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Piezo-assisted Intracytoplasmic Sperm Injection in Cattle

  • Kim, Se-Woong;Kang, Ho-In;Sung, Ji-Hye;Roh, Sang-Ho
    • Journal of Embryo Transfer
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    • v.25 no.2
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    • pp.97-101
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    • 2010
  • Intracytoplasmic sperm injection (ICSI) is one of the artificial fertilization methods when only a few sperm are available for insemination, and an important tool for the preservation of genetic materials of endangered animal species, especially the male is infertile. Different from other species such as mice and pigs, the conventional ICSI method which uses spiked pipette for injection (Spike-ICSI) is exhibited low success rates in cattle because the bovinesperm head membrane is hard to break during injection procedure. We chose piezo-assisted ICSI (Piezo-ICSI) for the improvement of the injection procedure including sperm head membrane rupture and efficient puncture of the plasma membrane of the oocytes. In this experiment, we compared the efficacy of the bovine ICSI embryo production between the Piezo-ICSI and Spike-ICSI. The second polar body extrusion, pronuclear formation, cleavage and blastocyst formation were evaluated after implementation of two different ICSI techniques. The Piezo-ICSI tended to show comparably higher rates of the second polar body extrusion (41.7%), the pronuclei formation (42.9%) and the two-cell cleavage (41.4%) than Spike-ICSI does (33.3%, 28.6% and 23.5%, respectively) although there is no statistic significance between two groups. In addition, the blastocysts were only obtained from the Piezo-ICSI group (10.3%). Our finding shows that the Piezo-ICSI may be used as an artificial fertilization method in cattle when in vitro fertilization is not applicable.

Analysis of Consulting Research Trends Using Topic Modeling (토픽 모델링을 활용한 컨설팅 연구동향 분석)

  • Kim, Min Kwan;Lee, Yong;Han, Chang Hee
    • Journal of Korean Society of Industrial and Systems Engineering
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    • v.40 no.4
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    • pp.46-54
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    • 2017
  • 'Consulting', which is the main research topic of the knowledge service industry, is a field of study that is essential for the growth and development of companies and proliferation to specialized fields. However, it is difficult to grasp the current status of international research related to consulting, mainly on which topics are being studied, and what are the latest research topics. The purpose of this study is to analyze the research trends of academic research related to 'consulting' by applying quantitative analysis such as topic modeling and statistic analysis. In this study, we collected statistical data related to consulting in the Scopus DB of Elsevier, which is a representative academic database, and conducted a quantitative analysis on 15,888 documents. We scientifically analyzed the research trends related to consulting based on the bibliographic data of academic research published all over the world. Specifically, the trends of the number of articles published in the major countries including Korea, the author key word trend, and the research topic trend were compared by country and year. This study is significant in that it presents the result of quantitative analysis based on bibliographic data in the academic DB in order to scientifically analyze the trend of academic research related to consulting. Especially, it is meaningful that the traditional frequency-based quantitative bibliographic analysis method and the text mining (topic modeling) technique are used together and analyzed. The results of this study can be used as a tool to guide the direction of research in consulting field. It is expected that it will help to predict the promising field, changes and trends of consulting industry related research through the trend analysis.

Building credit scoring models with various types of target variables (목표변수의 형태에 따른 신용평점 모형 구축)

  • Woo, Hyun Seok;Lee, Seok Hyung;Cho, HyungJun
    • Journal of the Korean Data and Information Science Society
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    • v.24 no.1
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    • pp.85-94
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    • 2013
  • As the financial market becomes larger, the loss increases due to the failure of the credit risk managements from the poor management of the customer information or poor decision-making. Thus, the credit risk management also becomes more important and it is essential to develop a credit scoring model, which is a fundamental tool used to minimize the credit risk. Credit scoring models have been studied and developed only for binary target variables. In this paper, we consider other types of target variables such as ordinal multinomial data or longitudinal binary data and suggest credit scoring models. We then apply our developed models to real data and random data, and investigate their performance through Kolmogorov-Smirnov statistic.

Goodness-of-fit test for normal distribution based on parametric and nonparametric entropy estimators (모수적 엔트로피 추정량과 비모수적 엔트로피 추정량에 기초한 정규분포에 대한 적합도 검정)

  • Choi, Byungjin
    • Journal of the Korean Data and Information Science Society
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    • v.24 no.4
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    • pp.847-856
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    • 2013
  • In this paper, we deal with testing goodness-of-fit for normal distribution based on parametric and nonparametric entropy estimators. The minimum variance unbiased estimator for the entropy of the normal distribution is derived as a parametric entropy estimator to be used for the construction of a test statistic. For a nonparametric entropy estimator of a data-generating distribution under the alternative hypothesis sample entropy and its modifications are used. The critical values of the proposed tests are estimated by Monte Carlo simulations and presented in a tabular form. The performance of the proposed tests under some selected alternatives are investigated by means of simulations. The results report that the proposed tests have better power than the previous entropy-based test by Vasicek (1976). In applications, the new tests are expected to be used as a competitive tool for testing normality.

Instruction Level Resource Usage Analysis Method for Embedded Systems (임베디드 시스템에서 명령어 기반의 자원 사용 분석 방법)

  • Cho, Jae-hwang;Jung, Hun;Shin, Dong-Ha;Son, Sung-Hoon
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • v.9 no.2
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    • pp.436-439
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    • 2005
  • As mobile computers and embedded systems are becoming popular recently, we need to study how to utilize the resources such as power, space, CPU clocks, and memory efficiently. In traditional embedded system development, we were interested in resource usage based on hardware but, as software is becoming more important, we need to study how to analyze the resource usage based on software. In this research, we propose a new method called 'Instruction Level Resource Usage Analysis Method' and implement it as a resource usage analysis tool called 'I-Debugger'. I-Debugger is constructed on three layers: debugging layer which controls the execution of software on instruction level, statistic layer which gathers real-time data and convert to useful information, and analysis layer which generate useful information to specific applications. We have applied the debugger to some simple problem and found that our method is useful in developing resource efficient embedded systems.

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Design and Implementation of a Web-Based Education-Evaluation System for Setting and Analyzing Questions (문항출제와 문항분석이 가능한 웹기반 교육평가 시스템의 설계 및 구현)

  • Ha, Il-Gyu;Gang, Byeong-Uk
    • The KIPS Transactions:PartD
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    • v.9D no.3
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    • pp.511-522
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    • 2002
  • WBI (Web-Based Instruction), a web-based tool for teaching the students at a long distance, makes possible to Interact between learners and instructors, provides a wide variety of learning materials, has an advantage of overcoming spatial constraints. In this paper, as a model of using the web for education, a web-based education-evaluation system has been designed and implemented. Web-based education-evaluation system has to be equipped with both of the online setting question mode and the upload setting question mode, the former makes questions on web and the latter uploads the setted questions on offline with settling a defeat of the existing systems on setting questions. And the system has to be equipped with the function of analyzing the questions that gives teacher several kinds of analysis information and makes possible to feedback to questions by adjusting the difficulty and revising the questions. In this paper, a system that reflects the above requirements has been designed and implemented with PHP script language and MySQL database system.

Inter-rater Reliability Study on Pattern Identification Using Nasal Endoscopy for Rhinitis (비내시경 활용 비염 변증 지표의 평가자 간 신뢰도 연구)

  • Min, Kyung-Jin;Son, Mi-Ju;Kim, Young-Eun;Kim, Jeong-Hun;Lee, Dong-Hyo
    • The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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    • v.30 no.4
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    • pp.97-103
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    • 2017
  • Objectives : To identify whether pattern identification using nasal endoscopy for rhinitis can be applied as a tool for evaluating rhinitis in routine care setting, we performed a inter-rater reliability study on this pattern identification. Methods : Two Korean medicine doctors assessed 290 left/right nasal endoscopy photograph cases of rhinitis patients with pattern identification using nasal endoscopy. This pattern identification consist of four assessment items, nasal membrane color(pale/hyperemia), nasal membrane humidity(dryness/dampness), rhinorrhea(watery/yellow), and turbinate membrane edema(atrophic/edematous). Cohen's kappa statistic and Percentage agreement were used to evaluate the inter-rater reliability. Results : Inter-rater percentage agreement and Kappa coefficient for left nasal endoscopy photograph cases was from 'slight' to 'moderate'(% agreement: 40.00-67.59%/Kappa: 0.06-0.407). Only the agreement of 'rhinorrhea (watery/yellow)' item was moderate(% agreement: 67.59%/Kappa: 0.407). Inter-rater percentage agreement and Kappa coefficient for right nasal endoscopy photograph cases was also from 'slight' to 'moderate'(% agreement: 42.41-68.97%/Kappa: 0.109-0.465). Only the agreement of 'rhinorrhea(watery/yellow)' item was moderate(% agreement: 68.97%/Kappa: 0.465). Conclusions : It is necessary to resolve problems such as cut-off value setting, bipolar evaluation values(pale/hyperemia, dryness/dampness, watery/yellow, atrophic/edematous) and weighting items. Further rigorous studies that overcome the limitations of the current research are warranted.

Variable selection for latent class analysis using clustering efficiency (잠재변수 모형에서의 군집효율을 이용한 변수선택)

  • Kim, Seongkyung;Seo, Byungtae
    • The Korean Journal of Applied Statistics
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    • v.31 no.6
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    • pp.721-732
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    • 2018
  • Latent class analysis (LCA) is an important tool to explore unseen latent groups in multivariate categorical data. In practice, it is important to select a suitable set of variables because the inclusion of too many variables in the model makes the model complicated and reduces the accuracy of the parameter estimates. Dean and Raftery (Annals of the Institute of Statistical Mathematics, 62, 11-35, 2010) proposed a headlong search algorithm based on Bayesian information criteria values to choose meaningful variables for LCA. In this paper, we propose a new variable selection procedure for LCA by utilizing posterior probabilities obtained from each fitted model. We propose a new statistic to measure the adequacy of LCA and develop a variable selection procedure. The effectiveness of the proposed method is also presented through some numerical studies.

Effect-Evaluation of Korean Traditional Food Culture Education Program for the elementary schoolers (초등학교 학생들을 위한 전통음식문화 교육 프로그램의 효과 평가)

  • Cha, Jin-A;Yang, Il-Sun;Chung, La-Na;Lee, So-Jung
    • Journal of the Korean Society of Food Culture
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    • v.22 no.4
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    • pp.383-392
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    • 2007
  • The object of this study is to evaluate the Korean traditional food culture education program which was developed in the prior study. In order to evaluate the effect of the program on the students’ knowledge of traditional food culture and their food habit, the program was practiced for 82 students in 4 elementary schools located in Seoul and Kyungki province during 16 weeks from Mar 1, 2005 to July 23, 2005. The pretest and the post-test were performed using an evaluation tool which is composed of evaluation sections for the perception and knowledge of the Korean traditional food culture, Korean children’s food habit and food preference for the Korean traditional food and fast food. The validity of evaluation was proved through the control group in the pretest and the post-test. Descriptive analysis and paired t-test were performed using SPSS/WIN 12.0 Statistic Package in order to compare the results of the pretest with those of the post-test after the education. The perception of the students who took the class for the Korean traditional food was slightly improved (p<0.05) and their knowledge was also increased (p<0.001) after the education while no difference was found in the control group. Moreover, the subjects’ food habit (p<0.001) and their preference of the Korean traditional food (p<.05) were increased respectively but their preference of the Western fast food was decreased(p<.01). These results indicate that the education program evaluated in this study has the effect of altering the subjects’ food habit or food preference as well as of introducing the knowledge of the Korean traditional food culture.

A Study of the Effect of an Avatar Encouraging Drinking in Virtual Reality on Alcohol Craving (가상현실에서의 아바타 음주권유가 갈망감 유발에 미치는 영향에 관한 연구)

  • Choi, You-Kyung;Cho, Sang-Woo;Han, Ki-Wan;Ku, Jeong-Hun;Jung, Young-Chul;Kim, Jae-Jin;Kee, NamKoong;Kim, In-Yong
    • 한국HCI학회:학술대회논문집
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    • 2008.02a
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    • pp.823-828
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    • 2008
  • This study set out investigate what kind of changes would be caused to the craving of alcohol dependent patients by stimuli through virtual reality in the preparation stage for drinking refusal training. With regard to stimulation, it included alcohol exposure, a positive situation, and a negative situation on the basis of drinking encouraging situations(social pressure) known as drinking stimulating situations for alcoholics. The purpose of the study is to provide fundamental materials for the development of new training programs to refuse alcohol and for the examination of the possibility of utilizing virtual reality technology as a new treatment and training tool for alcoholics. To this end, a virtual reality program was conducted involving 12 alcoholics admitted to Severance Mental Health Hospital in Gyeonggi province from December 2006 to September 2007. The data was dealt with various statistic analyses such as frequency analysis, Wilcoxon Matched-pairs Signed-Ranks Test using SPSS/WIN 11.5 The analysis results indicate that avatars encouraging drinking caused more craving than just the background, that the scenes with alcohol exposed caused more craving than the scenes with no alcohol exposed, and that there were no significant changes to craving according to a positive or negative situation. The results confirmed that training sessions using virtual reality presented a situation and environment of drinking pressure that's similar to the actual social pressure and that the virtual reality approach had enormous potential as an effective treatment tool when combined with the existing treatment techniques.

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