• Title/Summary/Keyword: sub-population

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Recent Changes of the Ethnic Korean Population in Yanbian Autonomous Prefecture: A Socio-demographic Approach (연변 조선족사회의 최근 변화: 사회인구학적 접근)

  • Kim Doo-Sub
    • Korea journal of population studies
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    • v.26 no.2
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    • pp.111-145
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    • 2003
  • This paper attempts to explore recent socio-demographic changes of the ethnic Korean population in Yanbian autonomous prefecture. Due to rapid decrease in the level of fertility and population ageing, Korean minority society in China has been in a process of profound transition after the introduction of the market economy and establishment of diplomatic relations between South Korea and China. The changes in demographic behaviors and in the structure of population appear to be much faster among Koreans than Hans. Results from the 2000 population census reveal that the Korean population in Yanbian, where ethnic Koreans are most densely populated in China, has been in a decreasing trends in absolute numbers and in its proportion to the total population. The growing tendency of regional mobility for work and for marriage, rapid expansion of residential areas, serious crisis of ethnic schools of Korean community, and weakening social integration and ethnic identification of Koreans in Yanbian are discussed in this study. It is expected that socio-demographic transition of Korean society in Yanbian will be even more drastic over the coming decades. The rapid changes in demographic behaviors and in the structure of population has major consequences and implications for every sphere of human life, and will present enormous challenges for the status of Korean minority society in China. Along with various statistical data on Yanbian, micro-level data as well as published reports from the 1990 Chinese population census for Yanbian and the 2000 Chinese population census are analyzed in this study. In addition to sex ratios and age ratios, various indices are calculated to analyze the characteristics and accuracy of the data from the 1990 and 2000 population censuses of China.

Electronic Structure and Chemical Bonding of La7Os4C9 (La7Os4C9의 전자구조와 화학결합)

  • Kang, Dae-Bok
    • Journal of the Korean Chemical Society
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    • v.53 no.3
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    • pp.266-271
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    • 2009
  • In the recently synthesized rare earth transition metal carbide $La_7O_{s4}C_9$ one finds one-dimensional organometallic $[O_{s4}C_9]^{21-}$ polymers embedded in a $La^{3+}$ ionic matrix. The electronic structure of the polymeric $[O_{s4}C_9]^{21-}$ chain was investigated by density of states (DOS) and crystal orbital overlap population (COOP), using the extended Huckel algorithm. A fragment molecular orbital analysis is used to study the bonding characteristics of the $C_2$ units in $La_7O_{s4}C_9$ containing $C_2$ units and single C atoms as well. The title compound contains partially filled Os and carbon bands leading to metallic conductivity. As the observed distances already indicated, the calculations show extensive Os-C interactions. The C-C bond distance in the diatomic $C_2$ units ($d_{C-C}$=131 pm) in the solid is significantly increased relative to $${C_2}^{2-}$$ or acetylene, because antibonding $1{\pi}_g$ orbitals are partially filled by the Os-$C_2(1\;{\pi}_g)$ bonding contribution found at and below the Fermi level.

Spatial Analysis on Mismatch Between Particulate Matter Regulation Services Supply and Demand in Urban Area - A Case Study of Suwon - (도시녹지 미세먼지 조절 서비스 수요와 공급의 공간적 차이 분석 - 수원시를 대상으로 -)

  • Kang, Da-In;Kwon, Hyuk-Soo;Choi, Tae-Young;Park, Chan;Kim, Sung-Hoon
    • Journal of the Korean Society of Environmental Restoration Technology
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    • v.24 no.2
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    • pp.57-69
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    • 2021
  • Urban green spaces supply ecosystem services (ESs), which are consumed by city residents and generate demand, to improve air quality. It is important to determine supply and demand for ESs and reduce the gap for efficient management. This study proposed a method to use the concept of supply and demand for ESs in the decision-making process for urban planning or management. PM10 concentrations were converted to weight for demand assessment on PM10 reduction, and PM10 absorption capacity of all green spaces including the forests, and that of urban green spaces excluding forests, was calculated for each supply assessment. The differences in the calculated supply and demand were analyzed to derive the mismatched regions in Suwon. As a result, regions with big forested areas showed sufficient supply, indicating that the degree of mismatch among administrative neighborhoods (dong) varied greatly depending on whether they had a forest. An analysis of only urban green spaces showed that all neighborhoods lacked supply. Forests with high PM10 absorption capacity had a great effect, but urban green spaces can be considered a key element in reducing PM10 in daily life. Considering the mismatch of supply and demand, spatial distribution, and population distribution, it is possible to prioritize the supply of urban green spaces to reduce PM10 and, furthermore, support decision making for priority zones subject to forest conservation and designation and cancellation of green spaces, which gives significance to this study.

PLK2 Single Nucleotide Variant in Gastric Cancer Patients Affects miR-23b-5p Binding

  • Dominkus, Pia Puzar;Mesic, Aner;Hudler, Petra
    • Journal of Gastric Cancer
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    • v.22 no.4
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    • pp.348-368
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    • 2022
  • Purpose: Chromosomal instability is a hallmark of gastric cancer (GC). It can be driven by single nucleotide variants (SNVs) in cell cycle genes. We investigated the associations between SNVs in candidate genes, PLK2, PLK3, and ATM, and GC risk and clinicopathological features. Materials and Methods: The genotyping study included 542 patients with GC and healthy controls. Generalized linear models were used for the risk and clinicopathological association analyses. Survival analysis was performed using the Kaplan-Meier method. The binding of candidate miRs was analyzed using a luciferase reporter assay. Results: The PLK2 Crs15009-Crs963615 haplotype was under-represented in the GC group compared to that in the control group (Pcorr=0.050). Male patients with the PLK2 rs963615 CT genotype had a lower risk of GC, whereas female patients had a higher risk (P=0.023; P=0.026). The PLK2 rs963615 CT genotype was associated with the absence of vascular invasion (P=0.012). The PLK3 rs12404160 AA genotype was associated with a higher risk of GC in the male population (P=0.015). The ATM Trs228589-Ars189037-Grs4585 haplotype was associated with a higher risk of GC (P<0.001). The ATM rs228589, rs189037, and rs4585 genotypes TA+AA, AG+GG, and TG+GG were associated with the absence of perineural invasion (P=0.034). In vitro analysis showed that the cancer-associated miR-23b-5p mimic specifically bound to the PLK2 rs15009 G allele (P=0.0097). Moreover, low miR-23b expression predicted longer 10-year survival (P=0.0066) in patients with GC. Conclusions: PLK2, PLK3, and ATM SNVs could potentially be helpful for the prediction of GC risk and clinicopathological features. PLK2 rs15009 affects the binding of miR-23b-5p. MiR-23b-5p expression status could serve as a prognostic marker for survival in patients with GC.

Material Life Cycle Assessments on Mg2NiHx-CaO Composites (Mg2NiHx-CaO 수소 저장 복합물질의 물질 전과정 평가)

  • HWANG, JUNE-HYEON;SHIN, HYO-WON;HONG, TAE-WHAN
    • Journal of Hydrogen and New Energy
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    • v.33 no.1
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    • pp.8-18
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    • 2022
  • With rapid industrialization and population growth, fossil fuel use has increased, which has a significant impact on the environment. Hydrogen does not cause contamination in the energy production process, so it seems to be a solution, but it is essential to find an appropriate storage method due to its low efficiency. In this study, Mg-based alloys capable of ensuring safety and high volume and hydrogen storage density per weight was studied, and Mg2NiHx synthesized with Ni capable of improving hydrogenation kinetics. In addition, in order to improve thermal stability, a hydrogen storage composite material synthesized with CaO was synthesized to analyze the change in hydrogenation reaction. In order to analyze the changes in the metallurgical properties of the materials through the process, XRD, SEM, BET, etc. were conducted, and hydrogenation behavior was confirmed by TGA and hydrogenation kinetics analysis. In addition, in order to evaluate the impact of the process on the environment, the environmental impact was evaluated through "Material Life Cycle Assessments" based on CML 2001 and EI99' methodologies, and compared and analyzed with previous studies. As a result, the synthesis of CaO caused additional power consumption, which had a significant impact on global warming, and further research is required to improve this.

Mediation of Gene Flow in Tropical Trees of Sub-Saharan Africa

  • Onokpise, Oghenekome U.;Akinyele, Adejoke O.
    • Journal of Forest and Environmental Science
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    • v.28 no.1
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    • pp.1-7
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    • 2012
  • Tropical forests whether fragmented or undisturbed or be they equatorial or deciduous, remain the storehouse of biodiversity for hundreds of thousands of plant and animal species. This unique characteristic continues to attract a wide range of scientists and international organizations to study and attempt to understand tropical forest ecosystems. Gene flow is mediated by pollen, seed and seedling dispersal, and factors affecting this gene flow include phenology, spatial distribution, population structures, seed predation, sexual and mating systems as well as physical and biological barriers to gene flow. Two methods are used in measuring gene flow: direct method that relies on the actual observation of seed and pollen dispersal, whereas indirect methods involve the use of genetic markers such as allozymes and DNA techniques. Political strife, extreme natural and artificial disasters, the lack of a comprehensive forestry research vision, coupled with difficult socio-economic conditions in Africa have made the environment quite difficult for sustained research activities on the part of those undertaking or wishing to undertake such studies. Gene flow studies in this region are few and far between. This review elaborates on the mechanisms of gene flow mediation in Sub-Saharan Africa.

Evaluation of Genetic Differentiation of Albizia lucida Populations from Eastern Region of the Indian Sub-continent by ISSR Markers

  • Aparajita, Subhashree;Rout, G.R.
    • Journal of Forest and Environmental Science
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    • v.24 no.1
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    • pp.27-34
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    • 2008
  • Level and distribution of genetic diversity in seven populations of Albizia lucida Benth. in eastern region of the Indian sub-continent were estimated using ISSR markers. Relatively higher level of genetic diversity within populations was observed in seven populations of A. lucida (mean of 0.38). From the result of AMOVA, majority of genetic diversity was allocated within populations (96.2%) resulting in a moderate degree of population differentiation. The observed distribution pattern of I-SSR variant among the populations was coincided with the typical pattern of long-lived woody tree species. Genetic relationships among the populations, reconstructed by UPGMA method, revealed two genetic groups. The population of Anugul and Bargarh turned out to be the most closely related despite a distance location between them. These formations will be of great value in the development of conservation plans for species exhibiting high levels of genetic differentiation due to fragmentation, such as indication of conservation unit size, which populations should be chosen as priority in conservation plans and which samples should be introduced in areas with a low number of individuals of A. lucida.

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Overexpression of p73 Enhances Cisplatin-Induced Apoptosis in HeLa Cells

  • Kim Keun-Cheol;Jung Chul-Soo;Choi Kyung-Hee
    • Archives of Pharmacal Research
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    • v.29 no.2
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    • pp.152-158
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    • 2006
  • To examine a possible synergistic role for p73 and cisplatin (cis-diamminedichloroplatinum II) in HeLa cells with a nonfunctional p53 protein, we established stable HeLa/p73 clones using a tetracycline inducible eukaryotic expression vector. The HeLa/p73 clones were not characterized by changes in growth or morphology. Cell death analysis, however, indicated a greater sensitivity to cisplatin in the p73-overexpressed HeLa cells than determined for the noninduced HeLa cells. This increased sensitivity seems to affect an induction of a sub-G1 population as assessed from flow cytometry analysis. The increased sub-G1 population may, in turn, result from a reduction of cyclin D1 and B1 expression by cisplatin in the presence of p73. Hoechest staining indicated an increased number of dead cells in the p73-induced cells compared to the non-induced cells. Poly ADP-ribose polymerase (PARP) cleavage was shown to be distinct in the p73-overexpressed cells compared to non-induced cells, which suggests that p73 modulates the cisplatin-induced apoptosis. Therefore, a synergistic effect of p73 and cisplatin to induce apoptosis could lead to new treatment for some types of human cancers.

Effects of persimmon leaf extracts on proteasome activity in HepG2 human liver cancer cells (감잎 추출물이 HepG2 인간 간암 세포의 proteasome 활성에 미치는 영향)

  • Kim, Soyoung;Yoon, Hyungeun
    • Korean Journal of Food Science and Technology
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    • v.51 no.4
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    • pp.393-397
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    • 2019
  • Proteasome inhibitors can promote apoptosis and cell cycle arrest in cancer cells by inhibition of nuclear factorkappaB ($NF-{\kappa}B$) activation. The purpose of this study was to investigate the effects of persimmon leaf extract (PSE) on proteasome activity in HepG2 human liver cancer cells. PSE treatment inhibited the proteasome activity and $NF-{\kappa}B$ activation in a dose-dependent manner in HepG2 human liver cancer cells (p<0.05). PSE treatment increased the population of cells in G2/M and sub-G1 phases. The results suggested that PSE is one of the candidate substances that may be developed into a proteasome inhibitor.

PDSO tuning of PFC-SAC fault tolerant flight control system

  • Alaimo, Andrea;Esposito, Antonio;Orlando, Calogero
    • Advances in aircraft and spacecraft science
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    • v.6 no.5
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    • pp.349-369
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    • 2019
  • In the design of flight control systems there are issues that deserve special consideration and attention such as external perturbations or systems failures. A Simple Adaptive Controller (SAC) that does not require a-priori knowledge of the faults is proposed in this paper with the aim of realizing a fault tolerant flight control system capable of leading the pitch motion of an aircraft. The main condition for obtaining a stable adaptive controller is the passivity of the plant; however, since real systems generally do not satisfy such requirement, a properly defined Parallel Feedforward Compensator (PFC) is used to let the augmented system meet the passivity condition. The design approach used in this paper to synthesize the PFC and to tune the invariant gains of the SAC is the Population Decline Swarm Optimization ($P_DSO$). It is a modification of the Particle Swarm Optimization (PSO) technique that takes into account a decline demographic model to speed up the optimization procedure. Tuning and flight mechanics results are presented to show both the effectiveness of the proposed $P_DSO$ and the fault tolerant capability of the proposed scheme to control the aircraft pitch motion even in presence of elevator failures.