• Title/Summary/Keyword: subjects with alcohol use disorders(AUDs)

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Alcohol Craving in Subjects with Alcohol Use Disorders in Response to Alcohol Cues (알코올 사용 장애자의 알코올 단서에 의해 유발된 갈망 특성)

  • Park, Mi-Sook;Sohn, Sun-ju;Park, Ji-Eun;Kim, Suk-Hee;Yu, In-Kyu;Sohn, Jin-Hun
    • Science of Emotion and Sensibility
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    • v.10 no.4
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    • pp.603-611
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    • 2007
  • Initially, this study was to develop reliable and effective alcohol-associated visual cues. Alcoholic picture cues were chosen from the Normative Appetitive Picture System (NAPS). Additional images consisted of Korean beer and mild liquor was pre-tested to select the pictures that would induce craving most intensely. The images that recorded the highest scores on a scale were chosen through the pre-test. And then, the reliability and validity were examined for the selected alcohol cues from NAPS and pre-test via another psychometric test. Secondly, the study was to investigate differences in craving between subjects with alcohol use disorders (AUDs) and non-alcoholic control subjects when exposed to the alcohol visual cues. Alcohol abusers with AUD (n=9) and demographically similar non-abusers (n=9) participated in this study. After given 5cc of alcohol, subjects were exposed to different types of stimuli (i.e., alcohol, nonalcoholic beverage, and visual control pictures and one rest (cross-hair)). Craving levels were rated through self-report on a Likert scale immediately after the presentation of visual cues. Results showed statistically significant differences between the AUD group and the control group in the Obsessive Compulsive Drinking Scale (OCDS) scores, pre-sip and post-sip alcohol craving. Also, the AUD group showed significantly a higher level of craving during alcohol cues compared to the control group. In conclusion, alcohol craving induced by alcohol cues among subjects with AUD was found to be different from that of non-abusers.

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Altered patterns of brain activity during transient anger among young males with alcohol use disorders: A preliminary study

  • Park, Mi-Sook;Sohn, Sunju;Seok, Ji-Woo;Kim, Eun-Hye;Sohn, Jin-Hun
    • Science of Emotion and Sensibility
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    • v.18 no.2
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    • pp.55-64
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    • 2015
  • The aim of the study was to investigate the neural substrates associated with processing anger among young males with alcohol use disorders (AUDs) using functional magnetic resonance imaging (fMRI). Eighteen individuals with AUD and 15 demographically similar non-abusers participated in the study. Participants were scanned on their brain functioning while they viewed an audio-visual film clip that was previously designed specifically to induce anger emotion, followed by anpsychological assessment. Greater brain activities were detected in the left inferior frontal gyrus (IFG) and dorsal anterior cingulate cortex (dACC) among subjects with AUD compared to the controls during the exposure to anger-provoking stimuli. Despite the same level of subjective anger during anger induction, the greater activations both in the IFG and dACC regions may suggestthat individuals with AUD have a greater propensity to undergo cognitive control and self-regulation while experiencing anger.