• 한국ITS학회 논문지
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• 제11권1호
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• pp.72-85
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• 2012

현재, 차량 내에서 사용하는 대부분의 블루투스 핸즈프리 디바이스는 음성 통화, 발신자 식별번호 표시 및 SMS 메시지 표시 등의 전화 서비스 기능을 제공하고 있지만 인터넷 기반의 텍스트 데이터 디스플레이 기능은 지원하지 않고 있다. 최근 들어 차량에서도 SNS와 같은 인터넷 서비스 이용에 대한 요구가 증가하고 있어, 기존의 핸즈프리 기능 이외에도 인터넷 기반의 텍스트 데이터를 표시하는 기능의 개발이 필요하다. 제안하는 블루투스 디바이스 응용은 SNS 메시지 및 이메일 도착 알림 표시 등의 향상된 기능을 포함하며, 구현 플랫폼으로는 대부분의 SNS 응용 프로그램의 동작이 가능하고 소형 임베디드 디바이스에 탑재가 용이한 안드로이드 플랫폼을 사용한다. 제안하는 블루투스 디바이스와 연결되는 스마트폰 또는 태블릿 PC 역시 안드로이드 플랫폼 기반의 단말기이며, 단말 탑재 기능 모듈인 오디오-텍스트 게이트웨이는 안드로이드 앱 형태로 설계된다. 오디오-텍스트 게이트웨이 앱은 SNS 텍스트 데이터 수신시, 메시지 헤더 정보에서 제목, 발신자 정보 등을 추출하여 텍스트 데이터 형태로 ACL(Asynchronous Connection-Oriented) 링크를 통해 블루투스 디바이스로 전송하여 화면에 표시되도록 한다. 일반적으로 안드로이드 플랫폼에 탑재된 블루투스 핸즈프리 또는 헤드셋 프로파일은 오디오 게이트웨이의 기능만을 포함하고 있기 때문에 안드로이드 기반의 블루투스 디바이스에서는 음성 데이터의 스피커 출력이 불가능하다. 따라서 제안하는 블루투스 디바이스 응용은 블루투스 헤드셋 프로파일에서 일반적으로 사용되는 SCO(Synchronous Connection-Oriented) 링크를 통한 음성 데이터 전송 방식 대신에 ACL 링크를 통한 스트리밍 방식을 적용한다.

• 한국전통조경학회지
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• 제40권1호
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• pp.43-54
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• 2022

본 연구는 조계종 25교구 본산을 중심으로 한국 전통 사찰의 주요 법당 내 주련의 내용과 봉안된 불·보살과의 공간의 인식 양상을 살펴보기 위해 주련의 출전에 해당하는 고문헌과 공간배치도를 비교·분석하였으며, 도출된 결과를 요약하면 다음과 같다. 첫째, 사찰 봉안 제불(諸佛)의 분류 특징은 『대승기신론』의 기록을 바탕으로 체(體), 상(相), 용(用)에 따라 분류하여 설명이 가능하였다. 구체적으로 석가모니불은 '상(相)', 아미타불과 관세음보살은 '용(用)', 비로자나불은 '체(體)'에 상응하는 것으로 나타났다. 둘째, 주요 법당의 주련은 주존불과 협시불을 중심으로 각 봉안 불·보살의 서원(誓願)과 사상을 의미하는 것으로 나타났다. 셋째, 주련의 내용은 봉안한 주존불을 중심으로 각 주불이 항상 자재(自在)하고 존재하는 불국토를 상징하고 의미하는 것으로, 찬불(讚佛)의 내용으로 구성되었다. 넷째, 사찰의 각 주요 법당의 주련은 참방하는 구도자(求道者)들에게는 상구보리(上求菩提)의 내용과 중생들을 제도하는 주존불의 입장에서 하화중생(下化衆生)을 표현하여, 사찰의 각 공간이 '피고득락(避苦得樂)'으로 인식되고 있음을 확인할 수 있었다.

• 헤리티지:역사와 과학
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• 제44권4호
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• pp.86-111
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• 2011

완(?)은 밥이나 국 반찬 등을 담는 배식기로, 음식문화에 있어서 개인식기의 발달을 보여주는 대표적인 기종이다. 대개 $0.3{\sim}0.4{\ell}$가 다수를 이루며 연질(軟質)소성의 정선된 태토를 사용한 완의 제작은 크게 회전판 위에 원형의 점토판을 놓고 그 위로 점토띠를 쌓아올려 성형을 마무리하는 기본 방식(I)과 기본 성형은 동일하나 최후 단계에서 회전판에서 완을 떼어내어 도치시켜 저부를 정면하여 평저의 각을 없애는 새로운 방식(II) 두 가지가 확인된다. 전자는 동체-저부 경계면의 각이 살아있는 특징을 공유하면서도 다수의 점토띠로 제작해 심도가 깊게 제작한 경우(Ia)와 2조의 점토띠로 제작하고 구순이 뾰족하게 제작한 것(Ib)의 두 가지로 다시 나뉜다. 후자는 동체-저부경계면의 각을 없앤다는 공통점이 있지만 바닥에 점토를 덧대어 나선형으로 마무리하는 것(IIa)과 바닥에서 동체부까지 한 번에 깎기나, 물손질로 마감하는 것(IIb)의 두 가지로 나뉜다. Ib식과 II식은 중국자기 완(천발형)의 형태적 영향하에 제작된다. 연판문 청자완의 도입 이후에는 굽이 있거나 없더라도 내면이 둥글고 오목한 잔(盞)형태의 완이 새롭게 제작 사용되어진다. 이렇듯 백제완은 중국제 청자완의 모방형태가 다수 확인되고 있는데 백제인들의 중국제 물품에 대한 관심과 수요가 컸음을 보여준다. 중국 출토 기년명 자료와의 비교, 공반유물의 나열 등을 통해 볼 때 각 제작기법은 I식에서 II식으로 다시 연판문 청자완의 영향하에 오목한 잔(盞)형태로의 변천 양상이 확인되었다.

• 대한인간공학회지
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• 제36권5호
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• pp.545-557
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• 2017

Objective: The aim of this study was to find risk factors in cultivating ginseng based on risk assessments and suggest safety measures for main risks. Background: Safety education and training is one of the practical and effective methods to prevent occupational accidents and injuries. In agricultural sector, there are few contents of safety education as compared to other industries. Especially, farm work has different cultivation characteristics according to the crops, so it needs special education materials for each crop. Among the various types of crops, ginseng contains various risk factors due to its long cultivating period and unique environment. Therefore, safety education material specified for ginseng is necessary to improve ginseng farmers' safety. Method: Risk assessment for cultivating tasks of ginseng was carried out through data obtained from various methods (site survey, interview, literature survey). To improve objectivity, the risk assessment was applied with 3-criteria (researcher estimate, interview, previous research results). Finally, the three high-risk tasks were selected and safety measures for those tasks were provided. Results: Three tasks, such as 'Mounting, maintenance and removing supports', 'Pest control' and 'Harvest', were selected as risky tasks among total tasks. (1) In 'Mounting' and maintenance and removing supports', the farmers found to be exposed to the risks of musculoskeletal disorders and accidents related to operating the tablet machine. (2) In 'Pest control', agrichemical poisoning, musculoskeletal disorders and hyperthermia were main risks. Finally, (3) In 'Harvest', the farmers are mainly exposed to the possibility of accidents of agricultural machines and risks of musculoskeletal disorders. Thus, it needs to apply appropriate safety measures to those risky tasks, such as safety guidelines, convenience equipment, protective kit, and so on. Conclusion: This study can be used as basic data for agricultural safety and expected that it would be useful for further study. In addition, the results of the research will be produced in the form of animation, which will enhance the safety consciousness for aged farmers. Application: The result of this study can be used in developing safety education materials for ginseng farmers which is essential to prevent occupational accidents and injuries among ginseng farmers.

• 한국정보디스플레이학회:학술대회논문집
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• 한국정보디스플레이학회 2008년도 International Meeting on Information Display
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• pp.1261-1262
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• 2008

Laser-based crystallization techniques are ideally-suited for forming high-quality crystalline Si films on active-matrix display backplanes, because the highly-localized energy deposition allows for transformation of the as-deposited a-Si without damaging high-temperature-intolerant glass and plastic substrates. However, certain significant and non-trivial attributes must be satisfied for a particular method and implementation to be considered manufacturing-worthy. The crystallization process step must yield a Si microstructure that permits fabrication of thin-film transistors with sufficient uniformity and performance for the intended application and, the realization and implementation of the method must meet specific requirements of viability, robustness and economy in order to be accepted in mass production environments. In recent years, Low Temperature Polycrystalline Silicon (LTPS) has demonstrated its advantages through successful implementation in the application spaces that include highly-integrated active-matrix liquid-crystal displays (AMLCDs), cost competitive AMLCDs, and most recently, active-matrix organic light-emitting diode displays (AMOLEDs). In the mobile display market segment, LTPS continues to gain market share, as consumers demand mobile devices with higher display performance, longer battery life and reduced form factor. LTPS-based mobile displays have clearly demonstrated significant advantages in this regard. While the benefits of LTPS for mobile phones are well recognized, other mobile electronic applications such as portable multimedia players, tablet computers, ultra-mobile personal computers and notebook computers also stand to benefit from the performance and potential cost advantages offered by LTPS. Recently, significant efforts have been made to enable robust and cost-effective LTPS backplane manufacturing for AMOLED displays. The majority of the technical focus has been placed on ensuring the formation of extremely uniform poly-Si films. Although current commercially available AMOLED displays are aimed primarily at mobile applications, it is expected that continued development of the technology will soon lead to larger display sizes. Since LTPS backplanes are essentially required for AMOLED displays, LTPS manufacturing technology must be ready to scale the high degree of uniformity beyond the small and medium displays sizes. It is imperative for the manufacturers of LTPS crystallization equipment to ensure that the widespread adoption of the technology is not hindered by limitations of performance, uniformity or display size. In our presentation, we plan to present the state of the art in light sources and beam delivery systems used in high-volume manufacturing laser crystallization equipment. We will show that excimer-laser-based crystallization technologies are currently meeting the stringent requirements of AMOLED display fabrication, and are well positioned to meet the future demands for manufacturing these displays as well.

• 약학회지
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• 제37권5호
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• pp.511-519
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• 1993

The short and variabke transit of drug throught GI tracj and the inter-and intra-subject variations of the transit restrict the sustained drug absorption after oral adminstration. These restrictions may be solved by retaining the dosage forms in the stomach. Then the dosage form will act as a platform which releases the drug slowly and makes the GI absorption occur for a long time. In this study, as the platforms, PVP hydrogels were synthesized by chemical and y-irradiation method in the cylindrical test tube. The chemical method means the synthesis of the hydrogel by heating the mixed solution of N-vinyl-2-pyrrolidone [monomer], acrylated albumin [crosslinking agent], 2, 2'-agobis(2-methylpropionitrile) [initiator] and proxyphylline [drug] at $65^{\circ}C$ for 5 hr. The $\gamma$-irradiation method means the synthesis of the hydrogel by irradiation with $^{60}$ Co $\gamma$-ray of the mixed solution of the monomer, acrylated albumin, and flurbiprofen [drug] at room temperature with total 0.2 Mrad for 3 hr. Our intention is to design the hydrogel tablet (diameter : 1.20 cm, thickness : 0.60 cm) which swells in the gastric fluid after oral administration to such a size that passing through the pylorus could be inhibited during the period of drug release. After releasing drug, the hydrogel should be degraded by the enzymeatic digestion in the stomach, or by hydrolysis and eventually solubilized. Thus, in votro tests were performed to examine the factors that affect swelling and drug release from the PVP hydrogels. Experimental results show that the hydrogels swell to a size larger than the diameter of the pylorus(l.3$\pm$0.7 cm) and the hydrogel prepared by the chemical method is digested by pepsin. But the hydrogel prepared by the $\gamma$-irradiation method was not digested by the pepsin and just collapsed with time. Thus, the swelling of the hydrogel synthesized by $\gamma$-irradiation was independent albumin acrylation time and pepsin concentration. But drug content and radiation dose affected the swelling and drug release kinetics of the hydrogel. Drug release from the hydrigels was prolonged up to about 24 hr. Therefore, it was concluded that by adjusting these factors, the albumin-crosslinked PVP hydrogel synthesized by $\gamma$-irradiation method is expected to be retained in the stomach for up to 60hr and be a potential platform of drugs for long-term GI absorption.

• 동의신경정신과학회지
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• 제23권2호
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• pp.99-120
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• 2012

Objectives : The oriental medicine Jangwonhwan, a boiled extract of 12 medicinal herbs/mushrooms, has been prescribed to patients with cognitive dysfunction, as originally described in the Korean medical text, DonguiBogam(amnesia chapter). Recently, a modified formula of Jangwonhwan (LMK02-Jangwonhwan) consisting of seven medicinal plants/mushrooms, was shown to reduce the ${\beta}$-amyloid deposition in the brain of Tg-APPswe/PS1dE9 mouse model for Alzheimer's disease. The toxicity of LMK02-Jangwonhwan was investigated in SD rats, by a daily oral administration for 13 weeks and NOAEL(No observed adverse effect dose), a definite toxic dose and target organ, as well. Methods : Quality control of the tablet form of LMK02-Jangwonhwan was established by estimating the indicative components, Ginsenoside Rg3 of Red Ginseng and Decursin of Angelicagigas Nakai. The toxicity of LMK02-Jangwonhwan was investigated in 6 week old, specific pathogen free (SPF), Sprageu-Dawley rats by oral administration. Each test group consisted of 10 male and 10 female rats. The groups received doses of 500, 1,000 or 2,000 mg/kg/day of test substance for 13 weeks. The clinical signs, death rate, body weight, food consumption, ophthalmic examination, urinalysis, hematological and serum biochemistry, organ weight and pathological changes were examined and compared with those of the control group. Results : The 13-week repeated oral treatment doses didn't result in any specific symptoms or death. There were no significant changes in the rat's weight and food consumption. Further, ophthalmic examination, urinalysis, hematological, serum biochemistry test and organ weight revealed no significant differences. Conclusions : The no-observed-adverse-effect level(NOAEL) of LMK02 for male and female Sprague-Dawley rats was determined as 2,000mg/kg/day and the target organ wasn't confirmed. Because no significant adverse effects were observed, the target organ could not be determined.

• 동의생리병리학회지
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• 제24권6호
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• pp.1034-1041
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• 2010

The oriental medicine Jangwonhwan, which is a boiled extract of 12 medicinal herbs/mushroom, has been prescribed for patients with cognitive dysfunction and it is originally from the Korean medical text, DonguiBogam(amnesia chapter). Recently, a modified recipe of Jangwonhwan (LMK02-Jangwonhwan) consisting of seven medicinal plants/mushroom, was shown to reduce ${\beta}$-amyloid deposition in the brain of Tg-APPswe/PS1dE9 mouse model of Alzheimer disease. The toxicity of LMK02 was investigated in SD rats by oral repeated adminstration for 4 weeks and we tried to determine test does for 13 weeks repeated study. Quality control of tablet form of LMK02 was established by estimating indicative components, Ginsenoside Rg3 of Red Ginseng and Decursin of Angelicagigas Nakai. The toxicity of LMK02 was investigated in 6 weeks old specific pathogen free (SPF) Sprageu-Dawley rats by oral administration. Each test group were consist of 5 male and 5 female and they received doses of 500, 1,000 and 2,000 mg/kg/day of test substance for 4 weeks. The clinical signs, death rate, body weight, food consumption, ophthalmic examination, urinalysis, hematological and serum biochemistry, organ weight and pathological changes were examined and compared with those of control group. Urinalysis : We observed increase of PRO(p<0.01), SG(p<0.01) in female rats of 1,000 mg/kg/day and 2,000 mg/kg/day(p<0.01). Also, we observed increase of pH and KET in female rats of 1,000 mg/kg/day(p<0.05) and of 2,000 mg/kg/day(p<0.01). WBC in female rats in 1,000 mg/kg/day and 2,000 mg/kg/day were on increase. Hematological test : We observed increase of MCV in male rats of 250 mg/kg/day. (p<0.05) Serum biochemistry test : We found increase of CHO in female rats of 2,000 mg/kg/day(p<0.05). During the experimental period, there were no animals dead or moribund. There were no treatment related changes of general symptom, food and water consumption, organ weight and autopsy According to the results of 4-week repeated dose range finding study, the highest dose was established as 1000 mg/kg for 13-week repeated dose toxicity study and we determined to put 2 more groups by common ratio two.

• 한국식품위생안전성학회지
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• 제22권1호
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• pp.15-22
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• 2007

건강기능식품은 인체에 유용한 기능성을 가진 원료나 성분을 사용하여 정제, 캅셀, 분말, 과립, 액상, 환등의 형태로 제조 가공한 식품을 말한다. 2004년 '건강기능식품에 관한 법률‘이 제정되었지만 아직은 시작단계이며 소비자의 피해나 섭취 후 부작용에 대한 문제도 많이 발생하고 있다. 건강기능식품 중 비교적 높은 부작용 발생 빈도를 보이는 건강기능식품의 주원료인 식물성 원료 14종 37개 품목과 알로에분말 제품 4개 품목을 대상으로 미생물 분석을 하였으며, PSL을 이용하여 알로에분말 제품의 방사선조사 가능성 여부를 알아보았다. 식물성 원료 총 14종 37개 품목에서 세균수는 $10^{3}-10^{6}\;CFU/g$ 검출되었으며, 대장균군은 검출한계(<10 CFU/g)에서 31개 품목에서 $10^{2}-10^{5}\;CFU/g$ 검출되었다. 식중독균은 E. coli와 Salmonella spp., Staph. aureus는 검출되지 않았으며, B. cereus는 8종 12개 품목에서 검출되었다. 알로에 분말제품 4개 품목 중 1개 품목에서만 세균수 $10^{4}\;CFU/g$, 대장균군수는 $10^{3}\;CFU/g$ 검출되었고, 식중독균은 검출되지 않았다. PSL을 이용하여 알로에 분말제품의 방사선조사 가능성을 monitoring한 결과, 알로에 분말제품은 4개 품목 중 positive 2개 품목, negative 1개 품목, intermediate 1개 품목이었다.

• Journal of Pharmaceutical Investigation
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• 제36권5호
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• pp.331-338
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• 2006

A rapid, selective and sensitive reverse-phase HPLC methods for the determination of atenolol and chlorthalidone in human serum and whole blood were validated, and applied to the pharmacokinetic study of atenolol and chlorthalidone combination therapy. Atenolol and an internal standard, pindolol, were extracted from human serum by liquid-liquid extraction, and analyzed on a $\mu$-Bondapak C18 $10-{\mu}$ column in a mobile phase of methanol-0.01 M potassium dihydrogenphosphate(30:70, v/v, adjusted to pH 3.5) and fluorescence detection(emission: 300 nm, excitation: 224 nm). Chlorthalidone and an internal standard, probenecid, were extracted form human whole blood by liquid-liquid extraction, and analyzed on a Luna C18 $5-{\mu}$ column in a mobile phase of acetonitrile containing 77% 0.01 M sodium acetate and UV detection at 214 nm. These analysis were performed at three different laboratories using the same quality control(QC) samples. The chromatograms showed good resolution, sensitivity, and no interference by human serum and whole blood, respectively. The methods showed linear responses over a concentration range of 10-1,000 ng/mL for atenolol and 0.05-20 ${\mu}g/mL$ for chlorthalidone, with correlation coefficients of greater than 0.999 at all the three laboratories. Intra- and inter-day assay precision and accuracy fulfilled international requirements. Stability studies(freeze-thaw, short-, long-term, extracted sample and stock solution) showed that atenolol and chlorthalidone were stable. The lower limit of quantitation of atenolol and chlorthalidone were 10 ng/mL and 0.05 ${\mu}g/mL$, respectively, which was sensitive enough for pharmacokinetic studies. These methods were applied to the pharmacokinetic study of atenolol and chlorthalidone in human volunteers following a single oral administration of Hyundai $Tenoretic^{\circledR}$ tablet(atenolol 50 mg and chlorthalidone 12.5 mg) at three different laboratories.