Kim, Dae-Won;Yang, Joshua SungWoo;Kim, Pan-Jun;Chu, In-Sun;Jeong, Ha-Woong;Park, Hong-Seog
Proceedings of the Korean Society for Bioinformatics Conference
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2005.09a
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pp.361-365
/
2005
Over the past few years, the complex and subtle roles of microRNA (miRNA) in gene regulation have been increasingly appreciated. Computational approaches have played one of important roles in identifying miRNAs from plant and animals, as well as in predicting their putative gene target. We present a new approach of comprehensive analysis of the evolutionarily conserved element scores and applied data compression technique to detect putative miRNA genes. We used the evolutionarily conserved elements [19] (see more detail on method and material) to calculate for base-by-base along the candidate pre-miRNA gene region by detecting common conserved pattern from target sequence. We applied the data compression technique [20] to detect unknown miRNA genes. This zipping method devises, without loss of generality with respect to the nature of the character strings, a method to measure the similarity between the strings under consideration [20]. Our experience to using our new computational method for detecting miRNA gene identification (or miRNA gene prediction) has been stratified and we were able to find 28 putative miRNA genes.
Purpose: To evaluate the current status of utilization and implementation of health promotion programs for Korean middle-aged women in public health centers. Methods: Three-phase stratified sampling was done to select 1304 middle-aged women (aged 40-64 years) from all regions of Korea. The data were collected by face-to-face interviews using a structured questionnaire for individual responses and mailed surveys to 126 public health centers. Descriptive statistics and $x^2$-test were done for data analysis. Results: Only 12 of the 126 public health centers (9.9%) implemented health promotion programs for middle-aged women, with the lack of manpower being cited as the main reason for the absence of programs. From individual responses, 11.3% had participated in health promotion programs offered by public health centers. The main reasons for not participating were inconvenient times and lack of information. Significant differences were found in the frequency of participation in programs, exercise programs and diabetes management according to the size of region. The majority of the respondents cited the need for medical services, followed by programs focused on stroke prevention and leisure time management. The responses on the willingness to participate followed a similar pattern. Conclusion: There are gaps between the utilization of health promotion programs by middle-aged women and what is offered by public health centers. The results of this study support the need to develop more health promotion programs focusing specifically on the needs of middle-aged women.
Background: Only few epidemiological data on primary central nervous system (CNS) tumors in Shanghai have been reported. Methods: All cases of primary CNS tumors that were registered at Center for Disease Control and Prevention (CDC) were collected (1973-2007: urban Shanghai; 2003-2007: whole Shanghai city). Trends were analyzed using joinpoint analysis and rates were stratified by age, gender and region. Histological data were collected from both CDC and Huashan Hospital. Results: From 1973 to 2007, the five-year average incidence rate in urban Shanghai increased in both genders, especially in the elderly population. Joinpoint analysis showed the age-adjusted incidence rate for males increased first but then plateaued, whilst rates for females continued increasing over the 35 years. For the five-year status quo (2003-2007), rural had a higher age-adjusted incidence rate than urban populations, and females higher than males, especially those with advanced age. According to CDC (2003-2007) and Huashan Hospital (1951-2011), the two most common histological subtypes were neuroepithelial tumors (with male predominance) and meningiomas (with female predominance). Conclusions: In Shanghai, a steadily increased incidence rate of primary CNS tumors was observed in general, and in the elderly and female population in particular.
Fossil power plants firing lower grade coals or equipped with modified system for NOx controls are challenged with maintaining good combustion conditions while maximizing generation and minimizing emissions. In many cases significant derate, availability losses and increase in unburned carbon levels can be attributed to poor combustion conditions as a result of poorly controlled local fuel and air distribution within the boiler furnace. In order to develop a on-line combustion tuning system, field test was conducted at operating power boiler. During the field test the exhaust gases' $O_2$, NOx and CO was monitored by using a spatially distributed monitoring grid located in the boiler's high temperature vestibule and upper convective back-pass region. At these locations, the flue gas flow is still significantly stratified, and air in-leakage is minimal which enables tracing of poor combustion zones to specific burners and over-fire air ports. using these monitored information we can improving combustion at every point within the furnace, therefore the boiler can operate at reduced excess $O_2$ and gas temperature deviation, reduced furnace exit gas temperature levels while also reducing localized hot spots, corrosive gas conditions, slag or clinker formation and UBC. Benefits include improving efficiency, reducing NOx emissions, increasing output and maximizing availability. Discussion concerning the reduction of greenhouse gases is prevalent in the world. When taking a practical approach to addressing this problem, the best way and short-term solution to reduce greenhouse gases on coal-fired power plants is to improve efficiency. From this point of view the real time optimized combustion tuning approach is the most effective and implemented with minimal cost.
Regarding leisure and work as very important in residential life of old ages, this study analyzed their preference by leisure and work for senior congregate housing, which can provide proper work and leisure activities for older people who are able to manage their social activities with healthy condition. It conducted a survey of middle aged of the 50's who would face problems of senior housing in 2010, with stratified sampling by region, sex and housing structure type. Totally 556 Questionnaires were used for the final analysis. The research results showed that, first, the group which was positive toward their works mostly had spouse of the age of early 50' s and work for professional, technological, managerial positions with good health. Second, the more positive group towards their work showed high willingness to move in senior congregate housing, than a negative group towards their work, and put a weight on the openness of shared space and facilities as well as various alarming equipments, common space, common programs and the ability of managers. Third, according to the attitudes toward leisure activities, there were differences in each group by housing structure type, education of their own or their spouses, monthly income, property, economic ability, health condition, living together with spouse, housing tenureship, and usable area of houses. The fourth was that those who enjoy active leisure activities presented high willingness to move in senior congregate housing than those of negative attitude and also there was a difference in managerial ways. Throughout the results of the study, it appeared that a group of positive attitude toward work and leisure, than that of negative attitude, recognized the importance of senior congregate housing which social and leisure programs could support. It implied necessary to develop housing for the older people who have enough ability to manage their leisure activity as well as their work. The study is likely to have a contribution to suggest practical data for helping the development of housing for self-reliant seniors by analyzing their preference on senior congregate housing by their attitudes toward work. The research for the factors of various designs and managements by leisure and work may become the following research theme of the study.
Although the proportion of frail elderly among the elderly population has been rapidly increasing, there is little preparation to provide housing alternatives for them in Korean society. Long-term care facility a housing alternative for frail elderly that enables them to receive social and medical care services that enhance the quality of their life. This research was conducted to study the opinions of middle-aged Koreans about long-term care facilities for the frail elderly. This study provides useful suggestions for the development of user-paid long-term care facilities in the near future. A survey questionnaire was administered to 600 adults in their 50s to collect data. The sample was stratified according to region, gender, and housing structure type. The results showed that most of the respondents were aware of long-term care facilities for the frail elderly; but they were relatively unwilling to live in these facilities, as compared to other housing alternatives. However, a larger number of respondents said that as they became very frail, they would be willing to live in these facilities. The respondents expressed a high level of need for user-paid long-term care facilities as an alternative to hospitalization. Also, they wanted to have a variety of long-term care facilities that are designed for different levels of disability. The education level of respondents and their spouses, average monthly income, subjective economic level, and religion were major variables that differentiated significantly the opinions about long-term care facilities for the frail elderly.
Journal of the korean academy of Pediatric Dentistry
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v.41
no.1
/
pp.34-39
/
2014
Nevoid basal cell carcinoma syndrome(NBCCS) is a autosomal dominant disorder, and its major manifestations are multiple basal cell carcinoma, keratocystic odontogenic tumor, rib anomalies, palmer and plantar pits, calcification of the falx cerebri. Keratocystic odontogenic tumor(KCOT) is defined as intraosseous tumor of odontogenic origin with a characteristic lining of parakeratinized stratified squamous epithelium and potential aggressive behavior. We report a case of a 3-year-old patient with nevoid basal cell carcinoma syndrome who initially presented with unilocular keratocystic odontogenic tumor in maxillary canine region. Keratocystic odontogenic tumor was treated by enucleation, and periodic follow-up check will be required for early diagnosis of additional diseases related with this syndrome.
Fossil power plants firing lower grade coals or equipped with modified system for $NO_x$ controls are challenged with maintaining good combustion conditions while maximizing generation and minimizing emissions. In many cases significant derate, availability losses and increase in unburned carbon levels can be attributed to poor combustion conditions as a result of poorly controlled local fuel and air distribution within the boiler furnace. In order to develop a on-line combustion tuning system, field test was conducted at operating power boiler. During the field test the exhaust gases' $O_2,\;NO_x$ and CO was monitored by using a spatially distributed monitoring grid located in the boiler's high temperature vestibule and upper convective rear pass region. At these locations, the flue gas flow is still significantly stratified, and air in-leakage is minimal which enables tracing of poor combustion zones to specific burners and over-fire air ports. using these monitored information we can improving combustion at every point within the furnace, therefore the boiler can operate at reduced excess $O_2$ and gas temperature deviation, reduced furnace exit gas temperature levels while also reducing localized hot spots, corrosive gas conditions, slag or clinker formation and UBC. Benefits include improving efficiency, reducing $NO_x$ emissions, increasing output and maximizing availability. Discussion concerning the reduction of greenhouse gases is prevalent in the world. When taking a practical approach to addressing this problem, the best way and short-term solution to reduce greenhouse gases on coal-fired power plants is to improve efficiency. From this point of view the real time optimized combustion tuning approach is the most effective and implemented with minimal cost.
Park, J.S.;Ha, D.H.;Yeum, J.K.;Ha, J.Y.;Chung, S.S.
Journal of Power System Engineering
/
v.12
no.4
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pp.5-11
/
2008
The RI gasoline engine haying a sub-chamber had a high cycle variation due to the difficulty of the residual gas scavenge in the sub-chamber. To solve this problem and improve the combustion performance of RI engine, we devised a method to inject directly CNG fuel into the sub-chamber. A DI diesel engine of single cylinder was converted into a RI-CNG engine and an electronic control unit for the engine was manufactured. In this study, the combustion characteristics of the RI-CNG engine were investigated with the injection timings and air excess ratios at the load conditions of 50% throttle open rate and 1700rpm. As the results from this study, the RI-CNG engine worked reliably under the condition of the ignitable lean limit of $\lambda=1.7$ by showing the $COV_{imep}$ below about 5%. And the highest thermal efficiency could be obtained in the injection timing that produced the high imep and the low $COV_{imep}$ at the same time. The CO emission concentration indicated very low values and the THC and $NO_x$ showed an opposite pattern. With a view to improving the thermal efficiency and reducing the harmful emissions, the proper control region of the ignition timing and the mixture ratio were nearly ATDC $20^{\circ}\sim50^{\circ}$ and $\lambda=1.4$ respectively.
The mission of the Forest Inventory and Analyis (FIA) program of the Forest Service, U.S. Department of Agriculture, is to conduct the national forest inventory of the United States of America for purposes of estimating the area of forest land; the volume, growth, and removal of forest resources; and the health of the forest. Users of FIA data, estimates, and related products include land managers, policy and decision-makers, forest industry, environmental organizations, and university researchers. To accomplish its mission, the FIA program has established a sampling design with an intensity of approximately one permanent plot per 2,400 ha across the entire country. Depending on the region of the country, each plot is remeasured at intervals of five or 10 years. The program releases data annually and reports estimates at the county level for each state every five years. Due to budgetary constraints and natural variability among plot observations, sufficient numbers of plots cannot be measured to satisfy precision guidelines for the estimates of many variables unless the estimation process is enhanced using ancillary data. Classified satellite imagery has been demonstrated to be a source of ancillary data that can be used with stratified estimation techniques to increase the precision of estimates with little corresponding increase in costs. A crucial factor restricting the utility of FIA data is that the exact locations of inventory plots cannot be released to the public. Thus, users are generally not able to obtain estimates for small areas or for their own areas of interest if exact plot locations are required. To compensate, satellite imagery, inventory plot data, and the k-Nearest Neighbors technique are being used to construct Internet-based maps of forest attributes from which estimates for arbitrary user-defined areas of interest may be obtained.
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