• Clinical and Experimental Otorhinolaryngology
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• 제11권4호
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• pp.259-266
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• 2018

Objectives. Carcinomas of the external auditory canal (EAC) are rare, and management remains challenging. Previous studies seeking prognostic factors for EAC cancers included cancers other than carcinomas. In this study, we analyzed the treatment outcomes of, prognostic factors for, and survival rates associated with specifically squamous cell carcinoma (SCC) of the EAC. Methods. A retrospective review of 26 consecutive patients diagnosed with SCCs of the EAC in a 10-year period was performed in terms of clinical presentation, stage, choice of surgical procedure, and adjunct therapy. Overall survival (OS) and recurrence-free survival (RFS) were calculated and univariate analysis of prognostic factors was performed. Results. The median age of the 26 patients with SCCs of the EAC was 63 years (range, 40 to 72 years), and 16 males and 10 females were included. According to the modified University of Pittsburgh staging system, the T stages were T1 in 11, T2 in six, T3 in four, and T4 in five cases. The surgical procedures employed were wide excision in three cases, lateral temporal bone resection (LTBR) in 17, and extended LTBR in four, and subtotal temporal bone resection in two. Two patients underwent neoadjuvant chemotherapy, and two underwent adjuvant chemotherapy. One patient received preoperative radiation therapy, and eleven received postoperative radiation therapy. Of the possibly prognostic factors examined, advanced preoperative T stage and advanced overall stage were significant predictors of RFS, but not of OS. Conclusion. The advanced T stage and overall stage were associated with decreased survival after surgical treatment in patients with SCC of the EAC, highlighting the importance of clinical vigilance and early detection.

• 대한지리학회지
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• 제47권5호
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• pp.641-653
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• 2012

강원 영동지역의 천진호와 쌍호에서 확보한 석호 퇴적물을 분석한 결과, 천진호는 AD 780에, 쌍호는 100 BC에 벼농경이 개시된 것으로 추정된다. 두 지점이 멀지 않은 거리 내에 있고 해안으로 연결되어 있음에도 불구하고 벼농경 시작 시점에 큰 차이가 나타나고 있다. 이는 화분자료를 활용하여 특정지역 벼농경문화의 정확한 전파 시점을 파악하는 것이 쉽지 않음을 시사한다. 강원 영동 지역의 경우, 낮은 농경 생산성으로 말미암아 벼농경 문화가 최초로 전파된 시점과 벼농경이 본격적으로 시작된 시점 간에 시간적인 차이가 있었던 것으로 사료된다. 천진호 및 쌍호 분석 자료 모두에서 벼농경이 본격적으로 시작된 지 약 250년 후부터 농경지시화분들의 중요도가 더욱 커지고 산지의 침식이 빠르게 증가하는 모습이 나타난다. 이는 벼농경의 활성화로 인구가 증가함에 따라 저지대에서 산지로 거주지역의 확대가 나타났고 이로 인해 산림이 영향을 받았음을 시사한다.