• Journal of the Korea Institute of Military Science and Technology
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• v.16 no.3
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• pp.340-347
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• 2013

Weapon effect is a key issue throughout the life cycle of weapon systems. Only when weapon effect is considered properly, Effects Based Operation(EBO), Effects Based Acquisition(EBA), and Effects Based Development(EBD) could be possible. Because the transfer of weapon effect technologies is restricted in most foreign counties, independent development is necessary. In this paper, framework of weapon effects calculator for hardened targets is proposed to meet the own development needs. It is designed focusing on running time, validation and expandibility by adoption of modular architecture. Required technologies for each module are identified, and unclassified ones are summarized.

• Bulletin of the Korean Space Science Society
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• 2008.10a
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• pp.31.4-32
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• 2008

The microwave instruments are used many areas of the space remote sensing and space science applications. The imaging radar of synthetic aperture radar (SAR) is well known microwave radar sensor for earth surface and ocean research. Unlike radar, microwave radiometer is passive instrument and it measures the emission energy of target, i.e. brightness temperature BT, from earth surface and atmosphere. From measured BT, the geophysical data like cloud liquid water, water vapor, sea surface temperature, surface permittivity can be retrieved. In this paper, the radiometer characteristics, system configuration and principle of BT measurement are described. Also the radiometer instruments TRMM, GPM, SMOS for earth climate, and ocean salinity research are introduce. As first korean microwave payload on STSAT-2, the DREAM (Dual-channels Radiometer for Earth and Atmosphere Monitoring) is described the mission, system configuration and operation plan for life time of two years. The main issues of DREAM unlike other spaceborne radiometers, will be addressed. The calibration is the one of main issues of DREAM mission and how it contribute on the space borne radiometer. In conclusion, the radiometer instrument to space science application will be considered.

• KEPCO Journal on Electric Power and Energy
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• v.3 no.2
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• pp.119-125
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• 2017

Regarding the implementation of ROMM project (Rehabilitation, Operation, Maintenance & Management), which is one of overseas development projects, it is very important to diagnose the exact current status of aged thermal power plant. However, when people visit the power plant for the purpose of prediagnosis to implement the ROMM project, most target power plants for diagnosis, in general, are under operation. This can be a big interference factor to diagnose the exact current status of power plants. Therefore, in order to solve such interference factor, based on the 30 years of know-how in the field, the present study has developed a regression curve for a simple life time assessment and the calculation of rehabilitation cost that may be used as a reference relatively for the quantitative diagnosis on the status of a relevant power plant even during the operation of the power plant.

• Biomolecules & Therapeutics
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• v.12 no.3
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• pp.145-150
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• 2004

Inflammation is a frequent radiation-induced reaction following therapeutic irradiation. Treatment of human umbilical endothelial cells (HUVEC) with ${\gamma}$-irradiation (${\gamma}$IR) induces the expression of adhesion proteins such as intercellular adhesion molecule-1 (ICAM-1), vascular cell adhesion molecule-1 (VCAM-1), and E-selectin. Since the upregulation of these proteins on endothelial cell Surface has been known to be associated with inflammation, interfering with the expression of adhesion molecules is an important therapeutic target. In the present study, we demonstrate that vitamin C inhibits ${\gamma}$IR induced expression of ICAM-1, VCAM-1, and E-selectin on HUVEC in a dose- and time dependent manner. Vitamin C a1so inhibited the production of Nitric oxide (NO) induced by ${\gamma}$IR. These data suggest that vitamin C has therapeutic potential for the treatment of various inflammatory disorder associated with an increase of endothelial leukocyte adhesion molecules.

• Agribusiness and Information Management
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• v.3 no.2
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• pp.17-32
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• 2011

Peru is South America's third largest country and enjoys an enormous amount of natural resources. However, However, very few business studies on Peruvian agriculture have been presented. The objectives of this study are to introduce the general status of Peruvian agriculture to Korean business circles and to promote agricultural business opportunities in Korea and Peru. Secondary data related to Peruvian agriculture are collected and analyzed to understand the current situation of Peruvian agriculture and to suggest an outlook for business opportunities. Findings show that Peru will be a lucrative market for Korean agri-business to target in the near future and it is time for a proactive advance in agriculture by Korean business.

• Journal of Intelligence and Information Systems
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• v.3 no.2
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• pp.33-55
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• 1997

A data model is a diagram that describes the properties of different categories of data and the associations among them within a business or information system. In spite of its importance and usefulness, data modeling activity requires not only a lot of time and effort but also extensive experience and expertise. The data models for similar business areas are analogous to one another. Therefore, it is reasonable to reuse the already-developed data models if the target business area is similar to what we have already analyzed before. In this research, we develop a case-based reasoning system for data model reuse, which we shall call CB-DM Reuser (Case-Based Data Model Reuser). CB-DM Reuse consists of four subsystems : the graphic user interface to interact with end user, the data model management system to build new data model, the case base to store the past data models, and the knowledge base to store data modeling and data model reusing knowledge. We present the functionality of CB-DM Reuser and show how it works on real-life a, pp.ication.

• Korean Journal of Pharmacognosy
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• v.50 no.4
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• pp.260-271
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• 2019

This study aimed to evaluate the safety of Oplopanax elatus (Nakai) Nakai hydrothermal extract powder. It was conducted using male and female Sprague-Dawley (SD) rats. The test group was established with dose of 500 (low-dosage group), 1,000 (medium- dosage group), and 2,000 (high- dosage group) mg/day. These are investigated that number of dead animals, general symptoms, weight changes, food consumption, ophthalmological examination, urinalysis, urine volume, hematological values, plasma coagulation time values, serum biochemical values, absolute organ weight, relative organ weight and histopathological finding during the experiment. As a result of the above, toxicological changes were not observed. Therefore, the non-toxic content of Oplopanax elatus (Nakai) Nakai hydrothermal extract powder is determined to be 2,000 mg/kg/day, and target organ was not observed.

• The Journal of the Korea Contents Association
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• v.8 no.4
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• pp.39-47
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• 2008

This paper describes the life GIS(Geographic Information System) system that enables users to look up the final destination on a map automatically by setting up a random radius of threshold under the present user position. Various information systems based on the existing GIS have disadvantage that a search is difficult when the destination location is not clear. And it is inefficient that the processing time is delay due to a complex configuration and large amount of informations based on the target of special business supports. Therefore, this paper improves these problems and proposes the customized life GIS which is for the general user in the Flash(Action Script) environment. The customized life GIS confirms the detail items from search results, which is destinations fitting for a condition in the suitable radius of threshold from the present user position. And the user can look up the suitable final destination on a map easily using the customized information system. The result of this paper, which is based on the sample of the large unit locations, will be expected to be able to guide more detail, extensive and various informations.

• Molecules and Cells
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• v.38 no.3
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• pp.273-278
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• 2015

The induction of angiogenesis is a crucial step in tumor progression, and therefore, efficient inhibition of angiogenesis is considered a powerful strategy for the treatment of cancer. In the present study, we report that the lipophilic antimicrobial peptides from EML-CAP3, a new endophytic bacterial strain isolated from red pepper leaf (Capsicum annuum L.), exhibit potent antiangiogenic activity both in vitro and in vivo. The newly obtained antimicrobial peptides effectively inhibited the proliferation of human umbilical vein endothelial cells at subtoxic doses. Furthermore, the peptides suppressed the in vitro characteristics of angiogenesis such as endothelial cell invasion and tube formation stimulated by vascular endothelial growth factor, as well as neovascularization of the chorioallantoic membrane of growing chick embryos in vivo without showing cytotoxicity. Notably, the angiostatic peptides blocked tumor cell-induced angiogenesis by suppressing the expression levels of hypoxia-inducible $factor-1{\alpha}$ and its target gene, vascular endothelial growth factor (VEGF). To our knowledge, our findings demonstrate for the first time that the antimicrobial peptides from EML-CAP3 possess antiangiogenic potential and may thus be used for the treatment of hypervascularized tumors.

• Development and Reproduction
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• v.23 no.1
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• pp.35-42
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• 2019

Fish shows great difference in growth rate between individuals during larval development and early growth. This difference seriously reduces the production efficiency in fish culture. Growth hormone (GH)/Insulin-like growth factor 1 (IGF1) system is said to play some pivotal roles in fish growth. In this study, we investigated differences of GH, IGF1 and GHR gene expressions in juvenile red spotted grouper (Epinephelus akaara) with different growth performance. Red spotted groupers were reared under the same environmental condition (water temperature $24{\pm}1^{\circ}C$, natural light) for 96 days after hatching. They were divided into 3 groups by size (fast growing, middle growing and slow growing groups: FGG, MGG, and SGG, respectively). RNA was extracted from the brain, liver and muscle tissues from each group, and target gene expression was examined by real-time PCR. In the brain with pituitary gland, expression of GH gene in FGG was significantly higher than the expression in SGG, but the expression of IGF1 and GHR genes in the muscle was highest in SGG. Difference of GHR and IGF1 mRNA in the liver between groups with different growth performance was less clear than that in other tissues, although level of IGF1 mRNA was higher in SGG than in MGG. These results suggest that hormonal governing of growth is not the same in fast growing and slow growing fish, and size grading could cause a shift of hormonal state and growth pattern in this species.