• 제목/요약/키워드: sun-exposure

검색결과 1,214건 처리시간 0.041초

Role of Vitamin D Deficiency and Lack of Sun Exposure in the Incidence of Premenopausal Breast Cancer: a Case Control Study in Sabzevar, Iran

  • Bidgoli, Sepideh Arbabi;Azarshab, Hamid
    • Asian Pacific Journal of Cancer Prevention
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    • 제15권8호
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    • pp.3391-3396
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    • 2014
  • Background: Vitamin D has been suggested as one of the critical factors for female reproductive health with protective activities against different cancers but there are conflicting facts regarding its role on breast cancer without any clear data on premenopausal cases. This study aimed to evaluate the role of vitamin D from dietary sources and sunlight exposure on the incidence of premenopausal breast cancer. Materials and Methods: We conducted a case control study on 60 newly diagnosed premenopausal breast cancer patients and 116 normal women who lived in Sabzevar and surrounding villages in Razavi, Khorasan, a rural and conservative area of Iran. Results: The mean concentrations of 25-OH vitamin D in cases and controls were $15.2{\pm}8.15$ vs $15.5{\pm}7/45ng/ml$, both well below normal values elsewhere. In fact 50% of analyzed individuals showed very severe or severe vitamin D deficiency and the rest (25%) were detected in suboptimal levels. Although the lack of vitamin D and calcium supplementation increased slightly the risk of premenopausal breast cancer (p=0.009, OR=1.115, CI 95%=1.049-1.187), higher prevalence of weekly egg consumption (86.66% vs 96.55%, p=0.023, OR=0.232, CI 95% 0.065-0.806) showed a slight protective role. The last but the most important risk factor was lack of sunlight exposure because the breast cancer patients had total body coverage from sun (p=0.007, OR=10.131, CI 98% 0.314-78.102). Conclusion: This study pointed out the role of vitamin D and other possible risk factors on the development and growth of breast tumors in this special geographical region. Although this study has revealed the interactions between hormonal and environmental factors in this province of Iran, understanding the deficiency pattern and its contribution to other lifestyle factors elsewhere is also necessary.

암모니아 급성노출에 따른 대왕범바리(Epinephelus fuscoguttatus ♀×E. lanceolatus ♂)의 혈액성상 및 혈장성분의 변화 (Changes of hematological parameters and plasma components in the hybrid grouper(Epinephelus fuscoguttatus ♀×E. lanceolatus ♂) by acute ammonia exposure)

  • 김광민;이희진;윤한빈;조재황;김석렬;이경미;김준환
    • 환경생물
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    • 제38권1호
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    • pp.40-46
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    • 2020
  • 본 실험에서 암모니아 급성 노출은 대왕범바리의 혈액학적 성상 및 혈장 성분에 유의적 변화를 나타내었다. 본 실험의 결과 20mg L-1 이상의 급성 암모니아 노출은 대왕범바리의 혈액학적 성상 및 혈장 성분에 영향을 주어 생리적 변화를 일으키며, 40mg L-1의 급성 암모니아 농도는 대량 폐사를 유발할 수 있음을 나타낸다. 향후 대왕범바리 바이오플락 양식기술 적용을 위한 양식연구에 이러한 결과를 지표로 활용할 수 있을 것이다.

현대패션에 표현된 여성인체 노출의 이미지에 관한 연구 (The Study on the Image of a Woman's Body Exposure Expressed in Modern Fashion)

  • 김선영
    • 복식
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    • 제57권1호
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    • pp.28-38
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    • 2007
  • This study is on the image of a woman's body exposure, expressed in various situations or images in the modern fashion. The results of this study can be summarized as the following. First, either the exposure or stress of a woman's specific body parts like breast, waist, hips, or legs which can be sensed totally different from man's or the ironic disclosure of body parts always lapped around emphasizes femininity by giving full play the unique sexual beauty of a woman's body. Second, the desire of disclosure to have others' attention with the concealment as suggestive exposure expresses the eroticism. The modified eroticism is found different from the conventional concept and is based on the desire to make others notice one's existence continually by the sexual exposure dress particularly to entire the other sex, the dismantlement of changing an underwear to an outer-dress, and so forth. Third, both exposure of a woman's sexual body parts and expression of exposure to the utmost by laying a woman's entire body bare can mean sex liberty in the laissez-faire generation. This may suggest a pleasure-oriented way of thinking of the self-consolation rather than showing others, or feature the personality and the liberty endowed women with.

해양 및 일반대기환경의 폭로실험에 의한 철근콘크리트구조물 보수재료.공법의 성능평가 및 철근의 부식특성에 관한 연구 (A Study on the Corrosion Properties of Reinforcing bar and Performance Evaluation of Repair Material and Method for Reinforced Concrete Structure by Exposure Experiment under the Coastal and Normal Atmosphere Environment)

  • 남정수;노경민;신승봉;김영선;김규용;김무한
    • 한국건축시공학회:학술대회논문집
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    • 한국건축시공학회 2006년도 춘계학술논문 발표대회 제6권1호
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    • pp.167-171
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    • 2006
  • In this study, for the establishment of the performance evaluation methods of repair material and method for reinforced concrete structure and the quality control standards of durability recovery method, the quantitative exposure data by exposure experiment under the coastal and normal atmosphere environment is accumulated and analyzed. Investigating and evaluating the result of exposure experiment during 30 months of exposure age under the coastal and normal atmosphere environment, carbonation depth and chlorideion penetration depth very little penetrated than cover depth. It seems reasonable to conclude that main cause of corrosion of reinforcing bar are inner chloride-ion and macro cell from the result of corrosion area and corrosion velocity. Accordingly, it is considered that fundamental data on the performance evaluation and quality control standards of repair material and method could be presented through continuous exposure test in the future.

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Subacute Nicotine Exposure in Cultured Cerebellar Cells Increased the Release and Uptake of Glutamate

  • Lim, Dong-Koo;Park, Sun-Hee;Choi, Woo-Jeoung
    • Archives of Pharmacal Research
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    • 제23권5호
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    • pp.488-494
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    • 2000
  • Cerebellar granule and glial cells prepared from 7 day-old rat pups were used to investigate the effects of sub-acute nicotine exposure on the glutamatergic nervous system. These cells were exposed to nicotine in various concentrations for 2 to 10 days in situ. Nicotine-exposure did not result in any changes in cerebellar granule and glial cell viability at concentrations of up to 500 $\mu\textrm{M}$. In cerebellar granule cells, the basal extracellular levels of glutamate, aspartate and glycine were enhanced in the nicotine-exposed granule cells. In addition, the responses of N-methyl-D-aspartate (NMDA)-induced glutamate release were enhanced at low NMDA concentrations in the nicotine-exposed granule cells. However, this decreased at higher NMDA concentrations. The glutaminase activity was increased after nicotine exposure. In cerebellar glial cells, glutamate uptake in the nicotine-exposed glial cells were either increased at low nicotine exposure levels or decreased at higher levels. The inhibition of glutamate uptake by L-trans-pyrollidine-2,4-dicarboxylic acid (PDC) was lower in glial cells exposed to 50 $\mu\textrm{M}$ nicotine. Glutamine synthetase activity was lower in glial cells exposed to 100 or 500 $\mu\textrm{M}$ of nicotine. These results indicate that the properties of cerebellar granule and glial cells may alter after subacute nicotine exposure. Furthermore, they suggest that nicotine exposure during development may modulate glutamatergic nervous activity.

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성인 초기의 태도, 주관적 규범, 자기효능감이 미세먼지 노출저감화행위에 미치는 영향 (The Influence of Attitude, Subjective Norm, and Self-efficacy on Prevention Behaviors of Particulate Matter (PM10-2.5) Exposure in Young Adults)

  • 신혜숙;지은선;구지현;김주희
    • 동서간호학연구지
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    • 제28권1호
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    • pp.41-48
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    • 2022
  • Purpose: The purpose of this study was to identify factors influencing prevention behaviors for particulate matter exposure in young adults. Methods: A convenience sample of 330 young adults was recruited from the community. Data were collected using a structured questionnaire and analyzed by descriptive statistics, t-test, ANOVA, Pearson's correlation coefficients, and stepwise multiple regression analysis with the SPSS/WIN 26.0 program. Results: The factors affecting prevention behaviors of particulate matter exposure were self-efficacy (β=.54 p<.001), subjective norm (β=.18, p<.001) and using the air purifier (β=.-17, p<.001). These variables had a 46% variance to explain prevention behaviors for particulate matter exposure. Conclusion: Findings showed that 'self-efficacy' and 'subjective norm' were important factors influencing prevention behaviors of particulate matter exposure in young adults. Thus, we need to consider the positive impact of prevention behaviors of particulate matter exposure and increase the chances of prevention behaviors of particulate matter exposure program for young adults.

샘플러를 통한 대기오염노출 평가와 건강영향 조사 (Investigation of Air Pollution Exposure and Health Effect Using Passive Sampler)

  • 이지나;허청송;임종한;최예용;김선태
    • Environmental Analysis Health and Toxicology
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    • 제19권2호
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    • pp.217-225
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    • 2004
  • In order to evaluate a health effect of air pollution, we designed exposure group (taxi driver, street sweeper, street trader,) and non -exposure group (office clerk). We analysed exposure and biologic marker by using personal sampler. Mean NO$_2$ and benzene level in each group were statistically significant. Also, respiratory symptom, chronic cough, sputum, and dyspnea on exertion were statistically significant in each group.