• 제목/요약/키워드: stibene derivative

검색결과 1건 처리시간 0.015초

Leukotriene D4 Antagonistic Activity of a Stilbene Derivative Isolated from the Bark of Pinus Koraiensis

  • Song, Hong Keun;Jung, Jihyun;Park, Kwan Ha;Lim, Yoongho
    • Journal of Applied Biological Chemistry
    • /
    • 제44권4호
    • /
    • pp.199-201
    • /
    • 2001
  • A phenolic substance was isolated from the bark of Pinus koraiensis. It was identified to be pinostilbenoside. Its anti-$LTD_4$ activity was evaluated using isolated guinea pig trachea, and its half maximal bronchodilating activity ($EC_{50}$) was $593{\pm}56{\mu}g{\cdot}ml^{-1}$. Because it is not known that stilbene derivatives possess anti-asthmatic activity through $LTD_4$ antagonism, here we report the result.

  • PDF