• Journal of the Korean Vacuum Society
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• v.14 no.4
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• pp.245-251
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• 2005

A high performance dual rocking magnet sputtering gun has been developed. The rocking magnet sputtering gun introduces full-face erosion by rapidly rocking the magnet in the region where the high plasma density is maintained. The newly developed dual rocking magnet sputtering gun whose target utilization was 77 percent achieved high performance in quality in the view of target utilization and target life-time comparing to the existing magnetron sputtering gun. The PIC-MCC target erosion simulation has been performed simultaneously. Comparing experimental target erosion profiles with simulated target erosion profiles, the simulation could estimate the tendency of the target erosion profiles but could not estimate an exact target erosion profile. If the simulation were improved more precisely, the cost reduction for the development of the multiple rocking magnet sputtering gun would be expected.

• Environmental Mutagens and Carcinogens
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• v.22 no.4
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• pp.236-242
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• 2002

Using agarose-coupled methotrexate, we have successfully isolated two proteins, which have strong interactions with methotrexate. The two proteins were analyzed by Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry and identified as carbamoyl-phosphate synthetase 2 and phosphoribosylglycinamide formyltransferase, respectively. Interestingly, both of these two proteins are essential key enzymes in nucleotide biosynthetic pathways, like dihydrofolate reductase, a well-known methotrexate target. We confirmed the specificity of their interactions between methotrexate and two target proteins by the methods of competition binding assay, which were followed by western blotting using antibody against carbamoyl-phosphate synthetase 2 and phosphoribosylglycinamide formyltransferase, respectively. Moreover, we could observe that carbamoyl-phosphate synthetase 2 is overexpressed in methotrexate-resistant MOLT-3 cells comparing with control MOLT-3 cells. This result indicates that carbamoyl-phosphate synthetase 2 may be a novel target of methotrexate in cancer therapy. We propose that chemical proteomics can be a powerful technique to identify target proteins of a chemical.

• Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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• 2007.11a
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• pp.365-366
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• 2007

High quality cathode with high deposition rate of thin films and long target life time is required for manufacturing TFT-LCD and semiconductor. We developed WV(wide view) sputtering cathode with wide erosion area and high deposition rate. Ti thin film thickness variation in WV cathode is below 5% for 380 kWh target life time. Al thin film thickness using normal cathode is decreased about 20%. By using WV cathode, target using efficiency was improved 40%. in comparison with normal cathode.

• Journal of the Korean Wood Science and Technology
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• v.51 no.6
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• pp.493-508
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• 2023

Round timber materials of 600 mm length, cut from large-cross-section round timber of red pine (Pinus densiflora S. et Z.) of 450 mm width and 4.2 m length, were prepared as the target of kiln drying in this study. After treating the target materials through end sealing (ES), end sealing - kerfing (ES-K), lateral sealing - end sealing - boring (LS-ES-B), or lateral sealing - partial end sealing (LS-PES), the effects of the treatment on the incidence of drying defects were determined. The target materials with exposed lateral surface and sealed cross surface were steamed at the initial temperature of 65℃ above the official pest control temperature of 56℃, followed by kiln drying toward the final temperature of 75℃. The target materials with sealed lateral surfaces, on the other hand, were dried at the initial temperature of 90℃ at almost the maximum temperature of conventional kiln drying, as there is no risk of early check formation caused by surface moisture evaporation. The final temperature was set at approximately 100℃. The drying time, taken for the target materials with initial moisture content of 70%-80% to reach the target moisture content of 19%, varied across treatment conditions. The measured drying time was 1,146 hours (approximately 48 days) for the timber with sealed cross surface and 745 hours (approximately 31 days) for the timber with sealed lateral surface, until the moisture content reached the target level. The formation of surface checks could not be prevented in the control and ES groups, but a definite preventive effect was obtained for the LS-ES-B and LS-PES groups.

• 한국정보디스플레이학회:학술대회논문집
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• 2009.10a
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• pp.794-797
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• 2009

We manufactured a novel gas permeation thin film passivation by using inorganic Mg-Zn-F target which has better optical characteristics and high electronegativity. We fabricated targets in various composition ratio and formed about 200nm which is limited thickness of the flexible display. Applied to PLED device, the target which composed of $MgF_2$ and Zn at the ratio of 4:6, WVTR was reached the measurement limit of the equipment, $10^{-3}g/m^2{\cdot}day$ and the life time was increased 25 times better than PLED device which is non-passivation.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.11 no.3
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• pp.978-983
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• 2010

Acoustic target classification in wireless sensor network is important research at environmental surveillance, invasion surveillance, multiple target separation. General sensor node signal processing methods concentrated on received signal energy based target detection and received raw signal compression. The former is not suited to target classification because of almost every target information are lost except target energy. The latter bring down life-time of sensor node owing to high computational complexity and transmission energy. In this paper, we introduce an feature extraction algorithm for acoustic target classification in wireless sensor network which has time and frequency information. The proposed method extracts time information and de-noised target classification information using wavelet decomposition step. This method reduces communication energy by 28% of original signal and computational complexity.

• Journal of the Korean housing association
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• v.16 no.5
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• pp.67-74
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• 2005

The performance of building should be deteriorated with time while the building would maintain and manage the function and performance to get a living condition. For the efficient maintenance of the building, the repair cycle would be provided and applied during the service-life time. The service-life time of the building components would be needed to determine the repair time and the repair scope. The service-life time of the building components would be calculated with the 1st repair time and the recovery rate of the performance, considering the recovery rate after repaired. In this paper, the 1st repair time would be estimated with the normal probability distribution, choice probability and 3rd quadratic function. The recovery rate of the building components assumes various level according to the research target and utility area. The results of this study are as follows ; first, most of the components of the building work would range about 30 years in the service-life time and the components of the mechanical works range from 28 years to 37 years, those of the electrical works would be about 31 years.

• Asian-Australasian Journal of Animal Sciences
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• v.29 no.11
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• pp.1646-1652
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• 2016

Mammalian target of rapamycin complex 1 (mTORC1) is a central regulator of cell growth and metabolism and is sufficient to induce specific metabolic processes, including de novo lipid biosynthesis. Elongation of very-long-chain fatty acids 1 (ELOVL1) is a ubiquitously expressed gene and the product of which was thought to be associated with elongation of carbon (C) chain in fatty acids. In the present study, we examined the effects of rapamycin, a specific inhibitor of mTORC1, on ELOVL1 expression and docosahexaenoic acid (DHA, C22:6 n-3) synthesis in bovine mammary epithelial cells (BMECs). We found that rapamycin decreased the relative abundance of ELOVL1 mRNA, ELOVL1 expression and the level of DHA in a time-dependent manner. These data indicate that ELOVL1 expression and DHA synthesis are regulated by mTORC1 in BMECs.

• Magazine of the Korean Society of Agricultural Engineers
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• v.45 no.2
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• pp.35-44
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• 2003

A system reliability method is proposed to decide reliable serviceability of agricultural irrigation system. Even though reliability method is applied to real engineering situations involving actual life environments and maintaining costs, a number of Issues arise as a modeling and analysis level. This article use concepts that can be described the probability of failure with time variant and series-parallel system reliability analysis model. A proposed method use survivor function that can simulate a time-variant performance function for a lifetime before it is required essential maintenance or replacement to define a target probability of failure in agricultural irrigation canal. In the further study, it is required a relationship between a state of probability of failure and current serviceability to make the optimum repair strategy to maintain appropriate serviceability of an irrigation system.

• Proceedings of the KSME Conference
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• 2003.11a
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• pp.1127-1132
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• 2003

Suspension system of vehicle have enough endurance during its life time to protect passenger. Spring is one of major part of vehicle. Thus, a fatigue strength evaluation for leaf spring based on road load response was carried out. At first, strain of leaf spring is measured on the city condition and proving ground condition. And next, the damage analysis of road load response data was carried out. And fatigue test of leaf spring were also carried out. Based on -N life relation, fatigue life of leaf spring was evaluated at belgian mode, city mode and drawing test specification. After that, it is compared the design life of leaf spring and evaluated fatigue life by belgian mode, city mode and drawing test specification. From the above, the maximum load-fatigue life relation of leaf spring was defined by test. and new test target of belgian mode and city mode was proposed to accept design specification of leaf spring. It is expect that proposed test target can verify leaf spring fatigue endurance at specific road condition.