• Title/Summary/Keyword: technical risk

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SARS-CoV-2 Antibodies in Children with Chronic Disease from a Pediatric Gastroenterology Outpatient Clinic

  • Kaya, Gulay;Issi, Fatma;Guven, Burcu;Ozkaya, Esra;Buruk, Celal Kurtulus;Cakir, Murat
    • Pediatric Gastroenterology, Hepatology & Nutrition
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    • v.25 no.5
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    • pp.422-431
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    • 2022
  • Purpose: At the beginning of the Coronavirus disease (COVID-19) epidemic, physicians paid close attention to children with chronic diseases to prevent transmission or a severe course of infection. We aimed to measure the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibody levels in children with chronic gastrointestinal and liver diseases to analyze the risk factors for infection and its interaction with their primary disease. Methods: This cross-sectional study analyzed SARS-CoV-2 antibody levels in patients with gastrointestinal and liver diseases (n=141) and in healthy children (n=48) between January and February 2021. Results: During the pandemic, 10 patients (7%) and 1 child (2%) had confirmed COVID-19 infection (p=0.2). The SARS-CoV-2 antibody test was positive in 36 patients (25.5%) and 11 children (22.9%) (p=0.7). SARS-CoV-2 antibody positivity was found in 20.4%, 26.6%, 33.3%, and 33.3% of patients with chronic liver diseases, chronic gastrointestinal tract diseases, cystic fibrosis, and liver transplantation recipients, respectively (p>0.05, patients vs. healthy children). Risk factors for SARS-CoV-2 antibody positivity were COVID-19-related symptoms (47.2% vs. 14.2%, p=0.00004) and close contact with SARS-CoV-2 polymerase chain reaction-positive patients (69.4% vs. 9%, p<0.00001). The use, number, and type of immunosuppressants and primary diagnosis were not associated with SARS-CoV-2 antibody positivity. The frequency of disease activation/flare was not significant in patients with (8.3%) or without (14.2%) antibody positivity (p=0.35). Conclusion: SARS-CoV-2 antibodies in children with chronic gastrointestinal and liver diseases are similar to that in healthy children. Close follow-up is important to understand the long-term effects of past COVID-19 infection in these children.

A Process of the Technical Performance Management for A Space Launch Vehicle R&D Project (우주발사체 개발사업을 위한 기술성능관리 프로세스)

  • Yoo, Il Sang;Cho, Dong Hyun;Kim, Keun Taek
    • Journal of the Korean Society of Systems Engineering
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    • v.10 no.2
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    • pp.71-79
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    • 2014
  • To enhance success probability of a system development project, its overall risk level should be minimized through systematically managing schedules, costs, and technical performances. However, Attempts to manage technical performance compared to numerous efforts to control costs and schedules in such projects are deficient. Particularly, a space launch vehicle, a large complex system, development project is much less likely to meet its technical performance objectives due to its technological difficulty, along with schedule delay and cost overrun. The technical performance management (TPM) is a method for tracking and managing technical progress in order to achieve technical performance targets within schedule and budget. In this paper, we investigate applications of the TPM in several space launch vehicle development projects. Then we propose and validate the TPM process to achieve a successful mission in such projects.

Establishing Risk Management Process for Improved Business Value of a Multi-Purpose Building Project (복합 시설 프로젝트의 사업 가치 향상을 위한 리스크 관리 프로세스 구축 방안)

  • Lee, Jong-Sik;Cho, Seung-Ho
    • Journal of the Korea institute for structural maintenance and inspection
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    • v.22 no.1
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    • pp.64-71
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    • 2018
  • Project Management Institute of America separates the types of risk with external risks and internal risks. The external risk is an uncontrollable risk in projects such as changes of policy and related systems, climate, natural disasters, exchange rates and so on. The internal risk is an existing risk in the project itself that is controllable items in the project. Technical risks in project management are cost, quality, time, safety and environment. Therefore, both the external and internal risks should be managed to perform the construction project successfully. In particular, we can secure the quality and safety of facilities through the technical risk management. The importance of potential risk management has been emerging as a major interest and the lack of risk management delays projects and increases construction costs with negative effects of the building safety since the complex building, which is composed of a great number of facilities, consists of many project units and there are conflicts between various participants and stake-holders. This study presents the ways of establishing risk management processes to ensure the safety of the complex building. To that end, establishing procedure of risk management processes is presented and types of risk and factors in construction projects and counter strategies are presented as available risk information on the stages.

Risk Assessment of the Accident Place Types Considering the Coastal Activity Time (연안활동시간을 고려한 장소유형별 위험도 평가)

  • Seo, Heui Jung;Park, Seon Jung;Park, Seol Hwa;Park, Seung Min
    • Journal of Korean Society of Coastal and Ocean Engineers
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    • v.34 no.5
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    • pp.144-155
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    • 2022
  • The Korea Coast Guard evaluates the risk of major coastal activity places to prevent coastal accidents, and patrols and manages them based on that, but it is not responding properly to the continuously increasing number of coastal accidents. The reason for this is that, despite the gradual expansion of coastal activity places, there is a lack of manpower to manage and supervise them, resulting in blind spots in coastal accident safety management. Therefore, in order to solve this problem, it is necessary to prepare more efficient and effective measures that check and supplement the current coastal safety management system. Coastal accidents show different characteristics of accident causes and places due to differences in the activity characteristics of users according to time. As a result of analyzing coastal accident data (2017~2021), the frequency of daytime accidents is high in the case of sea rock, beach, and offshore, where family leisure activities are frequent. In the case of wharf, tidal flat and bridge, where accidents due to drinking, disorientation, and suicide mainly occur, the frequency of accidents at night is high. In addition, there were more accidents on weekends when the number of users increased compared to weekdays. This trend indicates that the user's temporal activity characteristics must be reflected in the risk assessment of coastal activity places. Therefore, in this study, based on the case of coastal accidents, the characteristics of accidents at coastal activity places according to time were identified, and the criteria were presented for risk evaluation by grading them. It is expected that it will be possible to lay the foundation for reducing coastal accidents by efficiently managing and supervising coastal activity places over time using the presented evaluation criteria.

A Basic Study on the Railway Safety Management Based on Risk Assessment Approach (위험도 평가기법을 적용한 철도시스템의 안전관리)

  • Kim Sang Am;Wang Jong Bae;Kwak Sang Log;Lee Dong Ha
    • Proceedings of the KSR Conference
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    • 2003.10b
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    • pp.223-228
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    • 2003
  • Risk Management does not mean accepting a risk but having a good grasp of, eliminating and controling the exact causes of known hazards. Good safety management plan or system for the safety of any systems need to include the procedures about standing safety goals, related technical information, time schedule, audit programs, etc at least. In this paper the summeries on general risk assessment techniques and the examples of risk assessment system and railway risk management strategies used in UK, Australia and Canada are introduced, and applicable establishment procedures for domestic railway industries are proposed.

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Pesticide Risk and Benefit Assessment

  • Birtley, Robin D.N.
    • Korean Journal of Weed Science
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    • v.13 no.4
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    • pp.195-202
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    • 1993
  • The benefits of pesticides in improving the food quantity and quality requirements for an increasing world population are significant, and they can be described in agronomic, economic and social terms. The risks are assessed from the hazards which are likely to occur in practice ; the hazards are defined by the toxicity of the pesticide to non-target organisms at various exposure levels. There are ways of reducing the risks (mainly by reducing exposure in practice) and improving the benefits of pesticides ; these are known as risk management and benefit management respectively. The overall risk-benefit assessment is facilitated if each component can be expressed in financial terms, but it must be made nationally or locally on a sound technical basis against the prevailing agronomic, socio-economic and political circumstances. Paraquat is used to illustrate the risk-benefit assessment process in general terms, and the conclusion is that the benefits greatly outweigh the risks. It is important to keep the risks of pesticides in perspective with those associated with other naturally occurring chemicals in our diet and with other everyday aspects of life. In an overall context, the pesticide risk is small.

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Development of Risk-Based Inspection(RBI) Technology for LNG Plant Based on API RP581 Code (API RP 581 Code를 기반으로한 LNG 플랜트의 Risk-Based Inspection(RBI) 기술 개발)

  • Choi, Song-Chun;Choi, Jae-Boong;Hawang, In-Ju
    • Corrosion Science and Technology
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    • v.11 no.5
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    • pp.179-183
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    • 2012
  • As one of promising solutions to overcome high oil price and energy crisis, the construction market of high value-added LNG plants is spotlighted world widely. The purpose of this study is to introduce LNG-RBI system to develop risk assessment technology with RAM(Reliability, Availability, Maintainability) modules against overseas monopolization. After analyzing relevant specific features and their technical levels, risk assessment program, non-destructive reliability evaluation strategy and safety criteria unification class are derived as core technologies. These IT-based convergence technologies can be used for enhancement of LNG plant efficiency, in which the modular parts are related to a system with artificial optimized algorithms as well as diverse databases of facility inspection and diagnosis fields.

A Study on the Key Performance Factors of Passenger Airbag and Injury Risk Prediction Technique Development (동승석 에어백 핵심 성능 인자 및 상해위험도 예측 기법 개발에 대한 연구)

  • Park, Dongkyou
    • Transactions of the Korean Society of Automotive Engineers
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    • v.21 no.5
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    • pp.130-135
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    • 2013
  • Until now, passenger airbag design is based on the referred car design and many repetitive crash tests have been done to meet the crash performance. In this paper, it was suggested a new design process of passenger airbag. First, key performance factors were determined by analyzing the injury risk effectiveness of each performance factor. And it was made a relationship between injury risk and performance factor by using the response surface model. By using this one, it can be predicted the injury risk of head and neck. Predicted injury risk of optimal design was obtained through this injury risk prediction model and it was verified by FE analysis result within 18% error of head and 9% error of neck. It was shown that a target crash performance can be met by controlling the key performance factors only.

Earthquake hazard and risk assessment of a typical Natural Gas Combined Cycle Power Plant (NGCCPP) control building

  • A. Can Zulfikar;Seyhan Okuyan Akcan;Ali Yesilyurt;Murat Eroz;Tolga Cimili
    • Geomechanics and Engineering
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    • v.35 no.6
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    • pp.581-591
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    • 2023
  • North Anatolian Fault Zone is tectonically active with recent earthquakes (Mw7.6 1999-Kocaeli and Mw7.2 1999-Düzce earthquakes) and it passes through Marmara region, which is highly industrialized, densely populated and economically important part of Turkey. Many power plants, located in Marmara region, are exposed to high seismic hazard. In this study, open source OpenQuake software has been used for the probabilistic earthquake hazard analysis of Marmara region and risk assessment for the specified energy facility. The SHARE project seismic zonation model has been used in the analysis with the regional sources, NGA GMPEs and site model logic trees. The earthquake hazard results have been compared with the former and existing earthquake resistant design regulations in Turkey, TSC 2007 and TBSCD 2018. In the scope of the study, the seismic hazard assessment for a typical natural gas combined cycle power plant located in Marmara region has been achieved. The seismic risk assessment has been accomplished for a typical control building located in the power plant using obtained seismic hazard results. The structural and non-structural fragility functions and a consequence model have been used in the seismic risk assessment. Based on the seismic hazard level with a 2% probability of exceedance in 50 years, considered for especially these type of critical structures, the ratios of structural and non-structural loss to the total building cost were obtained as 8.8% and 45.7%, respectively. The results of the study enable the practical seismic risk assessment of the critical facility located on different regions.

A Study on the Strategies for Risk Management and the Extension of Expertise Considering the Types of Risk (위험의 유형에 따른 위험관리의 전략과 전문성의 확장에 대한 연구)

  • Choi, Kyung-Hee;Song, Sung-Soo
    • Journal of Engineering Education Research
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    • v.13 no.4
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    • pp.70-76
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    • 2010
  • This paper tries the systematic approach to risk which is a major theme in engineering ethics utilizing science and technology studies. The types of risk can be classified as technical risk, methodological risk, epistemological risk by the degree of uncertainty. The strategies for risk management can be assorted to applied science strategy, professional consultancy strategy, post-normal science strategy. These types and strategies of risk request different kinds of expertise such as technocratic expertise, interactive expertise, democratic expertise. This paper can not only contribute to complement and extend engineering ethics education but also be linked with the goals of engineering education in general.

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