• Proceedings of the KSME Conference
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• 2008.11a
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• pp.110-114
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• 2008

Determination of weld-induced residual stress has been an important issue in nuclear power industry because several failures were reported in dissimilar metal weld parts due to primary water stress corrosion cracking. In this context, a couple of remarkable round robin analyses were conducted to quantify the welding simulation variables and to establish optimized numerical analysis process. The purpose of the present research is to introduce welding simulation results for a safety and relief nozzle, which has a dissimilar metal weld part as well as a similar metal weld part. First, finite element analyses are carried out to calculate residual stresses at the inside of nozzle considering only dissimilar metal welding. Subsequently, residual stresses taking into account both the dissimilar and similar metal welding are computed. The similar metal weld effect is evaluated by compa

• Proceedings of the Korean Society for Technology of Plasticity Conference
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• 2005.10a
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• pp.418-422
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• 2005

In this study, the die design and die series on the surface residual stress of cold drawn eutectoid steel wire has been investigated. Test pieces were fabricated using die series with different mean and final reduction ratio. Surface residual stresses in the axial direction were measured by X-ray diffraction, Broker's 2-dimensional GADDS system. Results were compared with stress profiles which were calculated by 3D and 2D finite element simulation, Hibbitt's ABAQUS 6.4 program in Finite Element Analysis. By means of FEA method, optimal die shape considering delta-parameter were induced and applied in order to determine die sequence designs. Balance of the drawing stresses was also introduced to optimize die sequence.

• Transactions of Materials Processing
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• v.15 no.2 s.83
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• pp.153-157
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• 2006

In this study, the die design and die series on the surface residual stress of cold drawn eutectoid steel wire have been investigated. Test pieces were fabricated using die series with different mean and final reduction ratios. Surface residual stresses in the axial direction were measured by X-ray diffraction, Bruker's 2-dimensional GADDS system. The results were compared with stress profiles that were calculated by 3D and 2D finite element simulations, ABAQUS 6.4 program in finite element analysis(FEA). By means of the FEA method, optimal die shape considering delta-parameter were induced and applied in order to determine die sequence designs. Balance of the drawing stresses was also introduced to optimize die sequence.

• The Journal of Korean Academy of Prosthodontics
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• v.29 no.1
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• pp.1-11
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• 1991

A two dimensional finite element method was used to analyze the changes in mechanical behavior of the supporting structures when a fixed prosthesis replaced a mandibular 1st molar. In the unrestored situation as the degree of bone resorption increased, there was a corresponding increase in stress in the periodontium. Tilting of the molar abutment induced the additional stress on the mesial side of the root. The presence of a fixed prosthesis markedly reduced the magnitude and distribution of stress in the periodontium. The mechanical advantage obtained by a fixed prosthesis was greater in the situation of a tilted 2nd molar with reduced bone support than with the higher bone levels.

• Journal of Welding and Joining
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• v.22 no.3
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• pp.45-49
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• 2004

Generally, it is used the compensation spring to compensate the inaccuracy of screen image induced by thermal deformation in CRT monitor. Its mechanism is hi-metallic system made of heterogeneous metals and these springs are bonded by laser welding. But laser welding induces a non-uniform temperature distribution, and residual stress is yielded locally by these temperature deviation. Therefore, this study measures the curvature constant to assess functions of the compensation spring of shadow mask with respect to increment temperature and estimates the effect of residual stress on the performance of tri-metal used to compensation spring.

• Current Optics and Photonics
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• v.3 no.6
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• pp.502-509
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• 2019

Based on the typical pixel structure and parameters of a polysilicon uncooled bolometer, the absorption rate of a polysilicon microbridge infrared detector for 10.6 ㎛ laser energy was calculated through the optical admittance method, and the thermal coupling model of a polysilicon microbridge component irradiated by far infrared laser was established based on theoretical formulas. Then a numerical simulation study was carried out by means of finite element analysis for the actual working environment. It was found that the maximum temperature and maximum stress of the microbridge component are approximately exponentially changing with the laser power of the irradiation respectively and that they increase monotonically. The highest temperature zone of the model is gradually spread by the two corners of the bridge surface that are not connected to the bridge legs, and the maximum stress acts on both sides of the junction of the microbridge legs and the substrate. The mechanism of laser-induced hard damage to polysilicon detectors is the melting damage caused by high temperature. This paper lays the foundation for the subsequent study of the interference mechanism of the laser on working state polysilicon detectors.

• Preventive Nutrition and Food Science
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• v.16 no.3
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• pp.224-229
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• 2011

The radical scavenging activity and inhibition effect from lipid peroxidation induced by peroxyl radical of methanol extract from Perilla frutescens and its active compound, rosmarinic acid (RA), were investigated in vitro. The treatment of extract and RA scavenged 1,1-diphenyl-2-picrylhydrazyl, hydroxyl radical (${\cdot}OH$) and nitric oxide in a concentration-dependent manner. In particular, the extract and RA showed strong radical scavenging activity against ${\cdot}OH$, the most toxic and reactive radical. In addition, Perilla frutescens and RA effectively inhibited lipid oxidation induced by sodium nitroprusside and 2,2'-azobis(2-aminopropane) dihydrochloride, determined by the ferric thiocyanate method. The present results suggest that Perilla frutescens and RA play a protective role against oxidative stress induced by free radical and lipid peroxidation.

• Environmental Analysis Health and Toxicology
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• v.27
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• pp.11.1-11.8
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• 2012

Objectives: Hepatotoxicity of acetaminophen has been widely studied. However, the adverse effects on the heart have not been sufficiently evaluated. This study was performed to investigate cytotoxicity and alterations of gene expression in cultured cardiomyocytes ($H_9C_2$ cells) after exposure to acetaminophen. Methods: $H_9C_2$ cells were incubated in a 10 mM concentration of acetaminophen for the designated times (6, 12, and 24 hours), and cytotoxicity was determined by the 3-(4, 5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide method. Alteration of gene expression was observed by microarray analysis, and RT-PCR was performed for the three representative oxidative stress-related genes at 24 hours after treatment. Results: It revealed that acetaminophen was toxic to cardiomyocytes, and numerous critical genes were affected. Induced genes included those associated with oxidative stress, DNA damage, and apoptosis. Repressed genes included those associated with cell proliferation, myocardial contraction, and cell shape control. Conclusions: These findings provide the evidences of acetaminophen-induced cytotoxicity and changes in gene expression in cultured cardiomyocytes of $H_9C_2$ cells.

• Biomedical Science Letters
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• v.12 no.4
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• pp.435-438
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• 2006

In eukaryotes, ER stress induces UPR (unfolded protein response) via IRE1 activation which sends a molecular signal for XBP1 mRNA splicing in the cytosol. During this mRNA splicing, 23 nt removed in which contains PstI site and then resulting XBP1 product is not digested with PstI restriction enzyme. In this study, using this XBP1 mRNA splicing mechanism, the effect of heat shock on thyrocytes is studied, because heat shock response in the thyrocytes needs more study to understand thyroid physiology under alternative environments. ER inducible drugs (tunicamycin, DTT, $Ca^{2+}$ ionopore A23187, BFA) induce ER stress in the thyrocytes. From 3 hours after heat shock, ER stress is induced and which is reversible when heat shock is without. While $Ca^{2+}$ ionopore A23187 is reversible from ER stress by washing out the drug, thapsigagin is irreversible. Other ER inducible drugs are not so sensitive to ER stress repairing. XBP1 mRNA splicing in a cell is very available method to detect ER stress. It needs only a small quantity of total RNA and processing also very easy.

• Journal of the Korean Ceramic Society
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• v.25 no.4
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• pp.364-372
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• 1988

The mechanical properties and microstructure of ceramics of the system Al2O3-ZrO2-Y2O3 sintered at 1$650^{\circ}C$ for 2h after powder preparation by the precipitation method from Al2(SO4)3.18H2O, ZrOCl2.8H2O and YCl3.6H2O were investigated. The Al2O3-ZrO2-Y2O3 ceramics sintered at 1$650^{\circ}C$ for 2h after mixing alpha-Al2O3 and ZrO2-Y2O3 powders, both were separately precipitated and calcined, were found to have the relative density higher than 97.5% so that the strengthening and toughening mechanisms could be explained mainly as the stress-induced phase transformation. On the other hand, the sintered bodies prepared by co-precipitating the three starting materials were measured to have the relative density lower than 85% so that the degradation of strength were observed above 15 vol% ZrO2 contents due to the high porosity by which the effect of stress-induced phase transformation was assumed to be depressed.