• Korean Journal of Biological Psychiatry
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• v.11 no.2
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• pp.110-116
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• 2004

Objectives:Recently, polymorphisms of several serotonin genes have been suggested to be associated with suicide, but the results are still unclear. We examined whether the T102C polymorphisms of the serotonin 2A receptor gene and the G861C polymorphisms of the serotonin 1B receptor gene were associated with suicidal behavior using drug intoxication. Methods:The subjects were 52 patients who visited emergency room with suicidal behaviors. Fifty controls were selected from healthy volunteers matched for sex and age to the suicide subjects. The polymorphisms were analyzed with TaqMan$^{(R)}$ assay using primers based on previous studies. Results:The T102C polymorphism of the serotonin 2A receptor gene showed no significant difference between the suicidal attempters and controls in both genotype and allele frequency analyses(p=0.179 and p=0.422, respectively). There was no statistically significant difference between the suicidal attempters and the controls in the G861C polymorphism of the serotonin 1B receptor gene and any significant effect of the genotype distributions or the allele frequencies was not observed(p=0.092 and p=0.987, respectively). Conclusion:These findings suggest that the T102C polymorphism in serotonin 2A receptor gene and the G861C polymorphism in serotonin 1B receptor gene are not related to the susceptibility to suicide attempts using drugs. To clarify the genetic influences of the serotonergic system on suicidal behavior, the polymorphisms of other candidate genes in the serotonergic system should be studied with larger numbers of subjects.

• Archives of Plastic Surgery
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• v.47 no.3
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• pp.250-255
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• 2020

Background Rosenthal et al. classified female, habitual, non-suicidal wrist cutters as a group and introduced the concept of wrist-cutting syndrome. We investigated the characteristics of wrist-cutting patients at our institution in comparison with results reported previously. Methods We conducted a retrospective study involving 115 patients who had cut their wrists and been examined at the emergency department of a single hospital in Seoul, Korea, between March 2014 and August 2018. Results There were more women (73 patients; 63.5%) than men (42 patients; 36.5%), and the women (mean age, 34.42 years) were significantly younger than the men (mean age, 50.07 years). The patients who had cut their wrists repeatedly were mainly women (22 of 26 patients; 84.6%); however, men caused more severe damage than women. Substance use before a suicide attempt did not significantly increase the severity of wrist cutting. Our institution planned and implemented a suicide prevention intervention program to improve the continuity of outpatient care. The number of patients who continued psychiatric treatment increased significantly after program completion. Conclusions We confirmed that most patients were young women who were not suicidal in the true sense because their wounds were not severe. Our study showed a protective role of the barrier tendons (flexor carpi radialis, palmaris longus, flexor carpi ulnaris), and we suggest careful repair of the barrier tendons to protect neurovascular structures against subsequent cutting events. We found that it was possible to improve the continuity of patient counseling by managing patients through a psychiatric treatment program.

• Journal of the Korean society of biological therapies in psychiatry
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• v.24 no.3
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• pp.163-172
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• 2018

Objectives : The aim of this study was to examine associations between quality of life in patients with schizophrenia and their family relationships. Methods : A total of 68 patients with schizophrenia participated in the study. Socio-demographic and clinical data were collected, as well as results from the Subjective Well-being under Neuroleptic Treatment Scale-Short Form(SWN-K), Family Emotional Involvement and Criticism Scale(FEICS), a visual analogue scale for evaluating the degree of perceived criticism(VAS), the Family Adaptability and Cohesion Evaluation Scale(FACES), Beck Cognitive Insight Scale(BCIS), and Rosenberg Self Esteem Scale(R-SES). Psychiatrists administered the Positive and Negative Syndrome Scale and the Calgary Depression Scale for Schizophrenia(CDSS), and collected a history of previous suicide attempts. Results : The SWN-K total scores showed significant negative correlations with scores on the FEICS perceived criticism, CDSS, and VAS measures and significant positive correlations with scores on the R-SES, FACES, and BCIS. Multiple regression analysis revealed that FEICS perceived criticism, FACES, and BCIS scores were significantly associated with SWN-K scores. The FACES total score was significantly lower in patients with a history of previous suicide attempt. Conclusion : The quality of life of patients with schizophrenia was negatively associated with greater perceived familial criticism and positively associated with better family cohesion and higher patient insight. In patients with a history of suicide attempts, family adaptability and cohesion were significantly low.

• Korean Journal of Psychosomatic Medicine
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• v.20 no.1
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• pp.40-49
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• 2012

Objectives : To examine emotional and psychological characteristics associated with suicide attempts in depressed patients. Methods : A sample of 37 inpatients diagnosed with major depressive disorder or depressive disorder NOS was divided into two groups : lifetime suicide attempters(N=15 ; 40.54%), non-attempters(N=22 ; 59.46%). Beck Depression Scale(BDI), Beck Anxiety Scale(BAI), Hamilton Depression Rating Scale(HDRS), Hamilton Anxiety Rating Scale(HARS), and MMPI-2 were used to evaluate symptoms severity and psychological characteristics. Results : Suicide attempters scored higher on the BDI though there were no group differences on the HDRS and on the both anxiety scales. Also they showed higher scores on the F, Fb, Pa, RC1, DEP, HEA, PK, AAS among MMPI-2 subscales. Our findings suggest that suicide attempters among depressed patients undergo more severe subjective distress and difficulties in adjustment than non-attempters. Also they were more hostile to others and showed lower trust. Lastly, they showed more somatic complaints and substance related problems. Conclusion : The present study showed that suicide attempters among depressed patients have distinct emotional and psychological characteristics. MMPI-2 would be helpful to assess suicidal risk of depressed patients.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.21 no.8
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• pp.304-314
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• 2020

This study examined the experiences of the suicide crisis and recovery process by elderly women living alone to identify the essential meaning and components of life as a life to live again. In addition, the recovery of the research participants, as well as the phenomenon of such changes in thought and life, were examined. The results of this study were as follows. Data analysis yielded four components, eight sub-components, and 16 semantic unit reductions. There were four components of suicide attempts and recovery experiences of elderly women. They were "disconnection and disqualification," "repeated hardships," "road of prosperity in trouble," and "generous tolerance." The essential topics of these components have emerged not as individual but as holistic and contextually connectable topics. Finally, to summarize the results, the essential semantic structure of the suicide attempt and recovery experience of elderly women living alone is a result of a dysfunctional social structure and environment, which has placed pressure on the life of research participants. As an alternative method to overcome, they tried to solve the problem through the extreme practice of suicide attempts, but positive energy to live again due to emotional recovery factors recognized through suicide failures have made it possible to cope with the difficult reality.

• The Journal of the Korea Contents Association
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• v.19 no.6
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• pp.644-654
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• 2019

The purpose of this study was to investigate the effects of depression, self-esteem and daily life ability on suicidal ideation in elderly people with chronic illness. The subjects were 170 outpatients and inpatients in a general hospital in D city. After conducting questionnaires for data collection, t-test, ANOVA and multiple regression analysis were performed and analyzed using SPSS 12.0 / win program. The results showed that suicidal ideation was influenced by gender, health status, chronic disease diagnosis, and experience of suicide attempt, with a positive correlation with depression and a negative correlation with daily life ability. The suicide attempt experience, depression, self-esteem and daily living ability showed 50.8% explanatory power against suicidal ideation. In order to reduce suicidal ideation, it is necessary to reduce suicidal ideation of elderly people with chronic diseases by managing an intervention program that reduces depression and improves daily life ability.

• Korean Journal of Biological Psychiatry
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• v.6 no.1
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• pp.81-88
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• 1999

Objectives : Significant progress has been made in understanding psychosocial, psychological, and environmental factors associated with suicide. However it is only recently that attention has been paid to the understanding of the neurobiology of suicide. The aim of this study was to examine the relationship between platelet serotonin level and suicidal behavior and psychological features of the suicidal attempters. Methods : After a suicidal attempt platelet serotonin level was measured from 21 patients and compared it with those from depression patients and normal controls. Also MMPI, HAM-D, Barratt impulsiveness scale(BIS) were done to evaluate their psychological features. Results : 1) There was no significant difference in sex ratio of the suicidal attempters. 2) There was no significant difference in platelet serotonin levels among three groups. 3) The analysis of MMPI revealed that the scores of D, Hs, Pt in clinical scales were significantly higher in suicide patients and scores of D, Pa, Si were in depression patients. 4) The HAM-D score was significantly higher in depression and suicide patients, especially in depression patients. 5) The analysis of Barratt impulsiveness scale revealed that the scores of nonplanning, motor and cognitive impulsiveness scale were significantly higher in suicide patients. Conclusions : There was no significant difference in platelet serotonin levels among three groups. However the analysis of psychological features revealed significant differences. Therefore we concluded that psychological examinations are benefit to evaluate the suicidal tendency.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.14 no.4
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• pp.1863-1870
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• 2013

The purpose of this study is when the cases will be found, used as a basic data for clinical severity prediction, and research on suicide prevention. By classifying the group of survival and death about the patients who visit the Emergency Medical Center by attempt suicide by drug addiction, identifying the condition when visiting and results of the treatment after visiting. From June 2009 to May 2011, last two years data that among the drug abusers who visited the Emergency Medical Center in C-University Hospital in Gwang-Ju, only suicidal patients, except with unintentional accidents were collected. The findings, among the drug addiction patients who high age, lower level of education and living alone were the mortality rate was higher. And if who drunk the agricultural chemicals, the convalescence was not good. If the causes of suicide were economic problems and depression, the mortality rate was higher. And when visit hospital, if the consciousness was stupor and semi-coma/coma, the convalescence was not good. As grasp the risk for suicide patients of drug addiction, help on the Prediction of clinical severity, also stamp the appropriate drug education with psychological support is more important on them.

• Journal of Korean Academy of Nursing
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• v.39 no.4
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• pp.459-468
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• 2009

Purpose: The purpose of the study was to investigate psychological factors such as eating psychopathology, depression, and obsessive-compulsion that might influence self-harm behavior in patients with eating disorders. Methods: Patients with eating disorders (n=135) who visited "M" clinic for eating disorders participated in the study. Data were collected from March to August 2007 using the Eating Disorder Inventory-2, Beck Depression Inventory, Maudsley Obsessional-Compulsive Inventory, and Self-Harm Inventory (SHI). Results: The participants scored high on self-harm as well as on depression and obsessive-compulsion. On the SHI, a high frequency of self harm behavior such as 'torturing self with self-defeating thoughts', 'abused alcohol', 'hit self', and 'suicide attempt' were found for the participants. There were significant correlations between most eating psychopathology variables, depression, obsessive-compulsion, and self-harm behavior. 'Interoceptive awareness' (eating psychopathology), depression, and 'checking' (obsessive-compulsion) were significant predictors of self-harm behavior. Conclusion: Future interventions for patients with eating disorders should focus on assessing the possibility of self-harm and suicidal attempts, especially in those patients with high levels of eating psychopathology, depression, or obsessive-compulsion. Early intervention for depression and obsessive-compulsion could contribute to preventing self-harm and suicide in patients with eating disorders.

• Research in Community and Public Health Nursing
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• v.24 no.2
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• pp.135-142
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• 2013

Purpose: The purpose of this study is to explore influencing factors which contribute to the suicidal ideation in community residents who have ever experienced suicidal attempts. Methods: The subjects of this study were a total of 165 local residents with some experiences of suicidal attempts in B City and K Province. The data were collected from May 1st to October 30th, 2012 and self-report questionnaires including Suicidal Ideation Inventory, Self-Esteem Inventory, Depression, Family and Social Support Inventory were used as a measurement tool. The data were analyzed using t-test, ANOVA, Pearson correlation coefficients, multiple regression with the SPSS/WIN 18.0 program. Results: The average score of suicidal ideation in the local residents with experiences of suicidal attempts was $12.7{\pm}6.25$. Predicted factors on suicidal ideation in the local residents with experiences of suicide attempts included self-esteem, depression and physical illness, and the suicidal ideation has a variance explanation power of 54%. Conclusion: The development and application of intervention programs, which can help to increase self-esteem levels and decrease depression levels among community residents with experiences of suicidal attempts, are first needed. Furthermore, nursing services of customized self-management for people with physical disabilities are needed on the basis of their own physical problems.