• Title/Summary/Keyword: stibene derivative

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Leukotriene D4 Antagonistic Activity of a Stilbene Derivative Isolated from the Bark of Pinus Koraiensis

  • Song, Hong Keun;Jung, Jihyun;Park, Kwan Ha;Lim, Yoongho
    • Journal of Applied Biological Chemistry
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    • v.44 no.4
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    • pp.199-201
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    • 2001
  • A phenolic substance was isolated from the bark of Pinus koraiensis. It was identified to be pinostilbenoside. Its anti-$LTD_4$ activity was evaluated using isolated guinea pig trachea, and its half maximal bronchodilating activity ($EC_{50}$) was $593{\pm}56{\mu}g{\cdot}ml^{-1}$. Because it is not known that stilbene derivatives possess anti-asthmatic activity through $LTD_4$ antagonism, here we report the result.

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