• 한국산업보건학회지
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• 제24권1호
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• pp.52-58
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• 2014

Objectives: Using laborers participating in the petrochemical factory turnaround process as subjects, this study aims to identify exposure to benzene in the air and examine the relationship between exposure and the excretion of urinary metabolites by measuring concentrations of urinary trans, trans-muconic acid (t,t-MA). Methods: A passive sampler was used to measure the level of benzene in the air. In order to analyze urinary metabolites, the urine of laborers participating in the turnaround process was collected twice daily, both before and after work. In addition, a survey was conducted on work factors and lifestyle habits as factors affecting the concentration of urinary metabolites. Results: During the survey period, benzene was detected in the samples from all workers, and its average concentration was $0.16{\pm}0.22ppm$. The average concentration of t,t-MA after work was $1.20{\pm}1.86mg/g$ creatinine, and the results of analyzing urinary metabolites concentration before and after work showed statistically significant differences(p=0.003). There was also a statistically significant correlation (r=0.52, p=0.002) between benzene in the air and the concentration of after-work urinary t,t-MA. Conclusions: During the turnaround process, the average benzene concentration in workers was $0.16{\pm}0.22ppm$, which was below the exposure limit. However, their average t,t-MA concentration was $1.20{\pm}1.86mg/g$ creatinine, which exceeded the exposure limit of 1mg/g creatinine. The characteristics of turnaround process work require considerations such as underestimating the passive sampler being used and the skin absorption of benzene, and there needs to be a simultaneous assessment of working environment measurements and biological monitoring.

• 자원환경지질
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• 제32권2호
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• pp.141-150
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• 1999

The granitic rocks are distributed in the northeastern Gyeongsang basin, and are subdivided into the Youngduk, Younghae, Jangsadong and Onjeong granite. Based on the chondrite normalized patterns of REE by primitive mantle, the Jangsadong granite is more negative Eu anomaly than other granites. On the patterns of trace and rare earcth elements normalized by primitive mantle, Sr, P, Nd, Sm and Ti contents of t도 Youngduk and Younghae granites are higher than those of Jangsadong and Onjeong granites. Based on K-Ar ages, the Youngduk granite is 166.5 Ma for biotite, Younghae granite is 158.7 to 178.0 Ma for hornblende, Jangsadong granite is 113.8 to 118.4 Ma for K-feldspar and hornblende, and Onjeong granite is 67.4 Ma for biotite. Thus, geochemical and geochronological results suggest two plutonic episodes :the Youngduk-Younghae granites and Jangsadong-Onjeong granites suggest two plutonic episodes : the Youngduk-Younghae granites and Jangsadong-Onjeong granites. Jurassic plutonism cooled faster than Cretacous plutonism in the study area.

• 천문학회지
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• 제34권4호
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• pp.321-323
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• 2001

Compressible, magnetohydrodynamic (MHD) turbulence in two dimension is studied through high-resolution, numerical simulations with the isothermal equation of state. First, hydrodynamic turbulence with Mach number $(M)_{rms}\;\~$1 is generated by enforcing a random force. Next, initial, uniform magnetic field of various strengths with Alfvenic Mach number Ma $\gg$ 1 is added. Then, the simulations are followed until MHD turbulence is fully developed. Such turbulence is expected to exist in a variety of astrophysical environments including clusters of galaxies. Although no dissipation is included explicitly in our simulations, truncation errors produce dissipation which induces numerical resistivity. It mimics a hyper-resistivity in our second-order accurate code. After saturation, the resulting flows are categorized as SF (strong field), WF (weak field), and VWF (very weak field) classes respectively, depending on the average magnetic field strength described with Alfvenic Mach number, $(Ma)_{rms}{\ge}1$, $(Ma)_{rms}{\~}1$, and $(Ma)_{rms}{\gg}1$. The characteristics of each class are discussed.

• 한국표면공학회지
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• 제27권4호
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• pp.215-222
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• 1994

The role dispersoids has been studied in a number of researches as a key point for the high strength application of dispersion strengthened aluminum alloy. The mechanical alloying(MA) process with high mechanical properties of dispersion strengthened MA Al-8Ti-1B alloys were invested in order to evaluate their stress corrosion cracking(SCC) application. SCC properties of the mechanically alloyed Al-8Ti-1B were studied using slow strain rate test(SSRT). In this study Al-8Ti-1B alloy were more susceptible to SCC in solutions of pH=2.01 and 13.2 than pH=6.81 solution. In this study Al-8Ti-1B alloys by MA had more SCC resistance than Al-8Ti alloys or Al 7075-T73 alloys. So Al-8Ti-1B alloys by MA had more resistance in SSRT SCC susceptinility test than any other above alloying metals.

• Biomolecules & Therapeutics
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• 제32권2호
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• pp.231-239
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• 2024

Methyl anthranilate (MA) is a botanical fragrance used in food flavoring with unexplored potential in anti-pigment cosmetics. MA dose-dependently reduced melanin content without affecting cell viability, inhibited dendrite elongation and melanosome transfer in the co-culture system of human melanoma cells (MNT-1) and human keratinocyte cell line (HaCaT), and downregulated melanogenic genes, including tyrosinase, tyrosinase-related protein 1 and 2 (TRP-1, TRP-2). Additionally, MA decreased cyclic adenosine monophosphate (cAMP) production and exhibited a significant anti-pigmentary effect in Melanoderm^TM. These results suggest that MA is a promising anti-pigmentary agent for replacing or complementing existing anti-pigmentary cosmetics.

• Journal of applied mathematics & informatics
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• 제25권1_2호
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• pp.329-337
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• 2007

In the paper, we obtain the existence of positive solutions and establish a corresponding iterative scheme for BVPs $$\{^{\;(\phi_p(u'))'\;+\;q(t)f(t,u)=0,\;0\;<\;t\;<\;1,}_{\;u(0)\;-\;B(u'({\eta}))\;=\;0,\;u'(1)\;=\;0}$$ and $$\{^{\;(\phi_p(u'))'\;+\;q(t)f(t,u)=0,\;0\;<\;t\;<\;1,}_{\;u'(0)\;=\;0,\;u(1)+B(u'(\eta))\;=\;0.}$$. The main tool is the monotone iterative technique. Here, the coefficient q(t) may be singular at t = 0, 1.

• 디지털융복합연구
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• 제16권2호
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• pp.47-56
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• 2018

본 연구의 목적은 커플관계에 어려움을 경험하는 군 내 병사들의 커플관계 탄력성, 군 생활 스트레스, 군 생활 적응의 관계를 알아보는 것이다. 이를 위하여 전방 1개 사단, 후방 1개 사단에서 병사들을 대상으로 총 239부의 자료를 분석하였다. 자료 분석은 SPSS 18.0프로그램을 이용하여, 상관분석, t-test, 회귀분석을 실시하였고, 매개효과의 유의성을 검증하기 위하여 Sobel test를 실시하였다. 본 연구의 주요결과는 첫째, 커플관계탄력성은 군 생활 스트레스와는 부적 상관관계를 군생활 적응과는 정적상관관계를 나타내었다. 둘째, 커플관계 탄력성은 군 생활 적응에 유의미한 영향력을 나타내었다. 셋째, 군 생활 스트레스와 군 생활 적응의 관계에서 커플관계 탄력성은 부분 매개효과를 지니는 것으로 나타났다. 이러한 연구결과는 커플관계에 어려움을 호소하는 병사들의 군 생활 적응력을 높이기 위한 기초 자료로 사용될 수 있으며, 본 연구 결과를 활용하여 병사들의 군 생활 부적응 현상의 하나인 커플관계에 대한 이해를 높이고, 커플관계의 역경과 스트레스를 부정적으로 이해하는 것이 아니라 긍정적인 측면에서 성장 가능성을 찾도록 도와줄 수 있을 것으로 기대한다.

• 약학회지
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• 제59권3호
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• pp.92-97
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• 2015

KIOM-MA128 is a novel Korean herbal medicine with anti-atopic, anti-inflammatory and anti-asthmatic effects. This article presents the first pharmacokinetic study on KIOM-MA128. The purpose of this study was to characterize a pharmacokinetic characteristic of matrine, a potential marker of KIOM-MA128, in rats using population pharmacokinetic model. 1, 2 and 8 g/kg of KIOM-MA128 were administered to rats orally and plasma concentrations of matrine was determined by HPLC-MS/MS. Non-compartmental analysis (NCA) was performed using Phoenix$^{(R)}$ and pharmacokinetic model was built using NONMEM$^{(R)}$. This model was validated with internal validation which is visual predictive check (VPC) and bootstrap. The NCA result of matrine showed that $C_{max}$ was 294.24, 552.22 and 868.65 ng/ml, $AUC_{inf}$ was 1273.05, 2724.76 and $9743.25ng{\cdot}hr/ml$ and $T_{max}$ was 1, 1.3 and 2.3 hr for the doses of 1, 2, and 8 g/kg, respectively. The rat plasma concentrations were described very well with one-compartment model. Pharmacokinetic model for matrine was successfully developed and evaluated. Finally, our model is helpful to understand pharmacokinetic characteristic of KIOM-MA128.

• 접착 및 계면
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• 제11권3호
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• pp.106-111
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• 2010

PEGMA macromer를 Na-MMT에 삽입한 후 MMA 및 MA 단량체와의 공중합을 행하여 PEGMA/(Na-MMT)-co-MMA/MA 나노복합재료를 합성하고 이의 특성결정을 행하였다. 제조된 나노복합재료를 XRD로 관찰한 결과, Na-MMT에 PEGMA를 삽입하였을 경우 Na-MMT 양이 증가함에 따라 Na-MMT의 실리케이트 층간거리는 증가하였다. DSC 측정으로부터 Na-MMT 첨가량이 늘어날수록 Tg는 높아지는 경향을 보였다. TGA 측정을 통하여 PEGMA/(Na-MMT)-co-MMA/MA 나노복합재료는 순수한 PEGMA-co-MMA/MA보다 열안정성이 다소 향상됨을 확인하였다.

• 한국식품저장유통학회지
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• 제5권2호
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• pp.105-110
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• 1998

To find out suitable storage and marketing condition, northern type 'seosan' garlic was stored for 3 months at controlled atmosphere(CA), modified atmosphere(MA), low(0~1$^{\circ}C$) and room temperature(20$\pm$5$^{\circ}C$), and then marketed at low(2~3$^{\circ}C$) and room temperature (20$\pm$5$^{\circ}C$)after storage. The physiological properties of garlic were investigated among treatments. The garlic respiration increased after 2 months at room temperature storage, which seem to be dormancy break time. During storage of garlic by CA, MA condition, sprouting and weight loss were prevented effectively by suppress of respiration, and hardness was maintained higher then those of the others. Decay rate occurred 8.1% at room temperature storage, 2% at MA storage but didn't occurred at CA and low temperature storages. When marketed at room and low temperature after storage, increment of respiration and sprouting were delayed, and changes of weight and hardness were low in garlics stored at CA and MA. Decay rate occurred high in garlics stored at MA and room temperature.