• 제목/요약/키워드: survival regression

검색결과 620건 처리시간 0.026초

Shift in benthic diatom community structure and salinity thresholds in a hypersaline environment of solar saltern, Korea

  • Bae, Hanna;Park, Jinsoon;Ahn, Hyojin;Khim, Jong Seong
    • ALGAE
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    • 제35권4호
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    • pp.361-373
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    • 2020
  • The community dynamics of benthic diatoms in the hypersaline environment are investigated to advance our understanding how salinity impacts marine life. Diatoms were sampled in the two salterns encompassing salt Ponds, ditches, and seawater reservoirs (n = 11), along the salinity gradient (max = 324 psu), and nearby tidal flats (n = 2). The floral assemblages and distributions across sites and stations showed great variations, with a total of 169 identified taxa. First, not surprisingly, higher diversity of benthic diatoms was found at natural tidal flats than salterns. The saltern diatoms generally showed salinity dependent distributions with distinct spatial changes in species composition and dominant taxa. Biota-environment and principal component analysis confirmed that salinity, mud content, and total nitrogen were key factors influencing the overall benthic community structure. Some dominant species, e.g., Nitzschia scalpelliformis and Achnanthes sp. 1, showed salinity tolerance / preference. The number of diatom species at salinity of >100 psu reduced over half and no diatoms were found at maximum salinity of 324 psu. The highest salinity for the observed live diatoms was 205 psu, however, a simple regression indicated a theoretical salinity threshold of ~300 psu on the survival. Finally, the indicator species were identified along the salinity gradient in salterns as well as natural tidal flats. Overall, high species numbers, varying taxa, and euryhaline distributions of saltern diatoms collectively reflected a dynamic saltern ecosystem. The present study would provide backgrounds for biodiversity monitoring of ecologically important microalgal producers in some unique hypersaline environment, and elsewhere.

ERP 시스템 도입유형이 기업의 IT·SW 활용에 미치는 영향에 관한 실증연구 (An Practical Study on the Effect of ERP System Introduction Type on the Enterprise's IT·SW Utilization)

  • 양희정;성욱준
    • 한국IT서비스학회지
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    • 제20권2호
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    • pp.57-76
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    • 2021
  • Today's ERP system has become a core system of IT·SW that not only supports and manages enterprise resources efficiently, but also encompasses major business tasks. In other words, the ERP system is an essential strategic element for the survival of a company as a powerful means to innovate the management of an organization. This study analyzed the impact on the utilization of IT·SW from the perspective of the entire organization's process without limiting the performance evaluation of the ERP system itself, which is a core system of a company. The measurement data for evaluating the performance of the ERP system was the 2018 domestic company IT·SW utilization survey result report (subject to survey : 3,017 domestic companies with 10 or more employees). Based on this data, this study analyzed the impact of the ERP system on the entire enterprise's IT·SW utilization. In particular, attention was paid to whether there would be a difference in the use of IT·SW if the type of ERP system introduction was changed through the improvement of the business process of the company. Multiple regression analysis was performed using the statistical package SPSS 25. As a result, among the ERP system introduction types, the greatest degree of (+)influence on the company's IT·SW utilization is when the ERP package SW or ASP service is used as it is. Although the difference is insignificant, the second case was to build an ERP system through self-development or outsourcing, followed by customizing the package SW or system through self-development or outsourcing. Through the results of this study, it is expected that the organization will improve the business process and use the standard ERP package SW as it is without modification, thereby effectively enhancing the use of IT·SW of the company and leading to management performance.

Long-term outcomes of adjacent and antagonistic teeth after implant restoration: a focus on patient-related factors

  • Park, Su-Yeon;Kim, Yong-Gun;Suh, Jo-Young;Lee, Du-Hyeong;Lee, Jae-Mok
    • Journal of Periodontal and Implant Science
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    • 제51권2호
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    • pp.135-143
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    • 2021
  • Purpose: To investigate factors affecting the antagonistic and adjacent teeth in patients after implant restoration and prosthetic rehabilitation. Methods: In total, 160 patients who visited Kyungpook National University Dental Hospital for implant surgery, prosthesis placement, and supportive periodontal therapy (SPT) were included in this study. The average follow-up period was 88.06 months, and the maximum was 175 months. Patients' history of smoking, diabetes, hypertension, and osteoporosis was investigated, and panoramic radiographs were taken after surgery and prosthetic treatment. During the follow-up period, extraction and prosthetic/endodontic treatments of the antagonistic and adjacent teeth were analyzed. The statistical analyses were performed using descriptive statistics, the chi-square test, the Fisher exact test, and multiple logistic regression analyses. Results: Treatment was performed on 29.4% of the studied antagonistic teeth with extraction performed in 20.0% and prosthetic treatment in 10.0%. Furthermore, 19.4% of the studied adjacent teeth underwent treatment, of which extraction was performed in 12.5% and prosthetic treatment in 7.5%. The treatment rate for adjacent teeth was 25.3% in smokers, which was higher than that of non-smokers (12.3%) (P=0.039). Patients who were non-adherent to SPT showed a significantly higher rate (19.6%) of antagonistic prosthetic treatment than did those who were adherent (5.5%) (P=0.006). Conclusions: Implant restoration can affect the adjacent and antagonistic teeth. Smoking, osteoporosis history, and absence of SPT may be risk factors for the treatment of the adjacent and antagonistic teeth.

Prognostic Role of Circulating Tumor Cells in the Pulmonary Vein, Peripheral Blood, and Bone Marrow in Resectable Non-Small Cell Lung Cancer

  • Lee, Jeong Moon;Jung, Woohyun;Yum, Sungwon;Lee, Jeong Hoon;Cho, Sukki
    • Journal of Chest Surgery
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    • 제55권3호
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    • pp.214-224
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    • 2022
  • Background: Studies of the prognostic role of circulating tumor cells (CTCs) in early-stage non-small cell lung cancer (NSCLC) are still limited. This study investigated the prognostic power of CTCs from the pulmonary vein (PV), peripheral blood (PB), and bone marrow (BM) for postoperative recurrence in patients who underwent curative resection for NSCLC. Methods: Forty patients who underwent curative resection for NSCLC were enrolled. Before resection, 10-mL samples were obtained of PB from the radial artery, blood from the PV of the lobe containing the tumor, and BM aspirates from the rib. A microfabricated filter was used for CTC enrichment, and immunofluorescence staining was used to identify CTCs. Results: The pathologic stage was stage I in 8 patients (20%), II in 15 (38%), III in 14 (35%), and IV in 3 (8%). The median number of PB-, PV-, and BM-CTCs was 4, 4, and 5, respectively. A time-dependent receiver operating characteristic curve analysis showed that PB-CTCs had excellent predictive value for recurrence-free survival (RFS), with the highest area under the curve at each time point (first, second, and third quartiles of RFS). In a multivariate Cox proportional hazard regression model, PB-CTCs were an independent risk factor for recurrence (hazard ratio, 10.580; 95% confidence interval, 1.637-68.388; p<0.013). Conclusion: The presence of ≥4 PB-CTCs was an independent poor prognostic factor for RFS, and PV-CTCs and PB-CTCs had a positive linear correlation in patients with recurrence.

원전 디지털 I&C 계통 고장예측을 위한 신뢰도 함수 추정 인공지능 모델 비교연구 (Comparative Study of AI Models for Reliability Function Estimation in NPP Digital I&C System Failure Prediction)

  • 이대영;이정훈;양승혁
    • 한국산업정보학회논문지
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    • 제28권6호
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    • pp.1-10
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    • 2023
  • 원전 계측제어계통은 정상운전 시 자가 진단기능의 유지보수를 위해 일정 주기로 건전성을 확인하고 있으며, 계획예방정비 기간 동안 기능 및 성능점검을 실시하여 필요한 경우 유지보수를 하고 있다. 하지만 원전의 정보를 계측하고 제어하는 계측제어계통에서도 선제적으로 고장을 진단하고 대처하여 사고전파를 방지할 수 있는 기술개발이 필요하다. 이에 본 논문에서는 계측제어 장비의 환경조건과 자가 진단 데이터를 활용한 신뢰도 함수 추정 방안을 연구하였으며, 고장데이터의 획득을 위해 계측제어 장비의 부품에 대한 Feature 별 확률분포를 가정하여 가상 고장데이터를 생산하였다. 이러한 고장데이터를 바탕으로 생존분석에서 활용되는 대표적인 인공지능 모델(DeepSurve, DeepHit)을 이용하여 신뢰도 함수를 추정하였고, 그와 동시에 전통적인 준모수적 방법론인 Cox 회귀모델을 통해 신뢰도 함수를 추정하여 환경조건과 진단 데이터를 바탕으로 한 잔여 수명 계산을 통해 적용 가능성을 확인하였다.

조직 내 정보시스템의 양면적 사용 (Ambidextrous Use of Information Systems in an Organization)

  • 강현정;김미희
    • 경영정보학연구
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    • 제22권1호
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    • pp.167-182
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    • 2020
  • 조직의 양면성은 일반적으로 경쟁적 시장에서 생존하기 위해 중요한 조직적 혁신을 가능하게 하는 유연성으로 해석된다. 정보시스템 사용자의 탐색적 혹은 활용적 사용의 양면성이 역동적 혹은 운영적 작업 간에 유연한 전환을 가능하게 하여 결과적으로 작업성과를 높이는 데 기여하게 된다. 본 연구는 개인 수준에서의 정보시스템 사용 양면성의 보완적 적합성이 업무 성과를 향상시키는지 검증하고자 하였다. 나아가 이 둘이 양면적 사용에서 차지하는 비중에 따라 업무의 유형에 따른 성과에 기여하는지도 알아보았다. 다항적 회귀분석과 표면분석을 통해 정보시스템 사용 패턴의 부조화적 적합성의 효과를 확인하였다. 이를 확산적 양면성과 수렴적 양면성으로 분류하고 각 패턴의 효과는 작업의 역동적 혹은 운영적 유형에 따라 다르게 나타남을 확인하였다.

팀 기반 심폐소생술 시뮬레이션 교육을 받은 임상간호사들의 전문직 간 태도 및 교육부담감이 심폐소생 관련 자기효능감에 미치는 영향 (Impact of Inter-professional Attitude and Educational Burden on Clinical Nurses' Cardiopulmonary Resuscitation-related Self-efficacy Following Team-based Cardiopulmonary Resuscitation Simulation Training)

  • 옥종선;안수영;권정화
    • 근관절건강학회지
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    • 제31권1호
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    • pp.22-30
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    • 2024
  • Purpose: In-hospital cardiac arrest is rare, but often results in high mortality rates. Early and effective cardiopulmonary resuscitation (CPR) is crucial for survival and nurses are often the first responders. This study aimed to investigate how inter-professional attitudes and educational burdens affect self-efficacy related to CPR performance following team-based CPR simulation training. Methods: This retrospective observational study analyzed data from a satisfaction survey conducted after team-based CPR training sessions between January and November 2022. Of the 454 nurses surveyed, 238 were included in the study after excluding those with ambiguous responses. Multiple regression analysis was performed to assess factors influencing CPR self-efficacy. The factors examined included inter-professional attitudes and educational burden. Results: Higher levels of inter-professional attitudes, particularly regarding teamwork roles and responsibilities, lower educational burden, and a positive perception of CPR competence were all associated with improved CPR-related self-efficacy. Participants who reported higher engagement in teamwork, lower task load, and greater confidence in their CPR abilities demonstrated higher self-efficacy in performing CPR. Conclusion: Enhancing the competencies of nurses who may act as initial responders in CPR situations within or outside hospital settings can help save lives and support public health.

Volumetric CT Texture Analysis of Intrahepatic Mass-Forming Cholangiocarcinoma for the Prediction of Postoperative Outcomes: Fully Automatic Tumor Segmentation Versus Semi-Automatic Segmentation

  • Sungeun Park;Jeong Min Lee;Junghoan Park;Jihyuk Lee;Jae Seok Bae;Jae Hyun Kim;Ijin Joo
    • Korean Journal of Radiology
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    • 제22권11호
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    • pp.1797-1808
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    • 2021
  • Objective: To determine whether volumetric CT texture analysis (CTTA) using fully automatic tumor segmentation can help predict recurrence-free survival (RFS) in patients with intrahepatic mass-forming cholangiocarcinomas (IMCCs) after surgical resection. Materials and Methods: This retrospective study analyzed the preoperative CT scans of 89 patients with IMCCs (64 male; 25 female; mean age, 62.1 years; range, 38-78 years) who underwent surgical resection between January 2005 and December 2016. Volumetric CTTA of IMCCs was performed in late arterial phase images using both fully automatic and semi-automatic liver tumor segmentation techniques. The time spent on segmentation and texture analysis was compared, and the first-order and second-order texture parameters and shape features were extracted. The reliability of CTTA parameters between the techniques was evaluated using intraclass correlation coefficients (ICCs). Intra- and interobserver reproducibility of volumetric CTTAs were also obtained using ICCs. Cox proportional hazard regression were used to predict RFS using CTTA parameters and clinicopathological parameters. Results: The time spent on fully automatic tumor segmentation and CTTA was significantly shorter than that for semi-automatic segmentation: mean ± standard deviation of 1 minutes 37 seconds ± 50 seconds vs. 10 minutes 48 seconds ± 13 minutes 44 seconds (p < 0.001). ICCs of the texture features between the two techniques ranged from 0.215 to 0.980. ICCs for the intraobserver and interobserver reproducibility using fully automatic segmentation were 0.601-0.997 and 0.177-0.984, respectively. Multivariable analysis identified lower first-order mean (hazard ratio [HR], 0.982; p = 0.010), larger pathologic tumor size (HR, 1.171; p < 0.001), and positive lymph node involvement (HR, 2.193; p = 0.014) as significant parameters for shorter RFS using fully automatic segmentation. Conclusion: Volumetric CTTA parameters obtained using fully automatic segmentation could be utilized as prognostic markers in patients with IMCC, with comparable reproducibility in significantly less time compared with semi-automatic segmentation.

다태임신 감수술 (Multifetal Pregnancy Reduction) 후 완전태아손실에 영향을 미치는 인자 (Factors Affecting Complete Fetal Loss Following Multifetal Pregnancy Reduction)

  • 김혜옥;김문영;송현정;박찬우;허걸;김진영;양광문;유근재;송인옥;전종영;궁미경;강인수
    • Clinical and Experimental Reproductive Medicine
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    • 제30권1호
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    • pp.39-45
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    • 2003
  • Objective : To identify the factors affecting the complete fetal loss following multifetal pregnancy reduction (MFPR). Design: Retrospective clinical study. Methods : A total of 256 consecutive treatments of MFPR in IVF-ET cycles performed between 1992 through 2000 in Samsung Cheil hospital were analyzed. MFPR was done around 8 weeks of gestation by transvaginal ultrasono-guided aspiration in multiple pregnancies and reduced to singleton or twins. Stepwise logistic regression was performed to identify the factors affecting the final outcome of pregnancy after MFPR. Dependent variable was complete fetal loss and the independent variables were maternal age, paternal age, initial number of gestational sac (iGSNO), initial number of fetal heart beat, the number of remaining live fetus after MFPR, and chorionicity. Results: The total survival rate was 87.9%, and total fetal loss rate after MFPR was 12.1%. Total fetal loss occurred within four weeks from MFPR procedure was 1.95%. Total loss occurred after four weeks of procedure and before 24 gestational weeks was 8.2%. Seventy nine percent (202/256) of pregnancies delivered after 34 weeks of gestation. The survival rate of pregnancies reduced to singleton was significantly higher than that of pregnancies reduced to twins (93.5% vs. 86.7%, p<0.05). The mean ($\pm$SEM) gestational age at delivery was $36.2{\pm}1.0$ and $34.1{\pm}0.5$ weeks for pregnancies reduced to singletons and twins, respectively (p=0.065). Logistic regression analysis revealed that the maternal age, the number of initial gestational sac (iGSNO), and the number of remaining live fetus after MFPR significantly affected the rate of total fetal loss (Z = 0.174'age + 0.596'iGSNO + 1.324'remaining fetuses -12.07), (p<0.05). Conclusions: MFPR seems to be a relatively safe and efficient method to improve the obstetric outcome in high order multiple pregnancy. Because the maternal age, the number of initial gestational sac and the remaining live fetuses after MFPR affect the total fetal loss rate, restriction of the number of transferred embryos according to the age and MFPR to singleton fetus could be considered for the better obstetric outcome in IVF pregnancy.

복수가 있는 말기 암환자에서 복수 배액관 시술의 효과와 예후요인 분석 (Analysis of Effect and Prognostic Factors Associated with Catheter Intervention on Ascites in Terminal Cancer Patient)

  • 장명선;김철민;윤조히;라정란;장승남;김명옥;이자영
    • Journal of Hospice and Palliative Care
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    • 제19권4호
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    • pp.303-309
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    • 2016
  • 목적: 말기 암환자에서 악성 복수는 흔하게 발생하며, 그 자체가 나쁜 예후를 시사한다. 악성 복수에 대한 효과적이고, 최소한의 침습적인 방법으로 복수배액관 삽입이 제안되었다. 본 연구는 복수배액관 삽입을 시행한 말기 암환자들을 대상으로 복수배액관 시술의 효과와 부작용에 대하여 분석하고 시술 후 예후에 영향을 미치는 요인을 알아보기 위하여 시행되었다. 방법: 서울 소재 일개 3차 의료기관 호스피스 병동에 2010년 1월 1일부터 2013년 12월 31일까지 입원한 말기 암환자 2,608명 중 복수배액관 삽입을 시행한 67명의 환자들의 의무기록을 조사하였다. 인구학적 정보, 완화의료 수행지수, 혈액검사, 복수 배액관 유지 기간, 시술 합병증의 종류와 빈도, 항생제 사용 여부와 기간, 시술 후 생존기간을 분석하였다. 복수 배액관 삽입 후 생존기간에 영향을 미치는 요인을 평가하기 위해 단변량 및 다변량 콕스 비례위험 회귀분석을 실시하였다. 결과: 총 67명의 연구대상자 중 원발암은 간암 및 담도암과 위암이 가장 흔하였다. 복수배액관 시술 후 복수관련 증상의 호전은 55명(82.1%)에서 있었다. 시술 후 합병증은 통증(19.4%), 누수(14.9%), 배액관 빠짐(7.5%), 배액관 막힘(6%), 발열(4.5%)이었다. 복수배액관 시술 후 생존기간에 영향을 주는 인자는 다변량 콕스 비례위험 회귀분석 결과 완화의료 수행지수(HR 0.73; P=0.045), 저나트륨혈증(HR 2.77; P=0.003)이었다. 결론: 복수를 동반한 말기 암환자에서 복수 배액관 시술 시, 완화의료 수행지수와 저나트륨혈증은 예후 인자로 사용될 수 있을 것이다. 추후 대규모의 전향적 연구가 요구된다.