• Wind and Structures
• /
• v.3 no.3
• /
• pp.143-158
• /
• 2000

This report presents the findings of a one-year monitoring effort to empirically characterize and evaluate the nature of near-ground winds for structural engineering purposes. The current wind engineering practice in the United States does not explicitly consider certain important near-ground wind characteristics in typical rough terrain conditions and the possible effect on efficient design of low-rise structures, such as homes and other light-frame buildings that comprise most of the building population. Therefore, near ground wind data was collected for the purpose of comparing actual near-ground wind characteristics to the current U.S. wind engineering practice. The study provides data depicting variability of wind speeds, wind velocity profiles for a major thunderstorm event and a northeaster, and the influence of thunderstorms on annual extreme wind speeds at various heights above ground in a typical rough environment. Data showing the decrease in the power law exponent with increasing wind speed is also presented. It is demonstrated that near-ground wind speeds (i.e., less than 10 m above ground) are likely to be over-estimated in the current design practice by as much as 20 percent which may result in wind load over-estimate of about 50% for low-rise buildings in typical rough terrain. The importance of thunderstorm wind profiles on determination of design wind speeds and building loads (particularly for buildings substantially taller than 10 m) is also discussed. Recommendations are given for possible improvements to the current design practice in the United States with respect to low-rise buildings in rough terrain and for the need to study the impact of thunderstorm gust profile shapes on extreme value wind speed estimates and building loads.

• Applied Biological Chemistry
• /
• v.42 no.4
• /
• pp.271-276
• /
• 1999

Several Streptomyces strains were tested for potent antifungal agents active against phytopathogenic fungi. Among the tested, S. hygroscopicus MJM1004 showed a potent antifungal activity when assayed using Candida albicans as indicator organism. With the strain of MJM1004, fermentation medium for the production of an antifungal agent was developed with varying carbon sources, nitrogen sources, and mineral elements, which resulted in the highest productivity in the medium containing 2% soybean meal, 1% glucose, 2% starch, 0.3% $CaCO_3$, 0.05% $MgSO_4{\cdot}7H_2O$, 0.05% $K_2HPO_4$. The active compound showed a broad spectrum of antifungal activity against several plant pathogenic fungi. The antifungal compound was purified and showed the physicochemical characteristics similar to azalomycin F complex in NMR and MS analysis.

• International Journal of Highway Engineering
• /
• v.20 no.2
• /
• pp.57-65
• /
• 2018

PURPOSES : The study aims to predict the service life of national highway asphalt pavements through deep learning methods by using maintenance history data of the National Highway Pavement Management System. METHODS : For the configuration of a deep learning network, this study used Tensorflow 1.5, an open source program which has excellent usability among deep learning frameworks. For the analysis, nine variables of cumulative annual average daily traffic, cumulative equivalent single axle loads, maintenance layer, surface, base, subbase, anti-frost layer, structural number of pavement, and region were selected as input data, while service life was chosen to construct the input layer and output layers as output data. Additionally, for scenario analysis, in this study, a model was formed with four different numbers of 1, 2, 4, and 8 hidden layers and a simulation analysis was performed according to the applicability of the over fitting resolution algorithm. RESULTS : The results of the analysis have shown that regardless of the number of hidden layers, when an over fitting resolution algorithm, such as dropout, is applied, the prediction capability is improved as the coefficient of determination ($R^2$) of the test data increases. Furthermore, the result of the sensitivity analysis of the applicability of region variables demonstrates that estimating service life requires sufficient consideration of regional characteristics as $R^2$ had a maximum of between 0.73 and 0.84, when regional variables where taken into consideration. CONCLUSIONS : As a result, this study proposes that it is possible to precisely predict the service life of national highway pavement sections with the consideration of traffic, pavement thickness, and regional factors and concludes that the use of the prediction of service life is fundamental data in decision making within pavement management systems.

• Applied Biological Chemistry
• /
• v.25 no.4
• /
• pp.224-231
• /
• 1982

${\alpha}-Tocopherol$ was found to be a fluorescent probe in determination of the phasetransition temperature of liposome. Since this was a discovery of a new aspect of ${\alpha}-tocopherol$ as an important biochemical molecule, its molecular spectroscopic characterization was carried out in order to obtain some informations on its spectral and, structural properties in various media, anticipating that the compound may entertain a wide applications in biochemical systems as a spectroscopic probe. Two species of α${\alpha}-tocopherol$, monomer and dimer, were found to exist in organic media, especially in solvents of nonhydrogen bonding ability. Monomer with maximum UV-absorption around $(291{\sim}294nm)$ is highly fluorescent, while dimer which is formed by intermolecular hydrogen bonds and absorbes with spectral peak at 298nm is nonfluorescent. ${\alpha}-tocopherol$ incorporated to liposome exhibits emission property quite different from that in various organic media showing broad and red-shifted fluorescence excitation and emission spectra. This spectral abnormality is to be interpreted to arise from chromanolate-type ion, H-dissociated ${\alpha}-tocopherol$.

• Bulletin of the Korean Chemical Society
• /
• v.28 no.12
• /
• pp.2209-2213
• /
• 2007

Ginseng has long been used as a traditional medicine in Asian countries including Korea and China. In recent years, it has been reported that the biological activities of ginseng are due to its active components, ginsenosides. Ginsenosides are represented by triterpenes of the dammarane type. Ginsenoside Re consists of two glucose rings, one rhamnose ring, and the triterpene ring. In the present study ginsenoside Re has been isolated from the Korean ginseng (Panax ginseng) and the tertiary structure has been determined using NMR spectroscopy. Flexibilities around each linkages described by seven torsion angles were considered. The structures of ginsenoside Re obtained by NMR spectroscopy show the rigidity around the glucopyranosyl ring II and alkene side chain. The dihedral angles of φ5, φ6, φ7 are about 150o, 50o and 45o, respectively. In addition, flexibility exists around rhamnopyranosyl and glucopyronosyl moiety. The linkage around the rhamnopyranosyl and glucopyranosyl ring I, are divided into three groups. This flexibility seems to play important role in regulation of the hydrophobic surface exposed to the solvent. Because of the growing need for the structural determination of ginsenoside, this result can help to understand their well-accepted pharmacological effects of ginsenoside Re.

• Bulletin of the Korean Chemical Society
• /
• v.32 no.9
• /
• pp.3372-3376
• /
• 2011

We have studied the relative stability and atomic structures of five $C_{20}X_2$ regioisomers obtained as diadducts of a $C_{20}$ cage (X = H, F, Cl, Br, and OH). All the regioisomers are geometric isomers, i.e., they differ in their spatial arrangement. Full-geometry optimizations of the regioisomers have been performed using the hybrid density-functional (B3LYP/6-31G(d, p)) method. Our results suggest that the cis-1 regioisomer (the 1,2-diadduct) is the most stable and that the second most stable is the trans-2 (1,13-diadduct) regioisomer, implying that the long-range interaction between the two adducts and the resonance effect are more pronounced than the diadduct-induced strain in the $C_{20}$ cage. The HOMO and LUMO characteristics of each regioisomer with the same symmetry of structural regioisomers except $C_{20}(OH)_2$ are topologically same. This suggests that by using an entirely different set of characteristic chemical reactions for each regioisomer, we can distinguish between the five regioisomers for each $C_{20}$ diadduct derivative.

• Journal of Korean Society of Steel Construction
• /
• v.21 no.4
• /
• pp.361-373
• /
• 2009

Using the genetic algorithm, the optimal-design technique of the Nielsen arch bridge was proposed in this paper. The design parameters were the arch-rise ratio and the steel weight ratio of the Nielsen arch bridge, and optimal-design techniques were utilized to analyze the behavior of the bridge. The optimal parameter values were determined for the estimated optimal level. The parameter determination requires the standardization of the safety, utility, and economic concepts as the critical factors of a structure. For this, a genetic algorithm was used, whose global-optimal-solution search ability is superior to the optimization technique, and whose object function in the optimal design is the total weight of the structure. The constraints for the optimization were displacement, internal stress, and time and space. The structural analysis was a combination of the small displacement theory and the genetic algorithm, and the runtime was reduced for parallel processing. The optimal-design technique that was developed in this study was employed and deduced using the optimal arch-rise ratio, steel weight ratio, and optimal-design domain. The optimal-design technique was presented so it could be applied in the industry.

• Journal of the Korean Geotechnical Society
• /
• v.30 no.4
• /
• pp.81-92
• /
• 2014

The integrity evaluation of river levee includes slope stability evaluation of riverside land and protected low-land, and safety of piping with respect to critical gradient and critical velocity based on related regulations, such as Design Criteria Rivers Commentary (2009), Structural Design Criteria Based Commentary (2009). The design hydro-graph is the most important design input factor for the integrity evaluation; it can be inaccurate due to the absence of its decision methods suggested by the national level. The authors in this paper evaluated numerical analytic levee integrity for piping and slope stability by changing each design hydro-graph, including rising ordinary water level, lasting flood water level, falling water level, and flood frequency for Mun-san-jae on Nak-dong River. Finally, the authors suggested that the levee integrity of piping and slope stability are very sensitive to the changes of increasing time of ordinary water level by 57 hours and lasting time of the flood water level by 53 hours, respectively, for Mun-san-jae.

• Journal of Korean Biological Nursing Science
• /
• v.3 no.2
• /
• pp.91-103
• /
• 2001

The bone is composed of the bone matrix of collagen and hydroxyapatite, the mixture of calcium and phosphours. The bone tissue is considered to the special connective tissue that possesses extracellular matrix made by collagen fiber deposited with mineral complex. In order to maintain bone mass measured by the sum of bone matrix and hydroxyapatite, bone resorption by osteoclast during lifetime and bone remodeling to form bone by osteoblast in its resorption region repeat continuously. The osteoblast has a mesodermic fetal origin like fibroblast for the formation of form tissues. Two cells express identical genes and synthesize the identical collagen type I as the major component of the formation of bone matrix and skin. Therefore, it is considered that the decrease of skinfold thickness and the decrease of bone mass related to the age, the change of two tissues composed of collagen type I is caused by the same genetic mechanism. The decrease of bone mass is caused by the change of the amount and structure of bone matrix by several factors and the amount of minerals deposited on bone matrix. Especially, in case of female, the deficiency of estrogen by menopause makes these changes rapidly increased. The decrease of bone mass and skinfold thickness is due to the decrease of the amount of collagen and its structural change the common component of bone tissue and skin tissue. Therefore, the relationship of the amount of cross-linked peptide N-telopeptide, collagen metabolite which excretes as urine. Based upon the proved results about the significant relationship of bone mass, the amount of bone collagen, the amount of skin collagen and skinfold thickness, the bone mass may be expected through a facile determination of skinfold thickness.

• Journal of the Korea Concrete Institute
• /
• v.28 no.4
• /
• pp.427-434
• /
• 2016

The purpose of this study is to propose a mixture proportioning approach based on the replacement level of natural sand for reducing $CO_2$ emissions from artificial lightweight aggregate concrete(LWAC) production. To assess the effect of natural sand on the reduction of $CO_2$ emissions and compressive strength of LWAC, a total of 379 specimens compiled from different sources were analyzed. Based on the non-linear regression analysis using the database and the previous mixture proportioning method proposed by Yang et al., simple equations were derived to determine the concrete mixture proportioning and the replacement level of natural sand for achieving the targeted performances(compressive strength, initial slump, air content, and $CO_2$ reduction ratio) of concrete. Furthermore, the proposed equations are practically applicable to straightforward determination of the $CO_2$ emissions from the provided mixture proportions of LWAC.