• Proceedings of the PSK Conference
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• 2002.10a
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• pp.388.1-388.1
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• 2002

Aconiti Tuber (Aconitum spp. tuber, Ranunculaceae) which contains bioactive but toxic alkaloids has been used as analgesic. cardiotonic, diuretic. and stimulant. We have previously reported two new C-19 norditerpenoid alkaloids and five known norditerpenoid alkaloids. Further study has now led to the isolation of two new norditerpenoid alkaloids. 14-O-anisoylneoline and 14-O-veratroylneoline. (omitted)

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• v.1 no.1
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• pp.89-93
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• 1990

60 Attention-deficit hyperactive patients treated with stimulant drugs such as methylphenidate and pemoline were evaluated in regards to the therapeutic benefit and side effects of these drugs. The results were as follows : 1) Of the 60 subjects 34 showed considerable imporvement and only 8 showed little or no improvement. 2) Hyperactivity, inattention and impulsivity were improved markedly by stimulants These behavioral changes were accompanied by improved performance in classroom. 3) School age children tended to show more improvement than preschool children or adolescence. 4) Of the 60 subjects 25 showed no side effect and only 6 showed severe side effects, and common side effects were decreased appetite, insomnia and irritability or nervousness. It is the author's impression that despite of the therapeutic efficacy of these drugs when they were administered on a short-term basis, long-term outcome dose not seem to be altered by the administration of these agents.

• Journal of the Korea Fashion and Costume Design Association
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• v.18 no.2
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• pp.237-251
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• 2016

The purpose of this study is to provide the improvement idea for an school uniform styling that better satisfies female high school students' changing demands, through evaluating images differences according to design variation in school uniforms. This study was carried out with a between-subject design by using the stimulant materials of school uniform design and image assessment scale. The stimulant materials used for this study were 27 designs with blazer/skirt ensemble and 21 designs with vest/skirt ensemble. The survey materials were collected through a questionnaire from a total of 192 female high school students living in Gyeongsangnam-do. As a result of analyses on a image of blazer/skirt ensembles, 4 factors were extracted such as neatness, uniqueness, activeness, and attractiveness. Blazer was the only variables that exerted significant effects on neatness, uniqueness, and attractiveness. As a result of analyses on a image of vest/skirt ensembles, 4 factors were extracted such as attractiveness, neatness, uniqueness, and activeness. Skirt was the only variables that exerted significant effects on attractiveness, neatness, and uniqueness. Neat image was perceived to be high in ensembles of standard blazer/standard collar/horizontal-seam skirt, standard vest/skirt with horizontal color combination, and buttons-down vest/horizontal-seam skirt. Unique image was perceived to be high in ensembles of blazer with bindings/standard collar/solid skirt, and vest with pockets/skirt with vertical bindings. Also, active image was perceived to be high in ensembles of vest with pockets/skirt with vertical bindings, and buttons-down vest/skirt with vertical bindings. Attractive image was perceived to be high in ensembles of blazer with bindings/peaked lapel/skirt with vertical bindings, and standard vest/horizontal-seam skirt. In conclusion, this study reveals that different items and pieces of school uniforms can be combined in many different ways to create quite diverse looks. Thus, this study provides important basic data for research on teenagers' fashion and clothing.

• Journal of the Korean Chemical Society
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• v.36 no.5
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• pp.764-769
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• 1992

Strigol, a natural product isolated from root exudates of cotton, was found to be an extremely potent seed germination stimulant for the parasitic plant, witchweed. Witchweed seeds can remain dormant in the soil for several years until favorable conditions prevail including exposure to some type of chemical germination stimulant. Several strigol analogues, 3-methyl-4-(2-oxo-3,3a,6,6a-tetrahydro-2H-cyclopenta[b]furan-3-ylidenemethoxy)-but-2-en-4-olide(21), 4-(2-oxo-3,3a,6,6a-tetrahydro-2H-cyclopenta[b]furan-3-ylidenemethoxy)but-2-en-4-oilde(22), 3-methyl-4-(2-oxotetrahydrofuran-3-ylidenemethoxy)-but-2-en-4-olide(23), and 4-(2-oxotetrahydrofuran-3-ylidenemethoxy)-but-2-en-4-olide(24), were synthesized.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• v.14 no.1
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• pp.36-52
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• 2003

Attention deficit/hyperactivity disorder is one of the most comminly treated conditions in the child psychiatric units and results in substantial impairment in peer, family and academoc functioning. For 70% to 80% of children with a diagnosis of ADHD, stimulant tratment results in successful improvement of the core ADHD symptoms. However, children with ADHD have high level of comorbidity and may respond differently from children with ADHD without comorbidity. Therefore they may need specific treatment plan. We reviewed efficacy and safety of prescribed medication for treating children with ADHD, the relationship between ADHD and the comorbid conditions and treatment algorithm projects of ADHD with/without comorbid conditions performed Korean and American child psychiatrists. Our main objective is to increase the uniformity of treatment and improve the clinical outcomes of children with comorbid ADHD.

• Journal of the Korean Society of School Health
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• v.4 no.1
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• pp.88-99
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• 1991

The purpose of this study was attempted to analyze the relationship between drug abuse and the other problem behavior Patterns among high school students in Cheju. In order to achieve these set-goals, questionaires were finally supplied to the total 379 case of 9 high school from October to December, 1990. The collected data were processed using the SPSS-X computer program and statistically analyzed by the Chi-square method and. percentage. Results of the study were as follows: Among the 370 adolescents, 32.4% of students experienced cigarette smoking in their life, adolescents who experienced alcohol drinking were 46.8%, 0.5% of the students ever used marihuana; cocaine 0.3%, stimulant 3.2%, hallucinogen and inhalants 0.5%, tranquilizer 1.4%, analgesics 31:6%, antitussives 6.5%, antihistamines 1.9%. And all students never experienced the amphetamines and narcotics. The rates of drug use except stimulant and antitussive were higher in the male than in the female students. For the analysis of personal identifying datum, the rates of experienced smokers increased among groups of buddhist and the rates of experienced alconoi drinking increased among groups of no religion. Drug abuser increased among the group lower socio-economic status student, the adolescents whose parents have traditional education point of view. And it was also higher in those who were living only one than in those who were living together. Most students tended to use drugs after 17 or 18 years old. Drug users were more inclined to commit other problem behaviors when compared non-drug users. In the conclusion of the above results, it will be necessary to investigate the drug problem of adolescent. Drug abuse of students must be seen in an environmental context including family, school, peer group and society and not solely as the characteristics of an individual adolescent. And their parents and teachers must be on the alert for the behavior changes of their children such as changes of school performance, neglecting homework, tardiness or truancy from school, runaway from home, and mingled with bad companions, etc. We must recognize that drug abuse is frequently symptomatic of problems in the adolescent's environment.

• Journal of Aquaculture
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• v.20 no.1
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• pp.19-25
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• 2007

For establishing a basal diet for the Pacific bluefin tuna Thunnus orientalis (PBT), feeding stimulants were initially identified by omission test using the synthetic extract of horse mackerel, Trachurus japonicus. Four feeding trials were conducted using juvenile PBT weighing $9.0{\pm}0.91\;g$ (trial 1, 2 and 3) and $1.6{\pm}0.23\;g$ (trial 4), which were originated from an artificial seedling production. The fish fed the casein diet with each test solution were added at the ratio of 100 g casein diet to 100 g jack mackerel muscle. A complete synthetic extract of jack mackerel containing all 3 fractions, amino acid, nucleotide and organic nitrogenous base, exhibited a comparable feeding stimulant activity compared to that of natural extract. The omission of nucleotide or amino acid fraction showed lower feeding activity, but the omission of other nitrogenous fraction maintained a similar feeding stimulant activity compared to that of the synthetic extract (trial 1). Inosine-5' monophosphate $Na_2$ (IMP) was identified as a major constituent for maintaining feeding activity. The mixture of L-alanine, L-glutamic acid, L-histidine, L-lysine, taurine and IMP induced a similar feeding activity compared to that of the synthetic extract (trial 2 and 3). In trial 4, the highest feeding activity was finally obtained in the mixture of L-histidine, L-glutamine and IMP, followed by the synthetic extract, the mixture of L-lysine, L-alanine and IMP, IMP and the mixture of L-histidine, L-glutamic acid, L-lysine and L-alanine. These results revealed that the mixture of L-histidine, L-glutamic acid and IMP for the proper feeding stimulant of PBT in this study.

• YAKHAK HOEJI
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• v.17 no.1
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• pp.1-8
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• 1973

The pharmacological activities of paeoniflorin abtained from paeony roots, F$_M$100 from glycyrrhiza roots, crude saikosides from bupleurum roots, crude platycodin from platycodon roots, and bothj of ginsenoside Rb and ginsenoside Rg series from ginseng roots were investigated. Paeoniflorin, F$_M$ 100, crude saikosides, and crude platycodin exhibited sedative antipyretic, anlagesic and anti-ulcerative actions. In addition, crude saidosides and crude platycodin showed antitusaive and the potent anti-inflammatory action. An expectorant action was also observed with crude platycodin. These results coincided with the clinical applications of the aforementioned oriental medicinals. It also should be noted that crude saikosides nad crude platycodin are preferable to the other steroidal nad nonsteroidal drugs as an anti-inflammatory agent, because the drugs aggravate the digestive ulcer. In ginseng, G No3. and GNS frctions out of ginsenoside Rb series hsowed stimulant and antifatigue actions. The synergistic effects identified between paeoniflorin and F$_M$ 100 on the various pharmacological activities, have verified the reasonability of combined uses of two oriental drugs as Jakyak Gaqmcho-Tang.

• Journal of Veterinary Clinics
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• v.16 no.1
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• pp.100-107
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• 1999

Apoptosis is now widely recognized as a common form of cell death and represents mechanism of cell clearance in many physiological situations where deletion of cells is required. In vivo administration of bacterial lipopolysaccharide (LPS) to Balb/c mice induced DNA fragmentation in the thymus. DNA fragmentation in the thymus was roughly dependent on the dose of LPS injected and reached the peak 18 hours after injection. This apoptosis in the thymus might be mediated due to LPS stimulant. DEN (diethylnitrosamine) has been shown to cause liver cancer in experimental animals and humans. The hepatic tumorigenesis was induced by ad libitum feeding of DEN only. It was suggested that DEN induced hepatic tumorgenesis in rat is a good reproducible model for studying biochemical and pathophysiological changes associated with the development of hepatic tumorigenesis and apoptosis.

• Natural Product Sciences
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• v.17 no.1
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• pp.51-57
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• 2011

The seeds of Abrus precatorius L. (Family- Fabaceae) constitute the drugs Abrus, Gunja, or Ratti in commerce. In the Indian System of Medicine, the seeds are used for sciatica, paralysis, headache, dysentery, diarrhoea, leprosy, ulcer, nervous disorders, alopecia, as well as anti-inflammatory, antidiabetic, antibacterial, antitumor, sexual stimulant and abortifacient. Seeds are poisonous and therefore are used after mitigation. The protein abrin is responsible for the highly toxic properties of seeds. Quantitative HPTLC analysis of the methanolic extract of seeds determined the presence of 0.4018% gallic acid and 0.4009% glycyrrhizin. The present study was undertaken to develop an HPTLC method, as well as ascertain the physico-chemical, morphological and histological parameters to establish the authenticity of A. precatorius seeds.