• Title/Summary/Keyword: structure of space

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Structure-based Functional Discovery of Proteins: Structural Proteomics

  • Jung, Jin-Won;Lee, Weon-Tae
    • BMB Reports
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    • v.37 no.1
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    • pp.28-34
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    • 2004
  • The discovery of biochemical and cellular functions of unannotated gene products begins with a database search of proteins with structure/sequence homologues based on known genes. Very recently, a number of frontier groups in structural biology proposed a new paradigm to predict biological functions of an unknown protein on the basis of its three-dimensional structure on a genomic scale. Structural proteomics (genomics), a research area for structure-based functional discovery, aims to complete the protein-folding universe of all gene products in a cell. It would lead us to a complete understanding of a living organism from protein structure. Two major complementary experimental techniques, X-ray crystallography and NMR spectroscopy, combined with recently developed high throughput methods have played a central role in structural proteomics research; however, an integration of these methodologies together with comparative modeling and electron microscopy would speed up the goal for completing a full dictionary of protein folding space in the near future.

A Study on Spatial Construction of Tectonic in Russia Constructivism's Sculpture - Focused on the Milan Expo, 2015 Pavilion - (러시아 구성주의 조각의 텍토닉(Tectonic)적 공간 특성 - 밀라노 엑스포(Milan Expo, 2015) 파빌리온 중심으로 -)

  • Kim, Min-A;Lee, Chan
    • Korean Institute of Interior Design Journal
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    • v.24 no.6
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    • pp.107-118
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    • 2015
  • Today, The representation of the modern space is experimented with shape and surface of the de-structural point of view to make architecture and space, in terms of not being able to make defined by single regulation. However, it can correspond to the rapidly changing modern, but it is easy to fade of architecture fundamental meaning. Along with the need for the rise of the construction of fundamental space, should be built a 'tectonic' spatial, which is said to be building of logos. Tectonic, as norms for expressing the fundamental meaning of architecture, as to expression of construction, be unfolded with dualism such as science and art, technology and express, structure and formation, and it was introduced into the architecture through the construction expression of space that was a tectonic discussion of 19c german architects. On the other hand Constructivism which is avant-garde formative movement with Russia revolution, constructed 'sculpture' with the formative principles as tectonic. Tectonic's Formative characteristics can draw a conclusion with of tectonic characteristics of constructivism sculpture, space of logos will be realized through its study. Other hand, The pavilion, as symbol space, can be analyzed by tectonic properties, Pavilion, meaning the space is expressed in a variety of tectonic expression. As tectonic construction, fundamental ideology and symbolization of space is revealed metaphorically and visually.

A Study on the Iconological Approach of the Korean Traditional Space Design - Focusing on Regional Prototype and Creative Fantasy - (한국 전통공간디자인의 도상해석학적 접근에 관한 연구 - 지역적 원형과 창조적 환상의 개념을 중심으로 -)

  • Park, Kyung-Ae
    • Korean Institute of Interior Design Journal
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    • v.17 no.6
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    • pp.120-127
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    • 2008
  • Korean space design image is a kind of writing as well as one of the sign that dissembles itself as a direct transcript of what it represents. Moreover it is pictorial representation and notions such as mental and perceptual imaginary. Significance of Iconology lies in how we transform image and the imagination that produces it into power of trust and respect. From this point of view, the process of this study is illustrated as follows: At first, this study search out concept of archetype, collective unconsciousness and collective representation that found principles on basic theory for interpretation of korean space icon. Secondly, it mentions theoretical background of iconological contents and structure. And it clarifies Iconology as a method that is applicable logic for Korean space design. Finally, as an analysis of korean space design, this study analyse in three steps that are pre-iconological description, iconological analysis, iconological interpretation each in terms of modernization at regional korean space design. In the step of the pre-iconological description, it describe visual representative style based on era and place. In the step of the iconological analysis, the typical structure is classified in status, vernacular, ethnic, traditional. In the step of the iconological interpretation, connotation is categorized into allegory, multivalence, potential. Through this process, this study suggest that iconology is an appropriate analysis system of Korean space design images that represent symbols combined with our collective emotion.

Multi-Dimentional Scaling Analysis for Interior Space Planning Correponding to Korean Housing Behavior (한국인의 주거의식 행태에 순응하는 실내공간 계획을 위한 다차원 구조적 접근)

  • 이연숙;장순원;안지영
    • Korean Institute of Interior Design Journal
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    • no.1
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    • pp.52-55
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    • 1992
  • The purpose of this study was to suggest the spatial structure among residential behaviors in relation to work space. To find the structure, Multi-Dimensional Scaling analysis was used. Respondents were 349 middle income housewives living in apartments in the area of Caopital region. Data were collected through the questinnaire survey. For the future residential interior design, following points were sugtested. A laundary space neess to be developed independently , being separated from both bathroom and kitchen/dining space. A new area which will give housewives some territoriality and also function as home office needs to be considered. A space configuration which satisfies the organic relationships among laundary behaviors such as washing dying, ironing and folding , needs to be systematically planned, with two adjoining separate zones of wet and dry utility . The present bathroom nees to be more incorporated to the private bedroom rather than to workspace.

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Semi-supervised Multi-view Manifold Discriminant Intact Space Learning

  • Han, Lu;Wu, Fei;Jing, Xiao-Yuan
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • v.12 no.9
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    • pp.4317-4335
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    • 2018
  • Semi-supervised multi-view latent space learning is gaining considerable popularity recently in many machine learning applications due to the high cost and difficulty to obtain the large amount of label information of data. Although some semi-supervised multi-view latent space learning methods have been presented, there is still much space for improvement: 1) How to learn latent discriminant intact feature representations by employing data of multiple views; 2) How to exploit the manifold structure of both labeled and unlabeled point in the learned latent intact space effectively. To address the above issues, we propose an approach called semi-supervised multi-view manifold discriminant intact space learning ($SM^2DIS$) for image classification in this paper. $SM^2DIS$ aims to seek a manifold discriminant intact space for data of different views by making use of both the discriminant information of labeled data and the manifold structure of both labeled and unlabeled data. Experimental results on MNIST, COIL-20, Multi-PIE, and Caltech-101 databases demonstrate the effectiveness and robustness of our proposed approach.

A Study on the Principles of Extensive Connection in Psychological and Spatial Structure - Focused on the Extension Theory of Alfred North Whitehead - (심리적 공간구조의 연장적 결합원리 연구 - 화이트헤드의 연장이론을 중심으로 -)

  • Park, Kyoung-Ah
    • Korean Institute of Interior Design Journal
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    • v.20 no.6
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    • pp.79-87
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    • 2011
  • Spatial perception and spatial structure that focus on psychological effects produce a real force through the medium of space that can control human actions, even their psychology. The job of understanding the characteristics and effects of architectural spaces that recognize the relationship between architecture and human beings, including the psychological dimension, is an alternative search for quality spaces that can increase the mutual relationship between space and human beings. This paper introduces two propositions called "space" and "psychology" in order to discover a meta-pattern connecting space and the human mind with the aim of systematizing that internal network and establishing a new architectural system concerning space and human beings. This paper also proposes a method of accessing physical spaces that can affect psychological states through a conceptual substitution called "extension," with the aim of discovering the implications inherent in such extensive relationships and proposing a methodology of organizing psychological spaces based on the characteristics of that extensive connection. The means of extensively connecting psychological spaces were classified into the three categories of memory system, sensory system, and motor system, and their corresponding extensive connection characteristics called "simultaneous relativity," "non-mediated immediacy," and "purification process" were also derived. These characteristics accelerate the changes in psychological intensity and function as principles that organize psychological space.

Tomography Reconstruction of Ionospheric Electron Density with Empirical Orthonormal Functions Using Korea GNSS Network

  • Hong, Junseok;Kim, Yong Ha;Chung, Jong-Kyun;Ssessanga, Nicholas;Kwak, Young-Sil
    • Journal of Astronomy and Space Sciences
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    • v.34 no.1
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    • pp.7-17
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    • 2017
  • In South Korea, there are about 80 Global Positioning System (GPS) monitoring stations providing total electron content (TEC) every 10 min, which can be accessed through Korea Astronomy and Space Science Institute (KASI) for scientific use. We applied the computerized ionospheric tomography (CIT) algorithm to the TEC dataset from this GPS network for monitoring the regional ionosphere over South Korea. The algorithm utilizes multiplicative algebraic reconstruction technique (MART) with an initial condition of the latest International Reference Ionosphere-2016 model (IRI-2016). In order to reduce the number of unknown variables, the vertical profiles of electron density are expressed with a linear combination of empirical orthonormal functions (EOFs) that were derived from the IRI empirical profiles. Although the number of receiver sites is much smaller than that of Japan, the CIT algorithm yielded reasonable structure of the ionosphere over South Korea. We verified the CIT results with NmF2 from ionosondes in Icheon and Jeju and also with GPS TEC at the center of South Korea. In addition, the total time required for CIT calculation was only about 5 min, enabling the exploration of the vertical ionospheric structure in near real time.

A study on the ideological structure of palace space in Josun period (조선시대 궁궐공간의 관념적 구성에 관한 연구)

  • 김영모;최기수
    • Journal of the Korean Institute of Landscape Architecture
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    • v.25 no.4
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    • pp.141-157
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    • 1998
  • It has been general view to Josun palace space that the Kyongbok palace, a main palace, is arranged with symmetric geometrical composition principles and, unlikely main palace, sub-palaces such as Changduk, Changkyong and Kyonghee palace are placed in organic structure adapted to natural land form. With that view, there are no common factors to be considered between these palace, main and sub palace, in composting principles of the space. In this study, because of same ideological period, although there is external difference of that palaces, that common ideological principles are projected to these two palaces types through compositing space is assumed. On this hypostasis, this study has been focused on finding the ideological principles projected to these palace space commonly. As result of study, some of them are considered as common principles; Firstly, they are arranged in the text of contents through the way of naming to building, enterence and so on. The second point is ; it is viewed that the Oheung and symmetric arrangement method based on Oheung are used in compositing of palace space. The third is ; through analizing central space of Kyongbok palace, it is analized that oneness composition principles, which are based on the theory of Umyangheong, are projected to different palace space commonly.

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