• Title/Summary/Keyword: stress gene

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Thioredoxin System and Redox Signaling; Defence against Stress and Toxicity

  • Yodoi, Junji;Masutani, Hiroshi;Nakamura, Hajime
    • Proceedings of the Korean Society of Toxicology Conference
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    • 2001.05a
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    • pp.84-88
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    • 2001
  • Human Thioredoxin (TRX) with with redox-active dithiol (C-C-Y-C-) in the active site has been cloned as adult T cell leukemia derived factor produced by HTLV-I transformed cells. Thioredoxin (TRX) is one of the major components of the thiol-reducing system and plays multiple roles in cellular processes such as proliferation, apoptosis and gene expression.(omitted)

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