• Title/Summary/Keyword: tcdd

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EFFECT OF OCTYLPHENOL ON THE TCDD STIMULATED CYP1A1 EXPRESSION

  • Joung, Ki-Eun;Kim, Yeo-Woon;Sheen, Yhun-Yhong
    • Proceedings of the Korean Society of Toxicology Conference
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    • 2001.05a
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    • pp.129-129
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    • 2001

  • Alkylphenol ethoxylates have been used extensively as nonionic surfactants in industrial processing, household and institutional cleaning products. They are apparently degraded microbially to alkylphenol. Alkylphenol has been shown to possess estrogenic properties and, therefore, is an 'endocrine disrupter' that has significantly influence on sexual and reproductive development.(omitted)

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Inhibitory Effect of Octylphenol on the TCDD Induced CYPlAl Expression

  • Joung, Ki-Eun;Kim, Yeo-Woon;Sheen, Yhun-Yhong
    • Proceedings of the Korea Society of Environmental Toocicology Conference
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    • 2001.05a
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    • pp.138-138
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    • 2001

  • Alkylphenol ethoxylates have been used extensively as nonionic surfactants in industrial processing, household and institutional cleaning products. They are apparently degraded microbially to alkylphenol. Alkylphenol has been shown to possess estrogenic properties and, therefore, is an 'endocrine disrupter' that has significantly influence on sexual and reproductive development. (omitted)

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Environmental Endocrine Disruptors and Endometriosis

  • K.E. Joung;Kim, J.S.;H.W. Song;Y.Y. Sheen;S.K. Hong;S.B. Kang;Kim, H.;S.I. Cho
    • Proceedings of the Korean Society of Toxicology Conference
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    • 2003.05a
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    • pp.62-63
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    • 2003

  • A case-control study was designed to determine the possible association between dioxin like compounds (such as TCDD, PCDDs, PCDFs, and PCBs) and the occurrence and severity of endometriosis using CALUX bioassay method.(omitted)

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COX-INHIBITORS DOWN-REGULATE Cyplal ACTIVITY IN C57BL/6 MOUSE AND Hepa I CELLS.

  • Syrie Bang;Kim, Ja-Young;Sheen, Yhun-Yhong
    • Proceedings of the Korean Society of Toxicology Conference
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    • 2002.05a
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    • pp.90-90
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    • 2002

  • In order to understand the mechanism of action of TCDD, we have examine the effect of COX-inhibitors on Cyp1a1 activity. We observed the effect of COX-inhibitor on EROD activity in C57BL/6 mouse in vovo. And we also evaluated the effect of COX-inhibitors on mouse cyp1a1 promoter activity in Hepa cell.(omitted)

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