• 한국광학회지
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• 제14권3호
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• pp.219-223
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• 2003

광섬유의 잔류응력(residual stress)을 측정하기 위해 위상보정 편광기(polariscope)를 새롭게 구성하고, 간섭이나 회절에 대한 영향을 최소화시키면서 빠르고 정확하게 측정하는 방법을 제시하였다. 이 방법을 이용하여 일반 광섬유의 잔류 응력 분포를 측정할 수 있었다. 또한 광섬유의 잔류응력이 모재의 잔류응력분포와 달리 인출 시 발생하는 광섬유 내 온도의 냉각곡선에 밀접한 관계를 갖고 있음을 알 수 있었다.

• 대한한의학방제학회지
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• 제10권2호
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• pp.57-72
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• 2002

To investigate the effect of Qi promoting-agents, clearing heat of deficiency type-agent, clearing heat of excessive type-agent, warming interior part of body-agent and Shihoieokgan-Tang against the immobilization stress, Cypri Rhizama, Auranti pericarpium, Aucklandiae Radix and Bupleuri Radix, Soyo-San, Hwangyeonhaedok-Tang, Geongangbuja-Tang and Shihoieokgan-Tang was administered intragastically 1hr prior to immobilizaiton stress and the change of corticosterone level has been measured by the flurometric method. The results obtained are as follows: 1. Qi promoting-agents(Cypri Rhizama, Auranti pericarpium, Aucklandiae Radix and Bupleuri Radix) showed mildly reducing effect or did not shown the reducing effect against the elevated coritocostereone level induced by the immobilization stress in the mice. 2. Hwangyeonhaedok-Tang, Gungangbuza-Tang, and Soyo-San did not show the reducing effect against the elevated corticostereone level induced by the immobilization stress in the mice. 3. Shihoieokgan-San was effective against the elevated corticosterone level induced by the immobililzation stress at 1g／kg, 3g／kg respectively. Consequently these data proved that Qi pomoting-agents as single herb(Cypri Rhizama, Auranti pericarpium, Aucklandiae Radix and Bupleuri Radix), clearing heat of deficiency type-agent(Soyo-San), warming interior part of the body(Gungangbuza-Tang), clearing heat of excessive type-agent(Hwangyeonhaedok-Tang) have no effect to decrease the elevated corticosterone level in mice exposed to the immobilization stress. Therefore our study revealed that Shihoieokgan-San which has the effects of herbs and formulae mentioned above decreased the elevated corticosterone level in mice exposed to the immobilization stress significantly.

• 대한기계학회논문집
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• 제15권2호
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• pp.404-412
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• 1991

In the design of high speed machinery, designers must consider the problem of possible structural failure due to excessive dynamically varying stresses, which are induced by the varying external loads and internal inertia forces, in the links of the mechanism. A study of the dynamically induced stresses would indicate what values of the minimum permissible fatigue strength should be for safe mechanism operation. This paper investigates the nature of the stress fluctuation in high speed mechanism on the basis of the effects of both the loads and the friction. The latter is apt to be neglected in the usual analysis in spite of the fact that it is always generated in the operating machinery. The analysis is performed on the coupler of the slider-crank mechanism for illustrative purposes and the results are expressed in a non-dimensional form for design applications.

• 한국해양공학회지
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• 제16권4호
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• pp.32-36
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• 2002

In this paper, a numerical methodology for health monitoring of weldment was proposed using finite element method coupled with continuum damage mechanics. The welding-induced residual stress distribution of T-joint weldment was calculated using a commercial finite element package SYSWELD+. The distribution of latent damage was evaluated from the stress and strain components taken as the output of a finite element calculation. Numerical examples were given to demonstrate the usefulness of this so-called "post-processing approach" in the case of welding-induced damage assessment.

• Nuclear Engineering and Technology
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• 제30권3호
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• pp.212-221
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• 1998

In the present study, a method for the dynamic analysis of a reactor core is developed. Peak responses for the motions induced from earthquake are obtained for a core model. The dynamic responses such as fuel assembly shear force, bending moment, axial force and displacement, and spacer grid impact loads are investigated. Prediction of fuel assembly stress during an earthquake requires development of a fuel assembly stress analysis model capable of interfacing with the models and results discussed in the dynamic analysis of a reactor core. This analysis uses beam characteristics which describe the overall fuel assembly response. The stress analysis method and its application for the case of an increased seismic level are also presented.

• 한국마이크로전자및패키징학회:학술대회논문집
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• 한국마이크로전자및패키징학회 2002년도 추계기술심포지움논문집
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• pp.137-142
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• 2002

This paper deals with the stress singularity induced at the interface corner between the elastic substrate and the viscoelastic thin film as the polymeric film absorbs moisture from the ambient environment. The boundary element method is employed to investigate the behavior of Interface stresses. The order of the singularity is obtained numerically for a given viscoelastic model. It is shown that the stress singularity factor is relaxed with time, while the order of the singularity increases with time for the viscoelastic model considered.

• Journal of Welding and Joining
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• 제31권2호
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• pp.43-48
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• 2013

This paper Investigated the characteristics of residual stress in weld is composed of typical specimens, are investigated by using three dimensional thermal elasto-plastic FEM analysis. Numerically calculated residual stresses in the gas welds were then compared with experimental results obtained by the hole-drilling method. Using the stress amplitude (${\sigma}a$)R at the hot spot point of gas weld, the relations obtained as the fatigue test results for typical specimens having various dimensions and shapes were systematically rearranged to obtain the (${\sigma}a$)R-Nf relationship. It was found that more systematic and accurate evaluation of the fatigue strength of plug- and ring-type gas-welded joints can be achieved by using (${\sigma}a$)R.

• 대한치과보철학회지
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• 제31권4호
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• pp.679-686
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• 1993

The osseointegrated implant conducts the stress directly to the bone due to lack of cushoning effect of periodontal ligament. So, the design and material quality of superstructure plays an important role in resolution and diffusion of stress. Recently, the various superstructures have been developed to improve esthetics and resolve various complicated conditions. The purpose of this study was to evaluate the stress induced by various system on the osseointegrated implant using UCLA abutment, EsthetiCone abutment, Anatomic abutment as well as Branemark conventional abutment. The stress distribution was evaluated by the photoelastic method which can simultaneously observe all around stress distribution. The superstructures embedded in epoxy resin specimen were loaded at various angle with a force of 15Kg to analyse the stress distribution of the fixture. The results of this study were obtained as follows : 1. Under vertical loading, the large and broad stress was distributed below the fixture in all systems. 2. The fringe order of the stress was increased in proportion to tillting the specimen. The largest stress was shown in 25 angled degree tilting case. 3. The Branemark conventional abutment showed the lowest value, and EsthetiCone abutment, Anatomic abutment and UCLA abutment showed the stress value in accending order.

• 대한약리학회지
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• 제19권2호
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• pp.45-55
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• 1983

뇌내 여러 신경전달물질계가 시상하부-뇌하수체-부신계(HPA)를 복잡하게 조절하고 있다는 증거가 많이 나오고 있다. 그 중에서도 5-HT(Serotonin)계의 stress시의 역할에 대해서는 많은 연구가 있어왔으나 아직 논란이 많이 제기되고 있다. 따라서 저자는 5-HT가 stress시 HPA axis를 조절하는데 필수적인 역할을 하는가를 말아보기 위해서 1) Stress전후에 5-HT의 steady state농도와 5-HT의 교체율(turnover rate) 및 합성율(synthesis rate)을 측정해 보았으며 2) 비교적 5-HT계에 특이하게 작용하는 여러 약물들을 주사한 후에 stress 반응을 측정해 보았다. 1) 1분간 ether stress 가한 직후에 시상하부와 다른 뇌부위에서의 5-HT와 5-HIAA농도는 즉각적으로 의미있게 상승하였으나 혈장 corticosterone농도는 즉각상승을 보이지 않다가 2분후에 상승을 보였다. 2) Stress(30분 immobilization & 1분 ether stress)가한 백서에서는 시상하부와 다른 뇌부위에서 5-HT합성을 혹은 교체율이 2배-4배까지 상승하였다. 3) 5-HT합성 전구물질(L-tryptophan)과 수용체 자극제 (5-MeODMT)를 투여하였을 때는 투여용량에 비례해서 혈장 corticosterone함량이 상승하였다. 4) L-tryptophan과 MAO억제제 (pargyline) 혹은 L-tryptophan과 5-MeODMT의 병합 투여로 stress시 혈장 corticosterone의 상승이 더 높게 나타났다. 5) 5-HT 합성억제제(PCPA), 5-HT 신경독약(5,7-DHT)을 투여하고 stress를 가하였을 때는 시상하부와 다른 뇌 부위에서 5-HT의 하강이 별로 나타나지 않았으며, 동시에 혈장 corticosterone의 하강도 의미있게 나타나지 않았다. 그러나 midline raphe핵을 파괴하였을 때는 5-HT와 corticosterone의 하강이 나타났다. 6) 비교적 특이하게 serotonin제에 작용하는 여러 약물들을 투여한 후에 나타나는 5-T와 혈장 corticosterone함량 사이에는 상당히 높은 양의 상관관계계가 있었다(r>0.81). 이상의 결과를 종합해 볼때 serotonin(5-HT)은 시상하부-뇌하수체-부신계의 스트레스반응조절에 중요한 자극적 역할을 하리라고 생각된다.

• Mass Spectrometry Letters
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• 제14권3호
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• pp.91-103
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• 2023

As one of the most common mood disorders, numerous studies have shown depression is the main risk factor for non-suicidal self-harm. The pathogenesis of depression is complex, and a comprehensive and rapid measurement of monoamine neurotransmitters and their metabolites will be very helpful in understanding the pathogenesis of depression. Therefore, a rapid and sensitive underivatized liquid chromatography-tandem mass spectrometry method was developed and validated for the simultaneous monitoring of the levels of ten neurotransmitters and their metabolites in rat serum and limbic system and successfully applied to quantify the changes of neurotransmitter levels in chronic unpredictable mild stress-induced rats. The analytes studied were mainly involved in tyrosine metabolism, tryptophan metabolism, and glutamate cycling pathways, which are important in the pathogenesis of depression. It had been verified the method was sensitive and effective, with satisfactory linearity, and met the requirements of biological sample determination. Levels of neurotransmitters in rat serum, hippocampus, amygdala, prefrontal cortex, striatum, and hypothalamus were determined via the method. The results showed serotonin, dopamine, norepinephrine, and their metabolites were decreased, glutamine was increased, and glutamate was disturbed in chronic unpredictable mild stress-induced depression rats. This method provides a new approach to studying the pathogenesis of depression and other neurological disorders.