• Title/Summary/Keyword: statistical variations

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The Generation of Typical Meteorological Year for Research of the Solar Energy on the Korean Peninsula (한반도 태양에너지 연구를 위한 일사량 자료의 TMY 구축)

  • Jee, Joon-Bum;Lee, Seung-Woo;Choi, Young-Jean;Lee, Kyu-Tae
    • New & Renewable Energy
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    • v.8 no.2
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    • pp.14-23
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    • 2012
  • The TMY (Typical Meteorological Year) for the solar energy study is generated using observation data with 22 solar sites from KMA (Korea Meteorological Administration) during 11 years (2000-2010). The meteorological data for calculation the TMY are used solar radiation, temperature, dew point temperature, wind speed and humidity data. And the TMY is calculated to apply the FS (Finkelstein and Schafer) statistics and RMSE (Root Mean Squared Error) methods. FS statistics performed with each point and each variable and then selected top five candidate TMM months with statistical analysis and normalization. Finally TMY is generated to select the highest TMM score with evaluation the average errors for the 22 whole points. The TMY data is represented average state and long time variations with 22 sites and meteorological data. When TMY validated with the 11-year daily solar radiation data, the correlation coefficient was about 0.40 and the highest value is 0.57 in April and the lowest value is 0.23 in May. Mean monthly solar radiation of TMY is 411.72 MJ which is 4 MJ higher than original data. Average correlation coefficient is 0.71, the lowest correlation is 0.43 in May and the highest correlation is 0.90 in January. Accumulated annual solar radiation by TMY have higher value in south coast and southwestern region and have relatively low in middle regions. And also, differences between TMY and 11-year mean of is distributed lower 100 MJ in Kyeongbuk, higher 200 MJ in Jeju and higher 125 MJ in Jeonbuk and Jeonnam, respectively.

Morphogenetical characteristics of Korean wild rat (Rattus norvegicus) (한국 야생 랫드의 형태 유전학적 특성)

  • Seong, Je-Kyung;Yun, Young-min;Park, Ji-young;Oh, Seung-hyun;Do, Seon-gil;Jin, Hee-kyung;Hyun, Byung-hwa;Suh, Jun-gyo;Oh, Yang-seok
    • Korean Journal of Veterinary Research
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    • v.39 no.5
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    • pp.896-907
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    • 1999
  • The morphometrical characteristics such as external measurements and mandible size assessment in mice and rats have to be highly heritable and sufficiently variable between strains in order to calculate a strain specific profiles. The coat color of Korean wild rats were observed and morphometric analysis of external measurements were carried out on Korean wild rats compared to laboratory strains in order to clarify the genetic characteristics of Korean wild rats and to establish background data as a domestication of Korean wild rats for new laboratory strain. Korean wild rats were captured from Chunchon and Hoengsong. 4 inbred and 1 outbred strains of rats were used in this study for the comparison of genetic characteristic of Korean wild rats. Total body length, head length, tail length, hind foot length and ear length were measured and then statistical analysis were carried out by discrimiant analysis. The coat color of Korean wild rat showed golden white in ventral portion and dark agouti in dorsal portion. Korean wild rats could be distinguished from the other laboratory strains distinctly by morphogenetical analysis. There was significant variations among Korean wild rat compared to those of the other laboratory strains of rat. This study may provide that Korean wild rats have a unique genetic characterization compared to those of other inbred strains of rats based on morphogenetical characteristics by external measurements.

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Evaluation of Trophic State of a Small-scale Pond (Wonheung) in Ecological Park (소규모 생태연못(원흥이 방죽)의 부영양화 평가)

  • Lee, Heung Soo;Chung, Se Woong;Choi, Jung Kyu;Shin, Sang Il
    • Journal of Korean Society on Water Environment
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    • v.24 no.6
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    • pp.741-749
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    • 2008
  • Many small-scale ponds that serve as ecological habitat, recreation and irrigation are faced to eutrophication problem, which causes aesthetic nuisance and ultimately loss of their functions. Thus accurate evaluation of the trophic state of these ponds is essential to provide rational information to the stakeholders so that they can develop effective management actions. In this study, the trophic state of a small pond (Wonheung) that experiencing water quality degradation due to vicinity land development was assessed using various Trophic State Indexes (TSIs) and statistical analysis including Principal Components Analysis (PCA) based on the field monitoring data obtained from May to December, 2007. The results showed that the pond is under eutrophic state with average total nitrogen (T-N) and total phosphorus (T-P) concentrations of $708.1{\mu}g/L$ and $59.3{\mu}g/L$, respectively. The factor loading plot obtained from PCA showed distinct two influencing factors, PC 1 and PC 2. PC 1 was grouped by T-P, Chlorophyll a (Chl-a), suspended solids (SS), TN/TP ratio, and transparency that all strongly related to the eutrophication state, while PC 2 by temperature, conductivity, dissolved oxygen (DO) and turbidity that explains the seasonal water quality variations. The limiting factor was identified as light rather than phosphorus by both T-N/T-P ratio and TSI indexes analysis. The results and methodology adopted in this study can be used for water quality assessment for other small ponds and lakes.

Somatic Cell Counts in Marrah Buffaloes (Bubalus bubalis) During Different Stages of Lactation, Parity and Season

  • Singh, Mahendra;Ludri, R.S.
    • Asian-Australasian Journal of Animal Sciences
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    • v.14 no.2
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    • pp.189-192
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    • 2001
  • This study was initiated in an effort to determine the normal mean and variations of the somatic cell count (SCC) in milk of buffaloes as influenced by the milking time, stage of lactation, parity and season. The buffaloes were hand milked at 13 and 11 h. interval during evening and morning respectively. On the day of milk sampling the udders were tested for mastitis by California Mastitis Test (CMT). Only those buffaloes, which were found negative in the CMT, were included in the sampling plan. The mean values for morning and evening were 1.09 (range 0.39-1.76) and $0.97(range\;0.57-2.46){\times}10^5cells/ml$, respectively which did not differ significantly. When data of the morning and evening values was compared on the basis of total cell secretion in milk, even then there was no statistical difference between the morning and the evening values, thereby suggesting that no diurnal variation existed in SCC of milk. Paritywise differences were not significant between the 1st to 5th lactation and above. Similarly stage of lactation effect, when tested at 30 day intervals, did not differ significantly. Significant (p<0.05) correlation coefficients (r) between SCC and milk yield during different stages of lactation and parity suggested that SCC per ml of milk was higher during the later stages of lactation. SCC was higher in primiparous than in multiparous buffaloes. On an average the SCC recorded was $1.0{\times}10^5cells/ml$ of milk irrespective of time of milking, parity and stages of lactation. The SCC was low during cold and hot-dry season but were high during the hot-humid season (p<0.05), the respective values being 0.76, 1.08 and $1.35{\times}10^5cells/ml$. These values were lower than the SCC already reported in cows suggesting less stressful condition of the udder of buffaloes in this study.

Effects of SULT1A1 Copy Number Variation on Estrogen Concentration and Tamoxifen-Associated Adverse Drug Reactions in Premenopausal Thai Breast Cancer Patients: A Preliminary Study

  • Charoenchokthavee, Wanaporn;Ayudhya, Duangchit Panomvana Na;Sriuranpong, Virote;Areepium, Nutthada
    • Asian Pacific Journal of Cancer Prevention
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    • v.17 no.4
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    • pp.1851-1855
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    • 2016
  • Tamoxifen is a pharmacological estrogen inhibitor that binds to the estrogen receptor (ER) in breast cells. However, it shows an estrogenic effect in other organs, which causes adverse drug reactions (ADRs). The sulfotransferase 1A1 (SULT1A1) enzyme encoded by the SULT1A1 gene is involved in estrogen metabolism. Previous research has suggested that the SULT1A1 copy number is linked with the plasma estradiol (E2) concentration. Here, a total of 34 premenopausal breast cancer patients, selected from the Thai Tamoxifen (TTAM) Project, were screened for their SULT1A1 copy number, plasma E2 concentration and ADRs. The mean age was $44.3{\pm}11.1years$, and they were subtyped as ER+/progesterone receptor (PR)+ (28 patients), ER+/PR- (5 patients) and ER-/PR- (1 patient). Three patients reported ADRs, which were irregular menstruation (2 patients) and vaginal discharge (1 patient). Most (33) patients had two SULT1A1 copies, with one patient having three copies. The median plasma E2 concentration was 1,575.6 (IQR 865.4) pg/ml. Patients with ADRs had significantly higher plasma E2 concentrations than those patients without ADRs (p = 0.014). The plasma E2 concentration was numerically higher in the patient with three SULT1A1 copies, but this lacked statistical significance.

SRD5A2 Gene Polymorphisms and the Risk of Benign Prostatic Hyperplasia but not Prostate Cancer

  • Choubey, Vimal Kumar;Sankhwar, Satya Narayan;Carlus, S. Justin;Singh, Anand Narayan;Dalela, Divakar;Thangaraj, Kumarasamy;Rajender, Singh
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.3
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    • pp.1033-1036
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    • 2015
  • Background: Testosterone, a primary androgen in males, is converted into its most active form, dihydrotestosterone (DHT), by $5{\alpha}$-reductase type 2 (encoded by the SRD5A2 gene) in the prostate. DHT is necessary for prostatic growth and has five times higher binding affinity than testosterone for androgen receptors. We hypothesized that polymorphic variations in the SRD5A2 gene may affect the risk of benign prostatic hyperplasia and prostate cancer. Materials and Methods: We analyzed SRD5A2 gene polymorphisms in 217 BPH patients, 192 PCa cases, and 171 controls. Genotyping was undertaken using direct DNA sequencing. Genotype data were compared between cases and controls using a Chi square statistical tool. Results: We found that the A49T locus was monomorphic with 'AA' genotype in all subjects. At V89L locus, the presence of 'VV' showed a marginally significant correlation with increased BPH risk (p=0.047). At the $(TA)_n$ locus, longer TA repeats were found to be protective against BPH (p=0.003). However, neither of these polymoprhisms correlated with the risk of PCa. Conclusions: We conclude that A49T is monomorphic in the study population, VV marginally correlates with BPH risk, and longer $(TA)_n$ repeats are protective against BPH. None of these polymorphisms affect the risk of PCa.

Nutritional Metabolomics (영양 대사체학)

  • Hong, Young-Shick
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.43 no.2
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    • pp.179-186
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    • 2014
  • Metabolomics is the study of changes in the metabolic status of an organism as a consequence of drug treatment, environmental influences, nutrition, lifestyle, genetic variations, toxic exposure, disease, stress, etc, through global or comprehensive identification and quantification of every single metabolite in a biological system. Since most chronic diseases have been demonstrated to be linked to nutrition, nutritional metabolomics has great potential for improving our understanding of the relationship between disease and nutritional status, nutrient, or diet intake by exploring the metabolic effects of a specific food challenge in a more global manner, and improving individual health. In particular, metabolite profiling of biofluids, such as blood, urine, or feces, together with multivariate statistical analysis provides an effective strategy for monitoring human metabolic responses to dietary interventions and lifestyle habits. Therefore, studies of nutritional metabolomics have recently been performed to investigate nutrition-related metabolic pathways and biomarkers, along with their interactions with several diseases, based on animal-, individual-, and population-based criteria with the goal of achieving personalized health care in the future. This article introduces analytical technologies and their application to determination of nutritional phenotypes and nutrition-related diseases in nutritional metabolomics.

The Statistical Analysis for the fate of Antibiotic Resistance according to the Spatial and Operational Wastewater Treatment Factors (하수 처리시설의 공간 및 운전인자에 따른 항생제 내성의 통계학적 분석)

  • Kim, Sung-Pyo;Cho, Yun-Chul;Kim, Lee-Hyung;Chandran, Kartik
    • Journal of Wetlands Research
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    • v.13 no.1
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    • pp.117-127
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    • 2011
  • The aim of this study was to examine the fate of tetracycline resistant bacteria (TRB) and tetracycline resistant genes (TRG) according to the spatial and operational wastewater treatment factors. As part of the effort, TRB and TRG of water samples at each unit processes of three different wastewater treatment plants (WWTPs) were analyzed over seven month study periods. With the data about different spatial and operating conditions of these WWTPs, TRB and TRGs, principal component analysis (PCA) was performed to find out any general correlation trend. Based on the statistic analysis results, the extent of TRB concentration in the activated sludge (TRBAS) is much related to the TRB concentration in primary clarifier effluent (TRBPE). Also, the study results indicated that the fate of TRB and TRG are significantly affected by the SRT variations.

The Spatial Characteristics of Transit-Poors in Urban Areas (대중교통서비스 취약계층의 공간적 분포 특성)

  • Kim, Jae-Ik;Kang, Seung-Kyu;Kwon, Jin-Hwi
    • Journal of the Korean Association of Geographic Information Studies
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    • v.11 no.2
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    • pp.1-12
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    • 2008
  • This paper identifies public transit-poors and derives spatial characteristics of the poors' distribution in an urban area by utilizing buffering analysis of geographic information systems and remote sensing techniques in the case of Daegu metropolitan city. Since special attention is given to elderlies, this study assigns three hundred meter buffer from bus/subway station as service boundary for elderlies. The results of this study tell us that 1) the transit-poors are concentrated on suburban and rural regions, 2) high proportions of the transit poors are elderlies with spatial variations in many regions, 3) the main housing type of the transit-poors is single detached house. We expect that this study can contribute to build an effective policy-making by showing essential technical processes and methods in identifying policy-need groups and their characteristics of spatial distribution.

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Distributional Characteristics of Volatile Organic Compounds in the Indoor Air of Various Office Environments (다양한 사무실 실내환경에서의 휘발성유기화합물의 농도분포 특성)

  • Baek, Sung-Ok;Jeon, Chan-Gon
    • Journal of Korean Society for Atmospheric Environment
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    • v.30 no.5
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    • pp.477-491
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    • 2014
  • This study was carried out to evaluate the concentration variations of volatile organic compounds (VOCs) in the office environments located in a large urban area with respect to seasonality, smoking status, types of ventilation and heating. Indoor air sampling was undertaken in 37 and 30 offices in Daegu city during summer and winter, respectively. The VOC samples were collected using adsorbent tubes, and were determined by thermal desorption coupled with GC/MS analysis. The analytical method was validated for repeatability, method detection limits (MDL), and duplication precision. A total of 34 VOCs of environmental concern were determined, including 15 aromatics and 19 halogenated hydrocarbons. Average concentrations of BTEX appeared to 1.91 ppb, 22.98 ppb, 3.44 ppb, and 3.70 ppb, respectively. These values were relatively higher levels than those measured at homes and outdoor roadsides reported by other researches. In general, the concentrations of VOCs were higher in winter than summer, in smoking offices than non-smoking offices, in forced ventilation type than natural ventilation type, and in combustion heating than non-combustion heating offices. However, such differences were not always significant at a level of 0.05 by statistical tests (t-test and/or Mann-Whitney test) with some exceptions for BTEX and styrene. This study demonstrated that smoking status, ventilation type and presence of combustion sources indoors could be important factors on the elevated concentrations of some VOCs in the office environment.