• Journal of Interdisciplinary Genomics
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• v.5 no.2
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• pp.18-23
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• 2023

Conventional evaluation method for identifying the organic cause of short stature has a low detection rate. If an infant who is small for gestational age manifests postnatal growth deterioration, triangular face, relative macrocephaly, and protruding forehead, a genetic testing of IGF2, H19, GRB10, MEST, CDKN1, CUL7, OBSL1, and CCDC9 should be considered to determine the presence of Silver-Russell syndrome and 3-M syndrome. If a short patient with prenatal growth failure also exhibits postnatal growth failure, microcephaly, low IGF-1 levels, sensorineural deafness, or impaired intellectual development, genetic testing of IGF1 and IGFALS should be conducted. Furthermore, genetic testing of GH1, GHRHR, HESX1, SOX3, PROP1, POU1F1, and LHX3 should be considered if patients with isolated growth hormone deficiency have short stature below -3 standard deviation score, barely detectable serum growth hormone concentration, and other deficiencies of anterior pituitary hormone. In short patients with height SDS <-3 and high growth hormone levels, genetic testing should be considered to identify GHR mutations. Lastly, when severe short patients (height z score <-3) exhibit high levels of prolactin and recurrent pulmonary infection, genetic testing should be conducted to identify STAT5B mutations.

• Safety and Health at Work
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• v.8 no.4
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• pp.364-370
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• 2017

Background: Labeled noise reduction (NR) data presented by manufacturers are considered one of the main challenging issues for occupational experts in employing hearing protection devices (HPDs). This study aimed to determine the actual NR data of typical HPDs using the objective fit testing method with a microphone in real ear (MIRE) method. Methods: Five available commercially earmuff protectors were investigated in 30 workers exposed to reference noise source according to the standard method, ISO 11904-1. Personal attenuation rating (PAR) of the earmuffs was measured based on the MIRE method using a noise dosimeter (SVANTEK, model SV102). Results: The results showed that means of PAR of the earmuffs are from 49% to 86% of the nominal NR rating. The PAR values of earmuffs when a typical eyewear was worn differed statistically (p < 0.05). It is revealed that a typical safety eyewear can reduce the mean of the PAR value by approximately 2.5 dB. The results also showed that measurements based on the MIRE method resulted in low variability. The variability in NR values between individuals, within individuals, and within earmuffs was not the statistically significant (p > 0.05). Conclusion: This study could provide local individual fit data. Ergonomic aspects of the earmuffs and different levels of users experience and awareness can be considered the main factors affecting individual fitting compared with the laboratory condition for acquiring the labeled NR data. Based on the obtained fit testing results, the field application of MIRE can be employed for complementary studies in real workstations while workers perform their regular work duties.

• Proceedings of the Korea Concrete Institute Conference
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• 2004.05a
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• pp.652-655
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• 2004

In these days, repair materials for leakage cannot help but being taken in temporary way without any noticeable countermeasure. This kind of repair is socially criticized many times that is defective construction even if tills costs a lot. It was not arrange the standard for performance evaluation test method and quality maintenance for materials, even it has been used various injection repairing agent. In conclusion, We suggest that the test method for repair materials for leakage to establish the leakage repairing technology as increase of structure demand, so that the necessity of the establishment of the quality control standard and the performance testing way on the relevant water-proof seal is increasing a lot to regulate the water-proof technology and the leakage repair technology.

• Journal of Electrical Engineering and information Science
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• v.2 no.5
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• pp.1-8
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• 1997

The main purpose of the Boolean equivalence problem is to verify that two Boolean expressions have the same functionality. Simulation has been extensively used as the standard method for the equivalence problem. Obviously, the number of tests required to perform a satisfactory coverage grows exponentially with the number of input variables. However, formal methods as opposed to simulation are getting more attention from the community. We propose a new algorithm called the Cover-Merge Algorithm based on a derivational method using the concept of cover and merge for the equivalence problem and investigate its theoretical aspects. Because of the difficulty of the problem, we emphasize simplification techniques in order to reduce the search space or problem size. Heuristics based on types of merges are developed to speed up the derivation process by allowing simplifications. In comparison with widely used technique called Binary Decision Diagram or BDD, the algorithm proposed outperforms BDD in nearly all cases of input including standard benchmark problems.

• Journal of the Institute of Convergence Signal Processing
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• v.11 no.4
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• pp.303-309
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• 2010

We proposes a new approach for testing the self visual-acuity by using the KS standard optotype. The proposed system provides their hand-gesture recognition method for the convenient response of subjects in the visual acuity measurement. Also, this system can measure a visual-acuity that excludes the examiner's subjective judgement or the subject's memorized guess, because of presenting a random optotype automatically by computer without a examiner. Especially, Our system guarantees the reliability by using the KS standard optotype and its presentation(KS P ISO 8596), which is defined by the Korea Standards Association in 2006. And the database management function of our system can provide the visual-acuity data to the EMR client easily. As a result, Our system shows the 98% consistency in the limit of the ${\pm}1$ visual-acuity level error by comparing the visual-acuity chart test.

• Proceedings of the Korea Electromagnetic Engineering Society Conference
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• 2005.11a
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• pp.409-414
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• 2005

This study is based on the recent CISPR(International Special Committee on Radio Interference) research which is focused on the Radiated Emission test method above 1 GHz and explained "w"(Measurements dimension) for the antenna's $\theta_{3dB}$ characteristic. And expound the work in progress in the IEC Standard for the measurement methods and the limits above 1 GHz.

• Journal of Food Hygiene and Safety
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• v.27 no.1
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• pp.37-41
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• 2012

The current standard for testing tetrodotoxin (TTX) in foodstuffs is the mouse bioassay (MBA) in Korea as in many other countries. However, this test suffers from potential ethical concerns over the use of live animals. In addition, the mouse bioassay does not test for a specific toxin thus a sample resulting in mouse incapacitation would need further confirmatory testing to determine the exact source toxin (e.g., TTX, STX, brevotoxin, etc.). Furthermore, though the time of death is proportional to toxicity in this assay, the dynamic range for this proportional relationship is small thus many samples must be diluted and new mice be injected to yield a result that falls within the quantitative dynamic range. Therefore, in recent years, there have been many efforts in this field to develop alternative assays. High performance liquid chromatography (HPLC) coupled with mass spectrometry (MS) has been emerged as one of the most promising options. A LC-MS-MS method involves solid-phase extraction (SPE) and followed by analysis using an electrospray in the positive ionization mode and multiple reactions monitoring (MRM). To adopt LC-MS-MS method as alternative standard for testing TTX, we performed a validation study for the quantification of TTX in puffer fish. This LC-MS-MS method showed good sensitivity as limits of detection (LOD) of $0.03{\sim}0.08{\mu}g/g$ and limits of quantification (LOQ) of $0.10{\sim}0.25{\mu}g/g$. The linearity ($r^2$) of tetrodotoxin were 0.9986~0.9997, the recovery were 80.9~103.0% and the relative standard deviations (RSD) were 4.3~13.0%. The correlation coefficient between the mouse bioassay and LC/MS/MS method was higher than 0.95.

• The KIPS Transactions:PartC
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• v.13C no.4 s.107
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• pp.435-440
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• 2006

XML encryption is to provide confidentiality service, though not limited to, for web contents. XML encryption can be applied to entire data files as opaque objects, or more frequently to various parts of XML documents, supporting various encryption granularity. It is this characteristic that makes XML encryption a more efficient alternative for data confidentiality in various web applications than is possible with SSL/TLS, IPsec, PGP, or S/MIME. It is essential for successful deployment of XML encryption to achieve interoperability among the products implementing this technology, which requires the products to implement the XML encryption standards correctly. Conformance testing is to test if products implement the relevant standard correctly. In this paper we present a conformance testing method for XML encryption products and implement it. We will first look at XML encryption standards developed by W3C, and extract test criteria. Then we propose a testing method in which the encryption capability and the decryption capability of a product are tested separately. The proposed methody is actually implemented as a GUI-based testing tool and some test results are presented.

• Journal of Adhesion and Interface
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• v.5 no.2
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• pp.14-26
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• 2004

For reliable determination of mechanical characteristics of adhesively bonded joints used e.g. as input data for computer-aided design of complex components, the thick-adherend tensile-shear test according to ISO 11003-2 is the most important material testing method. Although the total displacement of the joint is measured across the polymer layer directly in the overlap zone in order to minimize the influence of the stepped adherends, the substrate deformation must be taken into account within the framework of the evaluation of the shear modulus and the maximum shear strain, at least when high-strength adhesives are applied. In the standard ISO 11003-2 version of 1993, it was prescribed to perform the substrate deformation correction by means of testing a one-piece reference specimen. The authors, however, pointed to the excessive demands on the measuring accuracy of the extensometers connected with this technique in industrial practice and alternatively proposed a numerical deformation analysis of a dummy specimen. This idea of a mathematical correction was included in the revised ISO 11003-2 version of 2001 but in the simplified form of an analytical method based on Hooke's law of elasticity for small strains. In the present work, it is shown that both calculation techniques yield considerably discordant results. As experimental assessment would require high-precision distance determination (e.g. laser extensometer), finite element analyses of the deformation behavior of the bonded joint are performed in order to estimate the accuracy of the obtained substrate deformation corrections. These simulations reveal that the numerical correction technique based on the finite element deformation modeling of the reference specimen leads to considerably more realistic results.

• Analytical Science and Technology
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• v.25 no.6
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• pp.395-401
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• 2012

This study presents a method for the quantitative analysis of residual vinyl chloride monomer (VCM) in PVC products. In elution solvent, the extraction efficiency was similar by ethanol, THF, and acetone, but using n-hexane, it indicated relatively low extraction efficiency. Measuring VCM in the pulverized PVC samples, it showed reasonable results in both the direct injection method and headspace method with GC/MS. Regarding analysis of VCM in the intermediate sponge samples, five laboratories showed good results, and from the results, it was considered that VCM quantitative method in this study was reliable.