• Title/Summary/Keyword: taiwan

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Treatment Response Evaluation by Computed Tomography Pulmonary Vasculature Analysis in Patients With Chronic Thromboembolic Pulmonary Hypertension

  • Yu-Sen Huang;Zheng-Wei Chen;Wen-Jeng Lee;Cho-Kai Wu;Ping-Hung Kuo;Hsao-Hsun Hsu;Shu-Yu Tang;Cheng-Hsuan Tsai;Mao-Yuan Su;Chi-Lun Ko;Juey-Jen Hwang;Yen-Hung Lin;Yeun-Chung Chang
    • Korean Journal of Radiology
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    • v.24 no.4
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    • pp.349-361
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    • 2023
  • Objective: To quantitatively assess the pulmonary vasculature using non-contrast computed tomography (CT) in patients with chronic thromboembolic pulmonary hypertension (CTEPH) pre- and post-treatment and correlate CT-based parameters with right heart catheterization (RHC) hemodynamic and clinical parameters. Materials and Methods: A total of 30 patients with CTEPH (mean age, 57.9 years; 53% female) who received multimodal treatment, including riociguat for ≥ 16 weeks with or without balloon pulmonary angioplasty and underwent both non-contrast CT for pulmonary vasculature analysis and RHC pre- and post-treatment were included. The radiographic analysis included subpleural perfusion parameters, including blood volume in small vessels with a cross-sectional area ≤ 5 mm2 (BV5) and total blood vessel volume (TBV) in the lungs. The RHC parameters included mean pulmonary artery pressure (mPAP), pulmonary vascular resistance (PVR), and cardiac index (CI). Clinical parameters included the World Health Organization (WHO) functional class and 6-minute walking distance (6MWD). Results: The number, area, and density of the subpleural small vessels increased after treatment by 35.7% (P < 0.001), 13.3% (P = 0.028), and 39.3% (P < 0.001), respectively. The blood volume shifted from larger to smaller vessels, as indicated by an 11.3% increase in the BV5/TBV ratio (P = 0.042). The BV5/TBV ratio was negatively correlated with PVR (r = -0.26; P = 0.035) and positively correlated with CI (r = 0.33; P = 0.009). The percent change across treatment in the BV5/TBV ratio correlated with the percent change in mPAP (r = -0.56; P = 0.001), PVR (r = -0.64; P < 0.001), and CI (r = 0.28; P = 0.049). Furthermore, the BV5/TBV ratio was inversely associated with the WHO functional classes I-IV (P = 0.004) and positively associated with 6MWD (P = 0.013). Conclusion: Non-contrast CT measures could quantitatively assess changes in the pulmonary vasculature in response to treatment and were correlated with hemodynamic and clinical parameters.

US Aid and Taiwan

  • Lee, Wei-Chen;Chang, I-Min
    • Asian review of World Histories
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    • v.2 no.1
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    • pp.47-80
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    • 2014
  • After the outbreak of the Korean War on June 25, 1950, the US included the Republic of China on Taiwan (Taiwan hereafter) in its Asia-Pacific containment line, and restored the military and economic aid to Taiwan for the sake of regional security. The US aid to the countries along the Asia-Pacific defense line was not only in the form of supplying munitions, but also linked these countries together in an economic dimension. Taiwan is one of the 120 countries which had accepted US aid and also successfully moved from "dependence" to "independently sustained growth." This article will firstly review the historical background of US aid to Taiwan and related institutional development; secondly, this article will illustrate how Taiwan used US aid, and which economic sector the US aid affected; thirdly, it will trace the impact of US aid on Taiwan's foreign trade, and finally, to make a conclusion.

Taiwan Report on Quitline Activities

  • Hsu, Pei-Ting;Chang, Chia-Wen;Chang, Te-Chung
    • Asian Pacific Journal of Cancer Prevention
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    • v.17 no.sup2
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    • pp.11-18
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    • 2016
  • Aiming at reducing smoking population, Taiwan government adopted a successful smoking cessation quitline model from California Smokers' Helpline, commissioned a private non-profit organization-Teacher Chang Foundation, which was well-known for its quality telephone counseling service-to set up Asia's first quitline, Taiwan Smokers' Helpline (TSH) in 2003. The establishment of the quitline is a significant progress for tobacco control in Taiwan, as it built up a cooperative model with smoking cessation clinics to increase the quit rate through assisting smokers to overcome their psychological obstacles while quitting smoking.