• ETRI Journal
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• v.41 no.5
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• pp.658-669
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• 2019

For dual-channel time-frequency (TF) overlapped signals with low sparsity in underdetermined blind source separation (UBSS), this paper proposes an effective method based on interval probability to estimate and expand the types of mixing matrices. First, the detection of TF single-source points (TF-SSP) is used to improve the TF sparsity of each source. For more distinguishability, as the ratios of the coefficients from different columns of the mixing matrix are close, a local peak-detection mechanism based on interval probability (LPIP) is proposed. LPIP utilizes uniform subintervals to optimize and classify the TF coefficient ratios of the detected TF-SSP effectively in the case of a high level of TF overlap among sources and reduces the TF interference points and redundant signal features greatly to enhance the estimation accuracy. The simulation results show that under both noiseless and noisy cases, the proposed method performs better than the selected mainstream traditional methods, has good robustness, and has low algorithm complexity.

• ETRI Journal
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• v.37 no.2
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• pp.233-240
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• 2015

The novelty of this study resides in a 6"-wafer-level microfabrication protocol for a microdevice with a fluidic control system for the separation of circulating tumor cells (CTCs) from human whole blood cells. The microdevice utilizes a lateral magnetophoresis method based on immunomagnetic nanobeads with anti-epithelial cell adhesive molecule antibodies that selectively bind to epithelial cancer cells. The device consists of a top polydimethylsiloxane substrate for microfluidic control and a bottom substrate for lateral magnetophoretic force generation with embedded v-shaped soft magnetic microwires. The microdevice can isolate about 93% of the spiked cancer cells (MCF-7, a breast cancer cell line) at a flow rate of 40/100 mL/min with respect to a whole human blood/buffer solution. For all isolation, it takes only 10 min to process 400 mL of whole human blood. The fabrication method is sufficiently simple and easy, allowing the microdevice to be a mass-producible clinical tool for cancer diagnosis, prognosis, and personalized medicine.

• Korean Journal of Air-Conditioning and Refrigeration Engineering
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• v.10 no.6
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• pp.714-720
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• 1998

The differential pressure venturi-cone flowmeter is an advanced flowmeter which has many advantages such as wide range of measurement, high accuracy, excellent flow turn-down ratio, low headless, short installation pipe length requirement, and etc. Like other differential pressure flowmeters, the venturi-cone flowmeter uses the law of energy conservation, but its shape and position make it perform better than others. The cone acts as its own flow conditioner and mixer, fully conditioning and mixing the flow prior to measurement. For the analysis, we used Reynolds-averaged Wavier-Stokes equations and k-$\omega$ turbulence model. The equations were fully transformed into the computational domain, the pressure-velocity coupling was made through SIMPLER algorithm, and the equations were discretized using finite analytic solutions of the liberalized equations(Finite Analytic Method). To control the separation phenomenon on the cone surface, we proposed a new shape of cone, and analyzed the flowfield in the new flowmeter system, and found the improvement on the performance of the new cone flowmeter.

• Molecular & Cellular Toxicology
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• v.1 no.2
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• pp.87-91
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• 2005

Although 2D-PAGE has been widely used as the primary method for protein separation, difficulties in displaying proteins with an extreme values of isoelectric paint (pI), molecular size and hydrophobicity limit the technique. In addition, time consuming steps involving protein transfer and extraction from the gel-pieces can result in sample loss. Here, we describe a novel protein separation technique with capillary size-exclusion chromatography (CSEC) for rapid protein identification from human plasma. The method includes protein fractionation along with molecular size followed by in-solution tryptic digestion and peptide analysis through reversed phase liquid chromatography (RPLC) coupled to nanoflow electrospray-tandem mass spectrometry (ESI-MS/MS). Tryptic peptides are applied an a $100\;{\mu}m\;i.d.{\times}10mm$ length pre-column and then separated on a $75\;{\mu}m{\times}200mm$ analytical column at -100 nL/min flaw rate. Proteins were identified over the wide ranges of pI (3.7-12.3) when this technique was applied to the analysis of $1-2\;{\mu}L$ of human plasma. This gel-free system provides fast fractionation and may be considered a complementary technique to SDS-PAGE in proteomics.

• Journal of The Korean Astronomical Society
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• v.31 no.1
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• pp.27-37
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• 1998

We have made semi-analytical studies to investigate the configurations of caustics and the probability distribution of the flux factor K for the binary microlensing including external shears. A parametric equation of critical curve is derived in a 4th order complex polynomial. We present the topological dependencies of the caustics for selected gamma parameters (0, 0.3, 0.6, 1.3, 2.0, and 2.5) and convergence terms (0., 0.4, 0.8, 1.2, 1.6, and 2.0). For the purpose of analyzing the efficiency of High Amplification Event (HAE) on each caustics, we examine the probability distribution of the flux factor by a Monte Carlo method. Changing the separation of the binary system from 0.8 to 1.3 (in normalied unit), we examine the probability distribution of the K-values in various gamma parameters. The relationship between gamma parameters, seperations and their probabilties of the flux factor K have been studied. Our results show that the relatively higher K values (K>1.5) are increased as increasing the separation of the binary system. We therfore conclude that, in the N-body microlensing, the probabilities of higher HAEs are inversely proportional to the star density as well. We also point out that the present research might be used as a preliminary step toward investigating heavy N-body microlensing simulations.

• Journal of Pharmaceutical Investigation
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• v.22 no.1
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• pp.33-40
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• 1992

This study was aimed to control the release characteristics of ketoprofen by microencapsulating $ketoprofen-{\beta}-cyclodextrin\;(KF-{\beta}-CyD)$ solid dispersion with Eudragit RS by the phase separation method using a nonaqueous vehicle. KF alone was also microencapsulated with Eudragit RS by the evaporation process in water phase. The results obtained showed that it was not possible to microencapsulate KF alone by phase separation in a chloroform-cyclohexane system while it was easy to microencapsulate $(KF-{\beta}-CyD)$ solid dispersion system. For the microcapsules, the release test was performed in the first fluid (pH 1.2) and the second fluid (pH 6.8) of K.P.V disintegration medium at $37^{\circ}C$. The release of KF from $(KF-{\beta}-CyD)$ solid dispersion microcapsules (1:1 core wall ratio) was more sustained than that from KF microcapsules, and followed zero-order kinetics. Especially, solid dispersion microcapsules showed pH-independent release patterns with higher wall to core ratio (1:1 w/w).

• Journal of Ocean Engineering and Technology
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• v.22 no.3
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• pp.24-33
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• 2008

In this study, flow and creation and dissipation of vorticity around rectangular floating breakwater is investigated both experimentally and numerically. The PIV system(Particle image velocimetry) is employed to obtain the velocity field in the vorticity of rectangular structure. The numerical model, combined with ${\kappa}-{\varepsilon}$ turbulence model and the VOF method based on RANS equation, is used to analyze the turbulence structure. In the results of this study, the vorticity is found around conner of rectangular structure at all time domain, and creation and dissipation of vorticity are closely related to wave period. Separation points of phase of vortex due to flow separation for longer period waves are faster then for shorter period waves.

• Journal of the Korea Concrete Institute
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• v.17 no.1 s.85
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• pp.69-76
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• 2005

In this study, the high qualify recycled fine aggregate manufacturing system by the drying specific gravity separation method was evaluated. For the evaluation of the performance of the recycled aggregate, the engineering properties and durability of recycled aggregate has been tested. From the test results, the quality of recycled fing aggregates was improved by high quality recycled fine aggregate manufacturing system and satisfied with the quality standards of KS and JASS 5. Also, compressive and tensile strengths of recycled concrete show no critical difference caused by recycled fine aggregate replacement ratio. However, durability such as carbonation depth chloride ion penetration depth and drying shrinkage shows more deterioration than the concrete without recycled fine aggregate

• Resources Recycling
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• v.17 no.6
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• pp.43-49
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• 2008

In this study, a scrap sorting system using a color recognition method has been developed to automatically sort out specified materials from a mixture, and its application as been examined in the separation of Cu and other non-ferrous metal parts from a mixture of iron scraps. The system is composed of three parts; measuring, conveying and ejecting parts. The color of scrap surface is recognized by the measuring part consisting of a line-scan camera, light sources and a frame grabber. The recognition is program-controlled by a image processing algorithms, and thus only the scrap part of designated color is separated by the use of air nozzles. In addition, the light system is designed to meet a high speed of sorting process with a frequency-variable inverter and the air nozzled ejectors are to be operated by an I/O interface communication with a hardware controller. In the functional tests of the system, its efficiency in the recognition of Cu scraps from its mixture with Fe ones reaches to more than 90%, and that in the separation more than 80% at a conveying speed of 25 m/min. Therefore, it is expected that the system can be commercialized in the industry of shredder makers if a high efficiency ejecting system is realized.

• Journal of Satellite, Information and Communications
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• v.9 no.1
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• pp.74-78
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• 2014

In this paper, we proposed Interference suppression method of between AMI system and EV charging system. IEC12139-1 and HomePlug GreenPhy are using 2-30Mhz frequency band in power line communication. Both method while using the same frequency band, interference occurs in the system of each other. In this paper, we experiment a way to suppress the interference through the channel separation using a Walsh code.