• Proceedings of the Korean Information Science Society Conference
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• 2008.06a
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• pp.43-44
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• 2008

• Proceedings of the PSK Conference
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• 2003.04a
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• pp.236.2-237
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• 2003

Several studies of terbenzimidazoles and bibenzimidazoles suggested that benzimidazoles, especially 5-nitro-2-(para-methoxyphenyl)benzimidazole. possess topoisomerase I inhibition activities. In order to find out the structure activity relationship of 5-nitro-2-phenyl-benzimidazoles. eight derivatives that are substituted at the para position of 2-phenyl moiety were selected, synthesized ＆ evaluated considering their electronic or lipophilic parameters. (omitted)

• 한국생물공학회:학술대회논문집
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• 2000.11a
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• pp.479-479
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• 2000

• Proceedings of the Korean Society of Surveying, Geodesy, Photogrammetry, and Cartography Conference
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• 2003.04a
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• pp.443-450
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• 2003

Our country is constructed the digital map in the first NGIS plan. Through digital map construction, it was had the potentiality that can more easily activate GIS. But these data included numerous problems from user's view. In the second NGIS plan, our government try to construct the framework data for the maximization of GIS utilization. This paper is showed a step of update that considered relationship between the national framework data themes, suggested the structure of maintenance activity for national framework data.

• Proceedings of the Korean Society of Applied Pharmacology
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• 1993.04a
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• pp.39-39
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• 1993

To find out the novel anticancer agent for the treatment of solid tumors, 1-arylsulfonyl-2-alkoxy-4-arylimidazolines were designed and prepared from substituted styrenes through three steps. Compared to 5-fluorouracil, these analogues exhibit moderate cytotoxicity against human solid tumor cell lines, A-549(lung carcinoma) and SK-Mel-2(malignant melanoma). The structure-activity relationship indicates the high potential of this series for the development of novel antineoplastic agent.

• Journal of Marine Bioscience and Biotechnology
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• v.2 no.4
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• pp.201-208
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• 2007

Polychlorinated biphenyls (PCBs) are anthropogenic contaminants found globally in water, ice, soil, air and sediment. Modern analytical techniques allow us to determine these chemicals in environmental matrices at parts per trillion levels or lower. Environmental forensic on PCBs opens up new avenues of investigation such as transport and fate of water masses in oceans, sedimentation, onset of primary production, migration of marine mammals, their population distribution and pharmacokinetics of drugs inside organisms. By virtue of persistence, bioaccumulation, bioconcentration and structure-activity relationship PCBs emerge as unconventional chemical tracers of new sort.

• Proceedings of the PSK Conference
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• 2001.10a
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• pp.232.3-233
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• 2001

• Archives of Pharmacal Research
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• v.2 no.1
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• pp.71-78
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• 1979

Since the introduction of aspirin as a therapeutic agent in 1899, there have been numerous attempts at the improvement of its therapeutic value through molecular modification. These endeavors have centered mainly around the following two approaches : (a) improvement of the potency by introduction of a suitable group or groups on the benzene ring; and (b) modification of the carboxylic acid group, which is thought to be an immediate cause of the irritant effect.

• Proceedings of the PSK Conference
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• 2000.10a
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• pp.217.3-218
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• 2000

• Proceedings of the Korean Biophysical Society Conference
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• 1999.06a
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• pp.33-33
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• 1999

Mastoparan B (MP-B), an antimicrobial cationic tetradecapeptide amide isolated from the venom of the hornet Vespa basalis, is an amphiphilic ${\alpha}$-helical peptide. In order to study the relationship between the structure and biological activity, we used the three analogues by replacing amino acids with alanine (4LysAla： 4MP-B, 12-LYsAla: 12MP-B, 9TrpAla: 9Mp-B).(omitted)