• Title/Summary/Keyword: symptom

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STUDY ON ANALYSIS OF SIGNIFICANCE OF SYMPTOM-TREATMENT METHOD COMBINATION

  • Oh, Yong Taek;Nam, Bo Ryeong;Kim, An Na
    • Journal of applied mathematics & informatics
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    • v.32 no.5_6
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    • pp.737-746
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    • 2014
  • Treatment method refers to a principle or method for treating diseases in Traditional Korean Medicine(TKM). As doctors determine the ideal treatment for a patient's disease or symptom, they are also able to prescribe effective treatment means for the diseases or symptom such as medicinal materials, prescription, acupuncture and moxibustion. Therefore, if significant symptom-treatment method combinations are found from literature or database, proper treatment means for the patient's diseases or symptom may be presented to TKM doctors and enhanced treatment accuracy and efficiency can be expected. This study aims to analyze the relation between symptom and treatment method by interpreting hypotheses through null hypotheses to find significant symptom-treatment method combinations. This combinations suggested in this study will be compared with TKM experts analysis result to find an objective analysis method and eventually apply the method to medical big data, e.g., a huge amount of literature or treatment records.

A Study on the Differentiation of Women with Perimenstrual Symptom Severity and Perimenstrual Distress Patterns (월경 전후기 증상 정도 및 월경고통 유형 판별요인)

  • Park, Young-Joo;Ryu, Ho-Shin
    • Women's Health Nursing
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    • v.4 no.1
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    • pp.123-138
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    • 1998
  • The purpose of this study was to describe perimenstrual symptom severity levels and perimenstrual distress patterns of women. The study performed the discriminant analysis in which included seven factors : age, pariety, social support, menstrual socialization(mother's symptom, sister's symptom, and menstrual effect), attitude of sex role and depression. The subjects were 283 women that they were not pregnant or lactating, had at least one period in past three months, would understand the purpose of study and willingly accepted the participation. The data analysis was done by pc-SAS program after data collection from Nov. 20, 1997 to Dec. 18, 1997. The descriptive analysis was done to explore general characteristics of the subjects and the stepwise discriminant analysis was done to verify factors in relation to perimenstrual symptom severity levels(severe vs mild menstrual symptom group) and perimenstrual distress patterns(spasmodic vs congestive menstrual symptom group). The instruments were selected for this study from Interpersonal Support Evaluation List(ISEL) by Cohen and Hoberman(1983), Center for Epidemic Studies Depression(CES-D) by Radloff(1977), and Sex Role Attitude Scale by Yunok Suh(1995), Mother's symptom and sister's symptom measurements by Woods, Mitchell & Lentz(1995), and menstrual effect by Brooks-Gun & Ruble(1980). The major findings of this study are as follows : 1. Of the 283 women, 93 women(32.9%) were assessed to severe perimenstrual symptom group and 190 women(67.1%) were assessed to mild perimenstrual symptom group. Results from the stepwise discriminant analysis showed three factors, such as depression, menstrual effect, and age, significantly related to perimenstrual symptom severity and they explained 20% of the total variance. The linear discriminant equation included three factors related to perimenstrual symptom groups was showed(Z=1.445 depression+0.174 menstrual effect-0.054 age). The cutting score(Z) was 2.809. We classified the severe perimenstrual symptom group by more than the cutting score 2.809 and the mild perimenstrual symptom by less or equal than the cutting score 2.809. The correctedness of posterior probability from discriminant equation was 72% as two perimenstrual symptom group classifications. 2. Of the 264 women, 139 women(52.7%) were assessed to spasmodic perimenstrual distress group and women(47.3%) were assessed to congestive perimenstrual distress group. Results from the stepwise discriminant analysis showed two factors, such as depression, age, significantly related to perimenstrual distress groups and they explained 8% of the total variance. The linear discriminant equation included two factors related to perimenstrual distress group was showed(Z=-0.084 age-0.776 depression). The cutting score(Z) was -3.759. We classified the spasmodic perimenstrual distress group by more than cutting score -3.759 and the congestive perimenstrual distress group by less or equal than cutting score -3.759. The correctedness of posterior probability from discriminant equation was 65% as two perimenstrual distress group classifications.

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Symptom Management to Predict Quality of Life in Patients with Heart Failure: A Structural Equation Modeling Approach (증상관리를 통한 심부전 환자의 삶의 질 예측모형)

  • Lee, Ja Ok;Song, Rhayun
    • Journal of Korean Academy of Nursing
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    • v.45 no.6
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    • pp.846-856
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    • 2015
  • Purpose: The focus of this study was on symptom management to predict quality of life among individuals with heart failure. The theoretical model was constructed based on situation-specific theory of heart failure self-care and literature review. Methods: For participants, 241 outpatients at a university hospital were invited to the study from May 19 to July 30, 2014. Data were collected with structured questionnaires and analyzed using SPSSWIN and AMOS 20.0. Results: The goodness of fit index for the hypothetical model was .93, incremental fit index, .90, and comparative fit index, .90. As the outcomes satisfied the recommended level, the hypothetical model appeared to fit the data. Seven of the eight hypotheses selected for the hypothetical model were statistically significant. The predictors of symptom management, symptom management confidence and social support together explained 32% of the variance in quality of life. The 28% of variance in symptom management was explained by symptom recognition, heart failure knowledge and symptom management confidence. The 4% of variance in symptom management confidence was explained by social support. Conclusion: The hypothetical model of this study was confirmed to be adequate in explaining and predicting quality of life among patients with heart failure through symptom management. Effective strategies to improve quality of life among patients with heart failure should focus on symptom management. Symptom management can be enhanced by providing educational programs, encouraging social support and confidence, consequently improving quality of life among this population.

A Study on Relationship of Symptom Distress and Natural Killer Cell Cytotoxicity in Breast Cancer Patients (치료 중인 유방암 환자의 신체적 증상과 자연살해세포 활성도의 관계)

  • Chae, Young-Ran
    • Journal of Korean Biological Nursing Science
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    • v.4 no.2
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    • pp.69-77
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    • 2002
  • The purpose of this study was to identify the relationship of symptom distress and natural killer cell cytotoxicity in breast cancer patients who had been radiation therapy and/or chemotherapy after surgery. Symptom distress measured by modified Lee's(1994) physical symptom questionnaire. For measuring the natural killer cell cytotoxic activity. 8ml to 10ml blood was collected from the subjects. Mononuclear cell was isolated by centrifuge of the blood and cultured by putting $Cr^{51}$, and reacted with target cell, K562 cell. Amount of $Cr^{51}$ was measured, and %lysis was calculated. The results were as follows. 1) Symptom distress score was 42.18, which is moderate symptom distress. 2) Natural killer cell cytotoxic activities were 42.18%lysis(effector : target cell ratio=100 : 1) and 28.05%lysis(effector : target cell ratio=50 : 1). 3) Correlation coefficients of symptom distress and natural killer cell cytotoxic activity were $-.134{\sim}-.461$. Though significant correlation was not found between total score of symptom distress and natural killer cell cytotoxic activity, 3('pain' 'feel hot on radiation site' and 'difficulty in breathing') of 19 symptom distress items and natural killer cell cytotoxic activity showed significant negative correlation(p<.05). These findings suggest that 1) breast cancer patients who had been radiation therapy and/or chemotherapy after surgery have moderate symptom distress and decreased natural killer cell cytotoxic activity. 2) The symptom distress was not related to natural killer cell cytotoxic activity.

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A Study on the Development of Diagnostic Index for the Ordinary Symptom of Soyangin (소양인 소증 진단평가지표 개발 연구)

  • Cho, Young;Lee, Jun-Hee
    • Journal of Sasang Constitutional Medicine
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    • v.32 no.4
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    • pp.45-64
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    • 2020
  • Purpose This study was to develop and study 'Diagnostic Index for the Ordinary Symptom of Soyangin'. Methods The main diagnosis and evaluation index symptoms of Soyangin were extracted based on 『Donguisusebowon』 and Clinical Practice Guidelines for Sasang Constitutional Medicine Symptomatology; CPG for soyangin. The selected ordinary symptoms were divided into 4 categories such as Exterior-Cold ordinary symptom (表寒素證), Exterior-Disease unfavorable's ordinary symptom (表病逆證素證), Interior-Heat ordinary symptom (裏熱素證), Interior-Disease unfavorable's ordinary symptom (裏病逆證素證) of Soyangin and translated into Korean. And the inclusion, importance and translation validity of major diagnosis and assessment indicators of Soyangin were surveyed online by a group of Sasang constitutional experts. Results & Conclusions 29 ordinary symptoms and pathological mechanism were selected from references and translated into 51 Korean symptoms. After inclusion yes or no survey by expert group, 45 symptoms were selected. The importance survey showed that 'Have a soft stool' of Exterior-Cold ordinary symptom indication, '(If you're stressed, if you're not in good health) Have a soft stool or diarrhea' of Exterior-Disease unfavorable's ordinary symptom, 'The feces harden easily' of Interior-Heat ordinary symptom and '(If you're stressed, if you're not in good health) Have an upset stomach' of Interior-Disease unfavorable's ordinary symptom were the most important. Finally, [Diagnostic Index for the Ordinary Symptom of Soyangin] was completed after survey of translation validity, reflection of individual opinions by the expert committee, and application of weighted value calculated from the importance survey.

A Study on the Relationship between Climacteric Symptom, Depression and Coping among Middle-Aged Women (중년여성의 갱년기 증상, 우울과 대처와의 관계)

  • Choi, Kwang-Sim;Oh, Hyun-Ei;Shim, Chung-Sin
    • Journal of agricultural medicine and community health
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    • v.33 no.3
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    • pp.335-345
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    • 2008
  • = ABSTRACT = Objectives: The purpose of this study were to examine the level of climacteric symptom, coping and depression among middle-aged women and to identify the relationship between climacteric symptom, coping and depression. Methods: A descriptive correlational study was conducted. The participants were 275 middle-aged women visiting obstetrics and gynecology hospital in one metropolitan city. Data were collected using a self-administered questionnaire. Descriptive statistics, ANOVA and Pearson correlation were used for data analysis. Results: The mean climacteric symptom score was .54, the mean depression score was .74 and the mean coping score was .35. The level of climacteric symptom, depression and coping were slightly lower than those of other studies. There were positive relationships between climacteric symptom and depression and between climacteric symptom and coping. Conclusions: To promote physical and emotional health of middle-aged women, more attention is necessary to decrease their climacteric symptom and depression. These results can be used for nursing intervention and care programs for creating better quality of life for middle-aged women.

A Study on the Concept of 'Physical symptom(形證)' in Dong-uibogam - Focused on Physical symptom & Medication of Six Meridians in the Han(寒) Chapter - (『동의보감(東醫寶鑑)』의 '형증(形證)' 개념(槪念)에 대한 고찰 - ≪한(寒)≫ <육경형증용약(六經形證用藥)>을 중심으로 -)

  • Shin, Sang-Won;Jeong, Chang-Hyun;Baik, You-Sang;Jang, Woo-Chang
    • Journal of Korean Medical classics
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    • v.27 no.4
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    • pp.101-119
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    • 2014
  • Objectives : In Dong-uibogam, Heo Jun used the concept of 'Physical symptom(形證)' that had not used frequently in practical description of pathological condition. Especially, He used the terminology, 'Physical symptom(形證)' as a title in the Han(寒) Chapter that described Sanghan(傷寒). Methods : It has been done to analyse verses that include the concept of 'Physical symptom(形證)' in Dong-uibogam. And, to find the context including the terminology diachronically. Results : Diachronically, 'physical symptom' and 'pulse sign' had been considered as bilateral factors of disease, and Heo jun cognized the concept of 'Physical symptom' in these means in Dong-uibogam. Conclusions : Introducing the concept of 'Physical symptom' is an important decision of Heo Jun, it can express the purpose of an observation to objective symptoms.

Factors influencing Symptom Experience in Patients with Liver Cirrhosis (간경변 환자의 증상경험에 영향을 미치는 요인)

  • Kim, Soo Hyun
    • Korean Journal of Adult Nursing
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    • v.17 no.2
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    • pp.248-258
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    • 2005
  • Purpose: The purpose of this study is to examine the factors influencing symptom experience in patients with liver cirrhosis(LC). Method: A descriptive correlational study design was used. A convenience sample of 129 subjects was recruited from the gastroenterology department at two university hospitals in Seoul, Korea. Symptom experience in LC was measured with the instrument developed by the researcher based on Theory of Unpleasant Symptoms(Lenz et al, 1995) and the Child-Pugh Score, the Korean version of Profile of Mood States, and the Family Support Questionnaire were used to identify the factors influencing symptom experience. Results: The mean score of symptom experience was relatively low(M=41.67, SD= 24.71). Among individual symptoms, fatigue had the highest score in all dimensions. Fatigue, abdominal distension and/or peripheral edema, muscle cramps, dry mouth, and change in appearance were explored as symptoms needing management. In the regression analysis, symptom experience was found to be influenced significantly by anxiety/depression($R^2=.418$, p=.000) and the severity of LC(Child-Pugh Score)($R^2=.125$, p=.000). These variables explained 54.3% of the variance in symptom experience(F=63.607. p=.000). Conclusion: It suggests that nurses need to take into consideration psychological factor as well as physiological factor in symptom management for patients with LC.

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The Mediating Effects of Nutritional Status on the Relationship between Symptom Experience and Functional Status in Patients with Chronic Obstructive Pulmonary Disease (만성 폐쇄성 폐질환 환자의 증상경험과 기능상태의 관계에 미치는 영양상태의 매개효과)

  • Jang, Jun Hee;Min, Hye Sook
    • Journal of muscle and joint health
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    • v.25 no.2
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    • pp.112-121
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    • 2018
  • Purpose: This study was conducted to explore the mediating effect of nutritional status on the relationship between symptom experience and functional status of patients with Chronic Obstructive Pulmonary Disease (COPD). Methods: A total of 141 COPD patients visiting D hospital and I hospital in B city were enrolled in this study. Data were collected from January 2017 to July 2017. Outcome variables were measured by Mini Nutritional Assessment Short-Form (MNA-SF) for nutritional status, The Memorial Symptom Assessment Scale (MSAS) for symptom experience, and The Functional Performance Inventory Short Form (FPI-SF) for functional status. The data were analyzed with descriptive statistics, Pearson's correlation, and path analysis using SPSS/WIN 21.0 and AMOS 25. Results: There was a significant negative correlation between symptom experience and nutritional status (r=-.61, p<.001), a significant negative correlation between symptom experience and functional status (r=-.40, p<.001), and significant positive correlation between nutritional status and functional status (r=.47, p<.001). Symptom experience had indirect effects on functional status through nutritional status. Conclusion: For enhancing functional status in COPD patients, it is necessary to develop nursing intervention programs to enhance symptom management as well as nutritional status.

Symptom Clusters and Quality of Life in Patients on Hemodialysis (혈액투석 환자의 증상 클러스터와 삶의 질)

  • Cha, Jieun;Yi, Myungsun
    • Journal of Korean Clinical Nursing Research
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    • v.20 no.1
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    • pp.123-133
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    • 2014
  • Purpose: The purpose of the study was to investigate symptom clusters experienced by patients on hemodialysis and to identify relations between symptom clusters and quality of life. Methods: Data were collected from 127 patients at 10 local hemodialysis clinics. Symptoms were measured using 10-item physical symptom checklist as well as the Hospital Anxiety depression Scale. Quality of life was measured with the Satisfaction with Life Scale. Data were analyzed using factor analysis, Pearson correlation, and stepwise multiple regression. Results: The most frequently reported symptoms included fatigue, itching, depression, numbness/tingling, and insomnia. Four distinct symptom clusters were identified: cluster 1 was comprised of dry mouth, headache, nausea (gastrointestinal); cluster 2 of decreased appetite, insomnia (basic need); cluster 3 of itching, numbness/tingling (sensory-comfort); and cluster 4 of fatigue, depression (mood-vitality). Among the clusters, the 'basic need' cluster and 'mood-vitality' cluster had a significant negative association with quality of life. The 'mood-vitality' cluster, explained 17.4% of the variance in quality of life. Conclusion: The results of the study indicate that comprehensive symptom assessment provides better symptom management for patients on hemodialysis. Further studies are needed to verify symptom clusters identified in this study.