• Progress in Medical Physics
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• v.21 no.4
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• pp.360-366
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• 2010

To generate on-board digital tomosynthesis (DTS) for three-dimensionalimage-guided radiation therapy (IGRT) as an alternative to conventional portal imaging or on-board cone-beam computed tomography (CBCT), two clinical cases (liver and bladder) were selected to illustrate the capabilities of on-board DTS for IGRT. DTS images were generated from subsets of CBCT projection data (45, 162 projections) using half-fan mode scanning with a Feldkamp-type reconstruction algorithm. Digital tomosynthesis slices appeared similar to coincident CBCT planes and yielded substantially more anatomic information. Improved bony and soft-tissue visibility in DTS images is likely to improve target localization compared with radiographic verification techniques and might allow for daily localization of a soft-tissue target. Digital tomosynthesis might allow targeting of the treatment volume on the basis of daily localization.

• Progress in Medical Physics
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• v.7 no.2
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• pp.67-77
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• 1996

Purpose: To get a 3-D coordinates of intracranial target position was investicated in axial, sagittal and coronal magnetic resonance imaging with a preliminary experimented target localizer. Material and methods : In preliminal experiments, the localizer is made of engineering plastic to avoid the distrubance of magnetic field during the MR image scan. The MR localizer displayed the 9 points in three different axial tomogram. The bright signal of localizer was obtjained from 0.1～0.3％ of paramagnetic gadolinium/DTPA solution in T1WI or T2WI. In this study, the 3-D position of virtual targets were examined from three different axial MR images and the streotactic position was compared to that of BRW stereotactic system in CT scan with same targets. Results: This study provided the actual target position could be obtained from single scan with MRI localizer which has inverse N-typed 9 bars. This experiment was accomplished with shimming test for detection of image distortion in MR image. However we have not found the image distortion in axial scan. The maximum error of target positions showed 1.0 mm in axial, 1.3 mm for sagittal and 1.7 mm for coronal image, respectivelly. The target localization in MR localizer was investicated with spherical virtual target in skull cadaver. Furthermore, the target position was confirmed with CRW stereotactic system showed a 1.3 mm in discrepancy. Summary : The intracranial target position was determined within 1.7 mm of discrepancy with designed MR localizer. We found the target position from axial image has more small discrepancy than that of sagittal and coronal image.

• Journal of the Institute of Electronics Engineers of Korea SC
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• v.47 no.3
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• pp.56-62
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• 2010

Weakly electric fish uses active sensing to detect the distortion of self-generated electric field in the underwater environments. The active electrolocation makes it possible to identify target objects from the surroundings without vision in the dark sea. Weakly electric fish have many electroreceptors over the whole body surface of electric fish, and sensor readings from a collection of electroreceptors are represented as an electric image. Many researchers have worked on finding features in the electric image to know how the weakly electric fish identify the target object. In this paper, we suggest a new mechanism of how the electrolocation can recognize a given target object among object plants. This approach is based on the differential components of the electric image, and has a potential to be applied to the underwater robotic system for object localization.

• BMB Reports
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• v.39 no.6
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• pp.709-716
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• 2006

Mammalian polo-like kinase 1 (Plk1) acts at various stages in early and late mitosis. Plk1 localizes at the centrosome and maintains this position through mitosis. Thereafter Plk1 moves to the kinetochore and midbody region, important sites during chromosome separation and cytokinesis. The catalytic domain of Plk1 is in the N-terminus region, whereas the non-catalytic region in the C-terminus of Plk1 has a conserved motif, named the Polobox. This motif is critical for Plk localization. EGFP proteins fused with the N-terminus and C-terminus of Plk1 localize in the nucleus and centrosomes, respectively. The core sequences of the polo-box (50 amino acids) also localize in Plk1 target organelles. To screen for domain-specific target proteins of Plk1, we constructed an N-terminal domain and a tandem repeat polo-box motif, and used them as templates in a yeast two-hybrid screen. The HeLa cell cDNA library indicated several proteins including the centrosome/kinetochore components or regulators, to be characterized as positive clones. Through in vitro protein binding analyses, we confirmed an interaction between these proteins and Plk1. The data reported from this study indicate that the N- and C- termini of Plk1 may function through recruitment and/or activation of domain-specific target proteins in dividing cells. Additionally, tandem repeats of the conserved core motif of the polo-box are sufficient for targeting and may be useful as a centrosome/kinetochore-specific targeting peptide.

• The Journal of the Convergence on Culture Technology
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• v.7 no.1
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• pp.377-382
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• 2021

《Mu Yang Ai Hua, 牧羊哀話》 is known as the first Korean-sanctioned novel in the history of modern Chinese literature, and is famous for a novel created by the author himself visiting Korea and being inspired. The translation of 《牧羊哀話》 is constantly being re-translated (4 types). These translations also reflect the characteristics of each period, and the translation strategies used have their own characteristics. The results of the comparative analysis of the four types of translations in this study are as follows. The role A was published during the Japanese colonial period, and some parts were reduced and omitted according to the intent of the translator, and a foreignization translation strategy was used. B, C, and D have implemented content equivalence by utilizing many of the localization translation strategies, and added supplementary explanations in part to help readers understand. Since translation is a process of communication, it should not just convert the source text to the target text, but the target reader's response to the work should be the same as that of the reader. Therefore, translation must be able to understand the environment of the times and the readership, and it must use all possible methods to elicit the same emotion and empathy as the reader has read the original text. Therefore, translators need to use their nationalization and foreignization strategies at the same time based on their understanding of the target language and the politics, economy, history, culture, etc. of the destination country.

• Journal of Korean Neurosurgical Society
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• v.37 no.3
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• pp.197-200
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• 2005

Objective: Ultrasound can be used in the treatment of large intracerebral hematoma. The authors present our experiences with Ultrasound-guided catheter placement for lysis and drainage of ganglionic hematoma, with emphasis on technical aspects. Methods: The authors applied real-time ultrasonography for the aspiration of intracerebral hematoma in 6cases. Ultrasound-guided aspiration via a burrhole was performed under local anesthesia. We selected a temporal entry point instead of the frequently used precoronal approach in ganglionic hematoma. A burrhole was made 4 to 6cm posterior from posterior border of frontal process of the zygomatic bone at the level of 4 to 5cm above the external auditory meatus. Results: In all patients, the catheter was placed accurately into the hematoma target. All patients were irrigated with urokinase once to three times a day. The catheter could be removed within two or three days. The mean hematoma volume was reduced from initially 32mL to 5mL in an average of two days. There were no intraoperative complications related to the use of real-time ultrasonography and no postoperative infections were noted. Conclusion: Ultrasound allows an easy and precise localization of the hematoma and the distance from the surface to the target can be calculated. Ultrasound-guided catheter placement for fibrinolysis and hematoma drainage is a simple and safe procedure.

• Proceedings of the KAIS Fall Conference
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• 2009.12a
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• pp.295-298
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• 2009

다중 표적을 감시하는 무선 센서 네트워크에서 다중 표적이 서로 교차하게 될 때 각각의 표적을 분리하는 문제는 표적의 추적, 탐지, 식별 등의 분야에서 매우 중요하다. 기존의 무선 센서 네트워크에서는 에너지 기반의 기법을 사용하기 때문에 다중 표적의 위치를 추정할 수 없거나, 기지국에서의 원 신호 분석 방법을 통해 표적의 종류를 식별하여 각각의 표적을 분리한다. 후자의 방법은 무선 센서 노드의 통신량과 연산량을 증가시켜 센서 노드의 생존 시간이 짧아지는 단점이 있고, 표적 분리까지 걸리는 시간으로 인해 실시간 처리가 어렵다. 본 논문에서는 무선 센서 노드에서 웨이블릿 변환을 이용한 특징을 추출하고 이를 이용해 다중 표적이 센서 영역 내에서 교차하게 될 때 표적을 분리하는 방법을 제안한다. 제안된 방법은 웨이블릿 상수의 주파수 정보를 이용하여 적은 연산으로 표적을 분리한다.

• Korean Journal of Veterinary Pathology
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• v.6 no.1
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• pp.1-5
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• 2002

A1celaphine herpesvirus 1 (AHV-1) is a causative agent of malignant catarrhal fever which is a fatal and a lymphoproliferative syndrome. AHV-1 is a gamma herpesvirus, which induces frequent latent infection and often difficult to detect its antigens or specific nucleic acids because of its low viral copies in the infected tissues. A new method, in situ PCR, is developed for the detection of AHV-1 nucleic acid in this study. Target sequences of AHV-1 open reading frame 50 gene were detected within AHV-1 infected MDBK cells. As compare with other molecular biological methods for the detection of AHV-1, in situ PCR was found to be more sensitive than in situ hybridization and to be less sensitive than nested PCR. However, nested PCR cannot afford to observe and differentiate AHV-1 infected cells. In situ PCR amplifies a target sequence within cells that can be visualized microscopically with increased sensitivity compared to detection by in situ hybridization. In situ PCR has wide applications for sensitive localization of low copy AHV-1 viral sequences within cells to investigate the role of viruses in a variety of clinical conditions and also provide the rapid, sensitive, and specific detection of AHV-1 infection.

• The Journal of the Acoustical Society of Korea
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• v.37 no.3
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• pp.139-146
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• 2018

Monostatic sonar systems localize targets using the time information of pulse transmission and receipt. Whereas, in asynchronous bistatic sonar systems, receivers need to detect direct blast to localize targets, since a source doesn't share pulse information with receivers. In this paper, we propose a direct blast detection algorithm, which estimates PRI (Pulse Repetition Interval) of direct blast and adaptive thresholds. Experimental results show the proposed algorithm has robust direct blast detection performance in the environment where strong background noise and target signal exist.

• Journal of the Korea Institute of Military Science and Technology
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• v.5 no.1
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• pp.59-64
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• 2002

Passive sonar system forms the various beams in any desired directions to obtain the improvement in Signal-to-Noise(S/N) ratio, bearing detection and localization of targets, and the attenuation of interferences from other directions. Detection of modern underwater targets is becoming increasingly difficult as noise reduction technology leads to considerably low-level acoustic emissions. Therefore, the improvement of beamforming is very important to detect modern underwater targets at the long range in the complex environmental sea. Also, to react to the fast attack mobiles such as torpedoes, port and starboard discrimination is required to be performed very quickly. In this paper, we proposed the implementation of omnidirectional target bearing detector without port and starboard ambiguity to detect effectively the low-level underwater targets. The port and starboard discrimination is performed by cardioid processing and the improvement of beamforming utilizes the cross correlation matrix of individual hydrophone pairs of linear array sensors. The sea test result shows that the system implemented is good for the detection of the low-level underwater targets.