• 생약학회지
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• 제50권4호
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• pp.245-252
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• 2019

This study was initially explored to procure biomaterials capable of inhibiting cancer cell growth from nine Persicaria species (Polygonaceae). The extract of P. nepalensis that was selected from the initial screenings was further fractionated to identify bioactive compounds. The ethyl acetate (EtOAc) fraction was shown to be the most active in the inhibition of cell growth against six cancer cell lines (IC₅₀ value of 3.77-12.87 ㎍/ml). Phytochemical study led to the isolation of two galactolipids of 1,2-di-O-linolenoyl-3-O-β-D-galactospyranosyl-sn-glycerol (1) and 1-O-linolenoyl-3-O-β-D-galactospyranosyl-sn-glycerol (2) from the hexane fraction and three phenylpropanoyl sucroses of lapathoside A (3), vanicoside B (4) and lapathoside C (5) from the EtOAc fraction. These isolated compounds have not been reported from this plant. Compounds 3 and 4 exhibited the effective growth inhibition against a panel of cancer cell lines (IC₅₀ value of 6.90-18.09 μM). In addition, the anti-inflammatory activity was evaluated to determine lipopolysaccharide (LPS)-induced nitric oxide (NO) formation in RAW264.7 mouse macrophage cells. The EtOAc fraction (IC₅₀; 34.14 ㎍/ml) and its constituents, 3 (8.55 μM) and 4 (7.83 μM) were shown to be effective in the inhibition of LPS-induced NO production. Therefore, compounds 3 and 4 were considered to be active constituents for anti-inflammatory and antitumor activity from P. nepalensis.

• 분석과학
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• 제9권4호
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• pp.325-330
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• 1996

몸무우의 자엽에 저온과 polyamine(PA)을 처리하면 세포내의 환원당과 설탕의 농도가 증가되었고, 가을무우의 자엽에 저온처리를 하면 환원당과 설탕의 농도가 증가되나, 저온과 PA를 동시에 처리하면 세포내에 당류의 농도가 증가되지 않았다. 몸무우 자엽에서는 저온처리에 의해 총 아미노산의 농도는 증가되나, 가을무우에서는 증가되지 않았다. 이 결과는 저온에 예민한 봄무우는 세포내의 삼투조절에 의하여 적응하며, 봄무우와 가을무우 사이에 생리 및 생화학적인 대사가 다름을 보여 주었다. 저온에 예민한 봄무우에서 PA는 저온처리와 함께 상승효과를 보이나, 저온 스트레스에 강한 가을무우에서는 PA 처리로 상승효과를 나타내지 못함은 처음 보고 하는 결과이다.

• 한국분말야금학회:학술대회논문집
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• 한국분말야금학회 2006년도 Extended Abstracts of 2006 POWDER METALLURGY World Congress Part 1
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• pp.462-463
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• 2006

Monodispersed and nano-sized Ni powders were synthesized from aqueous nickel sulfate hexahydrate $(NiSO_4{\cdot}6H_2O)$ inside nonionic polymer network by using wet chemical reduction process. The sucrose was used as a nonionic polymer network source. The effect of reaction conditions such as the amount of sucrose and a various reaction temperature, nickel sulfate hexahydrate molarity. The influence of a nonionic polymer network on the particle size of the prepared Ni powders was characterized by means of X-ray diffraction (XRD), scanning electron microscopy (SEM), and particle size analysis (PSA). The results showed that the obtained Ni powders were strong by dependent of the reaction conditions. In particular, the Ni powders prepared inside a nonionic polymer network had smooth spherical shape and narrow particle size distribution.