• Bulletin of the Korean Chemical Society
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• v.32 no.10
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• pp.3675-3681
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• 2011

Fusarium oxysporum, an important pathogen that mainly causes vascular or fusarium wilt disease which leads to economic loss. Disruption of gene encoding a heterotrimeric G-protein-${\beta}$-subunit (FGB1), led to decreased intracellular cAMP levels, reduced pathogenicity, colony morphology, and germination. The plant defense protein, Nicotiana alata defensin (NaD1) displays potent antifungal activity against a variety of agronomically important filamentous fungi. In this paper, we performed a molecular modeling and docking studies to find vital amino acids which can interact with various antifungal compounds using Discovery Studio v2.5 and GRAMMX, respectively. The docking results from FGB1-NaD1 and FGB1-antifungal complexes, revealed the vital amino acids such as His64, Trp65, Ser194, Leu195, Gln237, Phe238, Val324 and Asn326, and suggested that the anidulafungin is a the good antifungal compound.The predicted interaction can greatly assist in understanding structural insights for studying the pathogen and host-component interactions.

• Journal of the Korean Society of Propulsion Engineers
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• v.21 no.3
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• pp.56-60
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• 2017

In hypersonic aircraft, increase of aerodynamic heat and engine heat leads heat loads in airframe. It could lead structural change of aircraft's component and malfunctioning. Endothermic fuels are liquid hydrocarbon fuels which are able to absorb the heat load by undergoing endothermic reactions. In this study, exo-tetrahydrodicyclopentadiene was selected as a model endothermic fuel and experiments were investigated in endothermic fuel cooling system with zeolite catalyst. Three shapes of catalysts have been manufactured and endothermic characteristics were recovered. Bineded catalyst showed higher heat absorption and conversion than other two zeolite catalysts. In product distribution, binded catalyst showed higher aromatics composition.

• Wind and Structures
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• v.13 no.5
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• pp.413-431
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• 2010

The focus of this article is on the assessment of vertical wind vector components and their aerodynamic impact on lattice framework, specifically two distinct sections of a guyed transmission tower. Thunderstorm winds, notably very localized events such as convective downdrafts (including downbursts) and tornadoes, result in a different load on a tower's structural system in terms of magnitude and spatial distribution when compared to horizontal synoptic winds. Findings of previous model-scale experiments are outlined and their results considered for the development of a testing rig that allows for rotation about multiple body axes through a series of wind tunnel tests. Experimental results for the wind loads on two unique experimental models are presented and the difference in behaviour discussed. For a model cross arm with a solidity ratio of approximately 30%, the drag load was increased by 14% when at a pitch angle of $20^{\circ}$. Although the effects of rotation about the vertical body axis, or the traditional 'angle of attack', are recognized by design codes as being significant, provisions for vertical winds are absent from each set of wind loading specifications examined. The inclusion of a factor to relate winds with a vertical component to the horizontal speed is evaluated as a vertical wind factor applicable to load calculations. Member complexity and asymmetric geometry often complicate the use of lattice wind loading provisions, which is a challenge that extends to future studies and codification. Nevertheless, the present work is intended to establish a basis for such studies.

• Journal of the Earthquake Engineering Society of Korea
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• v.8 no.6 s.40
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• pp.13-22
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• 2004

Ductiluty factor has played an important role in seismic design as it is key component of response modification factor(R). In this stuty, ductility factors() are calculated by multiplying ductility factor for SDOF systems() and MDOF modification factors(). Ductility factors() for SDOF systems are computed from nonlinear dynamic analysis undergoing different level of displacement ductiluty demands and period when subjected to a large number of recorded earthquake ground motions. The MDOF modification factors() are proposed to account for the MDOF systems, based on previous studies. A total of 108 prototype steel frames are designed to investigate the ductility factors considering the number of stories(4, 8 and 16-stories), framing system(Perimeter Frames, PF and Distributed Frames, DF), failure mechanism(Strong-Column Weak-Beam, SCWB and Weak-Column Strong-Beam, WCSB), soil profiles(SA, SC and SE in UBC 1997) and seismic zone factors(Z=0.075, 0.2 and 0.4 in UBC 1997). It is shown that the number of stories, failure mechanisms (SCWB, WCSB), and soil profiles have great influence on the ductility factors, however, the structural system(Perimeter frames, Distributed frames), and seismic zones have no influence on the ductility factors.

• Management & Information Systems Review
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• v.31 no.4
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• pp.377-395
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• 2012

The purposes of this research was to examine the relationship between two forms of satisfaction, commitment and turnover intentions at organization, job. Also consistent with the Meyer et al(1993) notion of the three-component model of organizational commitment. Although researchers have examined organizational commitment in relation to a wide range of variables, there has been no discriminant validity of commitment at occupation and job. The purpose of the present article, are to compare the relation between satisfaction forms, commitment forms and turn intentions forms. Confirmatory factor analysis supported the proposed distinction between the three forms of commitment and two turnover intentions forms at the measurement level in the distribution industry(N=156). Results using structural equation analysis with AMOS18 showed that job satisfaction had an positive impact on job commitment forms. Organizational satisfaction positive impact on two turnover intentions forms. However it revealed that no significant relation between organizational satisfaction and job commitment, job commitment and job turnover intentions.

• Journal of Periodontal and Implant Science
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• v.30 no.1
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• pp.51-65
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• 2000

Extracellular matrix component is degraded by enzymes of thematrix metalloproteinases(MMPs). MMPs are produced by both hemopoietic and structural cells. Increased activity of MMP-3 in periodontium is strongly associated with inflammatory periodontal disease. The purpose of the present study was to estimate the effect of BMP-7 on regeneration of periodontium. The optical density was measured by microwell plate reader at 450 nm.The difference of the optical density and the relative activity ofMMP-3 according to the concentration were statistically analyzed by one way ANOVA. The results were as follows: 1. Tetracycline-HCl showed the tendency to inhibit the activity of MMP-3 at the concentration lower than $25{\mu}g/ml$. 2. Doxycycline-HCl inhibited significantly the activity of MMP-3 at the concentration lower than $100{\mu}g/ml$. 3 . Minocycline-HCl inhibited the activity of MMP-3 at the concentration in the range of 10 to 200${\mu}g/ml$. Within the limit of the present study, the above results suggested that bone morphogenetic protein-7 may play a important role in development of periodontium.

• Current Industrial and Technological Trends in Aerospace
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• v.9 no.1
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• pp.119-129
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• 2011

The soft landing of a lunar lander after the entrance of lunar orbit is an essential prerequisite for the accomplishment of the lander's lunar mission. During the landing process of a lunar lander, efficient shock absorption and stability maintenance are indispensible technology to protect payloads. Therefore, the landing gear is a crucial structural component of a lunar lander, it has to absorb the kinetic energy associated with touchdown and support the static load of the landing module in an upright position. In this paper, various landing gears of lunar landers which are being developed as well as which had been successfully landed on the moon surface are investigated. In the end, the Korean lunar lander, which is being designed for preliminary development model, is presented as an example of the lunar lander development.

• Bulletin of the Korean Chemical Society
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• v.27 no.11
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• pp.1801-1808
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• 2006

The interaction between whey carrier protein $\beta$-lactoglobulin type A and B (BLG-A and -B) and 2,2'-bipyridin n-hexyl dithiocarbamato Pd(II) nitrate (BPHDC-Pd(II)), a new heavy metal complex designed for anticancer property, was investigated by fluorescence spectroscopy combined with chemometry and circular dichroism (CD) techniques. A strong fluorescence quenching reaction of BPHDC-Pd(II) to BLG-A and -B was observed. Hence, BPHDC-Pd(II) complex can be bound to both BLG-A and -B, and quench the fluorescence spectra of the proteins. The quenching constant was determined using the modified Stern-Volmer equation. The binding parameters were evaluated by fluorescence quenching method. The results of binding study provided evidences presence of two and three sets of binding sites on the BLG-B and -A, respectively, for BPHDC-Pd(II) complex. Using fluorescence spectroscopy and chemometry, the ability of BLG-A and -B to form an intermediate upon interaction with BPHDC-Pd(II) complex was assessed. CD studies displayed that under influence of different concentrations of BPHDC-Pd(II) complex, the regular secondary structure of BLG-B had no significant changes, whereas for BLG-A a transition from $\alpha$-helix to $\beta$-structure was appeared. The results for both of BLG-A and -B displayed that BPHDC-Pd(II) complex can induce a conformational transition from the native form to an intermediate state with a slightly opened conformation, which is detectable with chemometry analyses.

• Structural Engineering and Mechanics
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• v.55 no.4
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• pp.765-784
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• 2015

Connections are usually designed either as pinned usually associated with simple construction or rigid normally is associated with continuous construction. However, the actual behaviour falls in between these two extreme cases. The use of partial strength or semi-rigid connections has been encouraged by Euro-code 3 and studies on semi-continuous construction have shown substantial savings in steel weight of the overall construction. Composite connections are proposed in this paper as partial or full strength connections. Standardized connection tables are developed based on checking on all possible failure modes as suggested by "component method" for beam-to-column composite connection on major axis. Four experimental tests were carried out to validate the proposed standardised connection table. The test results showed good agreement between experimental and theoretical values with the ratio in the range between 1.06 to 1.50. All tested specimens of the composite connections showed ductile type of failure with the formation of cracks occurred on concrete slab at maximum load. No failure occurred on the Trapezoidal Web Profiled Steel Section as beam and on the British Section as column.

• Smart Structures and Systems
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• v.12 no.3_4
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• pp.251-269
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• 2013

Measurement of deflections of certain bridges is usually hampered by corruption of the GPS signal by multipath associated with passing vehicles, resulting to unrealistically large apparent displacements. Field data from the Gorgopotamos train bridge in Greece and systematic experiments revealed that such bias is due to superimposition of two major effects, (i) changes in the geometry of satellites because of partial masking of certain satellites by the passing vehicles (this effect can be faced with solutions excluding satellites that get temporarily blocked by passing vehicles) and (ii) dynamic multipath caused from reflection of satellite signals on the passing trains, a high frequency multipath effect, different from the static multipath. Dynamic multipath seems to have rather irregular amplitude, depending on the geometry of measured satellites, but a typical pattern, mainly consisting of a baseline offset, wide base peaks correlating with the sequence of main reflective surfaces of the vehicles passing next to the antenna. In cases of limited corruption of GPS signal by dynamic multipath, corresponding to scale distortion of the short-period component of the GPS waveforms, we propose an algorithm which permits to reconstruct the waveform of bridge deflections using a weak fusion of GPS and RTS data, based on the complementary characteristics of the two instruments. By application of the proposed algorithm we managed to extract semi-static and dynamic displacements and oscillation frequencies of a historical railway bridge under train loading by using noisy GPS and RTS recordings. The combination of GPS and RTS is possible because these two sensors can be fully collocated and have complementary characteristics, with RTS and GPS focusing on the long- and short-period characteristics of the displacement, respectively.