• Title/Summary/Keyword: t5

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STUDY ON THE RELATIONSHIP BETWEEN SEROTONIN SYSTEM AND PSYCHOPATHOLOGY IN TOURETTE'S DISORDER (Tourette씨병의 Serotonin계와 정신병리와의 상호관계에 관한 연구)

  • Cho, Soo-Churl;Shin, Yun-O;Suh, Yoo-Hun
    • Journal of the Korean Academy of Child and Adolescent Psychiatry
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    • v.7 no.1
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    • pp.77-91
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    • 1996
  • In order to elucidate the biological etiology and the effects of comorbidity on biological variables in tic disorders, plasma serotonin (5-hydroxlfryptamine, 5-HT) and 5-hydroxy- indoleacetic acid (5-HIAA) we.e measured in 87 tic disorders and 30 control subjects. The 87 tic disorder were composed of 45 Tourette's disorder(TS), 22 chronic motor tic disorders (CMT) and 20 transient tic disorders (TTD). Among these patients,43 patients were pure tic disorder (PT), 28 subject also had attention deficit hyperactivity disorder (T+ADHD) and 16 subjects had obsessive compulsive disorders (T+ OCD) as comorbid disorders. The results are summarized as follows : 1) Plasma 5-HT levels showed significant positive correlations with plasma 5-HIAA levels (Pennon r=0.77, p<0.05). 2) Plasma 5-HT and 5-HIAA levels showed no significant correlation with age in tic disorders. 3) Plasma 5-HIAA and 5-HT levels showed no significant correlations with age in control subjects. 4) There was significant difference in plasma 5-HT levels among TS, CMT, TTD and control groups (ANOVA F=34.48, df=3, 113, p<0.01), and post-hoc test using Scheffe method showed significant differences between control and TS, control and CMT, control and ITD groups. But, post-hoc test showed no significant differences between TS and CMT, TS and TTD, CMT and TTD groups. 5) There was significant difference in plasma 5-HIAA levels among TS, CMT, TTD and control groups (ANOVA F=26.48, df=3, 113, p<0.01), and post-hoc test using Scheffe method showed significant differences between control and TS, control and CMT, control and TTD groups. But, post-hoc test showed no significant differences between TS and CMT, TS and TTD, CMT and TID groups.f) There was significant difference in plasma 5-HT and 5-HIAA levels among PT, T+ADHD, T+OCD and contol groups (ANOVA 5-HT, F=37.59, df=3, 113, p<0.01, 5-HIAA, F=27.37, df=3, 113, p<0.01), and post-hoc test using Scheffe method showed signiscant differences between control and PT, control and T+ADHD and control and T+OCB. But, post-hoc test showed no significant differences between PT and T+ADHD, PT and T+ OCD and T+ADHD and T+ OCD. These results show that decreased 5-HT and 5-HIAA levels may play a role in the genesis of tic disorders, but these findings have no significant correlations with the severity of tic disorders. And the comorbid disorders of tics may have minimal effects on the biochemical abnormalities. Future studies must be focused on the effects of serotonin agonists and antagonists on tic disorders and molecular biological methodology may enhance to elucidate the mechanisms of these abnormal findings.

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The Price-discovery of Korean Bond Markets by US Treasury Bond Markets by US Treasury Bond Markets - The Start-up of Korean Bond Valuation System - (한국 채권현물시장에 대한 미국 채권현물시장의 가격발견기능 연구 - 채권시가평가제도 도입 전후를 중심으로 -)

  • Hong, Chung-Hyo;Moon, Gyu-Hyun
    • The Korean Journal of Financial Management
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    • v.21 no.2
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    • pp.125-151
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    • 2004
  • This study tests the price discovery from US Treasury bond markets to Korean bond markets using the daily returns of Korean bond data (CD, 3-year T-note, 5-year T-note, 5-year corporate note) and US treasury bond markets (3-month T-bill, 5-year T-note 10-year T-bond) from July 1, 1998 to December 31, 2003. For further research, we divide full data into two sub-samples on the basis of the start-up of bond valuation system in Korean bond market July 1, 2000, employing uni-variate AR(1)-GARCH(1,1)-M model. The main results are as follows. First the volatility spillover effects from US Treasury bond markets (3-month T-bill, 5-year T-note, 10-year T-bond) to Korean Treasury and Corporate bond markets (CD, 3-year T-note, 5-year T-note, 5-year corporate note) are significantly found at 1% confidence level. Second, the price discovery function from US bond markets to Korean bond markets in the sub-data of the pre-bond valuation system exists much stronger and more persistent than those of the post-bond valuation system. In particular, the role of 10-year T-bond compared with 3-month T-bill and 5-year T-note is outstanding. We imply these findings result from the international capital market integration which is accelerated by the broad opening of Korean capital market after 1997 Korean currency crisis and the development of telecommunication skill. In addition, these results are meaningful for bond investors who are in charge of capital asset pricing valuation, risk management, and international portfolio management.

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Improvement of Growth and Survival Rate in Larval and Juvenile Rockfish (Sebastes schlogeli) from Mother Fish in Vitellogenesis Injected with 3,5,35-triiodo-L-thyronine($T_3$) (난황형성기 모체내 3,5,35-triiodo-L-thyronine ($T_3$) 주사에 의한 조피볼락 자치어의 성장과 생존율 향상)

  • 강덕영;장영진
    • Journal of Aquaculture
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    • v.11 no.3
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    • pp.303-310
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    • 1998
  • The growth and survival rate of larvae and juveniles from female rockfish (Sebastes schlegeli) broodstock in vitellogenesis by injection of 3,5,3'-triiodo-L-thyronine $T_3$ with a dose of 20 mg/kg fish wt. were examined for 30 days and compared with sham-control fish injected dime-thyl sulfoxide and control fish. Larvae were fed with rotifers for first 5 days after parturition, rotifers and Artemia nauplii for next 10 days. And then, they were fed with Artemia nauplii and commercial diet. Growth of larvae and juveniles from maternal $T_3$injection was significantly faster than that of two controls, nevertheless, the condition factor was lower than that of controls. The whole body proximate analyses indicated that there were significant effects of $T_3$ injection on protein and lipid, but no significant on moisture and ash contents. Survival rate of the fish from maternal $T_3$injection was significantly higher than that of fish from the two controls. These results indicate that thyroid hormone supplements appear to confer a distinct advantage to larval and juvenile rockfish in early, fragile development stage.

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Effect of Herbal Chokong Pill on the Microstructure of Liver Cell in Rats Fed High Fat Diet (고지방식이 섭식 횐쥐의 간조직에 미치는 한방초콩환의 영향)

  • Park, Chan-Sung;Kim, Dong-Han;Kim, Mi-Lim
    • Journal of Life Science
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    • v.18 no.2
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    • pp.200-205
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    • 2008
  • The purpose of this study is to investigate the effects of the herbal Chokong pill (hereafter HCKP) on the liver cell and enzyme activities of serum in rat. HCKP were mixed with pickled black soybeans and five different kinds of medicinal herbs (Rhynchosia nulubilis, Glycyrrhiza uralensis, Zizyphus vulgaris, Atractylodes macrocephala K., Astragalus membranaceus and Cornus officinalis). Four groups of male Sprague-Dawley rats were fed by different diets for 9 weeks: normal diet (Nor), high-fat diet (HF), high-fat diet supplemented with 1% (T1) and 5% (T5) HCKP powder, respectively. Depending on the presence of HCKP in high fat diet, the activities of the blood serum GOT and GPT were decreased. GOT and GPT activities of T1 and T5 were decreased 6.1%, 17.8% and 25.4%, 32.4% compared with HF. On microstructure observing through the transmission electron microscope (TEM) of liver cell, in normal group, a normal large and clear nucleus, rough endoplasmic reticulum (RER) and mitochondria possessing well-defined double outer-limiting membranes were found. However, in HF, it was hard to observe the microstructures in cytoplasm, because of too many fat granules. It showed severely damaged cell, pyknotic nucleus, swollen disintegrating RER and mitochontria loosing the cristae. In T1, there were more repaired liver cells and less fat granules than HF. In T5, there were much less numbers and smaller size of the fat granules than T1, and the morphology was similar to normal cell.

Efficiency of Various Nutritional Sources to Improve Physical Properties of Saline-Sodic Soil

  • Noor-Us-Sabah, Noor-Us-Sabah;Sarwar, Ghulam;Ibrahim, Muhammad;Tahir, Mukkram Ali;Iftikhar, Yasir;Haider, Muhammad Sajjad;Han, Kyung-Hwa;Ha, Sang-Keun;Zhang, Yong-Seon
    • Korean Journal of Soil Science and Fertilizer
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    • v.45 no.1
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    • pp.93-97
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    • 2012
  • This study was conducted to evaluate the efficiency of various inorganic and organic materials to improve physical properties of soil. Saline sodic soil (saturation percentage = 40.36%, $EC_e=5.15dS\;m^{-1}$, $pH_s=8.70$, $SAR=18.84(m\;mol\;L^{-1})^{1/2}$, bulk density =$1.49Mg\;m^{-3}$) was collected, brought to wire house and filled in pots after laboratory analysis for various parameters. Different sources of organic nutrients like farm manure (FM), press mud, compost, poultry manure and sesbania green manure were analyzed for their chemical composition. The experiment comprised of 12 treatments replicated thrice; $T_1$: control (recommended NPK), $T_2:{\frac{1}{2}}$ recommended NPK, $T_3$: FM at 1.5% by soil weight, $T_4$: pressmud at 1.5% by soil weight, $T_5$: compost at 1.5% by soil weight, $T_6$: poultry manure at 1.5% by soil weight, $T_7$: sesbania green manure at 1.5% by soil weight, $T_8:T_2$ + FM at 0.75% by soil weight, $T_9:T_2$ + pressmud at 0.75% by soil weight, $T_{10}:T_2$ + compost at 0.75% by soil weight, $T_{11}:T_2$ + poultry manure at 0.75% by soil weight, $T_{12}:T_2$ + sesbania green manure at 0.75% by soil weight. These treatments were applied using completely randomized (CR) design and appropriate time was given to decompose these organic nutritional sources. Seeds of wheat cultivar Sahar-2006 were sown. After harvesting the wheat, soil samples were collected from each pot and analyzed for various physical properties like bulk density, porosity and saturation percentage. An improvement in physical properties (bulk density, porosity and saturation percentage) of soil was noticed with the application of various organic nutritional sources but role of compost alone ($T_5$) remained prominent.

A Study on the Driven and Analysis of T5 Application Circuits using a Characteristics of Piezoelectric Transformer (압전 변압기 특성을 이용한 T5급 응용회로 동작 및 해석에 관한 연구)

  • Lee, Hae-Chun;Lee, Chang-Goo
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.11 no.1
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    • pp.113-118
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    • 2010
  • In This Paper, at the PSPICE model is presented by Piezoelectric Transformer and CCFL and equivalent circuit of fluorescent light. Highly effective fluorescent light release for next generation is developed for 35W supremacy model three wave length T5 fluorescent lamps. Lighting a candle experiment of T5 fluorescent lamps is carried out by employing Piezoelectric Transformer power-factor improvement circuit and inverter. PLL method is used for supplying a correct frequency of Piezoelectric Transformer operating.

VL-KE-T5: A contrastive learning-based pre-trained model using image-language parallel data composed of Korean and English (VL-KE-T5: 한국어와 영어로 구성된 영상-언어 병렬 데이터를 이용한 대조학습 기반 사전학습모델 구축)

  • San Kim;Saim, Shin
    • Annual Conference on Human and Language Technology
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    • 2022.10a
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    • pp.337-342
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    • 2022
  • 본 논문은 한국어-영어 기반 영상-언어 모델인 VL-KE-T5를 소개한다. VL-KE-T5는 영상-텍스트 쌍으로 구성된 한국어와 영어 데이터 약 2천 3백만개를 이용하여 영상-언어 모델의 임베딩 벡터들을 정렬시킨 사전학습모델이며, 미세조정을 통하여 여러 영상-언어 작업에 활용할 할 수 있다. VL-KE-T5는 텍스트 기반 영상 검색 작업에서 높은 성능을 보였으나, 세세한 속성을 가진 여러 객체들의 나열이나 객체 간 관계를 포함한 텍스트 기반 영상 검색에서는 비교적 낮은 성능을 보였다.

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Construction of bilingually pre-trained language model from large-scaled Korean and English corpus (KE-T5: 한국어-영어 대용량 텍스트를 활용한 이중언어 사전학습기반 대형 언어모델 구축)

  • Shin, Saim;Kim, San;Seo, Hyeon-Tae
    • Annual Conference on Human and Language Technology
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    • 2021.10a
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    • pp.419-422
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    • 2021
  • 본 논문은 한국어와 영어 코퍼스 93GB를 활용하여 구축한 대형 사전학습기반 언어모델인 KE-T5를 소개한다. KE-T5는 한국어와 영어 어휘 64,000개를 포함하는 대규모의 언어모델로 다양한 한국어처리와 한국어와 영어를 모두 포함하는 번역 등의 복합언어 태스크에서도 높은 성능을 기대할 수 있다. KE-T5의 활용은 대규모의 언어모델을 기반으로 영어 수준의 복잡한 언어처리 태스크에 대한 연구들을 본격적으로 시작할 수 있는 기반을 마련하였다.

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Long-KE-T5: Korean-English Language model for Long Sequences (Long-KE-T5: 긴 맥락 파악이 가능한 한국어-영어 언어 모델 구축)

  • San Kim;Jinyea Jang;Minyoung Jeung;Saim Shin
    • Annual Conference on Human and Language Technology
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    • 2023.10a
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    • pp.168-170
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    • 2023
  • 이 논문에서는 7,400만개의 한국어, 영어 문서를 활용하여 최대 4,096개의 토큰을 입력으로하고 최대 1,024개의 토큰을 생성할 수 있도록 학습한 언어모델인 Long-KE-T5를 소개한다. Long-KE-T5는 문서에서 대표성이 높은 문장을 생성하도록 학습되었으며, 학습에 사용한 문서의 길이가 길기 때문에 긴 문맥이 필요한 태스크에 활용할 수 있다. Long-KE-T5는 다양한 한국어 벤치마크에서 높은 성능을 보였으며, 사전학습 모델링 방법이 텍스트 요약과 유사하기 때문에 문서 요약 태스크에서 기존 모델 대비 높은 성능을 보였다.

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Effects of Fruiting Productivity of Grifola frondosa Using Bottle Cultivation according to Different Substrate Composition (잎새버섯에서 배지조성이 병재배 자실체 생산성에 미치는 영향)

  • Kim, Jeong-Han;Jeon, Dae-Hoon;Kang, Young-Ju;Jeoung, Yun-Kyeoung;Lee, Yun-Hae;Chi, Jeong-Hyun
    • The Korean Journal of Mycology
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    • v.44 no.3
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    • pp.150-154
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    • 2016
  • To determine a favorable substrate formulation for Grifola frondosa, physicochemical conditions, culture properties, and yields according to various substrate formulations were investigated. Based on these analyses, T4 (80:5:15 ratio of oak sawdust to dried bean-curd refuse to corn husk) resulted in a shorter cultivation period and higher yields (weight of fresh mushrooms harvested at maturity) than those of other treatments. The physicochemical properties of T4 were pH 5.4, 2.4% crude fat contents, 54 C/N ratio, 74.3% porosity, and 0.26 g/cm3 bulk density. These results emphasize the importance of optimal substrate development on the production efficiency of G. frondosa mushrooms and have implications for commercial applications.