• 대한의용생체공학회:학술대회논문집
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• 대한의용생체공학회 1997년도 추계학술대회
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• pp.9-13
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• 1997

The present study was designed to develop the functional electrical stimulation system in order to restore motor function of paralytic patients. We attempt to establish adequate stimulus parameters for the recovery of work unction in lower limb paralysis patients and to develop the electrical stimulation system, which is effective to protect foot drop in these patients. In our animal and human experiment, adequate stimulus condition for surface electrode on the lower limb were 0.2-0.3ms at the duration and 50 Hz, which contain 600Hz train pulse. This parameter has efficiently prevented the foot drop from lower limb paralysis, decreased muscle fatigue and induced powerful contraction of lower limb muscle.

• 대한의용생체공학회:의공학회지
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• 제23권4호
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• pp.287-293
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• 2002

시변 자계를 이용하여 비접촉적인 방법으로 신경을 자극하기 위해서는 신경자극코일에 대용량 전류 펄스를 순시적으로 인가해야만 한다. 신경자극코일에 인가하는 전류 펄스의 주파수를 증가할수록 신경자극코일에 전력을 공급하는 전력공급기의 용량이 커지게 되고 신경자극코일에 발생하는 열량도 커지는 문제가 발생한다. 본 논문에서는 이러한 문제를 완화하기 위해 새로운 형태의 신경자극코일을 제안하였다. 신경자극코일에 강자성체 구조물을 부착하여 자계 거울 효과를 내게 하면 신경자극코일의 효율이 증가하게 된다. 다양한 형태의 신경자극코일에 대해 자계 거울 효과를 유한요소법으로 분석하였고 몇 종류의 신경자극코일에 대해 실험한 결과를 제시하였다.

• The Journal of Korean Physical Therapy
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• 제12권1호
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• pp.119-127
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• 2000

In this case report we demonstrated the improvemen of gait pattern and the facilitation of postwalk locomotion on the child who has severe mental retardation with Incomplete gait pattern. Treatments included to stimulate vestibular using balance board and vestibular stimulator, to train weight hearing and shifting, to facilitate visual perception motor coordination, and to train walk ann postwalk locomotion in environment similar to actual daily life. It was performed 130 sessions for 10 months. With this treatment, she could accomplished dynamic stability so that she didn't fall at walk after $1\~2$ months of treatment, and could have done climbing up and down without hand support after 10 months. In gross motor function measure(GMFM), total motor function was improved to $89.98\%$ from $73.53\%$.

• 한국미생물·생명공학회지
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• 제42권3호
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• pp.312-315
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• 2014

인체 면역증강제로 활용 가능성을 조사하기 위해 R. aquatilis AY2000 균이 생산하는 당단백질인 AYS의 면역세포에 대한 독성과 면역증강 효과를 조사하였다. 그 결과 AYS는 적혈구에 대한 용혈작용과 hPBMC에 대한 증식 또는 사멸효과는 나타내지 않았으나, 배양 중인 hPBMC를 응집시키는 효과를 나타내었다. 또한 AYS는 in vitro에서 hPBMC에 작용하여 염증성 cytokine인 IL-6, IFN-${\gamma}$, TNF-${\alpha}$와 IL-5 생성을 유도하였고, 생쥐에서 AYS는 alum에 비해 항-BSA의 생산력을 더욱 증가시켰다.

• 농업과학연구
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• 제40권1호
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• pp.13-18
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• 2013

Effect of electric pulse stimulation was tested on the fruit body formation of valuable mushroom Tricholoma matsutake in the field of natural habitat of this mushroom. After applying the electric stimulator to the specific area of pine forest we found that the treatment especially stimulated the fructification of T. matsutake. And the most valuable findings of our study was that only our treatment plots showed fruit body formation whereas the control plots and the whole natural habitats of our study area showed zero production of this mushroom during the same time. From the point of view of mushroom production, our experiment shows that fruit body production can be upgraded by using pulsed power as an electrical stimulation in the field of the natural habitat of this mushroom. These findings from our experiment confirm the effectiveness of the significance of pulsed power technology for the improvement of T. matsutake fruit body production in the natural habit of this mushroom.

• Perspectives in Nursing Science
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• 제9권2호
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• pp.111-118
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• 2012

Purpose: This study investigated the effects of simulation-based nursing education (for the care of congestive heart failure patients) on self-directed learning competency, clinical knowledge and problem-solving ability among nursing students. Methods: A one-group, pre-post design was utilized with 87 nursing students as the subjects. The scenario of simulation-based nursing education was created using a high-fidelity patient stimulator, and consisted of four states ((1) assessment, (2) reviewing laboratory data and administering medications and treatments, (3) managing increased dyspnea and decreased urine output, and (4) handling the "getting better" state). The simulation-based nursing education included orientation, team-based learning, team-based practice, and debriefing. The data were analyzed using descriptive statistics, Pearson's correlation coefficients and paired t-tests. Results: The scores on the factors for self-directed learning competency (t=-2.57, p= .011), clinical knowledge (t=-6.85, p<.001), and problem-solving ability (t=-3.01, p= .003) increased significantly after the education intervention. Conclusion: Simulation-based nursing education is useful in improving self-directed learning competency, clinical knowledge, and problem-solving ability in nursing students.

• 대한전자공학회논문지
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• 제15권5호
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• pp.19-24
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• 1978

기계적 진동 주파수와 파형, 2점식별 thresho1d 치, 접촉자의 크기에 대한 피체 진동촉각의 기능적 성질을 심리물리실험에 의해 연구했다. 이의 실험 결과를 기초로 하여 압전 진동소자를 이용한 진동촉각 자극장치를 제작하여 한글을 인식하기 위한 맹인용 시각보조 장치로써 제안했다. 촉각출력상은 200 Hz의 구형파에 의해 진동하는 8열×l행의 소형 진동자열에 의해 집게 손가락에 표시했다. NOVA미니컴퓨터의 제어에 의해 한글 자모 24자중 하나를 택하여 진동자열의 8점에 왼쪽에서 오른쪽으로 제시하도록 했다. 한글 식별률실험은 설계한 실험시스템에 의해 학습효과없이 행했으며 측정된 평균식별률은 90%였다.

• 대한조선학회논문집
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• 제55권3호
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• pp.265-273
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• 2018

Direct numerical and large eddy simulations of transitional flows around studs installed on flat plate and bulbous bow have been performed to investigate an effectiveness of turbulence stimulators on laminar-to-turbulence transition at a very low speed. The flow velocity was determined to be 0.366m/s corresponding to 4 knots of full-scale ship speed when the objective ship was Kriso container ship. The spatial evolution of skin friction coefficient disclosed that a fully development of turbulence was observed behind the second stud installed on flat plate while a rapid transition from laminar to turbulence gave rise to the fully development of turbulence behind the first stud installed on bulbous bow. A comparison of streamwise mean velocity profiles showed that the viscous sublayer and log-layer were in good agreement with previous results although the friction velocity of Smagrosinsky sub-grid scale model was about 10% larger than that of direct numerical simulation. While the turbulence intensities of bulbous bow was similar to those of flat plate in inner region, larger intensities of turbulence were observed in outer region of bulbous bow than those of flat plate.

• 약학회지
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• 제47권6호
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• pp.422-431
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• 2003

The use of recombinant human erythropoietin (rhEPO), a stimulator of erythropoiesis, banned in sports because of the medical risk associated with thrombosis. Due to analytical difficulties to differentiate between natural human EPO (hEPO) and rhEPO, blood parameters of erythropoiesis such as contents of hemoglobin (cut-off value <17.5 g/d l for man, and < 16.0 g/dl for women), hematocrit and reticulocytes (cut-off value <2.0%) were measured to focus the misuse of rhEPO. We conducted anti-doping test for 122 blood samples of the World Cup athletes. The mean values of key parameters are as follows; 14.5$\pm$1.0 g/dl for hemoglobin, 41.7$\pm$2.8% for hematocrit, and 1.3$\pm$0.4% for reticulocyte. Blood sample was found to be stable up to 8 hours for the reticulocyte measurement. In addition, the soluble transferrin receptor and ferritin levels were measured by immunoassay methods using plasma samples (n=28) in which the mean value was 0.8$\pm$0.5 $\mu\textrm{g}$/$m\ell$ and 54.6$\pm$33.7 ng/$m\ell$, respectively. The results indicate that all samples tested were negative for the blood parameters of indirect anti-doping test for hEPO misuse. The statistical evaluation suggest that several other parameters such as red blood cell, mean corpuscular hemoglobin concentration, mean corpuscular volume, mean corpuscular hemoglobin and white blood cell could be considered as factors influencing hEPO function in addition to five parameters mentioned.

• The Korean Journal of Pain
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• 제20권2호
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• pp.186-189
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• 2007

The most important factors for successful stimulation of the spinal cord are strict patient selection and proper lead position. To ensure proper lead position, paresthesia produced by the stimulator should cover all of the areas in which pain is occurring. Until recently, only the quadripolar electrode lead has been used in for spinal cord stimulation in Korea, however, the 8 electrode lead was recently introduced to offer greater programming options and enhance the precision with which paresthesias is delivered to the desired sites. In addition, because the 8-electrode lead has a longer electrode span, it provides greater dermatomal coverage of up to 2 vertebral segments. Furthermore, the 8-electrode lead allows electronic repositioning of the stimulation to accommodate changing pain patterns, thereby reducing the need for lead revisions due to lead migration. Here, we present a case in which complex regional pain syndrome type I was successfully managed using an 8-electrode lead to induce spinal cord stimulation.