo-graphical position and the forwarding scheme which selects the next hop based on geo-graphical information of the node, its neighbors and the destination. The routing techniques are further categorized into geographical forwarding, trajectory forwarding and opportunistic forwarding based on the forwarding scheme. In this paper, we first present the distinguished properties of VANETs and the challenges and intractable issues posed in designing the routing protocols, followed by the comprehensive survey of existing routing protocols. Then, the different routing protocols designed for VANETs are compared in terms of characteristics, performance and application domains.

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Secure GSM User Authentication Protocol For User Privacy (사용자 프라이버시를 위한 안전한 GSM 사용자인증 프로토콜)

  • Park, Mi-Og;Kim, Chang-Min
    • Journal of the Korea Institute of Information Security & Cryptology
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    • v.16 no.6
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    • pp.157-161
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    • 2006
  • GSM(Global System for Mobile communications) that is the most popular standard for mobile phones, has more than 70% users in the world and the number of users increase continuously. However GSM system has the problem that cannot normally authenticate a user by the exposure of IMSI that is able to uniquely authenticate MS? during the user authentication procedure. In this paper? we provide security enhancement and user privacy by adopting a temporary id and an encryption scheme. Moreover we provide fast user authentication via architecture modification of the conventional GSM user authentication protocol.

Modification of User Authentication Protocol for Partial Anonymity in the GSM System (GSM 시스템에서 부분적 익명성을 위한 사용자인증 프로토콜의 변형)

  • Park Mi-Og;Kim Sang-Geun
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.31 no.6C
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    • pp.645-650
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    • 2006
  • GSM(Global System for Mobile communications) provides mobile users with portability and convenience as the most popular standard for mobile phones in the world. However, GSM system has the problem that can't normally authenticate a user by the exposure of IMSI(International Mobile Subscriber Identity) of Ms(Mobile station) during the user authentication procedure. In this paper, we propose secure user authentication by preventing the exposure if IMSI via transfer the encrypted IMSI from the HLR(Home Location Register) and making the only network entities verified from the HLR use the IMSI value, as the modified mechanism based on the original user authentication protocol to solve this authentication problem. Also the proposed mechanism provides fast user authentication without changing the architecture between new VLR and old VLR in the original GSM user authentication protocol as well as user's anonymity by using a temporary ID.

The Characteristics of Population Flows in kwangju Metropolitan Area (光州 中心의 人口移動 特性에 관한 硏究)

  • Chouh, Hae-Chong
    • Journal of the Korean Geographical Society
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    • v.28 no.1
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    • pp.40-57
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    • 1993
  • This paper aims to show the various aspects of migration in Kwangju merropolitan area, southwestern Korea, for a period of years 1980-1985. Migratory patterns are spatially extensive in countryside around Kwanfju, and due to high accessibility to the metropolitan area urban implosion emerges in the city. In Chonnam province where Kwangju is loca-ted, all cities and counties except for such in-dustrial areas as Yochon, and Kwangyang are experiencing population losses in terms of net migration by survival rate methods. Kwangju is the exceptionally one of in-migration areas in Chonnam, though its central part(Dong-Gu) is also an out-migrated area. Predominantly in-migration urban areas have high proportions of a student age group between 15-19 years, and that reflects the importance of the educational factor in migration analysis. The municipal authorities of Kwangju are planning to block the way of the middle sxhool students who live in the outskirts of Kwangju to entrance to high school in the city. Thant may stir up migrations into Kwangju for the elementary and middle school students, because the city id expected to provide educational opportunities higher and better than remaining Chonnam areas. Population of Kwangju would, therefore, grow as the students migrate into the city. The findings on the residential intra-city movement in selected 5 Dongs indicate that implications of a short-distance movement re noteworthy; neighbour to neighbour, and the nearest stop in the way from the outer Kwangju as well. Trends in a short-distance movement are in accord with Ravensteins's "law of migra-tion". But in casw of the inter-provincial migra-tion to Kwangju, the number of in-migrants from remoter Seoul is more than that from nearer Chonbuk province. Therefore it supports the fact that the movement between capital region and far off local cities overcomes a distance barrier. The temporary mobility for a day has been increased as the standard of living has improved and it reaches a peak on weekend or on con-secutive holidays. The number of temporal movers to Kwangju from capital region and Yongnam area, southeastern Korea has a greatincrease in terms of the frequency of the passengers' mobility, in particular on Myongjol(the ethnic and traditional festival day) in com-parison with on weekdays. By comparison with two largest Myongjols, the number of movers is more on Chusok(The Full Moon festival on lunar August) than on Sol (lunar new year's day). Annual peak point of weekday movers appears in August because of summer vacation. But the lowest one appears in June, which is related to the busy farming season. A patients' move for medical services in on the increase with a change of living conditions. It is especially true in the industrial counties such as Kwangyang and Yochon. By way of conclusion, it should be pointed out that one of the problems we face in survey of migration volume by the survival rate method is that the survival rate somtimes exceeds the value 1.0, in normal states of which should be under 1.0. it may be due to the shortcoming from the census statistics. We should not give therefore too much stress on the importance of migrations or moves as an element of changes in spatial pattern. In cinclusion, the results of the study show some geographic facts as the followings: 1. One of the outstanding phenomena in all types of movement is the seletivity of ages. The most important factors are related to education and employment. 2. Short-distance movement is carried out in accordance with Ravenstein's law, but in case long-distance movement, in-migration from capital region is prominent in spite of remoten-ces. The gravity between large cities such as Kwangju and Seoul, which has a frequent human movenent, causes urban implosion of small cities between those cities. 3. The temporary mobility for a day, in con-trast to that of permanent movement, is more related to transportation, and its volumes and annual variations are a large-scale. 4. Passengers' mobility is high in industrial cities. And the scope of patients' mobility is narrower than passengers'.

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