• 제목/요약/키워드: tcdd

검색결과 224건 처리시간 0.029초

EFFECT OF OCTYLPHENOL ON THE TCDD STIMULATED CYP1A1 EXPRESSION

  • Joung, Ki-Eun;Kim, Yeo-Woon;Sheen, Yhun-Yhong
    • 한국독성학회:학술대회논문집
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    • 한국독성학회 2001년도 International Symposium on Signal transduction in Toxicology
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    • pp.129-129
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    • 2001

  • Alkylphenol ethoxylates have been used extensively as nonionic surfactants in industrial processing, household and institutional cleaning products. They are apparently degraded microbially to alkylphenol. Alkylphenol has been shown to possess estrogenic properties and, therefore, is an 'endocrine disrupter' that has significantly influence on sexual and reproductive development.(omitted)

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Inhibitory Effect of Octylphenol on the TCDD Induced CYPlAl Expression

  • Joung, Ki-Eun;Kim, Yeo-Woon;Sheen, Yhun-Yhong
    • 한국환경독성학회:학술대회논문집
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    • 한국환경독성학회 2001년도 춘계심포지움 및 학술발표회
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    • pp.138-138
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    • 2001

  • Alkylphenol ethoxylates have been used extensively as nonionic surfactants in industrial processing, household and institutional cleaning products. They are apparently degraded microbially to alkylphenol. Alkylphenol has been shown to possess estrogenic properties and, therefore, is an 'endocrine disrupter' that has significantly influence on sexual and reproductive development. (omitted)

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Environmental Endocrine Disruptors and Endometriosis

  • K.E. Joung;Kim, J.S.;H.W. Song;Y.Y. Sheen;S.K. Hong;S.B. Kang;Kim, H.;S.I. Cho
    • 한국독성학회:학술대회논문집
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    • 한국독성학회 2003년도 춘계학술대회 논문집
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    • pp.62-63
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    • 2003

  • A case-control study was designed to determine the possible association between dioxin like compounds (such as TCDD, PCDDs, PCDFs, and PCBs) and the occurrence and severity of endometriosis using CALUX bioassay method.(omitted)

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COX-INHIBITORS DOWN-REGULATE Cyplal ACTIVITY IN C57BL/6 MOUSE AND Hepa I CELLS.

  • Syrie Bang;Kim, Ja-Young;Sheen, Yhun-Yhong
    • 한국독성학회:학술대회논문집
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    • 한국독성학회 2002년도 Current Trends in Toxicological Sciences
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    • pp.90-90
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    • 2002

  • In order to understand the mechanism of action of TCDD, we have examine the effect of COX-inhibitors on Cyp1a1 activity. We observed the effect of COX-inhibitor on EROD activity in C57BL/6 mouse in vovo. And we also evaluated the effect of COX-inhibitors on mouse cyp1a1 promoter activity in Hepa cell.(omitted)

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