• 한국전산유체공학회지
• /
• 제20권1호
• /
• pp.77-83
• /
• 2015

Flow characteristics of synthetic jet based flow supplying devices have been computationally investigated for different device shapes. Jet momentum was produced by the volume change of a cavity by two piezoelectric-driven diaphragms. The devices have additional flow path compared with the original synthetic jet actuator, and these flow path changes the flow characteristics of synthetic jet actuator. Four non-dimensional parameters, which were functions of the shapes of the additional flow path, were considered as the most critical parameters in jet performance. Comparative studies were conducted to compare volume flow rate and jet velocity. Computed results were solved by 2-D incompressible Navier-Stokes solver with k-w SST turbulence model. Detailed computations revealed that the additional flow path diminishes suction strength of the synthetic jet actuator. In addition, the cross section area of the flow path has more influence over the jet performances than the length of the flow path. Based on the computational results, the synthetic jet based flow supplying devices could be improved by applying suitable shape of the flow path.

• 대한의생명과학회지
• /
• 제7권3호
• /
• pp.103-110
• /
• 2001

$\alpha$-Fetoprotein(AFP) is a good marker for the detection of several diseases such as hepatocellular carcinoma, gonadal germ cell tumor, gastric tumor, and Down's syndrome. In this study, we developed ELISA, using synthetic peptides corresponding to the epitopes of AFP. Five kinds of peptides were synthesized from AFP to produce antibodies in rats that recognize AFP in human plasma as well as amniotic fluid and do not cross-react with serum albumin. All five kinds of antibodies showed good reactivities with their peptide-keyhole limpet hemocyanin conjugates. Anti-synthetic peptide 1 (R-N-E-Y-G-I-A-S-I-L, 4-13) antibody, in particular, reacted well with AEP as well as synthetic peptide 1-KLH but not with human serum albumin. The binding affinity(Kd) was 2.7$\times$10$^{-9}$M for peptide 1 and 6.8$\times$10$^{-8}$M for AEP. The range for measurement of AFP was 10~1,000 ng/ml. The within-assay and between-assay coefficients of variance(CV) were 4.83% and 10.97%, respectively. In a sample of 31 sera and 33 amniotic fluids, there was a good correlation between AFP values determined in this assay and those in a commercial kit. These results indicate that the antibodies against synthetic peptides corresponding to the epitopes of AFP are highly specific to APP and synthetic peptide-based ELISA would be useful for the measurement of human AFP.

• 대한조선학회논문집
• /
• 제44권4호
• /
• pp.389-397
• /
• 2007

This research describes a framework to compare and analyze the icebreaker(Terry Fox) resistance in pack ice condition between with a refrigerated ice and a synthetic ice. Model tests with a refrigerated ice have been conducted at Institute for Ocean Technology (IOT/NRC) and the tests with a synthetic ice were conducted at Pusan National University towing tank. For the validation of further tests of measurement and accuracy, the open water tests were first carried out with same model ship to compare the test results of both Institutes. Two different size of the wax-type synthetic ice were used and tests were conducted in pack ice of three different concentration ice conditions. The test results show that the difference of resistance between with synthetic and with refrigerated ice becomes larger according to the increase of ship speed. Although the quantity of resistance difference is not so small in high speed range, the present study is predicted to be used as a useful correlation between synthetic and refrigerated ice.

• 전자공학회논문지S
• /
• 제35S권7호
• /
• pp.95-102
• /
• 1998

This paper proposes a synchronization method of synthetic facial iamge sequences and synthetic speech. The LP-PSOLA synthesizes the speech for each demi-syllable. We provide the 3,040 demi-syllables for unlimited synthesis of the Korean speech. For synthesis of the Facial image sequences, the paper defines the total 11 fundermental patterns for the lip shapes of the Korean consonants and vowels. The fundermental lip shapes allow us to pronounce all Korean sentences. Image synthesis method assigns the fundermental lip shapes to the key frames according to the initial, the middle and the final sound of each syllable in korean input text. The method interpolates the naturally changing lip shapes in inbetween frames. The number of the inbetween frames is estimated from the duration time of each syllable of the synthetic speech. The estimation accomplishes synchronization of the facial image sequences and speech. In speech synthesis, disk memory is required to store 3,040 demi-syllable. In synthesis of the facial image sequences, however, the disk memory is required to store only one image, because all frames are synthesized from the neutral face. Above method realizes synchronization of system which can real the Korean sentences with the synthetic speech and the synthetic facial iage sequences.

• Carbon letters
• /
• 제5권3호
• /
• pp.133-141
• /
• 2004

The synthetic behaviors of carbon nanotubes (CNTs) by Fe/MgO catalysts were investigated in 0~90 wt.% range of MgO mixture ratios by catalytic chemical vapor deposition (CCVD) process. The CNTs were synthesized with 40 minutes of synthetic time, and 923 K of synthetic temperature using 0.1 L/min of ethylene gas and 1.0 L/min of hydrogen gas as synthetic and carrier gas, respectively. As the increase of synthetic temperatures and times, the diameters of CNTs become thicker. The carbon yield showed in a parabolic curve as MgO content increased and the maximum carbon yield was obtained at 30 wt.% of MgO. There were no obvious changes in the diameters of CNTs respect to the change of MgO content. Fe/MgO CNTs showed good crystalinity by High Resolution Transmission Electron microscope (HR-TEM) analysis. The behaviors of Fe/MgO CNTs have a tendency of depending on synthetic time and temperature rather than MgO content.

• Clinical and Experimental Pediatrics
• /
• 제62권5호
• /
• pp.155-161
• /
• 2019

Following the first successful trial of surfactant replacement therapy for preterm infants with respiratory distress syndrome (RDS) by Fujiwara in 1980, several animal-derived natural surfactants and synthetic surfactants have been developed. Synthetic surfactants were designed to overcome limitations of natural surfactants such as cost, immune reactions, and infections elicited by animal proteins contained in natural surfactants. However, first-generation synthetic surfactants that are protein-free have failed to prove their superiority over natural surfactants because they lack surfactant protein (SP). Lucinactant, a second-generation synthetic surfactant containing the SP-B analog, was better or at least as effective as the natural surfactant, suggesting that lucinactant could act an alternative to natural surfactants. Lucinactant was approved by the U. S. Food and Drug Administration in March 2012 as the fifth surfactant to treat neonatal RDS. CHF5633, a second-generation synthetic surfactant containing SP-B and SP-C analogs, was effective and safe in a human multicenter cohort study for preterm infants. Many comparative studies of natural surfactants used worldwide have reported different efficacies for different preparations. However, these differences are believed to due to site variations, not actual differences. The more important thing than the composition of the surfactant in improving outcome is the timing and mode of administration of the surfactant. Novel synthetic surfactants containing synthetic phospholipid incorporated with SP-B and SP-C analogs will potentially represent alternatives to natural surfactants in the future, while improvement of treatment modalities with less-invasive or noninvasive methods of surfactant administration will be the most important task to be resolved.

• 한국분무공학회지
• /
• 제28권3호
• /
• pp.143-149
• /
• 2023

Amidst the drive towards carbon neutrality, interest in renewable synthetic e-fuels is rising rapidly. These fuels, generated through the synthesis of atmospheric carbon and green hydrogen, offer a sustainable solution, showing advantages like high energy density and compatibility with existing infrastructure. The physical properties of e-fuels can be different from those of conventional gasoline based on manufacturing methods, which requires investigations into how the physical properties of e-fuels affect the fuel injection characteristics. This study performs a comparative analysis between conventional and Fischer-Tropsch (F-T) synthetic gasoline (e-gasoline) across various fuel temperatures, including the cold start condition. The fuel properties of F-T synthetic and conventional gasoline are analyzed using a gas chromatography-mass spectrometry technique and the injection rates are measured using a Bosch-tube injection rate meter. The F-T synthetic gasoline exhibited higher density and kinematic viscosity, but lower vapor pressure compared to the conventional gasoline. Both fuels showed an increase in injection rate as the fuel temperature decreased. The F-T synthetic gasoline showed higher injection rates compared to conventional gasoline regardless of the fuel temperature.

• 응용통계연구
• /
• 제36권4호
• /
• pp.279-294
• /
• 2023

재현자료를 생성할 때 순차회귀 다중대체(SRMI)를 이용하는 방식이 가장 널리 알려져 있으며, 이를 구현한 소프트웨어로 R-패키지 synthpop이 활용되고 있다. 본 논문에서는 확률적 주성분 분석(PPCA)을 이용하여 재현자료를 생성하는 방안을 제안하고 2개의 데이터 세트를 이용한 모의실험으로 SRMI 방식과 PPCA 방식을 비교하였다. 모의실험에서 PPCA 방식으로 생성한 재현자료는 쌍별 상관계수를 기준으로 원자료와의 유사성이 가장 우수함을 확인하였다. 향후 PPCA 방식을 이용하여 시계열 자료에 대한 재현자료 생성을 연구하고자 한다.

• Journal of Microbiology and Biotechnology
• /
• 제33권4호
• /
• pp.552-558
• /
• 2023

Levulinic acid (LA) is a valuable chemical used in fuel additives, fragrances, and polymers. In this study, we proposed possible biosynthetic pathways for LA production from lignin and poly(ethylene terephthalate). We also created a genetically encoded biosensor responsive to LA, which can be used for screening and evolving the LA biosynthesis pathway genes, by employing an LvaR transcriptional regulator of Pseudomonas putida KT2440 to express a fluorescent reporter gene. The LvaR regulator senses LA as a cognate ligand. The LA biosensor was first examined in an Escherichia coli strain and was found to be non-functional. When the host of the LA biosensor was switched from E. coli to P. putida KT2440, the LA biosensor showed a linear correlation between fluorescence intensity and LA concentration in the range of 0.156-10 mM LA. In addition, we determined that 0.156 mM LA was the limit of LA detection in P. putida KT2440 harboring an LA-responsive biosensor. The maximal fluorescence increase was 12.3-fold in the presence of 10 mM LA compared to that in the absence of LA. The individual cell responses to LA concentrations reflected the population-averaged responses, which enabled high-throughput screening of enzymes and metabolic pathways involved in LA biosynthesis and sustainable production of LA in engineered microbes.

• 한국의류학회지
• /
• 제21권6호
• /
• pp.970-976
• /
• 1997

Synthetic leather added collagen protein was coagulated in DMF solution. With increasing collagen concentration, thickness of synthetic leather increased. In addition, water vapor permeability and water vapor absoption increased with increasing collagen protein concentration. But MIU and SMD value of surface properties decreased with increasing collagen protein concentration. As a result, synthetic leather added collagen protein showed comfort and dry touch.